2CI1A

Crystal structure of dimethylarginine dimethylaminohydrolase i in complex with s-nitroso-lhomocysteine
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
275
structure length
273
Chain Sequence
ATFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTSSVLINKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 98
structure length 273
sequence length 275
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2ci1A00
3P8PA 2DW5A 4N28A 2CMUA 4X8CA 2C6ZA 2CI5A 1JDXA 2DEYX 8JDWA 4N25A 1WD9A 1VKPA 3H7KA 5M3QA 3APNA 3HVMA 4YTGA 1ZBRA 4N2GA 3P8EA 1WD8A 2CI7A 4BOFA 3H7CX 1G62A 1G61A 4YT9A 3JDWA 3B1UA 4N2FA 3I2EA 2CI4A 4YTBA 3B1TA 5AK7A 4N24A 5AN9I 2AAFA 4N20A 1H70A 1LXYA 9JDWA 2ACIA 4N2DA 2CI3A 1XKNA 2CI6A 4X8GA 4N2EA 6JDWA 4DKTA 2JERA 4N2MA 3APMA 2JDXA 4N2HA 1S9RA 2JDWA 3I4AA 2DEXX 4N2KA 2EWOA 4N2LA 3RHYA 3BPBA 4N2NA 2JAIA 5AK8A 1RXXA 4N26A 7JDWA 2Q3UA 1WDAA 2JAJA 2A9GA 4E4JA 4N2CA 1BWDA 4N2AA 4JDWA 4N2IA 4N22A 2DEWX 1JDWA 5JDWA 5HP5A 2ABRA 4N2BA 2CI1A
chains in the Genus database with same CATH superfamily
3P8PA 2DW5A 4N28A 2CMUA 4X8CA 2C6ZA 2CI5A 1JDXA 2DEYX 8JDWA 4N25A 1WD9A 1VKPA 3H7KA 5M3QA 3APNA 3HVMA 4YTGA 1ZBRA 4N2GA 3P8EA 1WD8A 2CI7A 4BOFA 3H7CX 1G62A 1G61A 4YT9A 1YNHA 3JDWA 3B1UA 4N2FA 3I2EA 2CI4A 4YTBA 3B1TA 5AK7A 4N24A 5AN9I 2AAFA 4N20A 1H70A 1LXYA 9JDWA 2ACIA 4N2DA 2CI3A 1XKNA 2CI6A 4X8GA 4N2EA 6JDWA 4DKTA 2JERA 4N2MA 3APMA 2JDXA 4N2HA 1S9RA 2JDWA 3I4AA 2DEXX 4N2KA 2EWOA 4N2LA 3RHYA 3BPBA 4N2NA 2JAIA 5AK8A 1RXXA 4N26A 7JDWA 2Q3UA 1WDAA 2JAJA 2A9GA 4E4JA 4N2CA 1BWDA 4N2AA 4JDWA 4N2IA 4N22A 1YNIA 2DEWX 1JDWA 1YNFA 5JDWA 5HP5A 2ABRA 4N2BA 2CI1A
chains in the Genus database with same CATH topology
3P8PA 2DW5A 4N28A 2CMUA 4X8CA 2C6ZA 2CI5A 1JDXA 2DEYX 8JDWA 4N25A 1WD9A 1VKPA 3H7KA 5M3QA 3APNA 3HVMA 4YTGA 1ZBRA 4N2GA 3P8EA 1WD8A 2CI7A 4BOFA 3H7CX 1G62A 1G61A 4YT9A 3JDWA 3B1UA 4N2FA 3I2EA 2CI4A 4YTBA 3B1TA 5AK7A 4N24A 5AN9I 2AAFA 4N20A 1H70A 1LXYA 9JDWA 2ACIA 4N2DA 2CI3A 1XKNA 2CI6A 4X8GA 4N2EA 6JDWA 4DKTA 2JERA 4N2MA 3APMA 2JDXA 4N2HA 1S9RA 2JDWA 3I4AA 2DEXX 4N2KA 2EWOA 4N2LA 3RHYA 3BPBA 4N2NA 2JAIA 5AK8A 1RXXA 4N26A 7JDWA 2Q3UA 1WDAA 2JAJA 2A9GA 4E4JA 4N2CA 1BWDA 4N2AA 4JDWA 4N2IA 4N22A 2DEWX 1JDWA 5JDWA 5HP5A 2ABRA 4N2BA 2CI1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P8P A;  2DW5 A;  4N28 A;  2CMU A;  4X8C A;  2C6Z A;  2CI5 A;  1JDX A;  2DEY X;  8JDW A;  4N25 A;  1WD9 A;  1VKP A;  3H7K A;  5M3Q A;  3APN A;  3HVM A;  4YTG A;  1ZBR A;  4N2G A;  3P8E A;  1WD8 A;  2CI7 A;  4BOF A;  3H7C X;  1G62 A;  1G61 A;  4YT9 A;  3JDW A;  3B1U A;  4N2F A;  3I2E A;  2CI4 A;  4YTB A;  3B1T A;  5AK7 A;  4N24 A;  5AN9 I;  2AAF A;  4N20 A;  1H70 A;  1LXY A;  9JDW A;  2ACI A;  4N2D A;  2CI3 A;  1XKN A;  2CI6 A;  4X8G A;  4N2E A;  6JDW A;  4DKT A;  2JER A;  4N2M A;  3APM A;  2JDX A;  4N2H A;  1S9R A;  2JDW A;  3I4A A;  2DEX X;  4N2K A;  2EWO A;  4N2L A;  3RHY A;  3BPB A;  4N2N A;  2JAI A;  5AK8 A;  1RXX A;  4N26 A;  7JDW A;  2Q3U A;  1WDA A;  2JAJ A;  2A9G A;  4E4J A;  4N2C A;  1BWD A;  4N2A A;  4JDW A;  4N2I A;  4N22 A;  2DEW X;  1JDW A;  5JDW A;  5HP5 A;  2ABR A;  4N2B A;  2CI1 A; 
#chains in the Genus database with same CATH topology
 3P8P A;  2DW5 A;  4N28 A;  2CMU A;  4X8C A;  2C6Z A;  2CI5 A;  1JDX A;  2DEY X;  8JDW A;  4N25 A;  1WD9 A;  1VKP A;  3H7K A;  5M3Q A;  3APN A;  3HVM A;  4YTG A;  1ZBR A;  4N2G A;  3P8E A;  1WD8 A;  2CI7 A;  4BOF A;  3H7C X;  1G62 A;  1G61 A;  4YT9 A;  1YNH A;  3JDW A;  3B1U A;  4N2F A;  3I2E A;  2CI4 A;  4YTB A;  3B1T A;  5AK7 A;  4N24 A;  5AN9 I;  2AAF A;  4N20 A;  1H70 A;  1LXY A;  9JDW A;  2ACI A;  4N2D A;  2CI3 A;  1XKN A;  2CI6 A;  4X8G A;  4N2E A;  6JDW A;  4DKT A;  2JER A;  4N2M A;  3APM A;  2JDX A;  4N2H A;  1S9R A;  2JDW A;  3I4A A;  2DEX X;  4N2K A;  2EWO A;  4N2L A;  3RHY A;  3BPB A;  4N2N A;  2JAI A;  5AK8 A;  1RXX A;  4N26 A;  7JDW A;  2Q3U A;  1WDA A;  2JAJ A;  2A9G A;  4E4J A;  4N2C A;  1BWD A;  4N2A A;  4JDW A;  4N2I A;  4N22 A;  1YNI A;  2DEW X;  1JDW A;  1YNF A;  5JDW A;  5HP5 A;  2ABR A;  4N2B A;  2CI1 A; 
#chains in the Genus database with same CATH homology
 3P8P A;  2DW5 A;  4N28 A;  2CMU A;  4X8C A;  2C6Z A;  2CI5 A;  1JDX A;  2DEY X;  8JDW A;  4N25 A;  1WD9 A;  1VKP A;  3H7K A;  5M3Q A;  3APN A;  3HVM A;  4YTG A;  1ZBR A;  4N2G A;  3P8E A;  1WD8 A;  2CI7 A;  4BOF A;  3H7C X;  1G62 A;  1G61 A;  4YT9 A;  3JDW A;  3B1U A;  4N2F A;  3I2E A;  2CI4 A;  4YTB A;  3B1T A;  5AK7 A;  4N24 A;  5AN9 I;  2AAF A;  4N20 A;  1H70 A;  1LXY A;  9JDW A;  2ACI A;  4N2D A;  2CI3 A;  1XKN A;  2CI6 A;  4X8G A;  4N2E A;  6JDW A;  4DKT A;  2JER A;  4N2M A;  3APM A;  2JDX A;  4N2H A;  1S9R A;  2JDW A;  3I4A A;  2DEX X;  4N2K A;  2EWO A;  4N2L A;  3RHY A;  3BPB A;  4N2N A;  2JAI A;  5AK8 A;  1RXX A;  4N26 A;  7JDW A;  2Q3U A;  1WDA A;  2JAJ A;  2A9G A;  4E4J A;  4N2C A;  1BWD A;  4N2A A;  4JDW A;  4N2I A;  4N22 A;  2DEW X;  1JDW A;  5JDW A;  5HP5 A;  2ABR A;  4N2B A;  2CI1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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