2AAFA

Structure of h278a arginine deiminase with l-arginine forming a s-alkylthiouronium reaction intermediate
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
412
structure length
404
Chain Sequence
TKLGVHSEAGKLRKVMVCSPGLAHQRLTPSNCDELLFDDVIWVNQAKRDHFDFVTKMRERGIDVLEMHNLLTETIQNPEALKWILDRKITADSVGLGLTSELRSWLESLEPRKLAEYLIGGVAADDLPASEGANILKMYREYLGHSSFLLPPLPNTQFTRDTTCWIYGGVTLNPMYWPARRQETLLTTAIYKFHPEFANAEFEIWYGDPDKDHGSSTLEGGDVMPIGNGVVLIGMGERSSRQAIGQVAQSLFAKGAAERVIVAGLPKSRAAMALDTVFSFCDRDLVTVFPEVVKEIVPFSLRPDPSSPYGMNIRREEKTFLEVVAESLGLKKLRVVETGREQWDDGNNVVCLEPGVVVGYDRNTYTNTLLRKAGVEVITISASELGRGRGGGHMTCPIVRDPID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Representing the Michaelis Complex and the Thiouronium Reaction Intermediate of Pseudomonas aeruginosa Arginine Deiminase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
molecule keywords Arginine deiminase
total genus 135
structure length 404
sequence length 412
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.6: Arginine deiminase.
pdb deposition date 2005-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3930.10 Mainly Alpha Orthogonal Bundle Pentein Arginine deiminase 2aafA02
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2aafA01
1H70A 2ACIA 2JAJA 1XKNA 2A9GA 1VKPA 2DEXX 3H7CX 1G62A 3B1UA 6JDWA 3I2EA 4N2LA 4N2CA 7JDWA 3I4AA 4BOFA 4N2FA 4JDWA 2EWOA 4N2HA 2CI5A 4N2MA 3APMA 2DW5A 5AK7A 4E4JA 2CMUA 3P8EA 4N2BA 4N25A 4N2EA 5JDWA 1WD8A 2JDXA 2CI4A 5AK8A 4N20A 4N2KA 1WDAA 4N2DA 2DEWX 1BWDA 1S9RA 2DEYX 4N2GA 5HP5A 5AN9I 4N24A 4N2AA 2CI6A 2AAFA 1G61A 2JAIA 9JDWA 4N26A 3RHYA 4YT9A 3B1TA 1WD9A 4N2NA 4DKTA 2CI3A 4YTBA 1JDWA 5M3QA 1LXYA 4X8CA 2Q3UA 3HVMA 2CI7A 2CI1A 2JDWA 1ZBRA 4X8GA 4N2IA 8JDWA 3P8PA 1JDXA 3APNA 4N22A 2C6ZA 2JERA 4N28A 3BPBA 2ABRA 3JDWA 4YTGA 3H7KA 1RXXA
chains in the Genus database with same CATH superfamily
1H70A 2ACIA 2JAJA 1XKNA 2A9GA 1VKPA 2DEXX 3H7CX 1G62A 3B1UA 6JDWA 3I2EA 4N2LA 4N2CA 7JDWA 3I4AA 4BOFA 4N2FA 4JDWA 2EWOA 4N2HA 2CI5A 4N2MA 3APMA 2DW5A 5AK7A 4E4JA 2CMUA 3P8EA 4N2BA 4N25A 4N2EA 5JDWA 1WD8A 2JDXA 2CI4A 5AK8A 4N20A 4N2KA 1WDAA 4N2DA 2DEWX 1BWDA 1S9RA 2DEYX 4N2GA 5HP5A 1YNIA 5AN9I 1YNFA 4N24A 4N2AA 2CI6A 2AAFA 1G61A 2JAIA 9JDWA 1YNHA 4N26A 3RHYA 4YT9A 3B1TA 1WD9A 4N2NA 4DKTA 2CI3A 4YTBA 1JDWA 5M3QA 1LXYA 4X8CA 2Q3UA 3HVMA 2CI7A 2CI1A 2JDWA 1ZBRA 4X8GA 4N2IA 8JDWA 3P8PA 1JDXA 3APNA 4N22A 2C6ZA 2JERA 4N28A 3BPBA 2ABRA 3JDWA 4YTGA 3H7KA 1RXXA
chains in the Genus database with same CATH topology
1H70A 2ACIA 2JAJA 1XKNA 2A9GA 1VKPA 2DEXX 3H7CX 1G62A 3B1UA 6JDWA 3I2EA 4N2LA 4N2CA 7JDWA 3I4AA 4BOFA 4N2FA 4JDWA 2EWOA 4N2HA 2CI5A 4N2MA 3APMA 2DW5A 5AK7A 4E4JA 2CMUA 3P8EA 4N2BA 4N25A 4N2EA 5JDWA 1WD8A 2JDXA 2CI4A 5AK8A 4N20A 4N2KA 1WDAA 4N2DA 2DEWX 1BWDA 1S9RA 2DEYX 4N2GA 5HP5A 5AN9I 4N24A 4N2AA 2CI6A 2AAFA 1G61A 2JAIA 9JDWA 4N26A 3RHYA 4YT9A 3B1TA 1WD9A 4N2NA 4DKTA 2CI3A 4YTBA 1JDWA 5M3QA 1LXYA 4X8CA 2Q3UA 3HVMA 2CI7A 2CI1A 2JDWA 1ZBRA 4X8GA 4N2IA 8JDWA 3P8PA 1JDXA 3APNA 4N22A 2C6ZA 2JERA 4N28A 3BPBA 2ABRA 3JDWA 4YTGA 3H7KA 1RXXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1H70 A;  2ACI A;  2JAJ A;  1XKN A;  2A9G A;  1VKP A;  2DEX X;  3H7C X;  1G62 A;  3B1U A;  6JDW A;  3I2E A;  4N2L A;  4N2C A;  7JDW A;  3I4A A;  4BOF A;  4N2F A;  4JDW A;  2EWO A;  4N2H A;  2CI5 A;  4N2M A;  3APM A;  2DW5 A;  5AK7 A;  4E4J A;  2CMU A;  3P8E A;  4N2B A;  4N25 A;  4N2E A;  5JDW A;  1WD8 A;  2JDX A;  2CI4 A;  5AK8 A;  4N20 A;  4N2K A;  1WDA A;  4N2D A;  2DEW X;  1BWD A;  1S9R A;  2DEY X;  4N2G A;  5HP5 A;  5AN9 I;  4N24 A;  4N2A A;  2CI6 A;  2AAF A;  1G61 A;  2JAI A;  9JDW A;  4N26 A;  3RHY A;  4YT9 A;  3B1T A;  1WD9 A;  4N2N A;  4DKT A;  2CI3 A;  4YTB A;  1JDW A;  5M3Q A;  1LXY A;  4X8C A;  2Q3U A;  3HVM A;  2CI7 A;  2CI1 A;  2JDW A;  1ZBR A;  4X8G A;  4N2I A;  8JDW A;  3P8P A;  1JDX A;  3APN A;  4N22 A;  2C6Z A;  2JER A;  4N28 A;  3BPB A;  2ABR A;  3JDW A;  4YTG A;  3H7K A;  1RXX A; 
#chains in the Genus database with same CATH topology
 1H70 A;  2ACI A;  2JAJ A;  1XKN A;  2A9G A;  1VKP A;  2DEX X;  3H7C X;  1G62 A;  3B1U A;  6JDW A;  3I2E A;  4N2L A;  4N2C A;  7JDW A;  3I4A A;  4BOF A;  4N2F A;  4JDW A;  2EWO A;  4N2H A;  2CI5 A;  4N2M A;  3APM A;  2DW5 A;  5AK7 A;  4E4J A;  2CMU A;  3P8E A;  4N2B A;  4N25 A;  4N2E A;  5JDW A;  1WD8 A;  2JDX A;  2CI4 A;  5AK8 A;  4N20 A;  4N2K A;  1WDA A;  4N2D A;  2DEW X;  1BWD A;  1S9R A;  2DEY X;  4N2G A;  5HP5 A;  1YNI A;  5AN9 I;  1YNF A;  4N24 A;  4N2A A;  2CI6 A;  2AAF A;  1G61 A;  2JAI A;  9JDW A;  1YNH A;  4N26 A;  3RHY A;  4YT9 A;  3B1T A;  1WD9 A;  4N2N A;  4DKT A;  2CI3 A;  4YTB A;  1JDW A;  5M3Q A;  1LXY A;  4X8C A;  2Q3U A;  3HVM A;  2CI7 A;  2CI1 A;  2JDW A;  1ZBR A;  4X8G A;  4N2I A;  8JDW A;  3P8P A;  1JDX A;  3APN A;  4N22 A;  2C6Z A;  2JER A;  4N28 A;  3BPB A;  2ABR A;  3JDW A;  4YTG A;  3H7K A;  1RXX A; 
#chains in the Genus database with same CATH homology
 1H70 A;  2ACI A;  2JAJ A;  1XKN A;  2A9G A;  1VKP A;  2DEX X;  3H7C X;  1G62 A;  3B1U A;  6JDW A;  3I2E A;  4N2L A;  4N2C A;  7JDW A;  3I4A A;  4BOF A;  4N2F A;  4JDW A;  2EWO A;  4N2H A;  2CI5 A;  4N2M A;  3APM A;  2DW5 A;  5AK7 A;  4E4J A;  2CMU A;  3P8E A;  4N2B A;  4N25 A;  4N2E A;  5JDW A;  1WD8 A;  2JDX A;  2CI4 A;  5AK8 A;  4N20 A;  4N2K A;  1WDA A;  4N2D A;  2DEW X;  1BWD A;  1S9R A;  2DEY X;  4N2G A;  5HP5 A;  5AN9 I;  4N24 A;  4N2A A;  2CI6 A;  2AAF A;  1G61 A;  2JAI A;  9JDW A;  4N26 A;  3RHY A;  4YT9 A;  3B1T A;  1WD9 A;  4N2N A;  4DKT A;  2CI3 A;  4YTB A;  1JDW A;  5M3Q A;  1LXY A;  4X8C A;  2Q3U A;  3HVM A;  2CI7 A;  2CI1 A;  2JDW A;  1ZBR A;  4X8G A;  4N2I A;  8JDW A;  3P8P A;  1JDX A;  3APN A;  4N22 A;  2C6Z A;  2JER A;  4N28 A;  3BPB A;  2ABR A;  3JDW A;  4YTG A;  3H7K A;  1RXX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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