2CI3A

Crystal structure of dimethylarginine dimethylaminohydrolase crystal form i
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
274
structure length
274
Chain Sequence
ATFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 99
structure length 274
sequence length 274
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2ci3A00
4N2DA 5AK8A 2DEWX 4YTBA 4N20A 4N2LA 2JAJA 5HP5A 2JERA 1BWDA 5M3QA 3P8PA 2A9GA 4DKTA 1G62A 3H7KA 1WD9A 4N2IA 5AK7A 3I4AA 2CI1A 1VKPA 2CI7A 2DEYX 4YT9A 2CI3A 1RXXA 4N2CA 2CMUA 4N25A 3APNA 4YTGA 4X8CA 4N28A 2AAFA 2DW5A 4N2FA 4N2EA 3JDWA 4N26A 2JDXA 9JDWA 4X8GA 2ACIA 2Q3UA 1G61A 3B1TA 3B1UA 4N2MA 4N22A 3RHYA 1LXYA 3HVMA 1XKNA 2JAIA 4N2HA 2C6ZA 1H70A 1ZBRA 4E4JA 4JDWA 3APMA 4N24A 1WDAA 1S9RA 6JDWA 1JDXA 3H7CX 5AN9I 4N2KA 4N2NA 4BOFA 2CI5A 4N2BA 2ABRA 3I2EA 2JDWA 7JDWA 3BPBA 2DEXX 5JDWA 1WD8A 8JDWA 4N2GA 4N2AA 2CI4A 1JDWA 2CI6A 2EWOA 3P8EA
chains in the Genus database with same CATH superfamily
4N2DA 5AK8A 2DEWX 4YTBA 4N20A 4N2LA 2JAJA 5HP5A 2JERA 1BWDA 5M3QA 3P8PA 2A9GA 4DKTA 1G62A 3H7KA 1WD9A 4N2IA 5AK7A 3I4AA 2CI1A 1VKPA 2CI7A 2DEYX 4YT9A 2CI3A 1RXXA 4N2CA 2CMUA 4N25A 3APNA 4YTGA 4X8CA 4N28A 2AAFA 2DW5A 4N2FA 4N2EA 3JDWA 4N26A 2JDXA 9JDWA 4X8GA 2ACIA 2Q3UA 1G61A 3B1TA 3B1UA 4N2MA 4N22A 3RHYA 1LXYA 3HVMA 1XKNA 2JAIA 4N2HA 2C6ZA 1H70A 1ZBRA 1YNIA 4E4JA 4JDWA 1YNHA 3APMA 4N24A 1WDAA 1S9RA 6JDWA 1JDXA 3H7CX 5AN9I 4N2KA 4N2NA 4BOFA 2CI5A 4N2BA 2ABRA 3I2EA 2JDWA 1YNFA 7JDWA 3BPBA 2DEXX 5JDWA 1WD8A 8JDWA 4N2GA 4N2AA 2CI4A 1JDWA 2CI6A 2EWOA 3P8EA
chains in the Genus database with same CATH topology
4N2DA 5AK8A 2DEWX 4YTBA 4N20A 4N2LA 2JAJA 5HP5A 2JERA 1BWDA 5M3QA 3P8PA 2A9GA 4DKTA 1G62A 3H7KA 1WD9A 4N2IA 5AK7A 3I4AA 2CI1A 1VKPA 2CI7A 2DEYX 4YT9A 2CI3A 1RXXA 4N2CA 2CMUA 4N25A 3APNA 4YTGA 4X8CA 4N28A 2AAFA 2DW5A 4N2FA 4N2EA 3JDWA 4N26A 2JDXA 9JDWA 4X8GA 2ACIA 2Q3UA 1G61A 3B1TA 3B1UA 4N2MA 4N22A 3RHYA 1LXYA 3HVMA 1XKNA 2JAIA 4N2HA 2C6ZA 1H70A 1ZBRA 4E4JA 4JDWA 3APMA 4N24A 1WDAA 1S9RA 6JDWA 1JDXA 3H7CX 5AN9I 4N2KA 4N2NA 4BOFA 2CI5A 4N2BA 2ABRA 3I2EA 2JDWA 7JDWA 3BPBA 2DEXX 5JDWA 1WD8A 8JDWA 4N2GA 4N2AA 2CI4A 1JDWA 2CI6A 2EWOA 3P8EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N2D A;  5AK8 A;  2DEW X;  4YTB A;  4N20 A;  4N2L A;  2JAJ A;  5HP5 A;  2JER A;  1BWD A;  5M3Q A;  3P8P A;  2A9G A;  4DKT A;  1G62 A;  3H7K A;  1WD9 A;  4N2I A;  5AK7 A;  3I4A A;  2CI1 A;  1VKP A;  2CI7 A;  2DEY X;  4YT9 A;  2CI3 A;  1RXX A;  4N2C A;  2CMU A;  4N25 A;  3APN A;  4YTG A;  4X8C A;  4N28 A;  2AAF A;  2DW5 A;  4N2F A;  4N2E A;  3JDW A;  4N26 A;  2JDX A;  9JDW A;  4X8G A;  2ACI A;  2Q3U A;  1G61 A;  3B1T A;  3B1U A;  4N2M A;  4N22 A;  3RHY A;  1LXY A;  3HVM A;  1XKN A;  2JAI A;  4N2H A;  2C6Z A;  1H70 A;  1ZBR A;  4E4J A;  4JDW A;  3APM A;  4N24 A;  1WDA A;  1S9R A;  6JDW A;  1JDX A;  3H7C X;  5AN9 I;  4N2K A;  4N2N A;  4BOF A;  2CI5 A;  4N2B A;  2ABR A;  3I2E A;  2JDW A;  7JDW A;  3BPB A;  2DEX X;  5JDW A;  1WD8 A;  8JDW A;  4N2G A;  4N2A A;  2CI4 A;  1JDW A;  2CI6 A;  2EWO A;  3P8E A; 
#chains in the Genus database with same CATH topology
 4N2D A;  5AK8 A;  2DEW X;  4YTB A;  4N20 A;  4N2L A;  2JAJ A;  5HP5 A;  2JER A;  1BWD A;  5M3Q A;  3P8P A;  2A9G A;  4DKT A;  1G62 A;  3H7K A;  1WD9 A;  4N2I A;  5AK7 A;  3I4A A;  2CI1 A;  1VKP A;  2CI7 A;  2DEY X;  4YT9 A;  2CI3 A;  1RXX A;  4N2C A;  2CMU A;  4N25 A;  3APN A;  4YTG A;  4X8C A;  4N28 A;  2AAF A;  2DW5 A;  4N2F A;  4N2E A;  3JDW A;  4N26 A;  2JDX A;  9JDW A;  4X8G A;  2ACI A;  2Q3U A;  1G61 A;  3B1T A;  3B1U A;  4N2M A;  4N22 A;  3RHY A;  1LXY A;  3HVM A;  1XKN A;  2JAI A;  4N2H A;  2C6Z A;  1H70 A;  1ZBR A;  1YNI A;  4E4J A;  4JDW A;  1YNH A;  3APM A;  4N24 A;  1WDA A;  1S9R A;  6JDW A;  1JDX A;  3H7C X;  5AN9 I;  4N2K A;  4N2N A;  4BOF A;  2CI5 A;  4N2B A;  2ABR A;  3I2E A;  2JDW A;  1YNF A;  7JDW A;  3BPB A;  2DEX X;  5JDW A;  1WD8 A;  8JDW A;  4N2G A;  4N2A A;  2CI4 A;  1JDW A;  2CI6 A;  2EWO A;  3P8E A; 
#chains in the Genus database with same CATH homology
 4N2D A;  5AK8 A;  2DEW X;  4YTB A;  4N20 A;  4N2L A;  2JAJ A;  5HP5 A;  2JER A;  1BWD A;  5M3Q A;  3P8P A;  2A9G A;  4DKT A;  1G62 A;  3H7K A;  1WD9 A;  4N2I A;  5AK7 A;  3I4A A;  2CI1 A;  1VKP A;  2CI7 A;  2DEY X;  4YT9 A;  2CI3 A;  1RXX A;  4N2C A;  2CMU A;  4N25 A;  3APN A;  4YTG A;  4X8C A;  4N28 A;  2AAF A;  2DW5 A;  4N2F A;  4N2E A;  3JDW A;  4N26 A;  2JDX A;  9JDW A;  4X8G A;  2ACI A;  2Q3U A;  1G61 A;  3B1T A;  3B1U A;  4N2M A;  4N22 A;  3RHY A;  1LXY A;  3HVM A;  1XKN A;  2JAI A;  4N2H A;  2C6Z A;  1H70 A;  1ZBR A;  4E4J A;  4JDW A;  3APM A;  4N24 A;  1WDA A;  1S9R A;  6JDW A;  1JDX A;  3H7C X;  5AN9 I;  4N2K A;  4N2N A;  4BOF A;  2CI5 A;  4N2B A;  2ABR A;  3I2E A;  2JDW A;  7JDW A;  3BPB A;  2DEX X;  5JDW A;  1WD8 A;  8JDW A;  4N2G A;  4N2A A;  2CI4 A;  1JDW A;  2CI6 A;  2EWO A;  3P8E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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