4TPVA

Crystal structure of hookworm platelet inhibitor
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
182
structure length
182
Chain Sequence
DYSLCQQREKLDDDMREMFTELHNGYRAAFARNYKTSKMRTMVYDCTLEEKAYKSAEKCSEEPSSEEENVDVFSAATLNIPLEAGNSWWSEIFELRGKVYNKNGKTSNIANMVWDSHDKLGCAVVDCSGKTHVVCQYGPEAKGDGKTIYEEGAPCSRCSDYGAGVTCDDDWQNLLCIGHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
source organism Ancylostoma caninum
publication title The structure of hookworm platelet inhibitor (HPI), a CAP superfamily member from Ancylostoma caninum.
pubmed doi rcsb
molecule keywords Platelet inhibitor
total genus 65
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00188 CAP Cysteine-rich secretory protein family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.33.10 Alpha Beta 3-Layer(aba) Sandwich Pathogenesis-related Protein p14a CAP 4tpvA00
3S6UA 5ETEA 3U3LC 3Q2RA 3S6SA 4LY5A 4AIWA 3Q2UA 5JYSA 2GIZA 4NUIA 2EPFA 1U53A 4P27A 4TPVA 2DDAA 4D53A 1SMBA 3U3NC 4IFAA 3S6VA 1CFEA 1QNXA 4NUKA 3U3UC 3NT8A 4G2UA 1RC9A 2VZNA 3MZ8A 4NUOA 1XX5A 2DDBA 4NUNA 1WVRA 1XTAA 4H0AA
chains in the Genus database with same CATH superfamily
3S6UA 5ETEA 3U3LC 3Q2RA 3S6SA 4LY5A 4AIWA 3Q2UA 5JYSA 2GIZA 4NUIA 2EPFA 1U53A 4P27A 4TPVA 2DDAA 4D53A 1SMBA 3U3NC 4IFAA 3S6VA 1CFEA 1QNXA 4NUKA 3U3UC 3NT8A 4G2UA 1RC9A 2VZNA 3MZ8A 4NUOA 1XX5A 2DDBA 4NUNA 1WVRA 1XTAA 4H0AA
chains in the Genus database with same CATH topology
3S6UA 5ETEA 3U3LC 3Q2RA 3S6SA 4LY5A 4AIWA 3Q2UA 5JYSA 2GIZA 4NUIA 2EPFA 1U53A 4P27A 4TPVA 2DDAA 4D53A 1SMBA 3U3NC 4IFAA 3S6VA 1CFEA 1QNXA 4NUKA 3U3UC 3NT8A 4G2UA 1RC9A 2VZNA 3MZ8A 4NUOA 1XX5A 2DDBA 4NUNA 1WVRA 1XTAA 4H0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S6U A;  5ETE A;  3U3L C;  3Q2R A;  3S6S A;  4LY5 A;  4AIW A;  3Q2U A;  5JYS A;  2GIZ A;  4NUI A;  2EPF A;  1U53 A;  4P27 A;  4TPV A;  2DDA A;  4D53 A;  1SMB A;  3U3N C;  4IFA A;  3S6V A;  1CFE A;  1QNX A;  4NUK A;  3U3U C;  3NT8 A;  4G2U A;  1RC9 A;  2VZN A;  3MZ8 A;  4NUO A;  1XX5 A;  2DDB A;  4NUN A;  1WVR A;  1XTA A;  4H0A A; 
#chains in the Genus database with same CATH topology
 3S6U A;  5ETE A;  3U3L C;  3Q2R A;  3S6S A;  4LY5 A;  4AIW A;  3Q2U A;  5JYS A;  2GIZ A;  4NUI A;  2EPF A;  1U53 A;  4P27 A;  4TPV A;  2DDA A;  4D53 A;  1SMB A;  3U3N C;  4IFA A;  3S6V A;  1CFE A;  1QNX A;  4NUK A;  3U3U C;  3NT8 A;  4G2U A;  1RC9 A;  2VZN A;  3MZ8 A;  4NUO A;  1XX5 A;  2DDB A;  4NUN A;  1WVR A;  1XTA A;  4H0A A; 
#chains in the Genus database with same CATH homology
 3S6U A;  5ETE A;  3U3L C;  3Q2R A;  3S6S A;  4LY5 A;  4AIW A;  3Q2U A;  5JYS A;  2GIZ A;  4NUI A;  2EPF A;  1U53 A;  4P27 A;  4TPV A;  2DDA A;  4D53 A;  1SMB A;  3U3N C;  4IFA A;  3S6V A;  1CFE A;  1QNX A;  4NUK A;  3U3U C;  3NT8 A;  4G2U A;  1RC9 A;  2VZN A;  3MZ8 A;  4NUO A;  1XX5 A;  2DDB A;  4NUN A;  1WVR A;  1XTA A;  4H0A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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