1U53A

Novel x-ray structure of na-asp-2, a pr-1 protein from the nematode parasite necator americanus and a vaccine antigen for human hookworm infection
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
193
structure length
193
Chain Sequence
EFGCPDNGMSEEARQKFLEMHNSLRSSVALGQAKDGAGGNAPKAAKMKTMAYDCEVEKTAMNNAKQCVFKHSQPNQRKGLGENIFMSSDSGMDKAKAAEQASKAWFGELAEKGVGQNLKLTGGLFSRGVGHYTQMVWQETVKLGCYVEACSNMCYVVCQYGPAGNMMGKDIYEKGEPCSKCENCDKEKGLCSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Antibiotic
molecule keywords secreted protein ASP-2
publication title X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection.
pubmed doi rcsb
source organism Necator americanus
total genus 74
structure length 193
sequence length 193
ec nomenclature
pdb deposition date 2004-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00188 CAP Cysteine-rich secretory protein family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.33.10 Alpha Beta 3-Layer(aba) Sandwich Pathogenesis-related Protein p14a CAP 1u53A00
4D53A 1XTAA 3Q2RA 2GIZA 3Q2UA 4G2UA 1SMBA 4NUOA 3S6SA 3U3UC 3NT8A 1RC9A 4NUIA 5ETEA 4NUNA 1WVRA 3U3LC 4P27A 2EPFA 5JYSA 3S6UA 4AIWA 3MZ8A 4H0AA 4LY5A 4NUKA 1CFEA 1QNXA 2DDAA 1XX5A 2DDBA 3U3NC 4IFAA 4TPVA 1U53A 2VZNA 3S6VA
chains in the Genus database with same CATH superfamily
4D53A 1XTAA 3Q2RA 2GIZA 3Q2UA 4G2UA 1SMBA 4NUOA 3S6SA 3U3UC 3NT8A 1RC9A 4NUIA 5ETEA 4NUNA 1WVRA 3U3LC 4P27A 2EPFA 5JYSA 3S6UA 4AIWA 3MZ8A 4H0AA 4LY5A 4NUKA 1CFEA 1QNXA 2DDAA 1XX5A 2DDBA 3U3NC 4IFAA 4TPVA 1U53A 2VZNA 3S6VA
chains in the Genus database with same CATH topology
4D53A 1XTAA 3Q2RA 2GIZA 3Q2UA 4G2UA 1SMBA 4NUOA 3S6SA 3U3UC 3NT8A 1RC9A 4NUIA 5ETEA 4NUNA 1WVRA 3U3LC 4P27A 2EPFA 5JYSA 3S6UA 4AIWA 3MZ8A 4H0AA 4LY5A 4NUKA 1CFEA 1QNXA 2DDAA 1XX5A 2DDBA 3U3NC 4IFAA 4TPVA 1U53A 2VZNA 3S6VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D53 A;  1XTA A;  3Q2R A;  2GIZ A;  3Q2U A;  4G2U A;  1SMB A;  4NUO A;  3S6S A;  3U3U C;  3NT8 A;  1RC9 A;  4NUI A;  5ETE A;  4NUN A;  1WVR A;  3U3L C;  4P27 A;  2EPF A;  5JYS A;  3S6U A;  4AIW A;  3MZ8 A;  4H0A A;  4LY5 A;  4NUK A;  1CFE A;  1QNX A;  2DDA A;  1XX5 A;  2DDB A;  3U3N C;  4IFA A;  4TPV A;  1U53 A;  2VZN A;  3S6V A; 
#chains in the Genus database with same CATH topology
 4D53 A;  1XTA A;  3Q2R A;  2GIZ A;  3Q2U A;  4G2U A;  1SMB A;  4NUO A;  3S6S A;  3U3U C;  3NT8 A;  1RC9 A;  4NUI A;  5ETE A;  4NUN A;  1WVR A;  3U3L C;  4P27 A;  2EPF A;  5JYS A;  3S6U A;  4AIW A;  3MZ8 A;  4H0A A;  4LY5 A;  4NUK A;  1CFE A;  1QNX A;  2DDA A;  1XX5 A;  2DDB A;  3U3N C;  4IFA A;  4TPV A;  1U53 A;  2VZN A;  3S6V A; 
#chains in the Genus database with same CATH homology
 4D53 A;  1XTA A;  3Q2R A;  2GIZ A;  3Q2U A;  4G2U A;  1SMB A;  4NUO A;  3S6S A;  3U3U C;  3NT8 A;  1RC9 A;  4NUI A;  5ETE A;  4NUN A;  1WVR A;  3U3L C;  4P27 A;  2EPF A;  5JYS A;  3S6U A;  4AIW A;  3MZ8 A;  4H0A A;  4LY5 A;  4NUK A;  1CFE A;  1QNX A;  2DDA A;  1XX5 A;  2DDB A;  3U3N C;  4IFA A;  4TPV A;  1U53 A;  2VZN A;  3S6V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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