4JDWA

Crystal structure and mechanism of l-arginine: glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHAWTCDVRRRGTLQSYLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords L-ARGININE\:GLYCINE AMIDINOTRANSFERASE
total genus 119
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1997-01-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 4jdwA00
2ACIA 2JDWA 2CI5A 3B1UA 4N20A 4YTGA 4N25A 2JERA 2DEYX 1XKNA 3RHYA 1G61A 6JDWA 5AK8A 3B1TA 1ZBRA 4N2DA 1WDAA 4N2NA 3APNA 2CI3A 4N2CA 1JDWA 5HP5A 1VKPA 2JAJA 2JDXA 1BWDA 4N2HA 2Q3UA 2CI1A 2C6ZA 4N22A 4X8CA 1WD9A 5AK7A 1LXYA 4X8GA 5AN9I 9JDWA 4N2IA 4N2EA 2AAFA 2DEWX 5JDWA 1RXXA 3H7CX 4N28A 2CI4A 2JAIA 7JDWA 2DW5A 5M3QA 4BOFA 1G62A 3H7KA 2EWOA 1H70A 4DKTA 4N2MA 3BPBA 3I4AA 3I2EA 2ABRA 3APMA 4N2AA 4N2FA 3HVMA 1WD8A 4JDWA 4N26A 4YT9A 4N24A 2A9GA 3P8EA 1JDXA 4YTBA 2CI6A 2DEXX 3P8PA 2CI7A 8JDWA 4N2GA 2CMUA 3JDWA 4N2BA 4N2LA 4N2KA 4E4JA 1S9RA
chains in the Genus database with same CATH superfamily
2ACIA 2JDWA 2CI5A 3B1UA 4N20A 1YNIA 4YTGA 4N25A 2JERA 2DEYX 1XKNA 3RHYA 1G61A 6JDWA 5AK8A 3B1TA 1ZBRA 4N2DA 1WDAA 4N2NA 3APNA 2CI3A 4N2CA 1JDWA 5HP5A 1VKPA 2JAJA 2JDXA 1BWDA 4N2HA 2Q3UA 2CI1A 2C6ZA 4N22A 4X8CA 1WD9A 5AK7A 1LXYA 4X8GA 5AN9I 9JDWA 1YNFA 4N2IA 4N2EA 2AAFA 2DEWX 5JDWA 1RXXA 3H7CX 4N28A 2CI4A 2JAIA 1YNHA 7JDWA 2DW5A 5M3QA 4BOFA 1G62A 3H7KA 2EWOA 1H70A 4DKTA 4N2MA 3BPBA 3I4AA 3I2EA 2ABRA 3APMA 4N2AA 4N2FA 3HVMA 1WD8A 4JDWA 4N26A 4YT9A 4N24A 2A9GA 3P8EA 1JDXA 4YTBA 2CI6A 2DEXX 3P8PA 2CI7A 8JDWA 4N2GA 2CMUA 3JDWA 4N2BA 4N2LA 4N2KA 4E4JA 1S9RA
chains in the Genus database with same CATH topology
2ACIA 2JDWA 2CI5A 3B1UA 4N20A 4YTGA 4N25A 2JERA 2DEYX 1XKNA 3RHYA 1G61A 6JDWA 5AK8A 3B1TA 1ZBRA 4N2DA 1WDAA 4N2NA 3APNA 2CI3A 4N2CA 1JDWA 5HP5A 1VKPA 2JAJA 2JDXA 1BWDA 4N2HA 2Q3UA 2CI1A 2C6ZA 4N22A 4X8CA 1WD9A 5AK7A 1LXYA 4X8GA 5AN9I 9JDWA 4N2IA 4N2EA 2AAFA 2DEWX 5JDWA 1RXXA 3H7CX 4N28A 2CI4A 2JAIA 7JDWA 2DW5A 5M3QA 4BOFA 1G62A 3H7KA 2EWOA 1H70A 4DKTA 4N2MA 3BPBA 3I4AA 3I2EA 2ABRA 3APMA 4N2AA 4N2FA 3HVMA 1WD8A 4JDWA 4N26A 4YT9A 4N24A 2A9GA 3P8EA 1JDXA 4YTBA 2CI6A 2DEXX 3P8PA 2CI7A 8JDWA 4N2GA 2CMUA 3JDWA 4N2BA 4N2LA 4N2KA 4E4JA 1S9RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ACI A;  2JDW A;  2CI5 A;  3B1U A;  4N20 A;  4YTG A;  4N25 A;  2JER A;  2DEY X;  1XKN A;  3RHY A;  1G61 A;  6JDW A;  5AK8 A;  3B1T A;  1ZBR A;  4N2D A;  1WDA A;  4N2N A;  3APN A;  2CI3 A;  4N2C A;  1JDW A;  5HP5 A;  1VKP A;  2JAJ A;  2JDX A;  1BWD A;  4N2H A;  2Q3U A;  2CI1 A;  2C6Z A;  4N22 A;  4X8C A;  1WD9 A;  5AK7 A;  1LXY A;  4X8G A;  5AN9 I;  9JDW A;  4N2I A;  4N2E A;  2AAF A;  2DEW X;  5JDW A;  1RXX A;  3H7C X;  4N28 A;  2CI4 A;  2JAI A;  7JDW A;  2DW5 A;  5M3Q A;  4BOF A;  1G62 A;  3H7K A;  2EWO A;  1H70 A;  4DKT A;  4N2M A;  3BPB A;  3I4A A;  3I2E A;  2ABR A;  3APM A;  4N2A A;  4N2F A;  3HVM A;  1WD8 A;  4JDW A;  4N26 A;  4YT9 A;  4N24 A;  2A9G A;  3P8E A;  1JDX A;  4YTB A;  2CI6 A;  2DEX X;  3P8P A;  2CI7 A;  8JDW A;  4N2G A;  2CMU A;  3JDW A;  4N2B A;  4N2L A;  4N2K A;  4E4J A;  1S9R A; 
#chains in the Genus database with same CATH topology
 2ACI A;  2JDW A;  2CI5 A;  3B1U A;  4N20 A;  1YNI A;  4YTG A;  4N25 A;  2JER A;  2DEY X;  1XKN A;  3RHY A;  1G61 A;  6JDW A;  5AK8 A;  3B1T A;  1ZBR A;  4N2D A;  1WDA A;  4N2N A;  3APN A;  2CI3 A;  4N2C A;  1JDW A;  5HP5 A;  1VKP A;  2JAJ A;  2JDX A;  1BWD A;  4N2H A;  2Q3U A;  2CI1 A;  2C6Z A;  4N22 A;  4X8C A;  1WD9 A;  5AK7 A;  1LXY A;  4X8G A;  5AN9 I;  9JDW A;  1YNF A;  4N2I A;  4N2E A;  2AAF A;  2DEW X;  5JDW A;  1RXX A;  3H7C X;  4N28 A;  2CI4 A;  2JAI A;  1YNH A;  7JDW A;  2DW5 A;  5M3Q A;  4BOF A;  1G62 A;  3H7K A;  2EWO A;  1H70 A;  4DKT A;  4N2M A;  3BPB A;  3I4A A;  3I2E A;  2ABR A;  3APM A;  4N2A A;  4N2F A;  3HVM A;  1WD8 A;  4JDW A;  4N26 A;  4YT9 A;  4N24 A;  2A9G A;  3P8E A;  1JDX A;  4YTB A;  2CI6 A;  2DEX X;  3P8P A;  2CI7 A;  8JDW A;  4N2G A;  2CMU A;  3JDW A;  4N2B A;  4N2L A;  4N2K A;  4E4J A;  1S9R A; 
#chains in the Genus database with same CATH homology
 2ACI A;  2JDW A;  2CI5 A;  3B1U A;  4N20 A;  4YTG A;  4N25 A;  2JER A;  2DEY X;  1XKN A;  3RHY A;  1G61 A;  6JDW A;  5AK8 A;  3B1T A;  1ZBR A;  4N2D A;  1WDA A;  4N2N A;  3APN A;  2CI3 A;  4N2C A;  1JDW A;  5HP5 A;  1VKP A;  2JAJ A;  2JDX A;  1BWD A;  4N2H A;  2Q3U A;  2CI1 A;  2C6Z A;  4N22 A;  4X8C A;  1WD9 A;  5AK7 A;  1LXY A;  4X8G A;  5AN9 I;  9JDW A;  4N2I A;  4N2E A;  2AAF A;  2DEW X;  5JDW A;  1RXX A;  3H7C X;  4N28 A;  2CI4 A;  2JAI A;  7JDW A;  2DW5 A;  5M3Q A;  4BOF A;  1G62 A;  3H7K A;  2EWO A;  1H70 A;  4DKT A;  4N2M A;  3BPB A;  3I4A A;  3I2E A;  2ABR A;  3APM A;  4N2A A;  4N2F A;  3HVM A;  1WD8 A;  4JDW A;  4N26 A;  4YT9 A;  4N24 A;  2A9G A;  3P8E A;  1JDX A;  4YTB A;  2CI6 A;  2DEX X;  3P8P A;  2CI7 A;  8JDW A;  4N2G A;  2CMU A;  3JDW A;  4N2B A;  4N2L A;  4N2K A;  4E4J A;  1S9R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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