2CI3A

Crystal structure of dimethylarginine dimethylaminohydrolase crystal form i
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
274
structure length
274
Chain Sequence
ATFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 99
structure length 274
sequence length 274
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2ci3A00
2DEXX 2ACIA 4N2MA 3P8PA 2CMUA 1LXYA 2Q3UA 2CI7A 1WD9A 2EWOA 2DEWX 4X8CA 2DEYX 4N2NA 3APMA 2CI4A 4YTGA 4DKTA 2DW5A 3JDWA 2ABRA 4N2DA 4N2BA 5JDWA 3H7KA 4N20A 3BPBA 7JDWA 4X8GA 3APNA 2CI1A 1BWDA 2CI5A 4E4JA 5AN9I 3HVMA 1JDWA 2JDWA 4YTBA 5AK8A 4N2CA 6JDWA 5AK7A 2JAIA 2AAFA 4N22A 2JERA 2C6ZA 1G61A 3B1TA 1WD8A 1S9RA 1JDXA 3B1UA 3I2EA 5M3QA 5HP5A 1VKPA 1H70A 2A9GA 2JAJA 4N25A 2JDXA 4N2FA 4N2IA 8JDWA 4N2AA 4BOFA 4N24A 9JDWA 4JDWA 3H7CX 3P8EA 2CI6A 1G62A 4N2EA 4N28A 4N2KA 1XKNA 3RHYA 4N2LA 1ZBRA 4N26A 2CI3A 1WDAA 3I4AA 1RXXA 4N2HA 4N2GA 4YT9A
chains in the Genus database with same CATH superfamily
2DEXX 2ACIA 4N2MA 3P8PA 2CMUA 1LXYA 2Q3UA 2CI7A 1WD9A 2EWOA 2DEWX 4X8CA 2DEYX 4N2NA 3APMA 2CI4A 4YTGA 4DKTA 2DW5A 3JDWA 2ABRA 4N2DA 4N2BA 5JDWA 1YNHA 3H7KA 4N20A 3BPBA 7JDWA 4X8GA 3APNA 1YNFA 2CI1A 1BWDA 2CI5A 4E4JA 5AN9I 3HVMA 1JDWA 2JDWA 4YTBA 5AK8A 4N2CA 6JDWA 5AK7A 2JAIA 2AAFA 4N22A 2JERA 2C6ZA 1G61A 3B1TA 1WD8A 1S9RA 1JDXA 3B1UA 1YNIA 3I2EA 5HP5A 5M3QA 1VKPA 1H70A 2A9GA 2JAJA 4N25A 2JDXA 4N2FA 4N2IA 8JDWA 4N2AA 4BOFA 4N24A 9JDWA 4JDWA 3H7CX 3P8EA 2CI6A 1G62A 4N2EA 4N28A 4N2KA 1XKNA 3RHYA 4N2LA 1ZBRA 4N26A 2CI3A 1WDAA 3I4AA 1RXXA 4N2HA 4N2GA 4YT9A
chains in the Genus database with same CATH topology
2DEXX 2ACIA 4N2MA 3P8PA 2CMUA 1LXYA 2Q3UA 2CI7A 1WD9A 2EWOA 2DEWX 4X8CA 2DEYX 4N2NA 3APMA 2CI4A 4YTGA 4DKTA 2DW5A 3JDWA 2ABRA 4N2DA 4N2BA 5JDWA 3H7KA 4N20A 3BPBA 7JDWA 4X8GA 3APNA 2CI1A 1BWDA 2CI5A 4E4JA 5AN9I 3HVMA 1JDWA 2JDWA 4YTBA 5AK8A 4N2CA 6JDWA 5AK7A 2JAIA 2AAFA 4N22A 2JERA 2C6ZA 1G61A 3B1TA 1WD8A 1S9RA 1JDXA 3B1UA 3I2EA 5M3QA 5HP5A 1VKPA 1H70A 2A9GA 2JAJA 4N25A 2JDXA 4N2FA 4N2IA 8JDWA 4N2AA 4BOFA 4N24A 9JDWA 4JDWA 3H7CX 3P8EA 2CI6A 1G62A 4N2EA 4N28A 4N2KA 1XKNA 3RHYA 4N2LA 1ZBRA 4N26A 2CI3A 1WDAA 3I4AA 1RXXA 4N2HA 4N2GA 4YT9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DEX X;  2ACI A;  4N2M A;  3P8P A;  2CMU A;  1LXY A;  2Q3U A;  2CI7 A;  1WD9 A;  2EWO A;  2DEW X;  4X8C A;  2DEY X;  4N2N A;  3APM A;  2CI4 A;  4YTG A;  4DKT A;  2DW5 A;  3JDW A;  2ABR A;  4N2D A;  4N2B A;  5JDW A;  3H7K A;  4N20 A;  3BPB A;  7JDW A;  4X8G A;  3APN A;  2CI1 A;  1BWD A;  2CI5 A;  4E4J A;  5AN9 I;  3HVM A;  1JDW A;  2JDW A;  4YTB A;  5AK8 A;  4N2C A;  6JDW A;  5AK7 A;  2JAI A;  2AAF A;  4N22 A;  2JER A;  2C6Z A;  1G61 A;  3B1T A;  1WD8 A;  1S9R A;  1JDX A;  3B1U A;  3I2E A;  5M3Q A;  5HP5 A;  1VKP A;  1H70 A;  2A9G A;  2JAJ A;  4N25 A;  2JDX A;  4N2F A;  4N2I A;  8JDW A;  4N2A A;  4BOF A;  4N24 A;  9JDW A;  4JDW A;  3H7C X;  3P8E A;  2CI6 A;  1G62 A;  4N2E A;  4N28 A;  4N2K A;  1XKN A;  3RHY A;  4N2L A;  1ZBR A;  4N26 A;  2CI3 A;  1WDA A;  3I4A A;  1RXX A;  4N2H A;  4N2G A;  4YT9 A; 
#chains in the Genus database with same CATH topology
 2DEX X;  2ACI A;  4N2M A;  3P8P A;  2CMU A;  1LXY A;  2Q3U A;  2CI7 A;  1WD9 A;  2EWO A;  2DEW X;  4X8C A;  2DEY X;  4N2N A;  3APM A;  2CI4 A;  4YTG A;  4DKT A;  2DW5 A;  3JDW A;  2ABR A;  4N2D A;  4N2B A;  5JDW A;  1YNH A;  3H7K A;  4N20 A;  3BPB A;  7JDW A;  4X8G A;  3APN A;  1YNF A;  2CI1 A;  1BWD A;  2CI5 A;  4E4J A;  5AN9 I;  3HVM A;  1JDW A;  2JDW A;  4YTB A;  5AK8 A;  4N2C A;  6JDW A;  5AK7 A;  2JAI A;  2AAF A;  4N22 A;  2JER A;  2C6Z A;  1G61 A;  3B1T A;  1WD8 A;  1S9R A;  1JDX A;  3B1U A;  1YNI A;  3I2E A;  5HP5 A;  5M3Q A;  1VKP A;  1H70 A;  2A9G A;  2JAJ A;  4N25 A;  2JDX A;  4N2F A;  4N2I A;  8JDW A;  4N2A A;  4BOF A;  4N24 A;  9JDW A;  4JDW A;  3H7C X;  3P8E A;  2CI6 A;  1G62 A;  4N2E A;  4N28 A;  4N2K A;  1XKN A;  3RHY A;  4N2L A;  1ZBR A;  4N26 A;  2CI3 A;  1WDA A;  3I4A A;  1RXX A;  4N2H A;  4N2G A;  4YT9 A; 
#chains in the Genus database with same CATH homology
 2DEX X;  2ACI A;  4N2M A;  3P8P A;  2CMU A;  1LXY A;  2Q3U A;  2CI7 A;  1WD9 A;  2EWO A;  2DEW X;  4X8C A;  2DEY X;  4N2N A;  3APM A;  2CI4 A;  4YTG A;  4DKT A;  2DW5 A;  3JDW A;  2ABR A;  4N2D A;  4N2B A;  5JDW A;  3H7K A;  4N20 A;  3BPB A;  7JDW A;  4X8G A;  3APN A;  2CI1 A;  1BWD A;  2CI5 A;  4E4J A;  5AN9 I;  3HVM A;  1JDW A;  2JDW A;  4YTB A;  5AK8 A;  4N2C A;  6JDW A;  5AK7 A;  2JAI A;  2AAF A;  4N22 A;  2JER A;  2C6Z A;  1G61 A;  3B1T A;  1WD8 A;  1S9R A;  1JDX A;  3B1U A;  3I2E A;  5M3Q A;  5HP5 A;  1VKP A;  1H70 A;  2A9G A;  2JAJ A;  4N25 A;  2JDX A;  4N2F A;  4N2I A;  8JDW A;  4N2A A;  4BOF A;  4N24 A;  9JDW A;  4JDW A;  3H7C X;  3P8E A;  2CI6 A;  1G62 A;  4N2E A;  4N28 A;  4N2K A;  1XKN A;  3RHY A;  4N2L A;  1ZBR A;  4N26 A;  2CI3 A;  1WDA A;  3I4A A;  1RXX A;  4N2H A;  4N2G A;  4YT9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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