4TPVA

Crystal structure of hookworm platelet inhibitor
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
182
structure length
182
Chain Sequence
DYSLCQQREKLDDDMREMFTELHNGYRAAFARNYKTSKMRTMVYDCTLEEKAYKSAEKCSEEPSSEEENVDVFSAATLNIPLEAGNSWWSEIFELRGKVYNKNGKTSNIANMVWDSHDKLGCAVVDCSGKTHVVCQYGPEAKGDGKTIYEEGAPCSRCSDYGAGVTCDDDWQNLLCIGHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of hookworm platelet inhibitor (HPI), a CAP superfamily member from Ancylostoma caninum.
pubmed doi rcsb
molecule tags Blood clotting
source organism Ancylostoma caninum
molecule keywords Platelet inhibitor
total genus 65
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00188 CAP Cysteine-rich secretory protein family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.33.10 Alpha Beta 3-Layer(aba) Sandwich Pathogenesis-related Protein p14a CAP 4tpvA00
4D53A 1U53A 4TPVA 3S6UA 2VZNA 3Q2UA 1XX5A 4NUOA 4NUIA 5ETEA 2DDAA 1SMBA 1WVRA 4NUNA 4LY5A 3NT8A 3S6SA 1RC9A 3S6VA 1QNXA 2DDBA 3U3UC 4AIWA 4P27A 4G2UA 4IFAA 2EPFA 3U3LC 3Q2RA 4NUKA 4H0AA 5JYSA 1XTAA 3MZ8A 1CFEA 3U3NC 2GIZA
chains in the Genus database with same CATH superfamily
4D53A 1U53A 4TPVA 3S6UA 2VZNA 3Q2UA 1XX5A 4NUOA 4NUIA 5ETEA 2DDAA 1SMBA 1WVRA 4NUNA 4LY5A 3NT8A 3S6SA 1RC9A 3S6VA 1QNXA 2DDBA 3U3UC 4AIWA 4P27A 4G2UA 4IFAA 2EPFA 3U3LC 3Q2RA 4NUKA 4H0AA 5JYSA 1XTAA 3MZ8A 1CFEA 3U3NC 2GIZA
chains in the Genus database with same CATH topology
4D53A 1U53A 4TPVA 3S6UA 2VZNA 3Q2UA 1XX5A 4NUOA 4NUIA 5ETEA 2DDAA 1SMBA 1WVRA 4NUNA 4LY5A 3NT8A 3S6SA 1RC9A 3S6VA 1QNXA 2DDBA 3U3UC 4AIWA 4P27A 4G2UA 4IFAA 2EPFA 3U3LC 3Q2RA 4NUKA 4H0AA 5JYSA 1XTAA 3MZ8A 1CFEA 3U3NC 2GIZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D53 A;  1U53 A;  4TPV A;  3S6U A;  2VZN A;  3Q2U A;  1XX5 A;  4NUO A;  4NUI A;  5ETE A;  2DDA A;  1SMB A;  1WVR A;  4NUN A;  4LY5 A;  3NT8 A;  3S6S A;  1RC9 A;  3S6V A;  1QNX A;  2DDB A;  3U3U C;  4AIW A;  4P27 A;  4G2U A;  4IFA A;  2EPF A;  3U3L C;  3Q2R A;  4NUK A;  4H0A A;  5JYS A;  1XTA A;  3MZ8 A;  1CFE A;  3U3N C;  2GIZ A; 
#chains in the Genus database with same CATH topology
 4D53 A;  1U53 A;  4TPV A;  3S6U A;  2VZN A;  3Q2U A;  1XX5 A;  4NUO A;  4NUI A;  5ETE A;  2DDA A;  1SMB A;  1WVR A;  4NUN A;  4LY5 A;  3NT8 A;  3S6S A;  1RC9 A;  3S6V A;  1QNX A;  2DDB A;  3U3U C;  4AIW A;  4P27 A;  4G2U A;  4IFA A;  2EPF A;  3U3L C;  3Q2R A;  4NUK A;  4H0A A;  5JYS A;  1XTA A;  3MZ8 A;  1CFE A;  3U3N C;  2GIZ A; 
#chains in the Genus database with same CATH homology
 4D53 A;  1U53 A;  4TPV A;  3S6U A;  2VZN A;  3Q2U A;  1XX5 A;  4NUO A;  4NUI A;  5ETE A;  2DDA A;  1SMB A;  1WVR A;  4NUN A;  4LY5 A;  3NT8 A;  3S6S A;  1RC9 A;  3S6V A;  1QNX A;  2DDB A;  3U3U C;  4AIW A;  4P27 A;  4G2U A;  4IFA A;  2EPF A;  3U3L C;  3Q2R A;  4NUK A;  4H0A A;  5JYS A;  1XTA A;  3MZ8 A;  1CFE A;  3U3N C;  2GIZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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