5JXZA

A low magnesium structure of the isochorismate synthase, entc
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
376
structure length
373
Chain Sequence
TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASATRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
pubmed doi rcsb
molecule tags Isomerase
source organism Escherichia coli o157:h7
molecule keywords Isochorismate synthase EntC
total genus 115
structure length 373
sequence length 376
chains with identical sequence B
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2016-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 5jxzA00
3OS6A 3GSEA 3HWOA 3BZMA 3R76A 3BZNA 3R75A 2FN1A 1QDLA 5JY4A 3LOGA 3RV9A 2EUAA 5KCKA 4GRHA 5JXZA 1I7SA 1K0GA 3R74A 5JZDA 5JY9A 3VEHA 2G5FA 1I7QA 1I1QA 2I6YA 5JY8A 1K0EA 5CWAA 3RV7A 3RV6A 5JY4B 2FN0A 3ST6A 3H9MA 3RV8A
chains in the Genus database with same CATH superfamily
3OS6A 3GSEA 3HWOA 3BZMA 3R76A 3BZNA 3R75A 2FN1A 1QDLA 5JY4A 3LOGA 3RV9A 2EUAA 5KCKA 4GRHA 5JXZA 1I7SA 1K0GA 3R74A 5JZDA 5JY9A 3VEHA 2G5FA 1I7QA 1I1QA 2I6YA 5JY8A 1K0EA 5CWAA 3RV7A 3RV6A 5JY4B 2FN0A 3ST6A 3H9MA 3RV8A
chains in the Genus database with same CATH topology
3OS6A 3GSEA 3HWOA 3BZMA 3R76A 3BZNA 3R75A 2FN1A 1QDLA 5JY4A 3LOGA 3RV9A 2EUAA 5KCKA 4GRHA 5JXZA 1I7SA 1K0GA 3R74A 5JZDA 5JY9A 3VEHA 2G5FA 1I7QA 1I1QA 2I6YA 5JY8A 1K0EA 5CWAA 3RV7A 3RV6A 5JY4B 2FN0A 3ST6A 3H9MA 3RV8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OS6 A;  3GSE A;  3HWO A;  3BZM A;  3R76 A;  3BZN A;  3R75 A;  2FN1 A;  1QDL A;  5JY4 A;  3LOG A;  3RV9 A;  2EUA A;  5KCK A;  4GRH A;  5JXZ A;  1I7S A;  1K0G A;  3R74 A;  5JZD A;  5JY9 A;  3VEH A;  2G5F A;  1I7Q A;  1I1Q A;  2I6Y A;  5JY8 A;  1K0E A;  5CWA A;  3RV7 A;  3RV6 A;  5JY4 B;  2FN0 A;  3ST6 A;  3H9M A;  3RV8 A; 
#chains in the Genus database with same CATH topology
 3OS6 A;  3GSE A;  3HWO A;  3BZM A;  3R76 A;  3BZN A;  3R75 A;  2FN1 A;  1QDL A;  5JY4 A;  3LOG A;  3RV9 A;  2EUA A;  5KCK A;  4GRH A;  5JXZ A;  1I7S A;  1K0G A;  3R74 A;  5JZD A;  5JY9 A;  3VEH A;  2G5F A;  1I7Q A;  1I1Q A;  2I6Y A;  5JY8 A;  1K0E A;  5CWA A;  3RV7 A;  3RV6 A;  5JY4 B;  2FN0 A;  3ST6 A;  3H9M A;  3RV8 A; 
#chains in the Genus database with same CATH homology
 3OS6 A;  3GSE A;  3HWO A;  3BZM A;  3R76 A;  3BZN A;  3R75 A;  2FN1 A;  1QDL A;  5JY4 A;  3LOG A;  3RV9 A;  2EUA A;  5KCK A;  4GRH A;  5JXZ A;  1I7S A;  1K0G A;  3R74 A;  5JZD A;  5JY9 A;  3VEH A;  2G5F A;  1I7Q A;  1I1Q A;  2I6Y A;  5JY8 A;  1K0E A;  5CWA A;  3RV7 A;  3RV6 A;  5JY4 B;  2FN0 A;  3ST6 A;  3H9M A;  3RV8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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