5JY8A

An iron-bound structure of the isochorismate synthase entc
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
375
structure length
368
Chain Sequence
LAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASASLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
pubmed doi rcsb
molecule tags Isomerase
source organism Escherichia coli o157:h7
molecule keywords Isochorismate synthase EntC
total genus 106
structure length 368
sequence length 375
chains with identical sequence B
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2016-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 5jy8A00
3OS6A 1K0GA 3R76A 3BZMA 2EUAA 3R75A 5JY4B 3RV6A 3R74A 3ST6A 3HWOA 3VEHA 5KCKA 3BZNA 3LOGA 5CWAA 1K0EA 2G5FA 5JXZA 3GSEA 2FN1A 3RV7A 2FN0A 3H9MA 5JZDA 5JY9A 3RV8A 5JY8A 4GRHA 1I7SA 1I1QA 5JY4A 2I6YA 1I7QA 1QDLA 3RV9A
chains in the Genus database with same CATH superfamily
3OS6A 1K0GA 3R76A 3BZMA 2EUAA 3R75A 5JY4B 3RV6A 3R74A 3ST6A 3HWOA 3VEHA 5KCKA 3BZNA 3LOGA 5CWAA 1K0EA 2G5FA 5JXZA 3GSEA 2FN1A 3RV7A 2FN0A 3H9MA 5JZDA 5JY9A 3RV8A 5JY8A 4GRHA 1I7SA 1I1QA 5JY4A 2I6YA 1I7QA 1QDLA 3RV9A
chains in the Genus database with same CATH topology
3OS6A 1K0GA 3R76A 3BZMA 2EUAA 3R75A 5JY4B 3RV6A 3R74A 3ST6A 3HWOA 3VEHA 5KCKA 3BZNA 3LOGA 5CWAA 1K0EA 2G5FA 5JXZA 3GSEA 2FN1A 3RV7A 2FN0A 3H9MA 5JZDA 5JY9A 3RV8A 5JY8A 4GRHA 1I7SA 1I1QA 5JY4A 2I6YA 1I7QA 1QDLA 3RV9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OS6 A;  1K0G A;  3R76 A;  3BZM A;  2EUA A;  3R75 A;  5JY4 B;  3RV6 A;  3R74 A;  3ST6 A;  3HWO A;  3VEH A;  5KCK A;  3BZN A;  3LOG A;  5CWA A;  1K0E A;  2G5F A;  5JXZ A;  3GSE A;  2FN1 A;  3RV7 A;  2FN0 A;  3H9M A;  5JZD A;  5JY9 A;  3RV8 A;  5JY8 A;  4GRH A;  1I7S A;  1I1Q A;  5JY4 A;  2I6Y A;  1I7Q A;  1QDL A;  3RV9 A; 
#chains in the Genus database with same CATH topology
 3OS6 A;  1K0G A;  3R76 A;  3BZM A;  2EUA A;  3R75 A;  5JY4 B;  3RV6 A;  3R74 A;  3ST6 A;  3HWO A;  3VEH A;  5KCK A;  3BZN A;  3LOG A;  5CWA A;  1K0E A;  2G5F A;  5JXZ A;  3GSE A;  2FN1 A;  3RV7 A;  2FN0 A;  3H9M A;  5JZD A;  5JY9 A;  3RV8 A;  5JY8 A;  4GRH A;  1I7S A;  1I1Q A;  5JY4 A;  2I6Y A;  1I7Q A;  1QDL A;  3RV9 A; 
#chains in the Genus database with same CATH homology
 3OS6 A;  1K0G A;  3R76 A;  3BZM A;  2EUA A;  3R75 A;  5JY4 B;  3RV6 A;  3R74 A;  3ST6 A;  3HWO A;  3VEH A;  5KCK A;  3BZN A;  3LOG A;  5CWA A;  1K0E A;  2G5F A;  5JXZ A;  3GSE A;  2FN1 A;  3RV7 A;  2FN0 A;  3H9M A;  5JZD A;  5JY9 A;  3RV8 A;  5JY8 A;  4GRH A;  1I7S A;  1I1Q A;  5JY4 A;  2I6Y A;  1I7Q A;  1QDL A;  3RV9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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