3JDWA

Crystal structure and mechanism of l-arginine: glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords L-ARGININE\:GLYCINE AMIDINOTRANSFERASE
total genus 126
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1997-01-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 3jdwA00
1G62A 3B1TA 3P8PA 3RHYA 2ABRA 3H7CX 3BPBA 5AN9I 8JDWA 9JDWA 7JDWA 2CI7A 4N2CA 4DKTA 4YT9A 4YTBA 4YTGA 5HP5A 5AK7A 3I2EA 1XKNA 6JDWA 2JDWA 2CI4A 4N26A 4N28A 4N2BA 3APNA 3APMA 1G61A 4N2NA 1WD9A 4N2GA 4N2KA 3B1UA 1VKPA 4N2AA 4N2EA 2C6ZA 1WDAA 2JAIA 2CI1A 4N22A 2AAFA 4N2LA 3P8EA 5JDWA 4BOFA 2CMUA 2EWOA 1ZBRA 1S9RA 4N24A 1JDWA 2Q3UA 1RXXA 4N2DA 3I4AA 3H7KA 4N2MA 2CI3A 3JDWA 2DEXX 2CI6A 2JAJA 4E4JA 5AK8A 1WD8A 1BWDA 4JDWA 4X8GA 5M3QA 4X8CA 3HVMA 4N2IA 1H70A 2A9GA 2DEWX 4N2FA 2ACIA 2JERA 2CI5A 4N20A 1JDXA 2DEYX 4N2HA 4N25A 2JDXA 1LXYA 2DW5A
chains in the Genus database with same CATH superfamily
1G62A 3B1TA 3P8PA 3RHYA 2ABRA 3H7CX 3BPBA 5AN9I 8JDWA 9JDWA 7JDWA 2CI7A 4N2CA 4DKTA 4YT9A 4YTBA 4YTGA 5HP5A 5AK7A 3I2EA 1XKNA 6JDWA 2JDWA 2CI4A 4N26A 4N28A 4N2BA 3APNA 3APMA 1G61A 4N2NA 1WD9A 1YNIA 4N2GA 4N2KA 3B1UA 1VKPA 4N2AA 4N2EA 2C6ZA 1WDAA 2JAIA 2CI1A 4N22A 2AAFA 4N2LA 3P8EA 5JDWA 4BOFA 2CMUA 2EWOA 1S9RA 1ZBRA 4N24A 1JDWA 2Q3UA 1RXXA 4N2DA 3I4AA 3H7KA 4N2MA 2CI3A 1YNHA 3JDWA 2DEXX 2CI6A 2JAJA 4E4JA 5AK8A 1WD8A 1BWDA 4JDWA 4X8GA 5M3QA 4X8CA 3HVMA 4N2IA 1H70A 2A9GA 2DEWX 4N2FA 2ACIA 2JERA 2CI5A 4N20A 1JDXA 1YNFA 2DEYX 4N2HA 4N25A 2JDXA 1LXYA 2DW5A
chains in the Genus database with same CATH topology
1G62A 3B1TA 3P8PA 3RHYA 2ABRA 3H7CX 3BPBA 5AN9I 8JDWA 9JDWA 7JDWA 2CI7A 4N2CA 4DKTA 4YT9A 4YTBA 4YTGA 5HP5A 5AK7A 3I2EA 1XKNA 6JDWA 2JDWA 2CI4A 4N26A 4N28A 4N2BA 3APNA 3APMA 1G61A 4N2NA 1WD9A 4N2GA 4N2KA 3B1UA 1VKPA 4N2AA 4N2EA 2C6ZA 1WDAA 2JAIA 2CI1A 4N22A 2AAFA 4N2LA 3P8EA 5JDWA 4BOFA 2CMUA 2EWOA 1ZBRA 1S9RA 4N24A 1JDWA 2Q3UA 1RXXA 4N2DA 3I4AA 3H7KA 4N2MA 2CI3A 3JDWA 2DEXX 2CI6A 2JAJA 4E4JA 5AK8A 1WD8A 1BWDA 4JDWA 4X8GA 5M3QA 4X8CA 3HVMA 4N2IA 1H70A 2A9GA 2DEWX 4N2FA 2ACIA 2JERA 2CI5A 4N20A 1JDXA 2DEYX 4N2HA 4N25A 2JDXA 1LXYA 2DW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G62 A;  3B1T A;  3P8P A;  3RHY A;  2ABR A;  3H7C X;  3BPB A;  5AN9 I;  8JDW A;  9JDW A;  7JDW A;  2CI7 A;  4N2C A;  4DKT A;  4YT9 A;  4YTB A;  4YTG A;  5HP5 A;  5AK7 A;  3I2E A;  1XKN A;  6JDW A;  2JDW A;  2CI4 A;  4N26 A;  4N28 A;  4N2B A;  3APN A;  3APM A;  1G61 A;  4N2N A;  1WD9 A;  4N2G A;  4N2K A;  3B1U A;  1VKP A;  4N2A A;  4N2E A;  2C6Z A;  1WDA A;  2JAI A;  2CI1 A;  4N22 A;  2AAF A;  4N2L A;  3P8E A;  5JDW A;  4BOF A;  2CMU A;  2EWO A;  1ZBR A;  1S9R A;  4N24 A;  1JDW A;  2Q3U A;  1RXX A;  4N2D A;  3I4A A;  3H7K A;  4N2M A;  2CI3 A;  3JDW A;  2DEX X;  2CI6 A;  2JAJ A;  4E4J A;  5AK8 A;  1WD8 A;  1BWD A;  4JDW A;  4X8G A;  5M3Q A;  4X8C A;  3HVM A;  4N2I A;  1H70 A;  2A9G A;  2DEW X;  4N2F A;  2ACI A;  2JER A;  2CI5 A;  4N20 A;  1JDX A;  2DEY X;  4N2H A;  4N25 A;  2JDX A;  1LXY A;  2DW5 A; 
#chains in the Genus database with same CATH topology
 1G62 A;  3B1T A;  3P8P A;  3RHY A;  2ABR A;  3H7C X;  3BPB A;  5AN9 I;  8JDW A;  9JDW A;  7JDW A;  2CI7 A;  4N2C A;  4DKT A;  4YT9 A;  4YTB A;  4YTG A;  5HP5 A;  5AK7 A;  3I2E A;  1XKN A;  6JDW A;  2JDW A;  2CI4 A;  4N26 A;  4N28 A;  4N2B A;  3APN A;  3APM A;  1G61 A;  4N2N A;  1WD9 A;  1YNI A;  4N2G A;  4N2K A;  3B1U A;  1VKP A;  4N2A A;  4N2E A;  2C6Z A;  1WDA A;  2JAI A;  2CI1 A;  4N22 A;  2AAF A;  4N2L A;  3P8E A;  5JDW A;  4BOF A;  2CMU A;  2EWO A;  1S9R A;  1ZBR A;  4N24 A;  1JDW A;  2Q3U A;  1RXX A;  4N2D A;  3I4A A;  3H7K A;  4N2M A;  2CI3 A;  1YNH A;  3JDW A;  2DEX X;  2CI6 A;  2JAJ A;  4E4J A;  5AK8 A;  1WD8 A;  1BWD A;  4JDW A;  4X8G A;  5M3Q A;  4X8C A;  3HVM A;  4N2I A;  1H70 A;  2A9G A;  2DEW X;  4N2F A;  2ACI A;  2JER A;  2CI5 A;  4N20 A;  1JDX A;  1YNF A;  2DEY X;  4N2H A;  4N25 A;  2JDX A;  1LXY A;  2DW5 A; 
#chains in the Genus database with same CATH homology
 1G62 A;  3B1T A;  3P8P A;  3RHY A;  2ABR A;  3H7C X;  3BPB A;  5AN9 I;  8JDW A;  9JDW A;  7JDW A;  2CI7 A;  4N2C A;  4DKT A;  4YT9 A;  4YTB A;  4YTG A;  5HP5 A;  5AK7 A;  3I2E A;  1XKN A;  6JDW A;  2JDW A;  2CI4 A;  4N26 A;  4N28 A;  4N2B A;  3APN A;  3APM A;  1G61 A;  4N2N A;  1WD9 A;  4N2G A;  4N2K A;  3B1U A;  1VKP A;  4N2A A;  4N2E A;  2C6Z A;  1WDA A;  2JAI A;  2CI1 A;  4N22 A;  2AAF A;  4N2L A;  3P8E A;  5JDW A;  4BOF A;  2CMU A;  2EWO A;  1ZBR A;  1S9R A;  4N24 A;  1JDW A;  2Q3U A;  1RXX A;  4N2D A;  3I4A A;  3H7K A;  4N2M A;  2CI3 A;  3JDW A;  2DEX X;  2CI6 A;  2JAJ A;  4E4J A;  5AK8 A;  1WD8 A;  1BWD A;  4JDW A;  4X8G A;  5M3Q A;  4X8C A;  3HVM A;  4N2I A;  1H70 A;  2A9G A;  2DEW X;  4N2F A;  2ACI A;  2JER A;  2CI5 A;  4N20 A;  1JDX A;  2DEY X;  4N2H A;  4N25 A;  2JDX A;  1LXY A;  2DW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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