5AN9I

Mechanism of eif6 release from the nascent 60s ribosomal subunit
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
224
structure length
224
Chain Sequence
MATRLQYENSCDVGVFLKLTNKYCLVGQCGSKQFLHTVENRLADHIPVVETSIAGTRIVGRLSAGNKNGLLLPNTCTDQELQQIRNSLPDDVVVQRIEEKFSALGNCIATNDYVALVHPDIDRETEEIIADVLGVEVFRQTVSGNVLVGTYCALTNQGALVHPMTSIADQDELSSLLQVPLVAGTVNRGNECVAAGCVVNDWTAIVGADTTATEISVIESIFAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Eif6 Release from the Nascent 60S Ribosomal Subunit
pubmed doi rcsb
molecule tags Translation
source organism Homo sapiens
molecule keywords 60S RIBOSOMAL PROTEIN L3
total genus 42
structure length 224
sequence length 224
ec nomenclature
pdb deposition date 2015-09-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF01912 eIF-6 eIF-6 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 5an9I00
4BOFA 1WD9A 2AAFA 4N24A 2DEWX 4JDWA 2CI6A 2CI7A 1WD8A 4N2MA 3RHYA 4YTGA 2DEXX 2DEYX 9JDWA 4X8CA 5JDWA 1S9RA 4N26A 1JDWA 3JDWA 1BWDA 3B1UA 5AK8A 1XKNA 2JAIA 4N2GA 7JDWA 1JDXA 4N2DA 4X8GA 8JDWA 2C6ZA 4N22A 4N28A 3BPBA 5HP5A 3H7KA 3B1TA 3P8EA 2A9GA 2CMUA 4N2FA 4N25A 4N2HA 4YT9A 2CI3A 2ACIA 4N2EA 4N2BA 1LXYA 2JAJA 4YTBA 4N2LA 1VKPA 3I2EA 3I4AA 4N2NA 4N2AA 2JDXA 4N20A 2ABRA 4N2KA 5AN9I 3P8PA 1ZBRA 6JDWA 3H7CX 1G62A 1G61A 2Q3UA 3HVMA 4E4JA 2JERA 4DKTA 2EWOA 2CI4A 1WDAA 5AK7A 3APNA 5M3QA 1RXXA 3APMA 1H70A 2CI5A 4N2IA 2JDWA 4N2CA 2CI1A 2DW5A
chains in the Genus database with same CATH superfamily
4BOFA 1WD9A 2AAFA 4N24A 2DEWX 4JDWA 2CI6A 2CI7A 1WD8A 4N2MA 3RHYA 4YTGA 2DEXX 2DEYX 9JDWA 4X8CA 5JDWA 1S9RA 4N26A 1JDWA 3JDWA 1BWDA 3B1UA 5AK8A 1XKNA 2JAIA 4N2GA 7JDWA 1JDXA 4N2DA 1YNFA 4X8GA 8JDWA 2C6ZA 4N22A 4N28A 3BPBA 5HP5A 3H7KA 3B1TA 3P8EA 2A9GA 2CMUA 4N2FA 4N25A 4N2HA 4YT9A 2CI3A 2ACIA 4N2EA 4N2BA 1LXYA 2JAJA 4YTBA 4N2LA 1VKPA 3I2EA 3I4AA 4N2NA 4N2AA 2JDXA 1YNHA 4N20A 2ABRA 4N2KA 5AN9I 3P8PA 1ZBRA 6JDWA 3H7CX 1G62A 1G61A 2Q3UA 1YNIA 3HVMA 4E4JA 2JERA 4DKTA 2EWOA 2CI4A 1WDAA 5AK7A 3APNA 5M3QA 1RXXA 3APMA 1H70A 2CI5A 4N2IA 2JDWA 4N2CA 2CI1A 2DW5A
chains in the Genus database with same CATH topology
4BOFA 1WD9A 2AAFA 4N24A 2DEWX 4JDWA 2CI6A 2CI7A 1WD8A 4N2MA 3RHYA 4YTGA 2DEXX 2DEYX 9JDWA 4X8CA 5JDWA 1S9RA 4N26A 1JDWA 3JDWA 1BWDA 3B1UA 5AK8A 1XKNA 2JAIA 4N2GA 7JDWA 1JDXA 4N2DA 4X8GA 8JDWA 2C6ZA 4N22A 4N28A 3BPBA 5HP5A 3H7KA 3B1TA 3P8EA 2A9GA 2CMUA 4N2FA 4N25A 4N2HA 4YT9A 2CI3A 2ACIA 4N2EA 4N2BA 1LXYA 2JAJA 4YTBA 4N2LA 1VKPA 3I2EA 3I4AA 4N2NA 4N2AA 2JDXA 4N20A 2ABRA 4N2KA 5AN9I 3P8PA 1ZBRA 6JDWA 3H7CX 1G62A 1G61A 2Q3UA 3HVMA 4E4JA 2JERA 4DKTA 2EWOA 2CI4A 1WDAA 5AK7A 3APNA 5M3QA 1RXXA 3APMA 1H70A 2CI5A 4N2IA 2JDWA 4N2CA 2CI1A 2DW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BOF A;  1WD9 A;  2AAF A;  4N24 A;  2DEW X;  4JDW A;  2CI6 A;  2CI7 A;  1WD8 A;  4N2M A;  3RHY A;  4YTG A;  2DEX X;  2DEY X;  9JDW A;  4X8C A;  5JDW A;  1S9R A;  4N26 A;  1JDW A;  3JDW A;  1BWD A;  3B1U A;  5AK8 A;  1XKN A;  2JAI A;  4N2G A;  7JDW A;  1JDX A;  4N2D A;  4X8G A;  8JDW A;  2C6Z A;  4N22 A;  4N28 A;  3BPB A;  5HP5 A;  3H7K A;  3B1T A;  3P8E A;  2A9G A;  2CMU A;  4N2F A;  4N25 A;  4N2H A;  4YT9 A;  2CI3 A;  2ACI A;  4N2E A;  4N2B A;  1LXY A;  2JAJ A;  4YTB A;  4N2L A;  1VKP A;  3I2E A;  3I4A A;  4N2N A;  4N2A A;  2JDX A;  4N20 A;  2ABR A;  4N2K A;  5AN9 I;  3P8P A;  1ZBR A;  6JDW A;  3H7C X;  1G62 A;  1G61 A;  2Q3U A;  3HVM A;  4E4J A;  2JER A;  4DKT A;  2EWO A;  2CI4 A;  1WDA A;  5AK7 A;  3APN A;  5M3Q A;  1RXX A;  3APM A;  1H70 A;  2CI5 A;  4N2I A;  2JDW A;  4N2C A;  2CI1 A;  2DW5 A; 
#chains in the Genus database with same CATH topology
 4BOF A;  1WD9 A;  2AAF A;  4N24 A;  2DEW X;  4JDW A;  2CI6 A;  2CI7 A;  1WD8 A;  4N2M A;  3RHY A;  4YTG A;  2DEX X;  2DEY X;  9JDW A;  4X8C A;  5JDW A;  1S9R A;  4N26 A;  1JDW A;  3JDW A;  1BWD A;  3B1U A;  5AK8 A;  1XKN A;  2JAI A;  4N2G A;  7JDW A;  1JDX A;  4N2D A;  1YNF A;  4X8G A;  8JDW A;  2C6Z A;  4N22 A;  4N28 A;  3BPB A;  5HP5 A;  3H7K A;  3B1T A;  3P8E A;  2A9G A;  2CMU A;  4N2F A;  4N25 A;  4N2H A;  4YT9 A;  2CI3 A;  2ACI A;  4N2E A;  4N2B A;  1LXY A;  2JAJ A;  4YTB A;  4N2L A;  1VKP A;  3I2E A;  3I4A A;  4N2N A;  4N2A A;  2JDX A;  1YNH A;  4N20 A;  2ABR A;  4N2K A;  5AN9 I;  3P8P A;  1ZBR A;  6JDW A;  3H7C X;  1G62 A;  1G61 A;  2Q3U A;  1YNI A;  3HVM A;  4E4J A;  2JER A;  4DKT A;  2EWO A;  2CI4 A;  1WDA A;  5AK7 A;  3APN A;  5M3Q A;  1RXX A;  3APM A;  1H70 A;  2CI5 A;  4N2I A;  2JDW A;  4N2C A;  2CI1 A;  2DW5 A; 
#chains in the Genus database with same CATH homology
 4BOF A;  1WD9 A;  2AAF A;  4N24 A;  2DEW X;  4JDW A;  2CI6 A;  2CI7 A;  1WD8 A;  4N2M A;  3RHY A;  4YTG A;  2DEX X;  2DEY X;  9JDW A;  4X8C A;  5JDW A;  1S9R A;  4N26 A;  1JDW A;  3JDW A;  1BWD A;  3B1U A;  5AK8 A;  1XKN A;  2JAI A;  4N2G A;  7JDW A;  1JDX A;  4N2D A;  4X8G A;  8JDW A;  2C6Z A;  4N22 A;  4N28 A;  3BPB A;  5HP5 A;  3H7K A;  3B1T A;  3P8E A;  2A9G A;  2CMU A;  4N2F A;  4N25 A;  4N2H A;  4YT9 A;  2CI3 A;  2ACI A;  4N2E A;  4N2B A;  1LXY A;  2JAJ A;  4YTB A;  4N2L A;  1VKP A;  3I2E A;  3I4A A;  4N2N A;  4N2A A;  2JDX A;  4N20 A;  2ABR A;  4N2K A;  5AN9 I;  3P8P A;  1ZBR A;  6JDW A;  3H7C X;  1G62 A;  1G61 A;  2Q3U A;  3HVM A;  4E4J A;  2JER A;  4DKT A;  2EWO A;  2CI4 A;  1WDA A;  5AK7 A;  3APN A;  5M3Q A;  1RXX A;  3APM A;  1H70 A;  2CI5 A;  4N2I A;  2JDW A;  4N2C A;  2CI1 A;  2DW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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