3JDWA

Crystal structure and mechanism of l-arginine: glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords L-ARGININE\:GLYCINE AMIDINOTRANSFERASE
total genus 126
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1997-01-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 3jdwA00
2A9GA 1LXYA 4N2NA 2CMUA 2DEYX 4N2LA 4N2FA 2JAJA 3B1TA 4N28A 3I4AA 1RXXA 2JDWA 3APMA 4E4JA 3H7KA 2C6ZA 1G61A 2CI6A 3I2EA 2DW5A 5M3QA 2CI3A 3P8PA 2CI5A 4JDWA 4N2EA 1JDWA 4N20A 4N22A 4N2AA 4YTBA 4X8GA 4N24A 2JAIA 1JDXA 2CI4A 2EWOA 1WD9A 4N2DA 4YTGA 2CI1A 3B1UA 5HP5A 3P8EA 4N25A 3HVMA 2ABRA 4N2HA 2DEWX 1G62A 1S9RA 5AN9I 1WD8A 1WDAA 5AK7A 4N2IA 1BWDA 4N2GA 2DEXX 4BOFA 3H7CX 1XKNA 2ACIA 6JDWA 1VKPA 5AK8A 3RHYA 2JDXA 4X8CA 5JDWA 4N2BA 7JDWA 3BPBA 1H70A 3APNA 2AAFA 4N2KA 2JERA 4N26A 3JDWA 4N2MA 4YT9A 8JDWA 4DKTA 9JDWA 4N2CA 2Q3UA 2CI7A 1ZBRA
chains in the Genus database with same CATH superfamily
2A9GA 1LXYA 4N2NA 2CMUA 2DEYX 4N2LA 4N2FA 2JAJA 3B1TA 4N28A 3I4AA 1RXXA 2JDWA 3APMA 4E4JA 3H7KA 2C6ZA 1G61A 2CI6A 3I2EA 2DW5A 5M3QA 2CI3A 3P8PA 2CI5A 4JDWA 4N2EA 1YNFA 1JDWA 4N20A 4N22A 4N2AA 4YTBA 4X8GA 4N24A 2JAIA 1JDXA 2CI4A 1YNIA 2EWOA 1WD9A 4N2DA 4YTGA 2CI1A 3B1UA 5HP5A 3P8EA 4N25A 3HVMA 2ABRA 4N2HA 2DEWX 1G62A 1S9RA 5AN9I 1WD8A 1WDAA 5AK7A 4N2IA 1BWDA 4N2GA 2DEXX 1YNHA 4BOFA 3H7CX 1XKNA 2ACIA 6JDWA 1VKPA 5AK8A 3RHYA 2JDXA 4X8CA 5JDWA 4N2BA 7JDWA 3BPBA 1H70A 3APNA 2AAFA 4N2KA 2JERA 4N26A 3JDWA 4N2MA 4YT9A 8JDWA 4DKTA 9JDWA 4N2CA 2Q3UA 2CI7A 1ZBRA
chains in the Genus database with same CATH topology
2A9GA 1LXYA 4N2NA 2CMUA 2DEYX 4N2LA 4N2FA 2JAJA 3B1TA 4N28A 3I4AA 1RXXA 2JDWA 3APMA 4E4JA 3H7KA 2C6ZA 1G61A 2CI6A 3I2EA 2DW5A 5M3QA 2CI3A 3P8PA 2CI5A 4JDWA 4N2EA 1JDWA 4N20A 4N22A 4N2AA 4YTBA 4X8GA 4N24A 2JAIA 1JDXA 2CI4A 2EWOA 1WD9A 4N2DA 4YTGA 2CI1A 3B1UA 5HP5A 3P8EA 4N25A 3HVMA 2ABRA 4N2HA 2DEWX 1G62A 1S9RA 5AN9I 1WD8A 1WDAA 5AK7A 4N2IA 1BWDA 4N2GA 2DEXX 4BOFA 3H7CX 1XKNA 2ACIA 6JDWA 1VKPA 5AK8A 3RHYA 2JDXA 4X8CA 5JDWA 4N2BA 7JDWA 3BPBA 1H70A 3APNA 2AAFA 4N2KA 2JERA 4N26A 3JDWA 4N2MA 4YT9A 8JDWA 4DKTA 9JDWA 4N2CA 2Q3UA 2CI7A 1ZBRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A9G A;  1LXY A;  4N2N A;  2CMU A;  2DEY X;  4N2L A;  4N2F A;  2JAJ A;  3B1T A;  4N28 A;  3I4A A;  1RXX A;  2JDW A;  3APM A;  4E4J A;  3H7K A;  2C6Z A;  1G61 A;  2CI6 A;  3I2E A;  2DW5 A;  5M3Q A;  2CI3 A;  3P8P A;  2CI5 A;  4JDW A;  4N2E A;  1JDW A;  4N20 A;  4N22 A;  4N2A A;  4YTB A;  4X8G A;  4N24 A;  2JAI A;  1JDX A;  2CI4 A;  2EWO A;  1WD9 A;  4N2D A;  4YTG A;  2CI1 A;  3B1U A;  5HP5 A;  3P8E A;  4N25 A;  3HVM A;  2ABR A;  4N2H A;  2DEW X;  1G62 A;  1S9R A;  5AN9 I;  1WD8 A;  1WDA A;  5AK7 A;  4N2I A;  1BWD A;  4N2G A;  2DEX X;  4BOF A;  3H7C X;  1XKN A;  2ACI A;  6JDW A;  1VKP A;  5AK8 A;  3RHY A;  2JDX A;  4X8C A;  5JDW A;  4N2B A;  7JDW A;  3BPB A;  1H70 A;  3APN A;  2AAF A;  4N2K A;  2JER A;  4N26 A;  3JDW A;  4N2M A;  4YT9 A;  8JDW A;  4DKT A;  9JDW A;  4N2C A;  2Q3U A;  2CI7 A;  1ZBR A; 
#chains in the Genus database with same CATH topology
 2A9G A;  1LXY A;  4N2N A;  2CMU A;  2DEY X;  4N2L A;  4N2F A;  2JAJ A;  3B1T A;  4N28 A;  3I4A A;  1RXX A;  2JDW A;  3APM A;  4E4J A;  3H7K A;  2C6Z A;  1G61 A;  2CI6 A;  3I2E A;  2DW5 A;  5M3Q A;  2CI3 A;  3P8P A;  2CI5 A;  4JDW A;  4N2E A;  1YNF A;  1JDW A;  4N20 A;  4N22 A;  4N2A A;  4YTB A;  4X8G A;  4N24 A;  2JAI A;  1JDX A;  2CI4 A;  1YNI A;  2EWO A;  1WD9 A;  4N2D A;  4YTG A;  2CI1 A;  3B1U A;  5HP5 A;  3P8E A;  4N25 A;  3HVM A;  2ABR A;  4N2H A;  2DEW X;  1G62 A;  1S9R A;  5AN9 I;  1WD8 A;  1WDA A;  5AK7 A;  4N2I A;  1BWD A;  4N2G A;  2DEX X;  1YNH A;  4BOF A;  3H7C X;  1XKN A;  2ACI A;  6JDW A;  1VKP A;  5AK8 A;  3RHY A;  2JDX A;  4X8C A;  5JDW A;  4N2B A;  7JDW A;  3BPB A;  1H70 A;  3APN A;  2AAF A;  4N2K A;  2JER A;  4N26 A;  3JDW A;  4N2M A;  4YT9 A;  8JDW A;  4DKT A;  9JDW A;  4N2C A;  2Q3U A;  2CI7 A;  1ZBR A; 
#chains in the Genus database with same CATH homology
 2A9G A;  1LXY A;  4N2N A;  2CMU A;  2DEY X;  4N2L A;  4N2F A;  2JAJ A;  3B1T A;  4N28 A;  3I4A A;  1RXX A;  2JDW A;  3APM A;  4E4J A;  3H7K A;  2C6Z A;  1G61 A;  2CI6 A;  3I2E A;  2DW5 A;  5M3Q A;  2CI3 A;  3P8P A;  2CI5 A;  4JDW A;  4N2E A;  1JDW A;  4N20 A;  4N22 A;  4N2A A;  4YTB A;  4X8G A;  4N24 A;  2JAI A;  1JDX A;  2CI4 A;  2EWO A;  1WD9 A;  4N2D A;  4YTG A;  2CI1 A;  3B1U A;  5HP5 A;  3P8E A;  4N25 A;  3HVM A;  2ABR A;  4N2H A;  2DEW X;  1G62 A;  1S9R A;  5AN9 I;  1WD8 A;  1WDA A;  5AK7 A;  4N2I A;  1BWD A;  4N2G A;  2DEX X;  4BOF A;  3H7C X;  1XKN A;  2ACI A;  6JDW A;  1VKP A;  5AK8 A;  3RHY A;  2JDX A;  4X8C A;  5JDW A;  4N2B A;  7JDW A;  3BPB A;  1H70 A;  3APN A;  2AAF A;  4N2K A;  2JER A;  4N26 A;  3JDW A;  4N2M A;  4YT9 A;  8JDW A;  4DKT A;  9JDW A;  4N2C A;  2Q3U A;  2CI7 A;  1ZBR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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