2CI4A

Crystal structure of dimethylarginine dimethylaminohydrolase i crystal form ii
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
273
structure length
273
Chain Sequence
TFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 94
structure length 273
sequence length 273
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2ci4A00
4N26A 1JDWA 4N2FA 3JDWA 7JDWA 5JDWA 3I4AA 2DEXX 2A9GA 4N2BA 2DEYX 2JDXA 2AAFA 4BOFA 1LXYA 4YT9A 4N24A 4N25A 2C6ZA 2Q3UA 5AK8A 4YTGA 1JDXA 2CI1A 2CI4A 4N28A 3BPBA 2CI3A 1G62A 2JERA 3H7KA 4N2DA 2CMUA 4N20A 4N2LA 2JDWA 5HP5A 1VKPA 4X8GA 4X8CA 5M3QA 1ZBRA 3B1UA 4JDWA 9JDWA 4E4JA 1BWDA 3P8EA 1S9RA 1H70A 2ABRA 5AK7A 2DEWX 1WD9A 1XKNA 4N2AA 4N2NA 2CI5A 8JDWA 3H7CX 2EWOA 1G61A 3RHYA 3APMA 2JAJA 4N2EA 2DW5A 4N2CA 1RXXA 5AN9I 3I2EA 3B1TA 6JDWA 1WDAA 4N2HA 3APNA 3P8PA 4N2IA 4N2MA 2ACIA 4N22A 3HVMA 4YTBA 2JAIA 4DKTA 2CI6A 4N2KA 1WD8A 2CI7A 4N2GA
chains in the Genus database with same CATH superfamily
4N26A 1JDWA 4N2FA 3JDWA 7JDWA 5JDWA 3I4AA 2DEXX 2A9GA 4N2BA 2DEYX 2JDXA 2AAFA 4BOFA 1LXYA 4YT9A 4N24A 4N25A 2C6ZA 2Q3UA 5AK8A 4YTGA 1JDXA 2CI1A 2CI4A 4N28A 3BPBA 2CI3A 1G62A 2JERA 3H7KA 4N2DA 2CMUA 4N20A 4N2LA 2JDWA 5HP5A 1VKPA 4X8GA 4X8CA 5M3QA 1ZBRA 3B1UA 4JDWA 1YNHA 9JDWA 4E4JA 1BWDA 3P8EA 1S9RA 1H70A 2ABRA 5AK7A 2DEWX 1YNFA 1WD9A 1XKNA 4N2AA 4N2NA 2CI5A 8JDWA 3H7CX 2EWOA 1G61A 3RHYA 3APMA 2JAJA 4N2EA 2DW5A 4N2CA 1RXXA 5AN9I 3I2EA 3B1TA 6JDWA 1WDAA 4N2HA 3APNA 3P8PA 4N2IA 4N2MA 1YNIA 2ACIA 4N22A 3HVMA 4YTBA 2JAIA 4DKTA 2CI6A 4N2KA 1WD8A 2CI7A 4N2GA
chains in the Genus database with same CATH topology
4N26A 1JDWA 4N2FA 3JDWA 7JDWA 5JDWA 3I4AA 2DEXX 2A9GA 4N2BA 2DEYX 2JDXA 2AAFA 4BOFA 1LXYA 4YT9A 4N24A 4N25A 2C6ZA 2Q3UA 5AK8A 4YTGA 1JDXA 2CI1A 2CI4A 4N28A 3BPBA 2CI3A 1G62A 2JERA 3H7KA 4N2DA 2CMUA 4N20A 4N2LA 2JDWA 5HP5A 1VKPA 4X8GA 4X8CA 5M3QA 1ZBRA 3B1UA 4JDWA 9JDWA 4E4JA 1BWDA 3P8EA 1S9RA 1H70A 2ABRA 5AK7A 2DEWX 1WD9A 1XKNA 4N2AA 4N2NA 2CI5A 8JDWA 3H7CX 2EWOA 1G61A 3RHYA 3APMA 2JAJA 4N2EA 2DW5A 4N2CA 1RXXA 5AN9I 3I2EA 3B1TA 6JDWA 1WDAA 4N2HA 3APNA 3P8PA 4N2IA 4N2MA 2ACIA 4N22A 3HVMA 4YTBA 2JAIA 4DKTA 2CI6A 4N2KA 1WD8A 2CI7A 4N2GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N26 A;  1JDW A;  4N2F A;  3JDW A;  7JDW A;  5JDW A;  3I4A A;  2DEX X;  2A9G A;  4N2B A;  2DEY X;  2JDX A;  2AAF A;  4BOF A;  1LXY A;  4YT9 A;  4N24 A;  4N25 A;  2C6Z A;  2Q3U A;  5AK8 A;  4YTG A;  1JDX A;  2CI1 A;  2CI4 A;  4N28 A;  3BPB A;  2CI3 A;  1G62 A;  2JER A;  3H7K A;  4N2D A;  2CMU A;  4N20 A;  4N2L A;  2JDW A;  5HP5 A;  1VKP A;  4X8G A;  4X8C A;  5M3Q A;  1ZBR A;  3B1U A;  4JDW A;  9JDW A;  4E4J A;  1BWD A;  3P8E A;  1S9R A;  1H70 A;  2ABR A;  5AK7 A;  2DEW X;  1WD9 A;  1XKN A;  4N2A A;  4N2N A;  2CI5 A;  8JDW A;  3H7C X;  2EWO A;  1G61 A;  3RHY A;  3APM A;  2JAJ A;  4N2E A;  2DW5 A;  4N2C A;  1RXX A;  5AN9 I;  3I2E A;  3B1T A;  6JDW A;  1WDA A;  4N2H A;  3APN A;  3P8P A;  4N2I A;  4N2M A;  2ACI A;  4N22 A;  3HVM A;  4YTB A;  2JAI A;  4DKT A;  2CI6 A;  4N2K A;  1WD8 A;  2CI7 A;  4N2G A; 
#chains in the Genus database with same CATH topology
 4N26 A;  1JDW A;  4N2F A;  3JDW A;  7JDW A;  5JDW A;  3I4A A;  2DEX X;  2A9G A;  4N2B A;  2DEY X;  2JDX A;  2AAF A;  4BOF A;  1LXY A;  4YT9 A;  4N24 A;  4N25 A;  2C6Z A;  2Q3U A;  5AK8 A;  4YTG A;  1JDX A;  2CI1 A;  2CI4 A;  4N28 A;  3BPB A;  2CI3 A;  1G62 A;  2JER A;  3H7K A;  4N2D A;  2CMU A;  4N20 A;  4N2L A;  2JDW A;  5HP5 A;  1VKP A;  4X8G A;  4X8C A;  5M3Q A;  1ZBR A;  3B1U A;  4JDW A;  1YNH A;  9JDW A;  4E4J A;  1BWD A;  3P8E A;  1S9R A;  1H70 A;  2ABR A;  5AK7 A;  2DEW X;  1YNF A;  1WD9 A;  1XKN A;  4N2A A;  4N2N A;  2CI5 A;  8JDW A;  3H7C X;  2EWO A;  1G61 A;  3RHY A;  3APM A;  2JAJ A;  4N2E A;  2DW5 A;  4N2C A;  1RXX A;  5AN9 I;  3I2E A;  3B1T A;  6JDW A;  1WDA A;  4N2H A;  3APN A;  3P8P A;  4N2I A;  4N2M A;  1YNI A;  2ACI A;  4N22 A;  3HVM A;  4YTB A;  2JAI A;  4DKT A;  2CI6 A;  4N2K A;  1WD8 A;  2CI7 A;  4N2G A; 
#chains in the Genus database with same CATH homology
 4N26 A;  1JDW A;  4N2F A;  3JDW A;  7JDW A;  5JDW A;  3I4A A;  2DEX X;  2A9G A;  4N2B A;  2DEY X;  2JDX A;  2AAF A;  4BOF A;  1LXY A;  4YT9 A;  4N24 A;  4N25 A;  2C6Z A;  2Q3U A;  5AK8 A;  4YTG A;  1JDX A;  2CI1 A;  2CI4 A;  4N28 A;  3BPB A;  2CI3 A;  1G62 A;  2JER A;  3H7K A;  4N2D A;  2CMU A;  4N20 A;  4N2L A;  2JDW A;  5HP5 A;  1VKP A;  4X8G A;  4X8C A;  5M3Q A;  1ZBR A;  3B1U A;  4JDW A;  9JDW A;  4E4J A;  1BWD A;  3P8E A;  1S9R A;  1H70 A;  2ABR A;  5AK7 A;  2DEW X;  1WD9 A;  1XKN A;  4N2A A;  4N2N A;  2CI5 A;  8JDW A;  3H7C X;  2EWO A;  1G61 A;  3RHY A;  3APM A;  2JAJ A;  4N2E A;  2DW5 A;  4N2C A;  1RXX A;  5AN9 I;  3I2E A;  3B1T A;  6JDW A;  1WDA A;  4N2H A;  3APN A;  3P8P A;  4N2I A;  4N2M A;  2ACI A;  4N22 A;  3HVM A;  4YTB A;  2JAI A;  4DKT A;  2CI6 A;  4N2K A;  1WD8 A;  2CI7 A;  4N2G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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