1K0EA

The crystal structure of aminodeoxychorismate synthase from formate grown crystals
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
451
structure length
437
Chain Sequence
TLSPAVITLLWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDVNARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIFCSAGGGIVADSQEEAEYQETFDKVNRILKQLEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Escherichia coli aminodeoxychorismate synthase: architectural conservation and diversity in chorismate-utilizing enzymes.
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords p-aminobenzoate synthase component I
total genus 135
structure length 437
sequence length 451
chains with identical sequence B
ec nomenclature ec 2.6.1.85: Aminodeoxychorismate synthase.
pdb deposition date 2001-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
A PF04715 Anth_synt_I_N Anthranilate synthase component I, N terminal region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 1k0eA00
3OS6A 2I6YA 3VEHA 3R76A 3R75A 3ST6A 1I7SA 5KCKA 4GRHA 1QDLA 3RV6A 5JY4A 1K0GA 1K0EA 3RV8A 5JXZA 1I7QA 2FN1A 3RV7A 5CWAA 3BZMA 2EUAA 3RV9A 3R74A 5JY9A 5JY4B 3H9MA 3GSEA 5JZDA 1I1QA 3BZNA 3LOGA 2G5FA 3HWOA 5JY8A 2FN0A
chains in the Genus database with same CATH superfamily
3OS6A 2I6YA 3VEHA 3R76A 3R75A 3ST6A 1I7SA 5KCKA 4GRHA 1QDLA 3RV6A 5JY4A 1K0GA 1K0EA 3RV8A 5JXZA 1I7QA 2FN1A 3RV7A 5CWAA 3BZMA 2EUAA 3RV9A 3R74A 5JY9A 5JY4B 3H9MA 3GSEA 5JZDA 1I1QA 3BZNA 3LOGA 2G5FA 3HWOA 5JY8A 2FN0A
chains in the Genus database with same CATH topology
3OS6A 2I6YA 3VEHA 3R76A 3R75A 3ST6A 1I7SA 5KCKA 4GRHA 1QDLA 3RV6A 5JY4A 1K0GA 1K0EA 3RV8A 5JXZA 1I7QA 2FN1A 3RV7A 5CWAA 3BZMA 2EUAA 3RV9A 3R74A 5JY9A 5JY4B 3H9MA 3GSEA 5JZDA 1I1QA 3BZNA 3LOGA 2G5FA 3HWOA 5JY8A 2FN0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OS6 A;  2I6Y A;  3VEH A;  3R76 A;  3R75 A;  3ST6 A;  1I7S A;  5KCK A;  4GRH A;  1QDL A;  3RV6 A;  5JY4 A;  1K0G A;  1K0E A;  3RV8 A;  5JXZ A;  1I7Q A;  2FN1 A;  3RV7 A;  5CWA A;  3BZM A;  2EUA A;  3RV9 A;  3R74 A;  5JY9 A;  5JY4 B;  3H9M A;  3GSE A;  5JZD A;  1I1Q A;  3BZN A;  3LOG A;  2G5F A;  3HWO A;  5JY8 A;  2FN0 A; 
#chains in the Genus database with same CATH topology
 3OS6 A;  2I6Y A;  3VEH A;  3R76 A;  3R75 A;  3ST6 A;  1I7S A;  5KCK A;  4GRH A;  1QDL A;  3RV6 A;  5JY4 A;  1K0G A;  1K0E A;  3RV8 A;  5JXZ A;  1I7Q A;  2FN1 A;  3RV7 A;  5CWA A;  3BZM A;  2EUA A;  3RV9 A;  3R74 A;  5JY9 A;  5JY4 B;  3H9M A;  3GSE A;  5JZD A;  1I1Q A;  3BZN A;  3LOG A;  2G5F A;  3HWO A;  5JY8 A;  2FN0 A; 
#chains in the Genus database with same CATH homology
 3OS6 A;  2I6Y A;  3VEH A;  3R76 A;  3R75 A;  3ST6 A;  1I7S A;  5KCK A;  4GRH A;  1QDL A;  3RV6 A;  5JY4 A;  1K0G A;  1K0E A;  3RV8 A;  5JXZ A;  1I7Q A;  2FN1 A;  3RV7 A;  5CWA A;  3BZM A;  2EUA A;  3RV9 A;  3R74 A;  5JY9 A;  5JY4 B;  3H9M A;  3GSE A;  5JZD A;  1I1Q A;  3BZN A;  3LOG A;  2G5F A;  3HWO A;  5JY8 A;  2FN0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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