2JDWA

Crystal structure and mechanism of l-arginine: glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords L-ARGININE\:GLYCINE AMIDINOTRANSFERASE
total genus 121
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1997-01-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2jdwA00
2CI1A 1S9RA 4N2AA 2JAIA 1H70A 2A9GA 4N2HA 2ACIA 9JDWA 2CI5A 4DKTA 2JDWA 2DEXX 2ABRA 1BWDA 5JDWA 7JDWA 3B1UA 3I2EA 4BOFA 3JDWA 4N2GA 4YTBA 2C6ZA 1WDAA 3I4AA 3APNA 2EWOA 4YTGA 4N22A 4N2NA 5AK7A 1RXXA 2CI6A 4N2IA 1JDWA 4YT9A 1LXYA 3APMA 4N26A 4X8CA 2DEYX 3BPBA 1WD9A 4N28A 3B1TA 2CI4A 1ZBRA 2Q3UA 1WD8A 3HVMA 4N2MA 1JDXA 4N2CA 4N20A 2CI3A 1G61A 3P8PA 1XKNA 4X8GA 2JERA 2DW5A 3P8EA 4N2FA 5M3QA 2CI7A 2DEWX 4N2LA 4N25A 4N2EA 5AK8A 2CMUA 3H7KA 1G62A 2JDXA 5AN9I 5HP5A 4JDWA 4N2DA 4N2KA 8JDWA 4E4JA 2JAJA 2AAFA 4N24A 4N2BA 6JDWA 3H7CX 1VKPA 3RHYA
chains in the Genus database with same CATH superfamily
2CI1A 1S9RA 4N2AA 2JAIA 2A9GA 4N2HA 2ACIA 9JDWA 2CI5A 4DKTA 2JDWA 1YNFA 2DEXX 2ABRA 1BWDA 5JDWA 7JDWA 3B1UA 3I2EA 4BOFA 3JDWA 4N2GA 4YTBA 2C6ZA 1WDAA 3RHYA 3I4AA 3APNA 2EWOA 4YTGA 4N22A 4N2NA 5AK7A 1RXXA 2CI6A 4N2IA 1JDWA 4YT9A 1LXYA 3APMA 4N26A 4X8CA 2DEYX 3BPBA 1WD9A 4N28A 3B1TA 2CI4A 1ZBRA 2Q3UA 1WD8A 3HVMA 1YNHA 4N2MA 1JDXA 4N2CA 4N20A 2CI3A 1G61A 3P8PA 1XKNA 4X8GA 2JERA 2DW5A 3P8EA 4N2FA 5M3QA 2CI7A 2DEWX 4N2LA 4N25A 4N2EA 5AK8A 2CMUA 3H7KA 1G62A 2JDXA 5AN9I 5HP5A 4JDWA 4N2DA 4N2KA 8JDWA 4E4JA 2JAJA 2AAFA 4N24A 4N2BA 1YNIA 6JDWA 3H7CX 1VKPA 1H70A
chains in the Genus database with same CATH topology
2CI1A 1S9RA 4N2AA 2JAIA 1H70A 2A9GA 4N2HA 2ACIA 9JDWA 2CI5A 4DKTA 2JDWA 2DEXX 2ABRA 1BWDA 5JDWA 7JDWA 3B1UA 3I2EA 4BOFA 3JDWA 4N2GA 4YTBA 2C6ZA 1WDAA 3I4AA 3APNA 2EWOA 4YTGA 4N22A 4N2NA 5AK7A 1RXXA 2CI6A 4N2IA 1JDWA 4YT9A 1LXYA 3APMA 4N26A 4X8CA 2DEYX 3BPBA 1WD9A 4N28A 3B1TA 2CI4A 1ZBRA 2Q3UA 1WD8A 3HVMA 4N2MA 1JDXA 4N2CA 4N20A 2CI3A 1G61A 3P8PA 1XKNA 4X8GA 2JERA 2DW5A 3P8EA 4N2FA 5M3QA 2CI7A 2DEWX 4N2LA 4N25A 4N2EA 5AK8A 2CMUA 3H7KA 1G62A 2JDXA 5AN9I 5HP5A 4JDWA 4N2DA 4N2KA 8JDWA 4E4JA 2JAJA 2AAFA 4N24A 4N2BA 6JDWA 3H7CX 1VKPA 3RHYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CI1 A;  1S9R A;  4N2A A;  2JAI A;  1H70 A;  2A9G A;  4N2H A;  2ACI A;  9JDW A;  2CI5 A;  4DKT A;  2JDW A;  2DEX X;  2ABR A;  1BWD A;  5JDW A;  7JDW A;  3B1U A;  3I2E A;  4BOF A;  3JDW A;  4N2G A;  4YTB A;  2C6Z A;  1WDA A;  3I4A A;  3APN A;  2EWO A;  4YTG A;  4N22 A;  4N2N A;  5AK7 A;  1RXX A;  2CI6 A;  4N2I A;  1JDW A;  4YT9 A;  1LXY A;  3APM A;  4N26 A;  4X8C A;  2DEY X;  3BPB A;  1WD9 A;  4N28 A;  3B1T A;  2CI4 A;  1ZBR A;  2Q3U A;  1WD8 A;  3HVM A;  4N2M A;  1JDX A;  4N2C A;  4N20 A;  2CI3 A;  1G61 A;  3P8P A;  1XKN A;  4X8G A;  2JER A;  2DW5 A;  3P8E A;  4N2F A;  5M3Q A;  2CI7 A;  2DEW X;  4N2L A;  4N25 A;  4N2E A;  5AK8 A;  2CMU A;  3H7K A;  1G62 A;  2JDX A;  5AN9 I;  5HP5 A;  4JDW A;  4N2D A;  4N2K A;  8JDW A;  4E4J A;  2JAJ A;  2AAF A;  4N24 A;  4N2B A;  6JDW A;  3H7C X;  1VKP A;  3RHY A; 
#chains in the Genus database with same CATH topology
 2CI1 A;  1S9R A;  4N2A A;  2JAI A;  2A9G A;  4N2H A;  2ACI A;  9JDW A;  2CI5 A;  4DKT A;  2JDW A;  1YNF A;  2DEX X;  2ABR A;  1BWD A;  5JDW A;  7JDW A;  3B1U A;  3I2E A;  4BOF A;  3JDW A;  4N2G A;  4YTB A;  2C6Z A;  1WDA A;  3RHY A;  3I4A A;  3APN A;  2EWO A;  4YTG A;  4N22 A;  4N2N A;  5AK7 A;  1RXX A;  2CI6 A;  4N2I A;  1JDW A;  4YT9 A;  1LXY A;  3APM A;  4N26 A;  4X8C A;  2DEY X;  3BPB A;  1WD9 A;  4N28 A;  3B1T A;  2CI4 A;  1ZBR A;  2Q3U A;  1WD8 A;  3HVM A;  1YNH A;  4N2M A;  1JDX A;  4N2C A;  4N20 A;  2CI3 A;  1G61 A;  3P8P A;  1XKN A;  4X8G A;  2JER A;  2DW5 A;  3P8E A;  4N2F A;  5M3Q A;  2CI7 A;  2DEW X;  4N2L A;  4N25 A;  4N2E A;  5AK8 A;  2CMU A;  3H7K A;  1G62 A;  2JDX A;  5AN9 I;  5HP5 A;  4JDW A;  4N2D A;  4N2K A;  8JDW A;  4E4J A;  2JAJ A;  2AAF A;  4N24 A;  4N2B A;  1YNI A;  6JDW A;  3H7C X;  1VKP A;  1H70 A; 
#chains in the Genus database with same CATH homology
 2CI1 A;  1S9R A;  4N2A A;  2JAI A;  1H70 A;  2A9G A;  4N2H A;  2ACI A;  9JDW A;  2CI5 A;  4DKT A;  2JDW A;  2DEX X;  2ABR A;  1BWD A;  5JDW A;  7JDW A;  3B1U A;  3I2E A;  4BOF A;  3JDW A;  4N2G A;  4YTB A;  2C6Z A;  1WDA A;  3I4A A;  3APN A;  2EWO A;  4YTG A;  4N22 A;  4N2N A;  5AK7 A;  1RXX A;  2CI6 A;  4N2I A;  1JDW A;  4YT9 A;  1LXY A;  3APM A;  4N26 A;  4X8C A;  2DEY X;  3BPB A;  1WD9 A;  4N28 A;  3B1T A;  2CI4 A;  1ZBR A;  2Q3U A;  1WD8 A;  3HVM A;  4N2M A;  1JDX A;  4N2C A;  4N20 A;  2CI3 A;  1G61 A;  3P8P A;  1XKN A;  4X8G A;  2JER A;  2DW5 A;  3P8E A;  4N2F A;  5M3Q A;  2CI7 A;  2DEW X;  4N2L A;  4N25 A;  4N2E A;  5AK8 A;  2CMU A;  3H7K A;  1G62 A;  2JDX A;  5AN9 I;  5HP5 A;  4JDW A;  4N2D A;  4N2K A;  8JDW A;  4E4J A;  2JAJ A;  2AAF A;  4N24 A;  4N2B A;  6JDW A;  3H7C X;  1VKP A;  3RHY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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