2C6ZA

Crystal structure of dimethylarginine dimethylaminohydrolase i in complex with citrulline
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
273
structure length
273
Chain Sequence
TFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inbitors
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 102
structure length 273
sequence length 273
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2005-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2c6zA00
3RHYA 4DKTA 3I2EA 3B1TA 5HP5A 2CI1A 2C6ZA 2DEXX 3H7CX 2JDWA 6JDWA 4N2DA 2JERA 3HVMA 3P8PA 4N2EA 5AK8A 4N2GA 2JAIA 4X8CA 4N2AA 2CI5A 5AK7A 1JDXA 1LXYA 4E4JA 2A9GA 4N2NA 2CI7A 2ABRA 2DW5A 4N2KA 1RXXA 4N25A 1WDAA 1XKNA 1WD8A 3APNA 4JDWA 7JDWA 4YT9A 2ACIA 3JDWA 3P8EA 4N2BA 4YTBA 2EWOA 3APMA 4N2MA 2Q3UA 1ZBRA 4N2LA 8JDWA 3BPBA 3I4AA 9JDWA 2JDXA 4N24A 2DEWX 4N26A 4BOFA 1G61A 1BWDA 4N2HA 5M3QA 2DEYX 1WD9A 1JDWA 1S9RA 1VKPA 4N2CA 1G62A 5JDWA 2CI4A 4N2IA 4X8GA 4N2FA 2CMUA 3H7KA 2CI6A 5AN9I 1H70A 4YTGA 2JAJA 4N22A 4N20A 2CI3A 3B1UA 4N28A 2AAFA
chains in the Genus database with same CATH superfamily
1YNFA 3RHYA 4DKTA 3I2EA 3B1TA 5HP5A 2CI1A 2C6ZA 2DEXX 3H7CX 2JDWA 6JDWA 4N2DA 2JERA 3HVMA 3P8PA 4N2EA 5AK8A 4N2GA 2JAIA 4X8CA 4N2AA 2CI5A 5AK7A 1JDXA 1LXYA 4E4JA 2A9GA 4N2NA 2CI7A 2ABRA 2DW5A 4N2KA 1RXXA 4N25A 1YNHA 1WDAA 1XKNA 1WD8A 3APNA 4JDWA 7JDWA 4YT9A 2ACIA 3JDWA 3P8EA 4N2BA 4YTBA 2EWOA 3APMA 4N2MA 2Q3UA 1ZBRA 4N2LA 8JDWA 3BPBA 3I4AA 9JDWA 2JDXA 4N24A 2DEWX 4N26A 4BOFA 1G61A 1BWDA 4N2HA 5M3QA 2DEYX 1WD9A 1YNIA 1JDWA 1S9RA 1VKPA 4N2CA 1G62A 5JDWA 2CI4A 4N2IA 4X8GA 4N2FA 2CMUA 3H7KA 2CI6A 5AN9I 1H70A 4YTGA 2JAJA 4N22A 4N20A 2CI3A 3B1UA 4N28A 2AAFA
chains in the Genus database with same CATH topology
3RHYA 4DKTA 3I2EA 3B1TA 5HP5A 2CI1A 2C6ZA 2DEXX 3H7CX 2JDWA 6JDWA 4N2DA 2JERA 3HVMA 3P8PA 4N2EA 5AK8A 4N2GA 2JAIA 4X8CA 4N2AA 2CI5A 5AK7A 1JDXA 1LXYA 4E4JA 2A9GA 4N2NA 2CI7A 2ABRA 2DW5A 4N2KA 1RXXA 4N25A 1WDAA 1XKNA 1WD8A 3APNA 4JDWA 7JDWA 4YT9A 2ACIA 3JDWA 3P8EA 4N2BA 4YTBA 2EWOA 3APMA 4N2MA 2Q3UA 1ZBRA 4N2LA 8JDWA 3BPBA 3I4AA 9JDWA 2JDXA 4N24A 2DEWX 4N26A 4BOFA 1G61A 1BWDA 4N2HA 5M3QA 2DEYX 1WD9A 1JDWA 1S9RA 1VKPA 4N2CA 1G62A 5JDWA 2CI4A 4N2IA 4X8GA 4N2FA 2CMUA 3H7KA 2CI6A 5AN9I 1H70A 4YTGA 2JAJA 4N22A 4N20A 2CI3A 3B1UA 4N28A 2AAFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RHY A;  4DKT A;  3I2E A;  3B1T A;  5HP5 A;  2CI1 A;  2C6Z A;  2DEX X;  3H7C X;  2JDW A;  6JDW A;  4N2D A;  2JER A;  3HVM A;  3P8P A;  4N2E A;  5AK8 A;  4N2G A;  2JAI A;  4X8C A;  4N2A A;  2CI5 A;  5AK7 A;  1JDX A;  1LXY A;  4E4J A;  2A9G A;  4N2N A;  2CI7 A;  2ABR A;  2DW5 A;  4N2K A;  1RXX A;  4N25 A;  1WDA A;  1XKN A;  1WD8 A;  3APN A;  4JDW A;  7JDW A;  4YT9 A;  2ACI A;  3JDW A;  3P8E A;  4N2B A;  4YTB A;  2EWO A;  3APM A;  4N2M A;  2Q3U A;  1ZBR A;  4N2L A;  8JDW A;  3BPB A;  3I4A A;  9JDW A;  2JDX A;  4N24 A;  2DEW X;  4N26 A;  4BOF A;  1G61 A;  1BWD A;  4N2H A;  5M3Q A;  2DEY X;  1WD9 A;  1JDW A;  1S9R A;  1VKP A;  4N2C A;  1G62 A;  5JDW A;  2CI4 A;  4N2I A;  4X8G A;  4N2F A;  2CMU A;  3H7K A;  2CI6 A;  5AN9 I;  1H70 A;  4YTG A;  2JAJ A;  4N22 A;  4N20 A;  2CI3 A;  3B1U A;  4N28 A;  2AAF A; 
#chains in the Genus database with same CATH topology
 1YNF A;  3RHY A;  4DKT A;  3I2E A;  3B1T A;  5HP5 A;  2CI1 A;  2C6Z A;  2DEX X;  3H7C X;  2JDW A;  6JDW A;  4N2D A;  2JER A;  3HVM A;  3P8P A;  4N2E A;  5AK8 A;  4N2G A;  2JAI A;  4X8C A;  4N2A A;  2CI5 A;  5AK7 A;  1JDX A;  1LXY A;  4E4J A;  2A9G A;  4N2N A;  2CI7 A;  2ABR A;  2DW5 A;  4N2K A;  1RXX A;  4N25 A;  1YNH A;  1WDA A;  1XKN A;  1WD8 A;  3APN A;  4JDW A;  7JDW A;  4YT9 A;  2ACI A;  3JDW A;  3P8E A;  4N2B A;  4YTB A;  2EWO A;  3APM A;  4N2M A;  2Q3U A;  1ZBR A;  4N2L A;  8JDW A;  3BPB A;  3I4A A;  9JDW A;  2JDX A;  4N24 A;  2DEW X;  4N26 A;  4BOF A;  1G61 A;  1BWD A;  4N2H A;  5M3Q A;  2DEY X;  1WD9 A;  1YNI A;  1JDW A;  1S9R A;  1VKP A;  4N2C A;  1G62 A;  5JDW A;  2CI4 A;  4N2I A;  4X8G A;  4N2F A;  2CMU A;  3H7K A;  2CI6 A;  5AN9 I;  1H70 A;  4YTG A;  2JAJ A;  4N22 A;  4N20 A;  2CI3 A;  3B1U A;  4N28 A;  2AAF A; 
#chains in the Genus database with same CATH homology
 3RHY A;  4DKT A;  3I2E A;  3B1T A;  5HP5 A;  2CI1 A;  2C6Z A;  2DEX X;  3H7C X;  2JDW A;  6JDW A;  4N2D A;  2JER A;  3HVM A;  3P8P A;  4N2E A;  5AK8 A;  4N2G A;  2JAI A;  4X8C A;  4N2A A;  2CI5 A;  5AK7 A;  1JDX A;  1LXY A;  4E4J A;  2A9G A;  4N2N A;  2CI7 A;  2ABR A;  2DW5 A;  4N2K A;  1RXX A;  4N25 A;  1WDA A;  1XKN A;  1WD8 A;  3APN A;  4JDW A;  7JDW A;  4YT9 A;  2ACI A;  3JDW A;  3P8E A;  4N2B A;  4YTB A;  2EWO A;  3APM A;  4N2M A;  2Q3U A;  1ZBR A;  4N2L A;  8JDW A;  3BPB A;  3I4A A;  9JDW A;  2JDX A;  4N24 A;  2DEW X;  4N26 A;  4BOF A;  1G61 A;  1BWD A;  4N2H A;  5M3Q A;  2DEY X;  1WD9 A;  1JDW A;  1S9R A;  1VKP A;  4N2C A;  1G62 A;  5JDW A;  2CI4 A;  4N2I A;  4X8G A;  4N2F A;  2CMU A;  3H7K A;  2CI6 A;  5AN9 I;  1H70 A;  4YTG A;  2JAJ A;  4N22 A;  4N20 A;  2CI3 A;  3B1U A;  4N28 A;  2AAF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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