5JY4A

A high magnesium structure of the isochorismate synthase, entc
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
375
structure length
374
Chain Sequence
TLAPNRFFFMSPYRSFTTSGFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
pubmed doi rcsb
molecule tags Isomerase
source organism Escherichia coli o157:h7
molecule keywords Isochorismate synthase EntC
total genus 116
structure length 374
sequence length 375
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2016-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 5jy4A00
2FN1A 3H9MA 5CWAA 1QDLA 3R75A 3RV8A 5JY9A 3HWOA 3BZNA 3VEHA 3RV9A 3GSEA 3RV6A 3R74A 3RV7A 3R76A 1K0EA 3ST6A 5JY8A 1I7QA 3BZMA 1K0GA 5KCKA 5JXZA 5JY4B 2FN0A 2I6YA 2EUAA 3LOGA 2G5FA 5JY4A 3OS6A 1I7SA 4GRHA 1I1QA 5JZDA
chains in the Genus database with same CATH superfamily
2FN1A 3H9MA 5CWAA 1QDLA 3R75A 3RV8A 5JY9A 3HWOA 3BZNA 3VEHA 3RV9A 3GSEA 3RV6A 3R74A 3RV7A 3R76A 1K0EA 3ST6A 5JY8A 1I7QA 3BZMA 1K0GA 5KCKA 5JXZA 5JY4B 2FN0A 2I6YA 2EUAA 3LOGA 2G5FA 5JY4A 3OS6A 1I7SA 4GRHA 1I1QA 5JZDA
chains in the Genus database with same CATH topology
2FN1A 3H9MA 5CWAA 1QDLA 3R75A 3RV8A 5JY9A 3HWOA 3BZNA 3VEHA 3RV9A 3GSEA 3RV6A 3R74A 3RV7A 3R76A 1K0EA 3ST6A 5JY8A 1I7QA 3BZMA 1K0GA 5KCKA 5JXZA 5JY4B 2FN0A 2I6YA 2EUAA 3LOGA 2G5FA 5JY4A 3OS6A 1I7SA 4GRHA 1I1QA 5JZDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FN1 A;  3H9M A;  5CWA A;  1QDL A;  3R75 A;  3RV8 A;  5JY9 A;  3HWO A;  3BZN A;  3VEH A;  3RV9 A;  3GSE A;  3RV6 A;  3R74 A;  3RV7 A;  3R76 A;  1K0E A;  3ST6 A;  5JY8 A;  1I7Q A;  3BZM A;  1K0G A;  5KCK A;  5JXZ A;  5JY4 B;  2FN0 A;  2I6Y A;  2EUA A;  3LOG A;  2G5F A;  5JY4 A;  3OS6 A;  1I7S A;  4GRH A;  1I1Q A;  5JZD A; 
#chains in the Genus database with same CATH topology
 2FN1 A;  3H9M A;  5CWA A;  1QDL A;  3R75 A;  3RV8 A;  5JY9 A;  3HWO A;  3BZN A;  3VEH A;  3RV9 A;  3GSE A;  3RV6 A;  3R74 A;  3RV7 A;  3R76 A;  1K0E A;  3ST6 A;  5JY8 A;  1I7Q A;  3BZM A;  1K0G A;  5KCK A;  5JXZ A;  5JY4 B;  2FN0 A;  2I6Y A;  2EUA A;  3LOG A;  2G5F A;  5JY4 A;  3OS6 A;  1I7S A;  4GRH A;  1I1Q A;  5JZD A; 
#chains in the Genus database with same CATH homology
 2FN1 A;  3H9M A;  5CWA A;  1QDL A;  3R75 A;  3RV8 A;  5JY9 A;  3HWO A;  3BZN A;  3VEH A;  3RV9 A;  3GSE A;  3RV6 A;  3R74 A;  3RV7 A;  3R76 A;  1K0E A;  3ST6 A;  5JY8 A;  1I7Q A;  3BZM A;  1K0G A;  5KCK A;  5JXZ A;  5JY4 B;  2FN0 A;  2I6Y A;  2EUA A;  3LOG A;  2G5F A;  5JY4 A;  3OS6 A;  1I7S A;  4GRH A;  1I1Q A;  5JZD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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