5JY4B

A high magnesium structure of the isochorismate synthase, entc
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
377
structure length
374
Chain Sequence
TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
pubmed doi rcsb
molecule keywords Isochorismate synthase EntC
molecule tags Isomerase
source organism Escherichia coli o157:h7
total genus 113
structure length 374
sequence length 377
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2016-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 5jy4B00
3R75A 1QDLA 3ST6A 5JY4A 1I7SA 5CWAA 2FN0A 3RV9A 3OS6A 1K0EA 3BZNA 4GRHA 3RV8A 2FN1A 2I6YA 5JXZA 5KCKA 5JZDA 1I7QA 3R76A 5JY8A 3BZMA 1K0GA 1I1QA 3GSEA 2G5FA 3R74A 3LOGA 3RV7A 3VEHA 5JY4B 5JY9A 3RV6A 3HWOA 2EUAA 3H9MA
chains in the Genus database with same CATH superfamily
3R75A 1QDLA 3ST6A 5JY4A 1I7SA 5CWAA 2FN0A 3RV9A 3OS6A 1K0EA 3BZNA 4GRHA 3RV8A 2FN1A 2I6YA 5JXZA 5KCKA 5JZDA 1I7QA 3R76A 5JY8A 3BZMA 1K0GA 1I1QA 3GSEA 2G5FA 3R74A 3LOGA 3RV7A 3VEHA 5JY4B 5JY9A 3RV6A 3HWOA 2EUAA 3H9MA
chains in the Genus database with same CATH topology
3R75A 1QDLA 3ST6A 5JY4A 1I7SA 5CWAA 2FN0A 3RV9A 3OS6A 1K0EA 3BZNA 4GRHA 3RV8A 2FN1A 2I6YA 5JXZA 5KCKA 5JZDA 1I7QA 3R76A 5JY8A 3BZMA 1K0GA 1I1QA 3GSEA 2G5FA 3R74A 3LOGA 3RV7A 3VEHA 5JY4B 5JY9A 3RV6A 3HWOA 2EUAA 3H9MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R75 A;  1QDL A;  3ST6 A;  5JY4 A;  1I7S A;  5CWA A;  2FN0 A;  3RV9 A;  3OS6 A;  1K0E A;  3BZN A;  4GRH A;  3RV8 A;  2FN1 A;  2I6Y A;  5JXZ A;  5KCK A;  5JZD A;  1I7Q A;  3R76 A;  5JY8 A;  3BZM A;  1K0G A;  1I1Q A;  3GSE A;  2G5F A;  3R74 A;  3LOG A;  3RV7 A;  3VEH A;  5JY4 B;  5JY9 A;  3RV6 A;  3HWO A;  2EUA A;  3H9M A; 
#chains in the Genus database with same CATH topology
 3R75 A;  1QDL A;  3ST6 A;  5JY4 A;  1I7S A;  5CWA A;  2FN0 A;  3RV9 A;  3OS6 A;  1K0E A;  3BZN A;  4GRH A;  3RV8 A;  2FN1 A;  2I6Y A;  5JXZ A;  5KCK A;  5JZD A;  1I7Q A;  3R76 A;  5JY8 A;  3BZM A;  1K0G A;  1I1Q A;  3GSE A;  2G5F A;  3R74 A;  3LOG A;  3RV7 A;  3VEH A;  5JY4 B;  5JY9 A;  3RV6 A;  3HWO A;  2EUA A;  3H9M A; 
#chains in the Genus database with same CATH homology
 3R75 A;  1QDL A;  3ST6 A;  5JY4 A;  1I7S A;  5CWA A;  2FN0 A;  3RV9 A;  3OS6 A;  1K0E A;  3BZN A;  4GRH A;  3RV8 A;  2FN1 A;  2I6Y A;  5JXZ A;  5KCK A;  5JZD A;  1I7Q A;  3R76 A;  5JY8 A;  3BZM A;  1K0G A;  1I1Q A;  3GSE A;  2G5F A;  3R74 A;  3LOG A;  3RV7 A;  3VEH A;  5JY4 B;  5JY9 A;  3RV6 A;  3HWO A;  2EUA A;  3H9M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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