2EUAA

Structure and mechanism of menf, the menaquinone-specific isochorismate synthase from escherichia coli
Total Genus 128
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
428
structure length
428
Chain Sequence
QSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWLASQQTYPQFYWQQRNGDEEAVVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDPSQGNLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIQAKEFIATLVSIKPLPGLHLTTTREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVICLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKISGNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family.
pubmed doi rcsb
molecule tags Isomerase
source organism Escherichia coli
molecule keywords Menaquinone-specific isochorismate synthase
total genus 128
structure length 428
sequence length 428
chains with identical sequence B
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2005-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 2euaA00
5JY8A 5JXZA 3RV7A 3GSEA 5JZDA 2FN1A 3HWOA 3R76A 3RV9A 1K0GA 5JY9A 3R75A 3H9MA 3ST6A 2G5FA 4GRHA 3R74A 5CWAA 3BZMA 1I7SA 5JY4A 2FN0A 5JY4B 1K0EA 3BZNA 2I6YA 3RV8A 1I7QA 5KCKA 3RV6A 3LOGA 1I1QA 3OS6A 3VEHA 1QDLA 2EUAA
chains in the Genus database with same CATH superfamily
5JY8A 5JXZA 3RV7A 3GSEA 5JZDA 2FN1A 3HWOA 3R76A 3RV9A 1K0GA 5JY9A 3R75A 3H9MA 3ST6A 2G5FA 4GRHA 3R74A 5CWAA 3BZMA 1I7SA 5JY4A 2FN0A 5JY4B 1K0EA 3BZNA 2I6YA 3RV8A 1I7QA 5KCKA 3RV6A 3LOGA 1I1QA 3OS6A 3VEHA 1QDLA 2EUAA
chains in the Genus database with same CATH topology
5JY8A 5JXZA 3RV7A 3GSEA 5JZDA 2FN1A 3HWOA 3R76A 3RV9A 1K0GA 5JY9A 3R75A 3H9MA 3ST6A 2G5FA 4GRHA 3R74A 5CWAA 3BZMA 1I7SA 5JY4A 2FN0A 5JY4B 1K0EA 3BZNA 2I6YA 3RV8A 1I7QA 5KCKA 3RV6A 3LOGA 1I1QA 3OS6A 3VEHA 1QDLA 2EUAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JY8 A;  5JXZ A;  3RV7 A;  3GSE A;  5JZD A;  2FN1 A;  3HWO A;  3R76 A;  3RV9 A;  1K0G A;  5JY9 A;  3R75 A;  3H9M A;  3ST6 A;  2G5F A;  4GRH A;  3R74 A;  5CWA A;  3BZM A;  1I7S A;  5JY4 A;  2FN0 A;  5JY4 B;  1K0E A;  3BZN A;  2I6Y A;  3RV8 A;  1I7Q A;  5KCK A;  3RV6 A;  3LOG A;  1I1Q A;  3OS6 A;  3VEH A;  1QDL A;  2EUA A; 
#chains in the Genus database with same CATH topology
 5JY8 A;  5JXZ A;  3RV7 A;  3GSE A;  5JZD A;  2FN1 A;  3HWO A;  3R76 A;  3RV9 A;  1K0G A;  5JY9 A;  3R75 A;  3H9M A;  3ST6 A;  2G5F A;  4GRH A;  3R74 A;  5CWA A;  3BZM A;  1I7S A;  5JY4 A;  2FN0 A;  5JY4 B;  1K0E A;  3BZN A;  2I6Y A;  3RV8 A;  1I7Q A;  5KCK A;  3RV6 A;  3LOG A;  1I1Q A;  3OS6 A;  3VEH A;  1QDL A;  2EUA A; 
#chains in the Genus database with same CATH homology
 5JY8 A;  5JXZ A;  3RV7 A;  3GSE A;  5JZD A;  2FN1 A;  3HWO A;  3R76 A;  3RV9 A;  1K0G A;  5JY9 A;  3R75 A;  3H9M A;  3ST6 A;  2G5F A;  4GRH A;  3R74 A;  5CWA A;  3BZM A;  1I7S A;  5JY4 A;  2FN0 A;  5JY4 B;  1K0E A;  3BZN A;  2I6Y A;  3RV8 A;  1I7Q A;  5KCK A;  3RV6 A;  3LOG A;  1I1Q A;  3OS6 A;  3VEH A;  1QDL A;  2EUA A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...