4TPVA

Crystal structure of hookworm platelet inhibitor
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
182
structure length
182
Chain Sequence
DYSLCQQREKLDDDMREMFTELHNGYRAAFARNYKTSKMRTMVYDCTLEEKAYKSAEKCSEEPSSEEENVDVFSAATLNIPLEAGNSWWSEIFELRGKVYNKNGKTSNIANMVWDSHDKLGCAVVDCSGKTHVVCQYGPEAKGDGKTIYEEGAPCSRCSDYGAGVTCDDDWQNLLCIGHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of hookworm platelet inhibitor (HPI), a CAP superfamily member from Ancylostoma caninum.
pubmed doi rcsb
molecule keywords Platelet inhibitor
molecule tags Blood clotting
source organism Ancylostoma caninum
total genus 65
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00188 CAP Cysteine-rich secretory protein family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.33.10 Alpha Beta 3-Layer(aba) Sandwich Pathogenesis-related Protein p14a CAP 4tpvA00
4NUKA 1CFEA 3Q2UA 1RC9A 4NUIA 4H0AA 5JYSA 3U3NC 4G2UA 3U3UC 1U53A 2GIZA 4D53A 2DDBA 2EPFA 4AIWA 3S6UA 3U3LC 2VZNA 3NT8A 4IFAA 3MZ8A 4P27A 3S6VA 4NUNA 1XX5A 4TPVA 3S6SA 4NUOA 3Q2RA 5ETEA 1WVRA 1QNXA 1SMBA 2DDAA 1XTAA 4LY5A
chains in the Genus database with same CATH superfamily
4NUKA 1CFEA 3Q2UA 1RC9A 4NUIA 4H0AA 5JYSA 3U3NC 4G2UA 3U3UC 1U53A 2GIZA 4D53A 2DDBA 2EPFA 4AIWA 3S6UA 3U3LC 2VZNA 3NT8A 4IFAA 3MZ8A 4P27A 3S6VA 4NUNA 1XX5A 4TPVA 3S6SA 4NUOA 3Q2RA 5ETEA 1WVRA 1QNXA 1SMBA 2DDAA 1XTAA 4LY5A
chains in the Genus database with same CATH topology
4NUKA 1CFEA 3Q2UA 1RC9A 4NUIA 4H0AA 5JYSA 3U3NC 4G2UA 3U3UC 1U53A 2GIZA 4D53A 2DDBA 2EPFA 4AIWA 3S6UA 3U3LC 2VZNA 3NT8A 4IFAA 3MZ8A 4P27A 3S6VA 4NUNA 1XX5A 4TPVA 3S6SA 4NUOA 3Q2RA 5ETEA 1WVRA 1QNXA 1SMBA 2DDAA 1XTAA 4LY5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NUK A;  1CFE A;  3Q2U A;  1RC9 A;  4NUI A;  4H0A A;  5JYS A;  3U3N C;  4G2U A;  3U3U C;  1U53 A;  2GIZ A;  4D53 A;  2DDB A;  2EPF A;  4AIW A;  3S6U A;  3U3L C;  2VZN A;  3NT8 A;  4IFA A;  3MZ8 A;  4P27 A;  3S6V A;  4NUN A;  1XX5 A;  4TPV A;  3S6S A;  4NUO A;  3Q2R A;  5ETE A;  1WVR A;  1QNX A;  1SMB A;  2DDA A;  1XTA A;  4LY5 A; 
#chains in the Genus database with same CATH topology
 4NUK A;  1CFE A;  3Q2U A;  1RC9 A;  4NUI A;  4H0A A;  5JYS A;  3U3N C;  4G2U A;  3U3U C;  1U53 A;  2GIZ A;  4D53 A;  2DDB A;  2EPF A;  4AIW A;  3S6U A;  3U3L C;  2VZN A;  3NT8 A;  4IFA A;  3MZ8 A;  4P27 A;  3S6V A;  4NUN A;  1XX5 A;  4TPV A;  3S6S A;  4NUO A;  3Q2R A;  5ETE A;  1WVR A;  1QNX A;  1SMB A;  2DDA A;  1XTA A;  4LY5 A; 
#chains in the Genus database with same CATH homology
 4NUK A;  1CFE A;  3Q2U A;  1RC9 A;  4NUI A;  4H0A A;  5JYS A;  3U3N C;  4G2U A;  3U3U C;  1U53 A;  2GIZ A;  4D53 A;  2DDB A;  2EPF A;  4AIW A;  3S6U A;  3U3L C;  2VZN A;  3NT8 A;  4IFA A;  3MZ8 A;  4P27 A;  3S6V A;  4NUN A;  1XX5 A;  4TPV A;  3S6S A;  4NUO A;  3Q2R A;  5ETE A;  1WVR A;  1QNX A;  1SMB A;  2DDA A;  1XTA A;  4LY5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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