4JDWA

Crystal structure and mechanism of l-arginine: glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHAWTCDVRRRGTLQSYLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords L-ARGININE\:GLYCINE AMIDINOTRANSFERASE
total genus 119
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1997-01-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 4jdwA00
1G62A 4N2GA 1G61A 3APNA 6JDWA 4N22A 1LXYA 3I2EA 5AK7A 4N2EA 1VKPA 4JDWA 2JERA 4N2CA 5M3QA 4BOFA 1WDAA 2AAFA 3JDWA 2JDXA 4X8CA 4N2DA 2CI7A 4N20A 4N2IA 2CI6A 4E4JA 3RHYA 4N2MA 4YTGA 2CI5A 1JDXA 1WD8A 2JAIA 2CMUA 2C6ZA 5AN9I 2ACIA 1ZBRA 9JDWA 4X8GA 4DKTA 4N2BA 4N2LA 3H7KA 2DEWX 2EWOA 1S9RA 4N25A 4N2NA 3H7CX 4N2FA 2DEXX 3BPBA 3B1TA 5AK8A 3HVMA 3P8EA 2CI4A 3P8PA 3I4AA 1WD9A 4YTBA 4N26A 1JDWA 2CI1A 3B1UA 2A9GA 2CI3A 4N24A 4N2HA 2ABRA 2DW5A 1H70A 4N2KA 2JDWA 7JDWA 2DEYX 4N28A 3APMA 5HP5A 8JDWA 2Q3UA 2JAJA 5JDWA 1XKNA 4N2AA 1RXXA 1BWDA 4YT9A
chains in the Genus database with same CATH superfamily
1G62A 4N2GA 1G61A 3APNA 1YNHA 6JDWA 4N22A 1LXYA 3I2EA 5AK7A 4N2EA 1VKPA 4JDWA 2JERA 4N2CA 5M3QA 4BOFA 1WDAA 2AAFA 3JDWA 2JDXA 4X8CA 4N2DA 2CI7A 4N20A 4N2IA 2CI6A 4E4JA 3RHYA 4N2MA 4YTGA 1YNIA 2CI5A 1JDXA 1WD8A 2JAIA 2CMUA 2C6ZA 5AN9I 2ACIA 1ZBRA 9JDWA 4X8GA 4DKTA 4N2BA 4N2LA 3H7KA 2DEWX 2EWOA 1S9RA 4N25A 4N2NA 3H7CX 4N2FA 2DEXX 3BPBA 3B1TA 5AK8A 3HVMA 3P8EA 2CI4A 3P8PA 3I4AA 1WD9A 1YNFA 4YTBA 4N26A 1JDWA 2CI1A 3B1UA 2A9GA 2CI3A 4N24A 4N2HA 2ABRA 2DW5A 1H70A 4N2KA 2JDWA 7JDWA 2DEYX 4N28A 3APMA 5HP5A 8JDWA 2Q3UA 2JAJA 5JDWA 1XKNA 4N2AA 1RXXA 1BWDA 4YT9A
chains in the Genus database with same CATH topology
1G62A 4N2GA 1G61A 3APNA 6JDWA 4N22A 1LXYA 3I2EA 5AK7A 4N2EA 1VKPA 4JDWA 2JERA 4N2CA 5M3QA 4BOFA 1WDAA 2AAFA 3JDWA 2JDXA 4X8CA 4N2DA 2CI7A 4N20A 4N2IA 2CI6A 4E4JA 3RHYA 4N2MA 4YTGA 2CI5A 1JDXA 1WD8A 2JAIA 2CMUA 2C6ZA 5AN9I 2ACIA 1ZBRA 9JDWA 4X8GA 4DKTA 4N2BA 4N2LA 3H7KA 2DEWX 2EWOA 1S9RA 4N25A 4N2NA 3H7CX 4N2FA 2DEXX 3BPBA 3B1TA 5AK8A 3HVMA 3P8EA 2CI4A 3P8PA 3I4AA 1WD9A 4YTBA 4N26A 1JDWA 2CI1A 3B1UA 2A9GA 2CI3A 4N24A 4N2HA 2ABRA 2DW5A 1H70A 4N2KA 2JDWA 7JDWA 2DEYX 4N28A 3APMA 5HP5A 8JDWA 2Q3UA 2JAJA 5JDWA 1XKNA 4N2AA 1RXXA 1BWDA 4YT9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G62 A;  4N2G A;  1G61 A;  3APN A;  6JDW A;  4N22 A;  1LXY A;  3I2E A;  5AK7 A;  4N2E A;  1VKP A;  4JDW A;  2JER A;  4N2C A;  5M3Q A;  4BOF A;  1WDA A;  2AAF A;  3JDW A;  2JDX A;  4X8C A;  4N2D A;  2CI7 A;  4N20 A;  4N2I A;  2CI6 A;  4E4J A;  3RHY A;  4N2M A;  4YTG A;  2CI5 A;  1JDX A;  1WD8 A;  2JAI A;  2CMU A;  2C6Z A;  5AN9 I;  2ACI A;  1ZBR A;  9JDW A;  4X8G A;  4DKT A;  4N2B A;  4N2L A;  3H7K A;  2DEW X;  2EWO A;  1S9R A;  4N25 A;  4N2N A;  3H7C X;  4N2F A;  2DEX X;  3BPB A;  3B1T A;  5AK8 A;  3HVM A;  3P8E A;  2CI4 A;  3P8P A;  3I4A A;  1WD9 A;  4YTB A;  4N26 A;  1JDW A;  2CI1 A;  3B1U A;  2A9G A;  2CI3 A;  4N24 A;  4N2H A;  2ABR A;  2DW5 A;  1H70 A;  4N2K A;  2JDW A;  7JDW A;  2DEY X;  4N28 A;  3APM A;  5HP5 A;  8JDW A;  2Q3U A;  2JAJ A;  5JDW A;  1XKN A;  4N2A A;  1RXX A;  1BWD A;  4YT9 A; 
#chains in the Genus database with same CATH topology
 1G62 A;  4N2G A;  1G61 A;  3APN A;  1YNH A;  6JDW A;  4N22 A;  1LXY A;  3I2E A;  5AK7 A;  4N2E A;  1VKP A;  4JDW A;  2JER A;  4N2C A;  5M3Q A;  4BOF A;  1WDA A;  2AAF A;  3JDW A;  2JDX A;  4X8C A;  4N2D A;  2CI7 A;  4N20 A;  4N2I A;  2CI6 A;  4E4J A;  3RHY A;  4N2M A;  4YTG A;  1YNI A;  2CI5 A;  1JDX A;  1WD8 A;  2JAI A;  2CMU A;  2C6Z A;  5AN9 I;  2ACI A;  1ZBR A;  9JDW A;  4X8G A;  4DKT A;  4N2B A;  4N2L A;  3H7K A;  2DEW X;  2EWO A;  1S9R A;  4N25 A;  4N2N A;  3H7C X;  4N2F A;  2DEX X;  3BPB A;  3B1T A;  5AK8 A;  3HVM A;  3P8E A;  2CI4 A;  3P8P A;  3I4A A;  1WD9 A;  1YNF A;  4YTB A;  4N26 A;  1JDW A;  2CI1 A;  3B1U A;  2A9G A;  2CI3 A;  4N24 A;  4N2H A;  2ABR A;  2DW5 A;  1H70 A;  4N2K A;  2JDW A;  7JDW A;  2DEY X;  4N28 A;  3APM A;  5HP5 A;  8JDW A;  2Q3U A;  2JAJ A;  5JDW A;  1XKN A;  4N2A A;  1RXX A;  1BWD A;  4YT9 A; 
#chains in the Genus database with same CATH homology
 1G62 A;  4N2G A;  1G61 A;  3APN A;  6JDW A;  4N22 A;  1LXY A;  3I2E A;  5AK7 A;  4N2E A;  1VKP A;  4JDW A;  2JER A;  4N2C A;  5M3Q A;  4BOF A;  1WDA A;  2AAF A;  3JDW A;  2JDX A;  4X8C A;  4N2D A;  2CI7 A;  4N20 A;  4N2I A;  2CI6 A;  4E4J A;  3RHY A;  4N2M A;  4YTG A;  2CI5 A;  1JDX A;  1WD8 A;  2JAI A;  2CMU A;  2C6Z A;  5AN9 I;  2ACI A;  1ZBR A;  9JDW A;  4X8G A;  4DKT A;  4N2B A;  4N2L A;  3H7K A;  2DEW X;  2EWO A;  1S9R A;  4N25 A;  4N2N A;  3H7C X;  4N2F A;  2DEX X;  3BPB A;  3B1T A;  5AK8 A;  3HVM A;  3P8E A;  2CI4 A;  3P8P A;  3I4A A;  1WD9 A;  4YTB A;  4N26 A;  1JDW A;  2CI1 A;  3B1U A;  2A9G A;  2CI3 A;  4N24 A;  4N2H A;  2ABR A;  2DW5 A;  1H70 A;  4N2K A;  2JDW A;  7JDW A;  2DEY X;  4N28 A;  3APM A;  5HP5 A;  8JDW A;  2Q3U A;  2JAJ A;  5JDW A;  1XKN A;  4N2A A;  1RXX A;  1BWD A;  4YT9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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