1LXYA

Crystal structure of arginine deiminase covalently linked with l-citrulline
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
409
structure length
409
Chain Sequence
SVFDSKFKGIHVYSEIGELESVLVHEPGREIDYITPARLDELLFSAILESHDARKEHKQFVAELKANDINVVELIDLVAETYDLASQEAKDKLIEEFLEDSEPVLSEEHKVVVRNFLKAKKTSRELVEIMMAGITKYDLGIEADHELIVDPMPNLYFTRDPFASVGNGVTIHYMRYKVRQRETLFSRFVFSNHPKLINTPWYYDPSLKLSIEGGDVFIYNNDTLVVGVSERTDLQTVTLLAKNIVANKECEFKRIVAINVPKWTNLMHLDTWLTMLDKDKFLYSPIANDVFKFWDYDLVNGGAEPQPVENGLPLEGLLQSIINKKPVLIPIAGEGASQMEIERETHFDGTNYLAIRPGVVIGYSRNEKTNAALEAAGIKVLPFHGNQLSLGMGNARCMSMPLSRKDVKW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of arginine deiminase with covalent reaction intermediates; implications for catalytic mechanism
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Arginine Deiminase
total genus 146
structure length 409
sequence length 409
chains with identical sequence B
ec nomenclature ec 3.5.3.6: Arginine deiminase.
pdb deposition date 2002-06-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3930.10 Mainly Alpha Orthogonal Bundle Pentein Arginine deiminase 1lxyA02
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 1lxyA01
4N2IA 4E4JA 1VKPA 2JAIA 2CI5A 2JDWA 6JDWA 5JDWA 5AK7A 2DW5A 4N2MA 3B1TA 4BOFA 5AN9I 4N2NA 8JDWA 3BPBA 4N26A 3HVMA 4N2HA 4N22A 4N2CA 1WDAA 2CMUA 1RXXA 2A9GA 2JERA 3I4AA 4YTBA 4N2BA 2ABRA 2CI6A 3JDWA 1WD9A 1JDWA 3H7CX 4X8GA 4YTGA 4N2EA 5AK8A 5HP5A 3P8EA 4DKTA 4N2AA 4N2FA 2C6ZA 1JDXA 1H70A 3I2EA 2DEXX 3H7KA 4X8CA 3RHYA 5M3QA 4N20A 4N2GA 2CI7A 3B1UA 2DEWX 4N2LA 2AAFA 1S9RA 3P8PA 1ZBRA 2JDXA 1LXYA 3APMA 2CI1A 2JAJA 1WD8A 1G61A 2Q3UA 4N2KA 4N25A 1BWDA 9JDWA 2DEYX 1G62A 2CI3A 4JDWA 4YT9A 7JDWA 4N28A 2ACIA 2EWOA 3APNA 1XKNA 4N2DA 2CI4A 4N24A
chains in the Genus database with same CATH superfamily
4N2IA 4E4JA 1VKPA 2JAIA 2CI5A 2JDWA 6JDWA 5JDWA 5AK7A 4N2MA 2DW5A 3B1TA 4BOFA 5AN9I 4N2NA 1YNIA 8JDWA 3BPBA 4N26A 3HVMA 4N2HA 4N22A 4N2CA 1WDAA 2CMUA 1RXXA 2A9GA 2JERA 3I4AA 4YTBA 4N2BA 2ABRA 2CI6A 3JDWA 1WD9A 1JDWA 3H7CX 4X8GA 4YTGA 4N2EA 5AK8A 5HP5A 3P8EA 4DKTA 4N2AA 4N2FA 2C6ZA 1JDXA 1H70A 3I2EA 2DEXX 3H7KA 4X8CA 3RHYA 5M3QA 4N20A 4N2GA 2CI7A 3B1UA 2DEWX 1YNHA 4N2LA 2AAFA 1S9RA 3P8PA 1ZBRA 2JDXA 1LXYA 3APMA 2CI1A 2JAJA 1WD8A 1G61A 2Q3UA 4N2KA 4N25A 1BWDA 9JDWA 2DEYX 1G62A 2CI3A 4JDWA 4YT9A 7JDWA 4N28A 2ACIA 2EWOA 3APNA 1XKNA 4N2DA 2CI4A 1YNFA 4N24A
chains in the Genus database with same CATH topology
4N2IA 4E4JA 1VKPA 2JAIA 2CI5A 2JDWA 6JDWA 5JDWA 5AK7A 2DW5A 4N2MA 3B1TA 4BOFA 5AN9I 4N2NA 8JDWA 3BPBA 4N26A 3HVMA 4N2HA 4N22A 4N2CA 1WDAA 2CMUA 1RXXA 2A9GA 2JERA 3I4AA 4YTBA 4N2BA 2ABRA 2CI6A 3JDWA 1WD9A 1JDWA 3H7CX 4X8GA 4YTGA 4N2EA 5AK8A 5HP5A 3P8EA 4DKTA 4N2AA 4N2FA 2C6ZA 1JDXA 1H70A 3I2EA 2DEXX 3H7KA 4X8CA 3RHYA 5M3QA 4N20A 4N2GA 2CI7A 3B1UA 2DEWX 4N2LA 2AAFA 1S9RA 3P8PA 1ZBRA 2JDXA 1LXYA 3APMA 2CI1A 2JAJA 1WD8A 1G61A 2Q3UA 4N2KA 4N25A 1BWDA 9JDWA 2DEYX 1G62A 2CI3A 4JDWA 4YT9A 7JDWA 4N28A 2ACIA 2EWOA 3APNA 1XKNA 4N2DA 2CI4A 4N24A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N2I A;  4E4J A;  1VKP A;  2JAI A;  2CI5 A;  2JDW A;  6JDW A;  5JDW A;  5AK7 A;  2DW5 A;  4N2M A;  3B1T A;  4BOF A;  5AN9 I;  4N2N A;  8JDW A;  3BPB A;  4N26 A;  3HVM A;  4N2H A;  4N22 A;  4N2C A;  1WDA A;  2CMU A;  1RXX A;  2A9G A;  2JER A;  3I4A A;  4YTB A;  4N2B A;  2ABR A;  2CI6 A;  3JDW A;  1WD9 A;  1JDW A;  3H7C X;  4X8G A;  4YTG A;  4N2E A;  5AK8 A;  5HP5 A;  3P8E A;  4DKT A;  4N2A A;  4N2F A;  2C6Z A;  1JDX A;  1H70 A;  3I2E A;  2DEX X;  3H7K A;  4X8C A;  3RHY A;  5M3Q A;  4N20 A;  4N2G A;  2CI7 A;  3B1U A;  2DEW X;  4N2L A;  2AAF A;  1S9R A;  3P8P A;  1ZBR A;  2JDX A;  1LXY A;  3APM A;  2CI1 A;  2JAJ A;  1WD8 A;  1G61 A;  2Q3U A;  4N2K A;  4N25 A;  1BWD A;  9JDW A;  2DEY X;  1G62 A;  2CI3 A;  4JDW A;  4YT9 A;  7JDW A;  4N28 A;  2ACI A;  2EWO A;  3APN A;  1XKN A;  4N2D A;  2CI4 A;  4N24 A; 
#chains in the Genus database with same CATH topology
 4N2I A;  4E4J A;  1VKP A;  2JAI A;  2CI5 A;  2JDW A;  6JDW A;  5JDW A;  5AK7 A;  4N2M A;  2DW5 A;  3B1T A;  4BOF A;  5AN9 I;  4N2N A;  1YNI A;  8JDW A;  3BPB A;  4N26 A;  3HVM A;  4N2H A;  4N22 A;  4N2C A;  1WDA A;  2CMU A;  1RXX A;  2A9G A;  2JER A;  3I4A A;  4YTB A;  4N2B A;  2ABR A;  2CI6 A;  3JDW A;  1WD9 A;  1JDW A;  3H7C X;  4X8G A;  4YTG A;  4N2E A;  5AK8 A;  5HP5 A;  3P8E A;  4DKT A;  4N2A A;  4N2F A;  2C6Z A;  1JDX A;  1H70 A;  3I2E A;  2DEX X;  3H7K A;  4X8C A;  3RHY A;  5M3Q A;  4N20 A;  4N2G A;  2CI7 A;  3B1U A;  2DEW X;  1YNH A;  4N2L A;  2AAF A;  1S9R A;  3P8P A;  1ZBR A;  2JDX A;  1LXY A;  3APM A;  2CI1 A;  2JAJ A;  1WD8 A;  1G61 A;  2Q3U A;  4N2K A;  4N25 A;  1BWD A;  9JDW A;  2DEY X;  1G62 A;  2CI3 A;  4JDW A;  4YT9 A;  7JDW A;  4N28 A;  2ACI A;  2EWO A;  3APN A;  1XKN A;  4N2D A;  2CI4 A;  1YNF A;  4N24 A; 
#chains in the Genus database with same CATH homology
 4N2I A;  4E4J A;  1VKP A;  2JAI A;  2CI5 A;  2JDW A;  6JDW A;  5JDW A;  5AK7 A;  2DW5 A;  4N2M A;  3B1T A;  4BOF A;  5AN9 I;  4N2N A;  8JDW A;  3BPB A;  4N26 A;  3HVM A;  4N2H A;  4N22 A;  4N2C A;  1WDA A;  2CMU A;  1RXX A;  2A9G A;  2JER A;  3I4A A;  4YTB A;  4N2B A;  2ABR A;  2CI6 A;  3JDW A;  1WD9 A;  1JDW A;  3H7C X;  4X8G A;  4YTG A;  4N2E A;  5AK8 A;  5HP5 A;  3P8E A;  4DKT A;  4N2A A;  4N2F A;  2C6Z A;  1JDX A;  1H70 A;  3I2E A;  2DEX X;  3H7K A;  4X8C A;  3RHY A;  5M3Q A;  4N20 A;  4N2G A;  2CI7 A;  3B1U A;  2DEW X;  4N2L A;  2AAF A;  1S9R A;  3P8P A;  1ZBR A;  2JDX A;  1LXY A;  3APM A;  2CI1 A;  2JAJ A;  1WD8 A;  1G61 A;  2Q3U A;  4N2K A;  4N25 A;  1BWD A;  9JDW A;  2DEY X;  1G62 A;  2CI3 A;  4JDW A;  4YT9 A;  7JDW A;  4N28 A;  2ACI A;  2EWO A;  3APN A;  1XKN A;  4N2D A;  2CI4 A;  4N24 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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