2CI4A

Crystal structure of dimethylarginine dimethylaminohydrolase i crystal form ii
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
273
structure length
273
Chain Sequence
TFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Mammalian Nos Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 94
structure length 273
sequence length 273
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2ci4A00
9JDWA 3H7KA 1RXXA 5AK7A 4N2IA 2JAJA 2EWOA 3P8PA 3I4AA 1H70A 5HP5A 4N2AA 4N2HA 4DKTA 1G62A 7JDWA 1ZBRA 4E4JA 5AN9I 4N28A 2JAIA 8JDWA 1JDWA 3APNA 2CMUA 4N22A 4N2NA 2DEXX 2CI5A 2ACIA 2ABRA 4X8CA 4N25A 4N2CA 2JDWA 2DW5A 2C6ZA 1BWDA 3B1UA 4N24A 3B1TA 1WD8A 2CI4A 4N2BA 1LXYA 4N20A 1WDAA 1WD9A 4N2GA 3H7CX 1G61A 4N2DA 4YT9A 4JDWA 4N2EA 3BPBA 3APMA 2CI7A 2Q3UA 4N2LA 3RHYA 2JERA 5AK8A 1XKNA 3HVMA 2CI3A 2JDXA 6JDWA 4BOFA 3JDWA 1JDXA 2CI6A 1VKPA 1S9RA 2CI1A 2DEYX 3I2EA 2A9GA 4YTBA 4N2KA 4N2FA 2DEWX 4X8GA 4N26A 2AAFA 3P8EA 4N2MA 4YTGA 5M3QA 5JDWA
chains in the Genus database with same CATH superfamily
9JDWA 3H7KA 1RXXA 5AK7A 4N2IA 2JAJA 2EWOA 3P8PA 3I4AA 1H70A 1YNIA 5HP5A 4N2AA 4N2HA 4DKTA 1G62A 7JDWA 1ZBRA 4E4JA 5AN9I 4N28A 2JAIA 8JDWA 1JDWA 3APNA 1YNHA 2CMUA 4N22A 4N2NA 2DEXX 2CI5A 2ACIA 2ABRA 4X8CA 4N25A 4N2CA 2JDWA 2DW5A 2C6ZA 1BWDA 3B1UA 4N24A 3B1TA 1WD8A 2CI4A 4N2BA 1LXYA 4N20A 1WDAA 1WD9A 4N2GA 3H7CX 1G61A 4N2DA 4YT9A 4JDWA 4N2EA 3BPBA 3APMA 2CI7A 2Q3UA 4N2LA 3RHYA 2JERA 5AK8A 1YNFA 1XKNA 3HVMA 2CI3A 2JDXA 6JDWA 4BOFA 3JDWA 1JDXA 2CI6A 1VKPA 1S9RA 2CI1A 2DEYX 3I2EA 2A9GA 4YTBA 4N2KA 4N2FA 2DEWX 4X8GA 4N26A 2AAFA 3P8EA 4N2MA 4YTGA 5M3QA 5JDWA
chains in the Genus database with same CATH topology
9JDWA 3H7KA 1RXXA 5AK7A 4N2IA 2JAJA 2EWOA 3P8PA 3I4AA 1H70A 5HP5A 4N2AA 4N2HA 4DKTA 1G62A 7JDWA 1ZBRA 4E4JA 5AN9I 4N28A 2JAIA 8JDWA 1JDWA 3APNA 2CMUA 4N22A 4N2NA 2DEXX 2CI5A 2ACIA 2ABRA 4X8CA 4N25A 4N2CA 2JDWA 2DW5A 2C6ZA 1BWDA 3B1UA 4N24A 3B1TA 1WD8A 2CI4A 4N2BA 1LXYA 4N20A 1WDAA 1WD9A 4N2GA 3H7CX 1G61A 4N2DA 4YT9A 4JDWA 4N2EA 3BPBA 3APMA 2CI7A 2Q3UA 4N2LA 3RHYA 2JERA 5AK8A 1XKNA 3HVMA 2CI3A 2JDXA 6JDWA 4BOFA 3JDWA 1JDXA 2CI6A 1VKPA 1S9RA 2CI1A 2DEYX 3I2EA 2A9GA 4YTBA 4N2KA 4N2FA 2DEWX 4X8GA 4N26A 2AAFA 3P8EA 4N2MA 4YTGA 5M3QA 5JDWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 9JDW A;  3H7K A;  1RXX A;  5AK7 A;  4N2I A;  2JAJ A;  2EWO A;  3P8P A;  3I4A A;  1H70 A;  5HP5 A;  4N2A A;  4N2H A;  4DKT A;  1G62 A;  7JDW A;  1ZBR A;  4E4J A;  5AN9 I;  4N28 A;  2JAI A;  8JDW A;  1JDW A;  3APN A;  2CMU A;  4N22 A;  4N2N A;  2DEX X;  2CI5 A;  2ACI A;  2ABR A;  4X8C A;  4N25 A;  4N2C A;  2JDW A;  2DW5 A;  2C6Z A;  1BWD A;  3B1U A;  4N24 A;  3B1T A;  1WD8 A;  2CI4 A;  4N2B A;  1LXY A;  4N20 A;  1WDA A;  1WD9 A;  4N2G A;  3H7C X;  1G61 A;  4N2D A;  4YT9 A;  4JDW A;  4N2E A;  3BPB A;  3APM A;  2CI7 A;  2Q3U A;  4N2L A;  3RHY A;  2JER A;  5AK8 A;  1XKN A;  3HVM A;  2CI3 A;  2JDX A;  6JDW A;  4BOF A;  3JDW A;  1JDX A;  2CI6 A;  1VKP A;  1S9R A;  2CI1 A;  2DEY X;  3I2E A;  2A9G A;  4YTB A;  4N2K A;  4N2F A;  2DEW X;  4X8G A;  4N26 A;  2AAF A;  3P8E A;  4N2M A;  4YTG A;  5M3Q A;  5JDW A; 
#chains in the Genus database with same CATH topology
 9JDW A;  3H7K A;  1RXX A;  5AK7 A;  4N2I A;  2JAJ A;  2EWO A;  3P8P A;  3I4A A;  1H70 A;  1YNI A;  5HP5 A;  4N2A A;  4N2H A;  4DKT A;  1G62 A;  7JDW A;  1ZBR A;  4E4J A;  5AN9 I;  4N28 A;  2JAI A;  8JDW A;  1JDW A;  3APN A;  1YNH A;  2CMU A;  4N22 A;  4N2N A;  2DEX X;  2CI5 A;  2ACI A;  2ABR A;  4X8C A;  4N25 A;  4N2C A;  2JDW A;  2DW5 A;  2C6Z A;  1BWD A;  3B1U A;  4N24 A;  3B1T A;  1WD8 A;  2CI4 A;  4N2B A;  1LXY A;  4N20 A;  1WDA A;  1WD9 A;  4N2G A;  3H7C X;  1G61 A;  4N2D A;  4YT9 A;  4JDW A;  4N2E A;  3BPB A;  3APM A;  2CI7 A;  2Q3U A;  4N2L A;  3RHY A;  2JER A;  5AK8 A;  1YNF A;  1XKN A;  3HVM A;  2CI3 A;  2JDX A;  6JDW A;  4BOF A;  3JDW A;  1JDX A;  2CI6 A;  1VKP A;  1S9R A;  2CI1 A;  2DEY X;  3I2E A;  2A9G A;  4YTB A;  4N2K A;  4N2F A;  2DEW X;  4X8G A;  4N26 A;  2AAF A;  3P8E A;  4N2M A;  4YTG A;  5M3Q A;  5JDW A; 
#chains in the Genus database with same CATH homology
 9JDW A;  3H7K A;  1RXX A;  5AK7 A;  4N2I A;  2JAJ A;  2EWO A;  3P8P A;  3I4A A;  1H70 A;  5HP5 A;  4N2A A;  4N2H A;  4DKT A;  1G62 A;  7JDW A;  1ZBR A;  4E4J A;  5AN9 I;  4N28 A;  2JAI A;  8JDW A;  1JDW A;  3APN A;  2CMU A;  4N22 A;  4N2N A;  2DEX X;  2CI5 A;  2ACI A;  2ABR A;  4X8C A;  4N25 A;  4N2C A;  2JDW A;  2DW5 A;  2C6Z A;  1BWD A;  3B1U A;  4N24 A;  3B1T A;  1WD8 A;  2CI4 A;  4N2B A;  1LXY A;  4N20 A;  1WDA A;  1WD9 A;  4N2G A;  3H7C X;  1G61 A;  4N2D A;  4YT9 A;  4JDW A;  4N2E A;  3BPB A;  3APM A;  2CI7 A;  2Q3U A;  4N2L A;  3RHY A;  2JER A;  5AK8 A;  1XKN A;  3HVM A;  2CI3 A;  2JDX A;  6JDW A;  4BOF A;  3JDW A;  1JDX A;  2CI6 A;  1VKP A;  1S9R A;  2CI1 A;  2DEY X;  3I2E A;  2A9G A;  4YTB A;  4N2K A;  4N2F A;  2DEW X;  4X8G A;  4N26 A;  2AAF A;  3P8E A;  4N2M A;  4YTG A;  5M3Q A;  5JDW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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