4TPVA

Crystal structure of hookworm platelet inhibitor
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
182
structure length
182
Chain Sequence
DYSLCQQREKLDDDMREMFTELHNGYRAAFARNYKTSKMRTMVYDCTLEEKAYKSAEKCSEEPSSEEENVDVFSAATLNIPLEAGNSWWSEIFELRGKVYNKNGKTSNIANMVWDSHDKLGCAVVDCSGKTHVVCQYGPEAKGDGKTIYEEGAPCSRCSDYGAGVTCDDDWQNLLCIGHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of hookworm platelet inhibitor (HPI), a CAP superfamily member from Ancylostoma caninum.
pubmed doi rcsb
molecule keywords Platelet inhibitor
molecule tags Blood clotting
source organism Ancylostoma caninum
total genus 65
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00188 CAP Cysteine-rich secretory protein family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.33.10 Alpha Beta 3-Layer(aba) Sandwich Pathogenesis-related Protein p14a CAP 4tpvA00
3S6VA 2GIZA 4H0AA 3S6UA 4NUNA 2DDBA 4P27A 5JYSA 1CFEA 2VZNA 1RC9A 1XX5A 3U3LC 4AIWA 3Q2UA 4D53A 2EPFA 4IFAA 4NUIA 4NUKA 3U3NC 4NUOA 4TPVA 3U3UC 4LY5A 1U53A 5ETEA 3NT8A 3S6SA 4G2UA 1QNXA 1WVRA 3MZ8A 2DDAA 3Q2RA 1SMBA 1XTAA
chains in the Genus database with same CATH superfamily
3S6VA 2GIZA 4H0AA 3S6UA 4NUNA 2DDBA 4P27A 5JYSA 1CFEA 2VZNA 1RC9A 1XX5A 3U3LC 4AIWA 3Q2UA 4D53A 2EPFA 4IFAA 4NUIA 4NUKA 3U3NC 4NUOA 4TPVA 3U3UC 4LY5A 1U53A 5ETEA 3NT8A 3S6SA 4G2UA 1QNXA 1WVRA 3MZ8A 2DDAA 3Q2RA 1SMBA 1XTAA
chains in the Genus database with same CATH topology
3S6VA 2GIZA 4H0AA 3S6UA 4NUNA 2DDBA 4P27A 5JYSA 1CFEA 2VZNA 1RC9A 1XX5A 3U3LC 4AIWA 3Q2UA 4D53A 2EPFA 4IFAA 4NUIA 4NUKA 3U3NC 4NUOA 4TPVA 3U3UC 4LY5A 1U53A 5ETEA 3NT8A 3S6SA 4G2UA 1QNXA 1WVRA 3MZ8A 2DDAA 3Q2RA 1SMBA 1XTAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S6V A;  2GIZ A;  4H0A A;  3S6U A;  4NUN A;  2DDB A;  4P27 A;  5JYS A;  1CFE A;  2VZN A;  1RC9 A;  1XX5 A;  3U3L C;  4AIW A;  3Q2U A;  4D53 A;  2EPF A;  4IFA A;  4NUI A;  4NUK A;  3U3N C;  4NUO A;  4TPV A;  3U3U C;  4LY5 A;  1U53 A;  5ETE A;  3NT8 A;  3S6S A;  4G2U A;  1QNX A;  1WVR A;  3MZ8 A;  2DDA A;  3Q2R A;  1SMB A;  1XTA A; 
#chains in the Genus database with same CATH topology
 3S6V A;  2GIZ A;  4H0A A;  3S6U A;  4NUN A;  2DDB A;  4P27 A;  5JYS A;  1CFE A;  2VZN A;  1RC9 A;  1XX5 A;  3U3L C;  4AIW A;  3Q2U A;  4D53 A;  2EPF A;  4IFA A;  4NUI A;  4NUK A;  3U3N C;  4NUO A;  4TPV A;  3U3U C;  4LY5 A;  1U53 A;  5ETE A;  3NT8 A;  3S6S A;  4G2U A;  1QNX A;  1WVR A;  3MZ8 A;  2DDA A;  3Q2R A;  1SMB A;  1XTA A; 
#chains in the Genus database with same CATH homology
 3S6V A;  2GIZ A;  4H0A A;  3S6U A;  4NUN A;  2DDB A;  4P27 A;  5JYS A;  1CFE A;  2VZN A;  1RC9 A;  1XX5 A;  3U3L C;  4AIW A;  3Q2U A;  4D53 A;  2EPF A;  4IFA A;  4NUI A;  4NUK A;  3U3N C;  4NUO A;  4TPV A;  3U3U C;  4LY5 A;  1U53 A;  5ETE A;  3NT8 A;  3S6S A;  4G2U A;  1QNX A;  1WVR A;  3MZ8 A;  2DDA A;  3Q2R A;  1SMB A;  1XTA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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