2CI4A

Crystal structure of dimethylarginine dimethylaminohydrolase i crystal form ii
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
273
structure length
273
Chain Sequence
TFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 94
structure length 273
sequence length 273
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2ci4A00
4DKTA 4X8CA 4YTBA 1LXYA 2JAIA 3HVMA 1JDWA 2CI7A 4N2LA 3H7CX 9JDWA 4N28A 4N26A 3RHYA 3H7KA 4N2KA 1XKNA 1WD9A 2DEXX 2ABRA 4N2DA 2A9GA 5HP5A 4N2AA 2JDXA 5AN9I 1G62A 3P8PA 4N2EA 2CI6A 1G61A 3B1UA 3APNA 5AK7A 4N2FA 2AAFA 3B1TA 5AK8A 8JDWA 4X8GA 7JDWA 1BWDA 1VKPA 5M3QA 3P8EA 4N2CA 3JDWA 6JDWA 2CMUA 4BOFA 4N2GA 4N2BA 1RXXA 2JERA 5JDWA 4N25A 3APMA 4N2MA 4N22A 1WD8A 2CI4A 4N2HA 1S9RA 1WDAA 1ZBRA 4YTGA 1JDXA 2C6ZA 2JAJA 4YT9A 1H70A 2EWOA 2Q3UA 2DEYX 4N24A 2CI5A 4N2IA 2ACIA 4E4JA 2CI3A 3BPBA 2JDWA 4N20A 2CI1A 3I4AA 4JDWA 4N2NA 3I2EA 2DEWX 2DW5A
chains in the Genus database with same CATH superfamily
4DKTA 4X8CA 4YTBA 1LXYA 2JAIA 3HVMA 1JDWA 2CI7A 4N2LA 3H7CX 9JDWA 4N28A 4N26A 3RHYA 3H7KA 4N2KA 1XKNA 1WD9A 2DEXX 2ABRA 4N2DA 2A9GA 5HP5A 4N2AA 2JDXA 1YNHA 5AN9I 1G62A 3P8PA 4N2EA 2CI6A 1G61A 3B1UA 3APNA 5AK7A 4N2FA 2AAFA 3B1TA 5AK8A 8JDWA 4X8GA 7JDWA 1YNFA 1BWDA 1VKPA 5M3QA 3P8EA 4N2CA 3JDWA 6JDWA 2CMUA 4BOFA 4N2GA 4N2BA 1RXXA 2JERA 5JDWA 4N25A 3APMA 4N2MA 4N22A 1WD8A 2CI4A 4N2HA 1S9RA 1WDAA 1ZBRA 4YTGA 1JDXA 2C6ZA 2JAJA 4YT9A 1H70A 2EWOA 2Q3UA 2DEYX 4N24A 2CI5A 4N2IA 2ACIA 4E4JA 2CI3A 3BPBA 2JDWA 1YNIA 4N20A 2CI1A 3I4AA 4JDWA 4N2NA 3I2EA 2DEWX 2DW5A
chains in the Genus database with same CATH topology
4DKTA 4X8CA 4YTBA 1LXYA 2JAIA 3HVMA 1JDWA 2CI7A 4N2LA 3H7CX 9JDWA 4N28A 4N26A 3RHYA 3H7KA 4N2KA 1XKNA 1WD9A 2DEXX 2ABRA 4N2DA 2A9GA 5HP5A 4N2AA 2JDXA 5AN9I 1G62A 3P8PA 4N2EA 2CI6A 1G61A 3B1UA 3APNA 5AK7A 4N2FA 2AAFA 3B1TA 5AK8A 8JDWA 4X8GA 7JDWA 1BWDA 1VKPA 5M3QA 3P8EA 4N2CA 3JDWA 6JDWA 2CMUA 4BOFA 4N2GA 4N2BA 1RXXA 2JERA 5JDWA 4N25A 3APMA 4N2MA 4N22A 1WD8A 2CI4A 4N2HA 1S9RA 1WDAA 1ZBRA 4YTGA 1JDXA 2C6ZA 2JAJA 4YT9A 1H70A 2EWOA 2Q3UA 2DEYX 4N24A 2CI5A 4N2IA 2ACIA 4E4JA 2CI3A 3BPBA 2JDWA 4N20A 2CI1A 3I4AA 4JDWA 4N2NA 3I2EA 2DEWX 2DW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DKT A;  4X8C A;  4YTB A;  1LXY A;  2JAI A;  3HVM A;  1JDW A;  2CI7 A;  4N2L A;  3H7C X;  9JDW A;  4N28 A;  4N26 A;  3RHY A;  3H7K A;  4N2K A;  1XKN A;  1WD9 A;  2DEX X;  2ABR A;  4N2D A;  2A9G A;  5HP5 A;  4N2A A;  2JDX A;  5AN9 I;  1G62 A;  3P8P A;  4N2E A;  2CI6 A;  1G61 A;  3B1U A;  3APN A;  5AK7 A;  4N2F A;  2AAF A;  3B1T A;  5AK8 A;  8JDW A;  4X8G A;  7JDW A;  1BWD A;  1VKP A;  5M3Q A;  3P8E A;  4N2C A;  3JDW A;  6JDW A;  2CMU A;  4BOF A;  4N2G A;  4N2B A;  1RXX A;  2JER A;  5JDW A;  4N25 A;  3APM A;  4N2M A;  4N22 A;  1WD8 A;  2CI4 A;  4N2H A;  1S9R A;  1WDA A;  1ZBR A;  4YTG A;  1JDX A;  2C6Z A;  2JAJ A;  4YT9 A;  1H70 A;  2EWO A;  2Q3U A;  2DEY X;  4N24 A;  2CI5 A;  4N2I A;  2ACI A;  4E4J A;  2CI3 A;  3BPB A;  2JDW A;  4N20 A;  2CI1 A;  3I4A A;  4JDW A;  4N2N A;  3I2E A;  2DEW X;  2DW5 A; 
#chains in the Genus database with same CATH topology
 4DKT A;  4X8C A;  4YTB A;  1LXY A;  2JAI A;  3HVM A;  1JDW A;  2CI7 A;  4N2L A;  3H7C X;  9JDW A;  4N28 A;  4N26 A;  3RHY A;  3H7K A;  4N2K A;  1XKN A;  1WD9 A;  2DEX X;  2ABR A;  4N2D A;  2A9G A;  5HP5 A;  4N2A A;  2JDX A;  1YNH A;  5AN9 I;  1G62 A;  3P8P A;  4N2E A;  2CI6 A;  1G61 A;  3B1U A;  3APN A;  5AK7 A;  4N2F A;  2AAF A;  3B1T A;  5AK8 A;  8JDW A;  4X8G A;  7JDW A;  1YNF A;  1BWD A;  1VKP A;  5M3Q A;  3P8E A;  4N2C A;  3JDW A;  6JDW A;  2CMU A;  4BOF A;  4N2G A;  4N2B A;  1RXX A;  2JER A;  5JDW A;  4N25 A;  3APM A;  4N2M A;  4N22 A;  1WD8 A;  2CI4 A;  4N2H A;  1S9R A;  1WDA A;  1ZBR A;  4YTG A;  1JDX A;  2C6Z A;  2JAJ A;  4YT9 A;  1H70 A;  2EWO A;  2Q3U A;  2DEY X;  4N24 A;  2CI5 A;  4N2I A;  2ACI A;  4E4J A;  2CI3 A;  3BPB A;  2JDW A;  1YNI A;  4N20 A;  2CI1 A;  3I4A A;  4JDW A;  4N2N A;  3I2E A;  2DEW X;  2DW5 A; 
#chains in the Genus database with same CATH homology
 4DKT A;  4X8C A;  4YTB A;  1LXY A;  2JAI A;  3HVM A;  1JDW A;  2CI7 A;  4N2L A;  3H7C X;  9JDW A;  4N28 A;  4N26 A;  3RHY A;  3H7K A;  4N2K A;  1XKN A;  1WD9 A;  2DEX X;  2ABR A;  4N2D A;  2A9G A;  5HP5 A;  4N2A A;  2JDX A;  5AN9 I;  1G62 A;  3P8P A;  4N2E A;  2CI6 A;  1G61 A;  3B1U A;  3APN A;  5AK7 A;  4N2F A;  2AAF A;  3B1T A;  5AK8 A;  8JDW A;  4X8G A;  7JDW A;  1BWD A;  1VKP A;  5M3Q A;  3P8E A;  4N2C A;  3JDW A;  6JDW A;  2CMU A;  4BOF A;  4N2G A;  4N2B A;  1RXX A;  2JER A;  5JDW A;  4N25 A;  3APM A;  4N2M A;  4N22 A;  1WD8 A;  2CI4 A;  4N2H A;  1S9R A;  1WDA A;  1ZBR A;  4YTG A;  1JDX A;  2C6Z A;  2JAJ A;  4YT9 A;  1H70 A;  2EWO A;  2Q3U A;  2DEY X;  4N24 A;  2CI5 A;  4N2I A;  2ACI A;  4E4J A;  2CI3 A;  3BPB A;  2JDW A;  4N20 A;  2CI1 A;  3I4A A;  4JDW A;  4N2N A;  3I2E A;  2DEW X;  2DW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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