5JY8A

An iron-bound structure of the isochorismate synthase entc
Total Genus 106
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
375
structure length
368
Chain Sequence
LAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASASLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
pubmed doi rcsb
molecule tags Isomerase
source organism Escherichia coli o157:h7
molecule keywords Isochorismate synthase EntC
total genus 106
structure length 368
sequence length 375
chains with identical sequence B
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2016-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 5jy8A00
3VEHA 1K0GA 3R74A 5CWAA 5JY8A 3HWOA 3RV8A 2FN0A 3RV9A 4GRHA 3GSEA 2G5FA 3RV7A 3ST6A 2FN1A 5JZDA 5JY9A 1I7SA 3R76A 2I6YA 5JY4B 3OS6A 5KCKA 2EUAA 5JY4A 1K0EA 3BZNA 3H9MA 3R75A 5JXZA 1I7QA 3BZMA 1QDLA 1I1QA 3RV6A 3LOGA
chains in the Genus database with same CATH superfamily
3VEHA 1K0GA 3R74A 5CWAA 5JY8A 3HWOA 3RV8A 2FN0A 3RV9A 4GRHA 3GSEA 2G5FA 3RV7A 3ST6A 2FN1A 5JZDA 5JY9A 1I7SA 3R76A 2I6YA 5JY4B 3OS6A 5KCKA 2EUAA 5JY4A 1K0EA 3BZNA 3H9MA 3R75A 5JXZA 1I7QA 3BZMA 1QDLA 1I1QA 3RV6A 3LOGA
chains in the Genus database with same CATH topology
3VEHA 1K0GA 3R74A 5CWAA 5JY8A 3HWOA 3RV8A 2FN0A 3RV9A 4GRHA 3GSEA 2G5FA 3RV7A 3ST6A 2FN1A 5JZDA 5JY9A 1I7SA 3R76A 2I6YA 5JY4B 3OS6A 5KCKA 2EUAA 5JY4A 1K0EA 3BZNA 3H9MA 3R75A 5JXZA 1I7QA 3BZMA 1QDLA 1I1QA 3RV6A 3LOGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VEH A;  1K0G A;  3R74 A;  5CWA A;  5JY8 A;  3HWO A;  3RV8 A;  2FN0 A;  3RV9 A;  4GRH A;  3GSE A;  2G5F A;  3RV7 A;  3ST6 A;  2FN1 A;  5JZD A;  5JY9 A;  1I7S A;  3R76 A;  2I6Y A;  5JY4 B;  3OS6 A;  5KCK A;  2EUA A;  5JY4 A;  1K0E A;  3BZN A;  3H9M A;  3R75 A;  5JXZ A;  1I7Q A;  3BZM A;  1QDL A;  1I1Q A;  3RV6 A;  3LOG A; 
#chains in the Genus database with same CATH topology
 3VEH A;  1K0G A;  3R74 A;  5CWA A;  5JY8 A;  3HWO A;  3RV8 A;  2FN0 A;  3RV9 A;  4GRH A;  3GSE A;  2G5F A;  3RV7 A;  3ST6 A;  2FN1 A;  5JZD A;  5JY9 A;  1I7S A;  3R76 A;  2I6Y A;  5JY4 B;  3OS6 A;  5KCK A;  2EUA A;  5JY4 A;  1K0E A;  3BZN A;  3H9M A;  3R75 A;  5JXZ A;  1I7Q A;  3BZM A;  1QDL A;  1I1Q A;  3RV6 A;  3LOG A; 
#chains in the Genus database with same CATH homology
 3VEH A;  1K0G A;  3R74 A;  5CWA A;  5JY8 A;  3HWO A;  3RV8 A;  2FN0 A;  3RV9 A;  4GRH A;  3GSE A;  2G5F A;  3RV7 A;  3ST6 A;  2FN1 A;  5JZD A;  5JY9 A;  1I7S A;  3R76 A;  2I6Y A;  5JY4 B;  3OS6 A;  5KCK A;  2EUA A;  5JY4 A;  1K0E A;  3BZN A;  3H9M A;  3R75 A;  5JXZ A;  1I7Q A;  3BZM A;  1QDL A;  1I1Q A;  3RV6 A;  3LOG A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...