2CI5A

Crystal structure of dimethylarginine dimethylaminohydrolase i in complex with l-homocysteine
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
272
structure length
272
Chain Sequence
FGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inbitors
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 89
structure length 272
sequence length 272
chains with identical sequence B
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2ci5A00
3BPBA 2CI4A 2JDXA 4N2DA 2CI7A 1JDXA 4JDWA 4YTBA 4N2GA 3RHYA 1VKPA 2CI6A 4N22A 2CI3A 2DEWX 5AK7A 4N2LA 3P8EA 4N2KA 2EWOA 3I4AA 8JDWA 4YTGA 4X8GA 2JAIA 3HVMA 3H7CX 5HP5A 4N2MA 1WD9A 2ABRA 5M3QA 2AAFA 2DW5A 3APMA 1G61A 2CMUA 1RXXA 3I2EA 4N2FA 2C6ZA 4N2HA 1H70A 1S9RA 4N20A 9JDWA 4N28A 1LXYA 4DKTA 4N2NA 3JDWA 6JDWA 1G62A 4N2AA 2CI5A 1ZBRA 2Q3UA 3B1TA 2DEYX 3B1UA 1XKNA 5JDWA 2JDWA 3APNA 4N25A 2DEXX 4N2CA 5AN9I 7JDWA 2ACIA 5AK8A 3P8PA 3H7KA 1JDWA 4N2IA 4X8CA 4N24A 4N26A 4N2EA 4YT9A 2CI1A 2A9GA 1WD8A 4BOFA 1WDAA 4E4JA 4N2BA 2JERA 2JAJA 1BWDA
chains in the Genus database with same CATH superfamily
3BPBA 2CI4A 2JDXA 4N2DA 2CI7A 1JDXA 4JDWA 4YTBA 4N2GA 3RHYA 1VKPA 2CI6A 4N22A 2CI3A 2DEWX 5AK7A 4N2LA 3P8EA 4N2KA 2EWOA 3I4AA 8JDWA 4YTGA 4X8GA 2JAIA 3HVMA 3H7CX 5HP5A 4N2MA 1WD9A 2ABRA 5M3QA 2AAFA 2DW5A 3APMA 1G61A 1YNIA 2CMUA 1RXXA 3I2EA 4N2FA 2C6ZA 4N2HA 1H70A 1S9RA 4N20A 9JDWA 4N28A 1LXYA 4DKTA 4N2NA 3JDWA 1YNHA 6JDWA 1G62A 1YNFA 4N2AA 2CI5A 1ZBRA 2Q3UA 3B1TA 2DEYX 3B1UA 1XKNA 5JDWA 2JDWA 3APNA 4N25A 2DEXX 4N2CA 5AN9I 7JDWA 2ACIA 5AK8A 3P8PA 3H7KA 1JDWA 4N2IA 4X8CA 4N24A 4N26A 4N2EA 4YT9A 2CI1A 2A9GA 1WD8A 4BOFA 1WDAA 4E4JA 4N2BA 2JERA 2JAJA 1BWDA
chains in the Genus database with same CATH topology
3BPBA 2CI4A 2JDXA 4N2DA 2CI7A 1JDXA 4JDWA 4YTBA 4N2GA 3RHYA 1VKPA 2CI6A 4N22A 2CI3A 2DEWX 5AK7A 4N2LA 3P8EA 4N2KA 2EWOA 3I4AA 8JDWA 4YTGA 4X8GA 2JAIA 3HVMA 3H7CX 5HP5A 4N2MA 1WD9A 2ABRA 5M3QA 2AAFA 2DW5A 3APMA 1G61A 2CMUA 1RXXA 3I2EA 4N2FA 2C6ZA 4N2HA 1H70A 1S9RA 4N20A 9JDWA 4N28A 1LXYA 4DKTA 4N2NA 3JDWA 6JDWA 1G62A 4N2AA 2CI5A 1ZBRA 2Q3UA 3B1TA 2DEYX 3B1UA 1XKNA 5JDWA 2JDWA 3APNA 4N25A 2DEXX 4N2CA 5AN9I 7JDWA 2ACIA 5AK8A 3P8PA 3H7KA 1JDWA 4N2IA 4X8CA 4N24A 4N26A 4N2EA 4YT9A 2CI1A 2A9GA 1WD8A 4BOFA 1WDAA 4E4JA 4N2BA 2JERA 2JAJA 1BWDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BPB A;  2CI4 A;  2JDX A;  4N2D A;  2CI7 A;  1JDX A;  4JDW A;  4YTB A;  4N2G A;  3RHY A;  1VKP A;  2CI6 A;  4N22 A;  2CI3 A;  2DEW X;  5AK7 A;  4N2L A;  3P8E A;  4N2K A;  2EWO A;  3I4A A;  8JDW A;  4YTG A;  4X8G A;  2JAI A;  3HVM A;  3H7C X;  5HP5 A;  4N2M A;  1WD9 A;  2ABR A;  5M3Q A;  2AAF A;  2DW5 A;  3APM A;  1G61 A;  2CMU A;  1RXX A;  3I2E A;  4N2F A;  2C6Z A;  4N2H A;  1H70 A;  1S9R A;  4N20 A;  9JDW A;  4N28 A;  1LXY A;  4DKT A;  4N2N A;  3JDW A;  6JDW A;  1G62 A;  4N2A A;  2CI5 A;  1ZBR A;  2Q3U A;  3B1T A;  2DEY X;  3B1U A;  1XKN A;  5JDW A;  2JDW A;  3APN A;  4N25 A;  2DEX X;  4N2C A;  5AN9 I;  7JDW A;  2ACI A;  5AK8 A;  3P8P A;  3H7K A;  1JDW A;  4N2I A;  4X8C A;  4N24 A;  4N26 A;  4N2E A;  4YT9 A;  2CI1 A;  2A9G A;  1WD8 A;  4BOF A;  1WDA A;  4E4J A;  4N2B A;  2JER A;  2JAJ A;  1BWD A; 
#chains in the Genus database with same CATH topology
 3BPB A;  2CI4 A;  2JDX A;  4N2D A;  2CI7 A;  1JDX A;  4JDW A;  4YTB A;  4N2G A;  3RHY A;  1VKP A;  2CI6 A;  4N22 A;  2CI3 A;  2DEW X;  5AK7 A;  4N2L A;  3P8E A;  4N2K A;  2EWO A;  3I4A A;  8JDW A;  4YTG A;  4X8G A;  2JAI A;  3HVM A;  3H7C X;  5HP5 A;  4N2M A;  1WD9 A;  2ABR A;  5M3Q A;  2AAF A;  2DW5 A;  3APM A;  1G61 A;  1YNI A;  2CMU A;  1RXX A;  3I2E A;  4N2F A;  2C6Z A;  4N2H A;  1H70 A;  1S9R A;  4N20 A;  9JDW A;  4N28 A;  1LXY A;  4DKT A;  4N2N A;  3JDW A;  1YNH A;  6JDW A;  1G62 A;  1YNF A;  4N2A A;  2CI5 A;  1ZBR A;  2Q3U A;  3B1T A;  2DEY X;  3B1U A;  1XKN A;  5JDW A;  2JDW A;  3APN A;  4N25 A;  2DEX X;  4N2C A;  5AN9 I;  7JDW A;  2ACI A;  5AK8 A;  3P8P A;  3H7K A;  1JDW A;  4N2I A;  4X8C A;  4N24 A;  4N26 A;  4N2E A;  4YT9 A;  2CI1 A;  2A9G A;  1WD8 A;  4BOF A;  1WDA A;  4E4J A;  4N2B A;  2JER A;  2JAJ A;  1BWD A; 
#chains in the Genus database with same CATH homology
 3BPB A;  2CI4 A;  2JDX A;  4N2D A;  2CI7 A;  1JDX A;  4JDW A;  4YTB A;  4N2G A;  3RHY A;  1VKP A;  2CI6 A;  4N22 A;  2CI3 A;  2DEW X;  5AK7 A;  4N2L A;  3P8E A;  4N2K A;  2EWO A;  3I4A A;  8JDW A;  4YTG A;  4X8G A;  2JAI A;  3HVM A;  3H7C X;  5HP5 A;  4N2M A;  1WD9 A;  2ABR A;  5M3Q A;  2AAF A;  2DW5 A;  3APM A;  1G61 A;  2CMU A;  1RXX A;  3I2E A;  4N2F A;  2C6Z A;  4N2H A;  1H70 A;  1S9R A;  4N20 A;  9JDW A;  4N28 A;  1LXY A;  4DKT A;  4N2N A;  3JDW A;  6JDW A;  1G62 A;  4N2A A;  2CI5 A;  1ZBR A;  2Q3U A;  3B1T A;  2DEY X;  3B1U A;  1XKN A;  5JDW A;  2JDW A;  3APN A;  4N25 A;  2DEX X;  4N2C A;  5AN9 I;  7JDW A;  2ACI A;  5AK8 A;  3P8P A;  3H7K A;  1JDW A;  4N2I A;  4X8C A;  4N24 A;  4N26 A;  4N2E A;  4YT9 A;  2CI1 A;  2A9G A;  1WD8 A;  4BOF A;  1WDA A;  4E4J A;  4N2B A;  2JER A;  2JAJ A;  1BWD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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