3SIJA

The x-ray crystal structure of poly(adp-ribose) glycohydrolase e115a mutant from thermomonospora curvata
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
Knots found
sequence length
274
structure length
265
Chain Sequence
RHSRRAIAAETVEILERGRYTAPSGRVVPIADHVAQAVRGTRLYRPEKLAVLLEGTRIEVTEETTLAAARRLTGAAGDQVACLNFASAEHPGGGFLSGAHAQEAGLARSSGLYASLRAVPQFYAFHHRQRDPLYSDHLIYSPGVPVFRDDAGRLLEEPYRVAFLTSPAPNRRAIGDLRTVEEIGRVLRGRAAKVLAAARHHGHRRLVLGAWGCGVFGNDPAQVAETFAGLLLDGGPFAGRFAHVVFAVWDTAPGAPRHAAFARRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Thermomonospora curvata
molecule keywords poly(ADP-ribose) glycohydrolase
total genus 89
structure length 265
sequence length 274
other databases KnotProt 2.0: K +31
ec nomenclature ec 3.2.1.143: Poly(ADP-ribose) glycohydrolase.
pdb deposition date 2011-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10021 DUF2263 Uncharacterized protein conserved in bacteria (DUF2263)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3sijA00
5CB3A 3GQOA 2LGRA 4KSIA 2EEEA 4JVVA 5HOLA 3EWOA 3KQXA 4JLLA 3EW5A 4ZYQA 3Q71A 3EJGA 5HIHA 4GVVA 2L8RA 4IQYA 4X2TA 4J5RA 5FSZA 5D8NA 4K3NA 3EKEA 3KR5A 4TU0A 4K0CA 1LAMA 1HJZA 3SIJA 1SPVA 3H8FA 3KR4A 4R76A 4ABLA 3EWQA 2BFQA 2FG1A 2J9AA 2ACFA 4D86A 1LAPA 2FXKA 1YD9A 2BFRA 3EWRA 5FSYA 2EWBA 4ZY1A 1ZR3A 4R7MA 3EWPA 3IIFA 2XD7A 4ZI6A 2VRIA 5CBMA 1BPMA 3GQEA 4J4ZA 1VHUA 5DUSA 4JGKA 3T8WA 4JCAA 5CMSA 3SIIA 4ZY0A 1TXZA 3GPQA 3IIDA 3V2BA 2FAVA 1BPNA 4J5SA 1NJRA 3EJFA 3IJ3A 3GPGA 3ETIA 3KZWA 4ESSA 1ZR5A 3H8EA 3JZTA 1LCPA 4J5QA 5E3BA 1BLLE 4ZY2A 5FSXA 3SIGA 1TY8A 3Q6ZA 3V45A 1GYTA 5FSUA 4ETKA 2X47A 5AILA 3JRUA 5FSVA 3PEIA 4GUAA 3VFQA 3SIHA 4ETJA 4R6TA 2DX6A 3KQZA 4ZX9A 2AFCA 5CB5A 4UMLA 4ABKA 4ZX8A 3H8GA 4GVWA 4KYBA 3GPOA 1LANA
chains in the Genus database with same CATH superfamily
5CB3A 3GQOA 2LGRA 4KSIA 2EEEA 4JVVA 5HOLA 3EWOA 3KQXA 4JLLA 3EW5A 2KQVA 4ZYQA 3Q71A 3EJGA 5HIHA 4GVVA 2L8RA 4IQYA 4X2TA 4J5RA 5FSZA 5D8NA 4K3NA 2WCTA 3EKEA 3KR5A 4TU0A 4K0CA 1LAMA 1HJZA 3SIJA 1SPVA 2W2GA 3H8FA 3KR4A 4R76A 4ABLA 3EWQA 2BFQA 2FG1A 2J9AA 2ACFA 4D86A 2JZEA 1LAPA 2FXKA 1YD9A 2BFRA 3EWRA 5FSYA 2EWBA 4ZY1A 2JZDA 1ZR3A 4R7MA 3EWPA 3IIFA 2XD7A 4ZI6A 2VRIA 5CBMA 1BPMA 3GQEA 4J4ZA 1VHUA 5DUSA 4JGKA 3T8WA 4JCAA 5CMSA 3SIIA 4ZY0A 1TXZA 2RNKA 3GPQA 3IIDA 3V2BA 2FAVA 1BPNA 4J5SA 1NJRA 3EJFA 3IJ3A 3GPGA 3ETIA 3KZWA 4ESSA 1ZR5A 3H8EA 3JZTA 1LCPA 4J5QA 5E3BA 1BLLE 4ZY2A 5FSXA 3SIGA 1TY8A 3Q6ZA 3V45A 1GYTA 2JZFA 5FSUA 4ETKA 2X47A 5AILA 3JRUA 5FSVA 3PEIA 4GUAA 3VFQA 3SIHA 4ETJA 4R6TA 2DX6A 3KQZA 4ZX9A 2AFCA 5CB5A 4UMLA 4ABKA 4ZX8A 3H8GA 4GVWA 4KYBA 3GPOA 1LANA
chains in the Genus database with same CATH topology
5CB3A 3GQOA 2LGRA 4KSIA 2EEEA 4JVVA 5HOLA 3EWOA 3KQXA 4JLLA 3EW5A 4ZYQA 3Q71A 3EJGA 5HIHA 4GVVA 2L8RA 4IQYA 4X2TA 4J5RA 5FSZA 5D8NA 4K3NA 3EKEA 3KR5A 4TU0A 4K0CA 1LAMA 1HJZA 3SIJA 1SPVA 3H8FA 3KR4A 4R76A 4ABLA 3EWQA 2BFQA 2FG1A 2J9AA 2ACFA 4D86A 1LAPA 2FXKA 1YD9A 2BFRA 3EWRA 5FSYA 2EWBA 4ZY1A 1ZR3A 4R7MA 3EWPA 3IIFA 2XD7A 4ZI6A 2VRIA 5CBMA 1BPMA 3GQEA 4J4ZA 1VHUA 5DUSA 4JGKA 3T8WA 4JCAA 5CMSA 3SIIA 4ZY0A 1TXZA 3GPQA 3IIDA 3V2BA 2FAVA 1BPNA 4J5SA 1NJRA 3EJFA 3IJ3A 3GPGA 3ETIA 3KZWA 4ESSA 1ZR5A 3H8EA 3JZTA 1LCPA 4J5QA 5E3BA 1BLLE 4ZY2A 5FSXA 3SIGA 1TY8A 3Q6ZA 3V45A 1GYTA 5FSUA 4ETKA 2X47A 5AILA 3JRUA 5FSVA 3PEIA 4GUAA 3VFQA 3SIHA 4ETJA 4R6TA 2DX6A 3KQZA 4ZX9A 2AFCA 5CB5A 4UMLA 4ABKA 4ZX8A 3H8GA 4GVWA 4KYBA 3GPOA 1LANA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CB3 A;  3GQO A;  2LGR A;  4KSI A;  2EEE A;  4JVV A;  5HOL A;  3EWO A;  3KQX A;  4JLL A;  3EW5 A;  4ZYQ A;  3Q71 A;  3EJG A;  5HIH A;  4GVV A;  2L8R A;  4IQY A;  4X2T A;  4J5R A;  5FSZ A;  5D8N A;  4K3N A;  3EKE A;  3KR5 A;  4TU0 A;  4K0C A;  1LAM A;  1HJZ A;  3SIJ A;  1SPV A;  3H8F A;  3KR4 A;  4R76 A;  4ABL A;  3EWQ A;  2BFQ A;  2FG1 A;  2J9A A;  2ACF A;  4D86 A;  1LAP A;  2FXK A;  1YD9 A;  2BFR A;  3EWR A;  5FSY A;  2EWB A;  4ZY1 A;  1ZR3 A;  4R7M A;  3EWP A;  3IIF A;  2XD7 A;  4ZI6 A;  2VRI A;  5CBM A;  1BPM A;  3GQE A;  4J4Z A;  1VHU A;  5DUS A;  4JGK A;  3T8W A;  4JCA A;  5CMS A;  3SII A;  4ZY0 A;  1TXZ A;  3GPQ A;  3IID A;  3V2B A;  2FAV A;  1BPN A;  4J5S A;  1NJR A;  3EJF A;  3IJ3 A;  3GPG A;  3ETI A;  3KZW A;  4ESS A;  1ZR5 A;  3H8E A;  3JZT A;  1LCP A;  4J5Q A;  5E3B A;  1BLL E;  4ZY2 A;  5FSX A;  3SIG A;  1TY8 A;  3Q6Z A;  3V45 A;  1GYT A;  5FSU A;  4ETK A;  2X47 A;  5AIL A;  3JRU A;  5FSV A;  3PEI A;  4GUA A;  3VFQ A;  3SIH A;  4ETJ A;  4R6T A;  2DX6 A;  3KQZ A;  4ZX9 A;  2AFC A;  5CB5 A;  4UML A;  4ABK A;  4ZX8 A;  3H8G A;  4GVW A;  4KYB A;  3GPO A;  1LAN A; 
#chains in the Genus database with same CATH topology
 5CB3 A;  3GQO A;  2LGR A;  4KSI A;  2EEE A;  4JVV A;  5HOL A;  3EWO A;  3KQX A;  4JLL A;  3EW5 A;  2KQV A;  4ZYQ A;  3Q71 A;  3EJG A;  5HIH A;  4GVV A;  2L8R A;  4IQY A;  4X2T A;  4J5R A;  5FSZ A;  5D8N A;  4K3N A;  2WCT A;  3EKE A;  3KR5 A;  4TU0 A;  4K0C A;  1LAM A;  1HJZ A;  3SIJ A;  1SPV A;  2W2G A;  3H8F A;  3KR4 A;  4R76 A;  4ABL A;  3EWQ A;  2BFQ A;  2FG1 A;  2J9A A;  2ACF A;  4D86 A;  2JZE A;  1LAP A;  2FXK A;  1YD9 A;  2BFR A;  3EWR A;  5FSY A;  2EWB A;  4ZY1 A;  2JZD A;  1ZR3 A;  4R7M A;  3EWP A;  3IIF A;  2XD7 A;  4ZI6 A;  2VRI A;  5CBM A;  1BPM A;  3GQE A;  4J4Z A;  1VHU A;  5DUS A;  4JGK A;  3T8W A;  4JCA A;  5CMS A;  3SII A;  4ZY0 A;  1TXZ A;  2RNK A;  3GPQ A;  3IID A;  3V2B A;  2FAV A;  1BPN A;  4J5S A;  1NJR A;  3EJF A;  3IJ3 A;  3GPG A;  3ETI A;  3KZW A;  4ESS A;  1ZR5 A;  3H8E A;  3JZT A;  1LCP A;  4J5Q A;  5E3B A;  1BLL E;  4ZY2 A;  5FSX A;  3SIG A;  1TY8 A;  3Q6Z A;  3V45 A;  1GYT A;  2JZF A;  5FSU A;  4ETK A;  2X47 A;  5AIL A;  3JRU A;  5FSV A;  3PEI A;  4GUA A;  3VFQ A;  3SIH A;  4ETJ A;  4R6T A;  2DX6 A;  3KQZ A;  4ZX9 A;  2AFC A;  5CB5 A;  4UML A;  4ABK A;  4ZX8 A;  3H8G A;  4GVW A;  4KYB A;  3GPO A;  1LAN A; 
#chains in the Genus database with same CATH homology
 5CB3 A;  3GQO A;  2LGR A;  4KSI A;  2EEE A;  4JVV A;  5HOL A;  3EWO A;  3KQX A;  4JLL A;  3EW5 A;  4ZYQ A;  3Q71 A;  3EJG A;  5HIH A;  4GVV A;  2L8R A;  4IQY A;  4X2T A;  4J5R A;  5FSZ A;  5D8N A;  4K3N A;  3EKE A;  3KR5 A;  4TU0 A;  4K0C A;  1LAM A;  1HJZ A;  3SIJ A;  1SPV A;  3H8F A;  3KR4 A;  4R76 A;  4ABL A;  3EWQ A;  2BFQ A;  2FG1 A;  2J9A A;  2ACF A;  4D86 A;  1LAP A;  2FXK A;  1YD9 A;  2BFR A;  3EWR A;  5FSY A;  2EWB A;  4ZY1 A;  1ZR3 A;  4R7M A;  3EWP A;  3IIF A;  2XD7 A;  4ZI6 A;  2VRI A;  5CBM A;  1BPM A;  3GQE A;  4J4Z A;  1VHU A;  5DUS A;  4JGK A;  3T8W A;  4JCA A;  5CMS A;  3SII A;  4ZY0 A;  1TXZ A;  3GPQ A;  3IID A;  3V2B A;  2FAV A;  1BPN A;  4J5S A;  1NJR A;  3EJF A;  3IJ3 A;  3GPG A;  3ETI A;  3KZW A;  4ESS A;  1ZR5 A;  3H8E A;  3JZT A;  1LCP A;  4J5Q A;  5E3B A;  1BLL E;  4ZY2 A;  5FSX A;  3SIG A;  1TY8 A;  3Q6Z A;  3V45 A;  1GYT A;  5FSU A;  4ETK A;  2X47 A;  5AIL A;  3JRU A;  5FSV A;  3PEI A;  4GUA A;  3VFQ A;  3SIH A;  4ETJ A;  4R6T A;  2DX6 A;  3KQZ A;  4ZX9 A;  2AFC A;  5CB5 A;  4UML A;  4ABK A;  4ZX8 A;  3H8G A;  4GVW A;  4KYB A;  3GPO A;  1LAN A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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