3JC63

Structure of the eukaryotic replicative cmg helicase and pumpjack motion
Total Genus 45

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
313
structure length
269
Chain Sequence
DAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLH

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
AH1 (19-31)AH2 (38-54)EMPTYTII1 (31-34)TIV1 (32-35)TI5 (261-264)3H2 (118-120)AH3 (103-106)AH4 (108-116)AH5 (121-135)S3 (193-203)TIV8 (235-238)TIV7 (232-235)O1 (186-211)S1 (178-180)TIV3 (162-165)TI1 (167-170)TIV4 (172-175)S2 (183-187)TI4 (216-219)S6 (249-260)TIV6 (218-221)TII3 (244-247)TIV5 (186-189)S4 (210-213)Updating...
connected with : NaN
molecule tags Replication
source organism Saccharomyces cerevisiae
publication title Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
pubmed doi rcsb
molecule keywords DNA replication licensing factor MCM2
total genus 45
structure length 269
sequence length 313
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2015-11-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
3 PF00493 MCM MCM P-loop domain
3 PF17207 MCM_OB MCM OB domain
3 PF17855 MCM_lid MCM AAA-lid domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1640.10 Alpha Beta 2-Layer Sandwich mini-chromosome maintenance (MCM) complex, chain A, domain 1 mini-chromosome maintenance (MCM) complex, chain A, domain 1 3jc6301
4YWKA 3JC62 2VL6A 3JC63 4POGA 4YWMA 3JC66 1LTLA 4POFA 5IY0A 4YWLA 4ME3A
chains in the Genus database with same CATH superfamily
4YWKA 3JC62 2VL6A 3JC63 4POGA 3F8TA 4YWMA 3JC66 1LTLA 4POFA 5IY0A 4YWLA 4ME3A
chains in the Genus database with same CATH topology
4YWKA 3JC62 2VL6A 3JC63 4POGA 3F8TA 4YWMA 3JC66 1LTLA 4POFA 5IY0A 4YWLA 4ME3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YWK A;  3JC6 2;  2VL6 A;  3JC6 3;  4POG A;  4YWM A;  3JC6 6;  1LTL A;  4POF A;  5IY0 A;  4YWL A;  4ME3 A; 
#chains in the Genus database with same CATH topology
 4YWK A;  3JC6 2;  2VL6 A;  3JC6 3;  4POG A;  3F8T A;  4YWM A;  3JC6 6;  1LTL A;  4POF A;  5IY0 A;  4YWL A;  4ME3 A; 
#chains in the Genus database with same CATH homology
 4YWK A;  3JC6 2;  2VL6 A;  3JC6 3;  4POG A;  3F8T A;  4YWM A;  3JC6 6;  1LTL A;  4POF A;  5IY0 A;  4YWL A;  4ME3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

Application loaded.