2JAIA

Ddah1 complexed with citrulline
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
273
structure length
271
Chain Sequence
AFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLGLQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVGLHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Disruption of methylarginine metabolism impairs vascular homeostasis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords NG, NG-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1
total genus 80
structure length 271
sequence length 273
chains with identical sequence B
ec nomenclature ec 3.5.3.18: Dimethylargininase.
pdb deposition date 2006-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02274 Amidinotransf Amidinotransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 2jaiA00
2CI6A 2DEXX 4JDWA 4N2HA 4N2AA 3APNA 3P8EA 4N2MA 1JDXA 2DEYX 4N20A 4BOFA 3HVMA 2ABRA 4N2FA 1G62A 2AAFA 3BPBA 5JDWA 7JDWA 4N22A 4N24A 4DKTA 2EWOA 1WD9A 2DEWX 1XKNA 5HP5A 3B1UA 4N2LA 2CI5A 4N2EA 3I4AA 6JDWA 4N2CA 1ZBRA 4E4JA 3APMA 4N2NA 5AK8A 3H7KA 1LXYA 5AK7A 1WD8A 1G61A 2JAJA 1BWDA 4X8GA 5M3QA 2CI7A 3JDWA 2CI1A 3I2EA 2JDXA 2CMUA 4N2BA 2ACIA 3RHYA 9JDWA 4N2KA 2C6ZA 1S9RA 4N2IA 1JDWA 1WDAA 4X8CA 4YTGA 1H70A 2Q3UA 3B1TA 1VKPA 4YT9A 2JDWA 4YTBA 3H7CX 2JAIA 2JERA 4N2DA 4N28A 5AN9I 1RXXA 2CI3A 4N25A 4N2GA 2DW5A 2CI4A 2A9GA 8JDWA 3P8PA 4N26A
chains in the Genus database with same CATH superfamily
2CI6A 2DEXX 4JDWA 4N2HA 4N2AA 3APNA 3P8EA 4N2MA 1JDXA 2DEYX 4N20A 4BOFA 3HVMA 2ABRA 4N2FA 1G62A 2AAFA 3BPBA 5JDWA 7JDWA 4N22A 4N24A 4DKTA 2EWOA 1WD9A 2DEWX 1XKNA 5HP5A 3B1UA 4N2LA 2CI5A 4N2EA 3I4AA 6JDWA 4N2CA 1ZBRA 4E4JA 3APMA 4N2NA 1YNHA 5AK8A 3H7KA 1LXYA 5AK7A 1WD8A 1G61A 2JAJA 1BWDA 4X8GA 5M3QA 2CI7A 3JDWA 2CI1A 3I2EA 2JDXA 2CMUA 4N2BA 2ACIA 3RHYA 9JDWA 4N2KA 2C6ZA 1S9RA 4N2IA 1JDWA 1WDAA 4X8CA 4YTGA 1YNFA 1H70A 2Q3UA 3B1TA 1VKPA 4YT9A 2JDWA 4YTBA 3H7CX 2JAIA 2JERA 4N2DA 4N28A 5AN9I 1RXXA 2CI3A 4N25A 4N2GA 2DW5A 2CI4A 1YNIA 2A9GA 8JDWA 3P8PA 4N26A
chains in the Genus database with same CATH topology
2CI6A 2DEXX 4JDWA 4N2HA 4N2AA 3APNA 3P8EA 4N2MA 1JDXA 2DEYX 4N20A 4BOFA 3HVMA 2ABRA 4N2FA 1G62A 2AAFA 3BPBA 5JDWA 7JDWA 4N22A 4N24A 4DKTA 2EWOA 1WD9A 2DEWX 1XKNA 5HP5A 3B1UA 4N2LA 2CI5A 4N2EA 3I4AA 6JDWA 4N2CA 1ZBRA 4E4JA 3APMA 4N2NA 5AK8A 3H7KA 1LXYA 5AK7A 1WD8A 1G61A 2JAJA 1BWDA 4X8GA 5M3QA 2CI7A 3JDWA 2CI1A 3I2EA 2JDXA 2CMUA 4N2BA 2ACIA 3RHYA 9JDWA 4N2KA 2C6ZA 1S9RA 4N2IA 1JDWA 1WDAA 4X8CA 4YTGA 1H70A 2Q3UA 3B1TA 1VKPA 4YT9A 2JDWA 4YTBA 3H7CX 2JAIA 2JERA 4N2DA 4N28A 5AN9I 1RXXA 2CI3A 4N25A 4N2GA 2DW5A 2CI4A 2A9GA 8JDWA 3P8PA 4N26A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CI6 A;  2DEX X;  4JDW A;  4N2H A;  4N2A A;  3APN A;  3P8E A;  4N2M A;  1JDX A;  2DEY X;  4N20 A;  4BOF A;  3HVM A;  2ABR A;  4N2F A;  1G62 A;  2AAF A;  3BPB A;  5JDW A;  7JDW A;  4N22 A;  4N24 A;  4DKT A;  2EWO A;  1WD9 A;  2DEW X;  1XKN A;  5HP5 A;  3B1U A;  4N2L A;  2CI5 A;  4N2E A;  3I4A A;  6JDW A;  4N2C A;  1ZBR A;  4E4J A;  3APM A;  4N2N A;  5AK8 A;  3H7K A;  1LXY A;  5AK7 A;  1WD8 A;  1G61 A;  2JAJ A;  1BWD A;  4X8G A;  5M3Q A;  2CI7 A;  3JDW A;  2CI1 A;  3I2E A;  2JDX A;  2CMU A;  4N2B A;  2ACI A;  3RHY A;  9JDW A;  4N2K A;  2C6Z A;  1S9R A;  4N2I A;  1JDW A;  1WDA A;  4X8C A;  4YTG A;  1H70 A;  2Q3U A;  3B1T A;  1VKP A;  4YT9 A;  2JDW A;  4YTB A;  3H7C X;  2JAI A;  2JER A;  4N2D A;  4N28 A;  5AN9 I;  1RXX A;  2CI3 A;  4N25 A;  4N2G A;  2DW5 A;  2CI4 A;  2A9G A;  8JDW A;  3P8P A;  4N26 A; 
#chains in the Genus database with same CATH topology
 2CI6 A;  2DEX X;  4JDW A;  4N2H A;  4N2A A;  3APN A;  3P8E A;  4N2M A;  1JDX A;  2DEY X;  4N20 A;  4BOF A;  3HVM A;  2ABR A;  4N2F A;  1G62 A;  2AAF A;  3BPB A;  5JDW A;  7JDW A;  4N22 A;  4N24 A;  4DKT A;  2EWO A;  1WD9 A;  2DEW X;  1XKN A;  5HP5 A;  3B1U A;  4N2L A;  2CI5 A;  4N2E A;  3I4A A;  6JDW A;  4N2C A;  1ZBR A;  4E4J A;  3APM A;  4N2N A;  1YNH A;  5AK8 A;  3H7K A;  1LXY A;  5AK7 A;  1WD8 A;  1G61 A;  2JAJ A;  1BWD A;  4X8G A;  5M3Q A;  2CI7 A;  3JDW A;  2CI1 A;  3I2E A;  2JDX A;  2CMU A;  4N2B A;  2ACI A;  3RHY A;  9JDW A;  4N2K A;  2C6Z A;  1S9R A;  4N2I A;  1JDW A;  1WDA A;  4X8C A;  4YTG A;  1YNF A;  1H70 A;  2Q3U A;  3B1T A;  1VKP A;  4YT9 A;  2JDW A;  4YTB A;  3H7C X;  2JAI A;  2JER A;  4N2D A;  4N28 A;  5AN9 I;  1RXX A;  2CI3 A;  4N25 A;  4N2G A;  2DW5 A;  2CI4 A;  1YNI A;  2A9G A;  8JDW A;  3P8P A;  4N26 A; 
#chains in the Genus database with same CATH homology
 2CI6 A;  2DEX X;  4JDW A;  4N2H A;  4N2A A;  3APN A;  3P8E A;  4N2M A;  1JDX A;  2DEY X;  4N20 A;  4BOF A;  3HVM A;  2ABR A;  4N2F A;  1G62 A;  2AAF A;  3BPB A;  5JDW A;  7JDW A;  4N22 A;  4N24 A;  4DKT A;  2EWO A;  1WD9 A;  2DEW X;  1XKN A;  5HP5 A;  3B1U A;  4N2L A;  2CI5 A;  4N2E A;  3I4A A;  6JDW A;  4N2C A;  1ZBR A;  4E4J A;  3APM A;  4N2N A;  5AK8 A;  3H7K A;  1LXY A;  5AK7 A;  1WD8 A;  1G61 A;  2JAJ A;  1BWD A;  4X8G A;  5M3Q A;  2CI7 A;  3JDW A;  2CI1 A;  3I2E A;  2JDX A;  2CMU A;  4N2B A;  2ACI A;  3RHY A;  9JDW A;  4N2K A;  2C6Z A;  1S9R A;  4N2I A;  1JDW A;  1WDA A;  4X8C A;  4YTG A;  1H70 A;  2Q3U A;  3B1T A;  1VKP A;  4YT9 A;  2JDW A;  4YTB A;  3H7C X;  2JAI A;  2JER A;  4N2D A;  4N28 A;  5AN9 I;  1RXX A;  2CI3 A;  4N25 A;  4N2G A;  2DW5 A;  2CI4 A;  2A9G A;  8JDW A;  3P8P A;  4N26 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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