4YTGA

Crystal structure of porphyromonas gingivalis peptidylarginine deiminase (ppad) mutant c351a in complex with dipeptide met-arg.
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
420
structure length
417
Chain Sequence
AFQETNPPAGPVRAIAEYERSAAVLVRYPFGIPMELIKELAKNDKVITIVASESQKNTVITQYTQSGVNLSNCDFIIAKTDSYWTRDYTGWFAMYDTNKVGLVDFIYNRPRPNDDEFPKYEAQYLGIEMFGMKLKQTGGNYMTDGYGSAVQSHIAYTENSSLSQAQVNQKMKDYLGITHHDVVQDPNGEYINHVDCWGKYLAPNKILIRKVPDNHPQHQALEDMAAYFAAQTCAWGTKYEVYRALATNEQPYTNSLILNNRVFVPVNGPASVDNDALNVYKTAMPGYEIIGVKGASGTPWLGTDALHARTHEVADKGYLYIKHYPILGEQDYKIEADVVSCANATISPVQCYYRINGSGSFKAADMTMESTGHYTYSFTGLNKNDKVEYYISAADNSGRKETYPFIGEPDPFKFTCM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Porphyromonas gingivalis (strain atcc baa-308 / w83)
molecule keywords Peptidylarginine deiminase
total genus 137
structure length 417
sequence length 420
ec nomenclature ec 3.5.3.-:
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04371 PAD_porph Porphyromonas-type peptidyl-arginine deiminase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 4ytgA01
8JDWA 4N2NA 2EWOA 4N2IA 3I2EA 2JERA 2ABRA 1XKNA 3JDWA 4E4JA 4N2HA 3RHYA 5JDWA 2DEYX 4N2DA 4N2AA 5HP5A 1S9RA 3APNA 3I4AA 4YT9A 4N25A 5AK7A 2Q3UA 5AK8A 2JDXA 7JDWA 2DEXX 5M3QA 4N28A 4X8CA 4YTGA 3P8EA 4JDWA 2C6ZA 3B1TA 1JDWA 4X8GA 3H7KA 1ZBRA 2CI3A 2CMUA 3H7CX 3HVMA 1JDXA 4DKTA 2A9GA 4YTBA 1BWDA 1WD8A 4N20A 2JAIA 1H70A 3B1UA 4N24A 1WD9A 4N2BA 4N26A 2CI5A 2CI4A 9JDWA 2DW5A 3APMA 4N2KA 4N2GA 1WDAA 4BOFA 4N2LA 5AN9I 2AAFA 4N2EA 4N2CA 3P8PA 2CI7A 1VKPA 2DEWX 2ACIA 1LXYA 1G62A 4N2FA 2CI6A 3BPBA 4N22A 2JAJA 1G61A 2JDWA 1RXXA 2CI1A 4N2MA 6JDWA
chains in the Genus database with same CATH superfamily
8JDWA 4N2NA 2EWOA 4N2IA 3I2EA 2JERA 2ABRA 1XKNA 3JDWA 4E4JA 4N2HA 3RHYA 5JDWA 2DEYX 4N2DA 4N2AA 5HP5A 1S9RA 3APNA 3I4AA 4YT9A 4N25A 5AK7A 2Q3UA 5AK8A 2JDXA 7JDWA 2DEXX 5M3QA 4N28A 4X8CA 4YTGA 3P8EA 4JDWA 2C6ZA 3B1TA 1JDWA 4X8GA 3H7KA 1ZBRA 2CI3A 2CMUA 3H7CX 3HVMA 1YNHA 1JDXA 4DKTA 2A9GA 4YTBA 1BWDA 1WD8A 4N20A 2JAIA 1H70A 3B1UA 4N24A 1YNIA 1WD9A 4N2BA 4N26A 2CI5A 2CI4A 9JDWA 2DW5A 3APMA 4N2KA 4N2GA 1WDAA 4BOFA 4N2LA 5AN9I 2AAFA 4N2EA 4N2CA 3P8PA 2CI7A 1VKPA 2DEWX 2ACIA 1LXYA 1G62A 4N2FA 2CI6A 3BPBA 4N22A 2JAJA 1G61A 2JDWA 1RXXA 2CI1A 4N2MA 1YNFA 6JDWA
chains in the Genus database with same CATH topology
8JDWA 4N2NA 2EWOA 4N2IA 3I2EA 2JERA 2ABRA 1XKNA 3JDWA 4E4JA 4N2HA 3RHYA 5JDWA 2DEYX 4N2DA 4N2AA 5HP5A 1S9RA 3APNA 3I4AA 4YT9A 4N25A 5AK7A 2Q3UA 5AK8A 2JDXA 7JDWA 2DEXX 5M3QA 4N28A 4X8CA 4YTGA 3P8EA 4JDWA 2C6ZA 3B1TA 1JDWA 4X8GA 3H7KA 1ZBRA 2CI3A 2CMUA 3H7CX 3HVMA 1JDXA 4DKTA 2A9GA 4YTBA 1BWDA 1WD8A 4N20A 2JAIA 1H70A 3B1UA 4N24A 1WD9A 4N2BA 4N26A 2CI5A 2CI4A 9JDWA 2DW5A 3APMA 4N2KA 4N2GA 1WDAA 4BOFA 4N2LA 5AN9I 2AAFA 4N2EA 4N2CA 3P8PA 2CI7A 1VKPA 2DEWX 2ACIA 1LXYA 1G62A 4N2FA 2CI6A 3BPBA 4N22A 2JAJA 1G61A 2JDWA 1RXXA 2CI1A 4N2MA 6JDWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 8JDW A;  4N2N A;  2EWO A;  4N2I A;  3I2E A;  2JER A;  2ABR A;  1XKN A;  3JDW A;  4E4J A;  4N2H A;  3RHY A;  5JDW A;  2DEY X;  4N2D A;  4N2A A;  5HP5 A;  1S9R A;  3APN A;  3I4A A;  4YT9 A;  4N25 A;  5AK7 A;  2Q3U A;  5AK8 A;  2JDX A;  7JDW A;  2DEX X;  5M3Q A;  4N28 A;  4X8C A;  4YTG A;  3P8E A;  4JDW A;  2C6Z A;  3B1T A;  1JDW A;  4X8G A;  3H7K A;  1ZBR A;  2CI3 A;  2CMU A;  3H7C X;  3HVM A;  1JDX A;  4DKT A;  2A9G A;  4YTB A;  1BWD A;  1WD8 A;  4N20 A;  2JAI A;  1H70 A;  3B1U A;  4N24 A;  1WD9 A;  4N2B A;  4N26 A;  2CI5 A;  2CI4 A;  9JDW A;  2DW5 A;  3APM A;  4N2K A;  4N2G A;  1WDA A;  4BOF A;  4N2L A;  5AN9 I;  2AAF A;  4N2E A;  4N2C A;  3P8P A;  2CI7 A;  1VKP A;  2DEW X;  2ACI A;  1LXY A;  1G62 A;  4N2F A;  2CI6 A;  3BPB A;  4N22 A;  2JAJ A;  1G61 A;  2JDW A;  1RXX A;  2CI1 A;  4N2M A;  6JDW A; 
#chains in the Genus database with same CATH topology
 8JDW A;  4N2N A;  2EWO A;  4N2I A;  3I2E A;  2JER A;  2ABR A;  1XKN A;  3JDW A;  4E4J A;  4N2H A;  3RHY A;  5JDW A;  2DEY X;  4N2D A;  4N2A A;  5HP5 A;  1S9R A;  3APN A;  3I4A A;  4YT9 A;  4N25 A;  5AK7 A;  2Q3U A;  5AK8 A;  2JDX A;  7JDW A;  2DEX X;  5M3Q A;  4N28 A;  4X8C A;  4YTG A;  3P8E A;  4JDW A;  2C6Z A;  3B1T A;  1JDW A;  4X8G A;  3H7K A;  1ZBR A;  2CI3 A;  2CMU A;  3H7C X;  3HVM A;  1YNH A;  1JDX A;  4DKT A;  2A9G A;  4YTB A;  1BWD A;  1WD8 A;  4N20 A;  2JAI A;  1H70 A;  3B1U A;  4N24 A;  1YNI A;  1WD9 A;  4N2B A;  4N26 A;  2CI5 A;  2CI4 A;  9JDW A;  2DW5 A;  3APM A;  4N2K A;  4N2G A;  1WDA A;  4BOF A;  4N2L A;  5AN9 I;  2AAF A;  4N2E A;  4N2C A;  3P8P A;  2CI7 A;  1VKP A;  2DEW X;  2ACI A;  1LXY A;  1G62 A;  4N2F A;  2CI6 A;  3BPB A;  4N22 A;  2JAJ A;  1G61 A;  2JDW A;  1RXX A;  2CI1 A;  4N2M A;  1YNF A;  6JDW A; 
#chains in the Genus database with same CATH homology
 8JDW A;  4N2N A;  2EWO A;  4N2I A;  3I2E A;  2JER A;  2ABR A;  1XKN A;  3JDW A;  4E4J A;  4N2H A;  3RHY A;  5JDW A;  2DEY X;  4N2D A;  4N2A A;  5HP5 A;  1S9R A;  3APN A;  3I4A A;  4YT9 A;  4N25 A;  5AK7 A;  2Q3U A;  5AK8 A;  2JDX A;  7JDW A;  2DEX X;  5M3Q A;  4N28 A;  4X8C A;  4YTG A;  3P8E A;  4JDW A;  2C6Z A;  3B1T A;  1JDW A;  4X8G A;  3H7K A;  1ZBR A;  2CI3 A;  2CMU A;  3H7C X;  3HVM A;  1JDX A;  4DKT A;  2A9G A;  4YTB A;  1BWD A;  1WD8 A;  4N20 A;  2JAI A;  1H70 A;  3B1U A;  4N24 A;  1WD9 A;  4N2B A;  4N26 A;  2CI5 A;  2CI4 A;  9JDW A;  2DW5 A;  3APM A;  4N2K A;  4N2G A;  1WDA A;  4BOF A;  4N2L A;  5AN9 I;  2AAF A;  4N2E A;  4N2C A;  3P8P A;  2CI7 A;  1VKP A;  2DEW X;  2ACI A;  1LXY A;  1G62 A;  4N2F A;  2CI6 A;  3BPB A;  4N22 A;  2JAJ A;  1G61 A;  2JDW A;  1RXX A;  2CI1 A;  4N2M A;  6JDW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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