4USG | Genus

Total Genus 16

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	16
sequence length	66
structure length	66
Chain Sequence	AMFQIGKMRYVSVRDFKGKVLIDIREYYMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4. pubmed doi rcsb
molecule keywords	ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15
molecule tags	Transcription
source organism	Homo sapiens
total genus	16
structure length	66
sequence length	66
chains with identical sequence	B
ec nomenclature
pdb deposition date	2014-07-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02229	PC4	Transcriptional Coactivator p15 (PC4)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.30.31.10	Mainly Beta	Roll	Transcriptional Co-activator pc4; Chain A	Transcriptional Coactivator Pc4; Chain A	4usgA00

4BHMA 2IT9A 3N1JA 2PHEA 1L3AA 4KOQA 1PCFA 3N1HA 3N1KA 3N1IA 3R9YA 4USGA 2NVNA 3N1LA 2C62A 4KOOA 4KOPA 4BG7A 3RA0A 4AGHA 3R9ZA
chains in the Genus database with same CATH superfamily

4BHMA 2M4FA 2GIDB 2IT9A 3N1JA 3MTVA 4BXMA 2PHEA 4BODA 4BOBA 4BF3A 1L3AA 4KOQA 2GIDA 5FGPA 1PCFA 3N1HA 3N1KA 3N1IA 3R9YA 4USGA 2NVNA 2GIAB 3N1LA 3CM1A 2C62A 2GJEA 4KOOA 4KOPA 2GJED 4BG7A 3RA0A 3K44A 4AGHA 3OBHA 3R9ZA 2GIAA 4J38A
chains in the Genus database with same CATH topology

4BHMA 2IT9A 3N1JA 2PHEA 1L3AA 4KOQA 1PCFA 3N1HA 3N1KA 3N1IA 3R9YA 4USGA 2NVNA 3N1LA 2C62A 4KOOA 4KOPA 4BG7A 3RA0A 4AGHA 3R9ZA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4BHM A;  2IT9 A;  3N1J A;  2PHE A;  1L3A A;  4KOQ A;  1PCF A;  3N1H A;  3N1K A;  3N1I A;  3R9Y A;  4USG A;  2NVN A;  3N1L A;  2C62 A;  4KOO A;  4KOP A;  4BG7 A;  3RA0 A;  4AGH A;  3R9Z A; 
#chains in the Genus database with same CATH topology
 4BHM A;  2M4F A;  2GID B;  2IT9 A;  3N1J A;  3MTV A;  4BXM A;  2PHE A;  4BOD A;  4BOB A;  4BF3 A;  1L3A A;  4KOQ A;  2GID A;  5FGP A;  1PCF A;  3N1H A;  3N1K A;  3N1I A;  3R9Y A;  4USG A;  2NVN A;  2GIA B;  3N1L A;  3CM1 A;  2C62 A;  2GJE A;  4KOO A;  4KOP A;  2GJE D;  4BG7 A;  3RA0 A;  3K44 A;  4AGH A;  3OBH A;  3R9Z A;  2GIA A;  4J38 A; 
#chains in the Genus database with same CATH homology
 4BHM A;  2IT9 A;  3N1J A;  2PHE A;  1L3A A;  4KOQ A;  1PCF A;  3N1H A;  3N1K A;  3N1I A;  3R9Y A;  4USG A;  2NVN A;  3N1L A;  2C62 A;  4KOO A;  4KOP A;  4BG7 A;  3RA0 A;  4AGH A;  3R9Z A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4USGA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations