5JY4A

A high magnesium structure of the isochorismate synthase, entc
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
375
structure length
374
Chain Sequence
TLAPNRFFFMSPYRSFTTSGFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
pubmed doi rcsb
molecule tags Isomerase
source organism Escherichia coli o157:h7
molecule keywords Isochorismate synthase EntC
total genus 116
structure length 374
sequence length 375
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2016-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 5jy4A00
1K0GA 2FN1A 3LOGA 5JY9A 3BZMA 3RV6A 2EUAA 5JZDA 1I7SA 5JY8A 3BZNA 3R76A 3RV9A 3VEHA 5KCKA 1I7QA 3GSEA 1K0EA 5JY4A 1I1QA 3RV8A 5JXZA 2FN0A 3H9MA 2G5FA 3R74A 5CWAA 3HWOA 3ST6A 3OS6A 1QDLA 3RV7A 5JY4B 2I6YA 3R75A 4GRHA
chains in the Genus database with same CATH superfamily
1K0GA 2FN1A 3LOGA 5JY9A 3BZMA 3RV6A 2EUAA 5JZDA 1I7SA 5JY8A 3BZNA 3R76A 3RV9A 3VEHA 5KCKA 1I7QA 3GSEA 1K0EA 5JY4A 1I1QA 3RV8A 5JXZA 2FN0A 3H9MA 2G5FA 3R74A 5CWAA 3HWOA 3ST6A 3OS6A 1QDLA 3RV7A 5JY4B 2I6YA 3R75A 4GRHA
chains in the Genus database with same CATH topology
1K0GA 2FN1A 3LOGA 5JY9A 3BZMA 3RV6A 2EUAA 5JZDA 1I7SA 5JY8A 3BZNA 3R76A 3RV9A 3VEHA 5KCKA 1I7QA 3GSEA 1K0EA 5JY4A 1I1QA 3RV8A 5JXZA 2FN0A 3H9MA 2G5FA 3R74A 5CWAA 3HWOA 3ST6A 3OS6A 1QDLA 3RV7A 5JY4B 2I6YA 3R75A 4GRHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K0G A;  2FN1 A;  3LOG A;  5JY9 A;  3BZM A;  3RV6 A;  2EUA A;  5JZD A;  1I7S A;  5JY8 A;  3BZN A;  3R76 A;  3RV9 A;  3VEH A;  5KCK A;  1I7Q A;  3GSE A;  1K0E A;  5JY4 A;  1I1Q A;  3RV8 A;  5JXZ A;  2FN0 A;  3H9M A;  2G5F A;  3R74 A;  5CWA A;  3HWO A;  3ST6 A;  3OS6 A;  1QDL A;  3RV7 A;  5JY4 B;  2I6Y A;  3R75 A;  4GRH A; 
#chains in the Genus database with same CATH topology
 1K0G A;  2FN1 A;  3LOG A;  5JY9 A;  3BZM A;  3RV6 A;  2EUA A;  5JZD A;  1I7S A;  5JY8 A;  3BZN A;  3R76 A;  3RV9 A;  3VEH A;  5KCK A;  1I7Q A;  3GSE A;  1K0E A;  5JY4 A;  1I1Q A;  3RV8 A;  5JXZ A;  2FN0 A;  3H9M A;  2G5F A;  3R74 A;  5CWA A;  3HWO A;  3ST6 A;  3OS6 A;  1QDL A;  3RV7 A;  5JY4 B;  2I6Y A;  3R75 A;  4GRH A; 
#chains in the Genus database with same CATH homology
 1K0G A;  2FN1 A;  3LOG A;  5JY9 A;  3BZM A;  3RV6 A;  2EUA A;  5JZD A;  1I7S A;  5JY8 A;  3BZN A;  3R76 A;  3RV9 A;  3VEH A;  5KCK A;  1I7Q A;  3GSE A;  1K0E A;  5JY4 A;  1I1Q A;  3RV8 A;  5JXZ A;  2FN0 A;  3H9M A;  2G5F A;  3R74 A;  5CWA A;  3HWO A;  3ST6 A;  3OS6 A;  1QDL A;  3RV7 A;  5JY4 B;  2I6Y A;  3R75 A;  4GRH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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