6JDWA

Crystal structure of human l-arginine:glycine amidinotransferase in complex with gamma-amino butyric acid
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE)
total genus 121
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1998-10-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 6jdwA00
2CI1A 2DEWX 3APMA 3B1UA 1ZBRA 7JDWA 1JDXA 4N2GA 5AK7A 4N2IA 3B1TA 3I2EA 4YT9A 4N2HA 2EWOA 3BPBA 4YTBA 4N28A 2JERA 4DKTA 1LXYA 2ACIA 3P8EA 4N2FA 2DEYX 1WD9A 1WD8A 4N2NA 5AK8A 2ABRA 2CI7A 2JAJA 4N2KA 5M3QA 4N2BA 3P8PA 2CI6A 1BWDA 2CI5A 2DW5A 3APNA 4YTGA 3H7CX 5JDWA 2A9GA 4N2LA 3HVMA 3RHYA 2DEXX 1JDWA 2CI3A 2CI4A 5HP5A 4JDWA 1S9RA 4N2CA 4N2AA 1G62A 4N25A 1G61A 4BOFA 4N2MA 4X8CA 2C6ZA 5AN9I 4N26A 2JAIA 4N2DA 2JDXA 8JDWA 9JDWA 1RXXA 3I4AA 4N2EA 4N24A 2AAFA 3H7KA 2JDWA 1H70A 2Q3UA 1VKPA 6JDWA 4E4JA 3JDWA 2CMUA 4N22A 4N20A 4X8GA 1XKNA 1WDAA
chains in the Genus database with same CATH superfamily
2CI1A 2DEWX 3APMA 3B1UA 1ZBRA 7JDWA 1JDXA 4N2GA 5AK7A 4N2IA 3B1TA 3I2EA 4YT9A 4N2HA 2EWOA 3BPBA 4YTBA 4N28A 2JERA 1YNIA 4DKTA 1LXYA 2ACIA 4N2FA 3P8EA 2DEYX 1WD9A 1WD8A 4N2NA 5AK8A 2ABRA 2CI7A 2JAJA 4N2KA 5M3QA 4N2BA 3P8PA 2CI6A 1BWDA 2CI5A 2DW5A 3APNA 4YTGA 3H7CX 5JDWA 2A9GA 4N2LA 3HVMA 3RHYA 2DEXX 1JDWA 2CI3A 2CI4A 5HP5A 4JDWA 1S9RA 4N2CA 4N2AA 1YNFA 1G62A 4N25A 1G61A 4BOFA 4N2MA 4X8CA 2C6ZA 5AN9I 4N26A 2JAIA 4N2DA 2JDXA 8JDWA 9JDWA 1RXXA 3I4AA 4N2EA 4N24A 2AAFA 1YNHA 3H7KA 2JDWA 1H70A 2Q3UA 1VKPA 6JDWA 4E4JA 3JDWA 2CMUA 4N22A 4N20A 4X8GA 1XKNA 1WDAA
chains in the Genus database with same CATH topology
2CI1A 2DEWX 3APMA 3B1UA 1ZBRA 7JDWA 1JDXA 4N2GA 5AK7A 4N2IA 3B1TA 3I2EA 4YT9A 4N2HA 2EWOA 3BPBA 4YTBA 4N28A 2JERA 4DKTA 1LXYA 2ACIA 3P8EA 4N2FA 2DEYX 1WD9A 1WD8A 4N2NA 5AK8A 2ABRA 2CI7A 2JAJA 4N2KA 5M3QA 4N2BA 3P8PA 2CI6A 1BWDA 2CI5A 2DW5A 3APNA 4YTGA 3H7CX 5JDWA 2A9GA 4N2LA 3HVMA 3RHYA 2DEXX 1JDWA 2CI3A 2CI4A 5HP5A 4JDWA 1S9RA 4N2CA 4N2AA 1G62A 4N25A 1G61A 4BOFA 4N2MA 4X8CA 2C6ZA 5AN9I 4N26A 2JAIA 4N2DA 2JDXA 8JDWA 9JDWA 1RXXA 3I4AA 4N2EA 4N24A 2AAFA 3H7KA 2JDWA 1H70A 2Q3UA 1VKPA 6JDWA 4E4JA 3JDWA 2CMUA 4N22A 4N20A 4X8GA 1XKNA 1WDAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CI1 A;  2DEW X;  3APM A;  3B1U A;  1ZBR A;  7JDW A;  1JDX A;  4N2G A;  5AK7 A;  4N2I A;  3B1T A;  3I2E A;  4YT9 A;  4N2H A;  2EWO A;  3BPB A;  4YTB A;  4N28 A;  2JER A;  4DKT A;  1LXY A;  2ACI A;  3P8E A;  4N2F A;  2DEY X;  1WD9 A;  1WD8 A;  4N2N A;  5AK8 A;  2ABR A;  2CI7 A;  2JAJ A;  4N2K A;  5M3Q A;  4N2B A;  3P8P A;  2CI6 A;  1BWD A;  2CI5 A;  2DW5 A;  3APN A;  4YTG A;  3H7C X;  5JDW A;  2A9G A;  4N2L A;  3HVM A;  3RHY A;  2DEX X;  1JDW A;  2CI3 A;  2CI4 A;  5HP5 A;  4JDW A;  1S9R A;  4N2C A;  4N2A A;  1G62 A;  4N25 A;  1G61 A;  4BOF A;  4N2M A;  4X8C A;  2C6Z A;  5AN9 I;  4N26 A;  2JAI A;  4N2D A;  2JDX A;  8JDW A;  9JDW A;  1RXX A;  3I4A A;  4N2E A;  4N24 A;  2AAF A;  3H7K A;  2JDW A;  1H70 A;  2Q3U A;  1VKP A;  6JDW A;  4E4J A;  3JDW A;  2CMU A;  4N22 A;  4N20 A;  4X8G A;  1XKN A;  1WDA A; 
#chains in the Genus database with same CATH topology
 2CI1 A;  2DEW X;  3APM A;  3B1U A;  1ZBR A;  7JDW A;  1JDX A;  4N2G A;  5AK7 A;  4N2I A;  3B1T A;  3I2E A;  4YT9 A;  4N2H A;  2EWO A;  3BPB A;  4YTB A;  4N28 A;  2JER A;  1YNI A;  4DKT A;  1LXY A;  2ACI A;  4N2F A;  3P8E A;  2DEY X;  1WD9 A;  1WD8 A;  4N2N A;  5AK8 A;  2ABR A;  2CI7 A;  2JAJ A;  4N2K A;  5M3Q A;  4N2B A;  3P8P A;  2CI6 A;  1BWD A;  2CI5 A;  2DW5 A;  3APN A;  4YTG A;  3H7C X;  5JDW A;  2A9G A;  4N2L A;  3HVM A;  3RHY A;  2DEX X;  1JDW A;  2CI3 A;  2CI4 A;  5HP5 A;  4JDW A;  1S9R A;  4N2C A;  4N2A A;  1YNF A;  1G62 A;  4N25 A;  1G61 A;  4BOF A;  4N2M A;  4X8C A;  2C6Z A;  5AN9 I;  4N26 A;  2JAI A;  4N2D A;  2JDX A;  8JDW A;  9JDW A;  1RXX A;  3I4A A;  4N2E A;  4N24 A;  2AAF A;  1YNH A;  3H7K A;  2JDW A;  1H70 A;  2Q3U A;  1VKP A;  6JDW A;  4E4J A;  3JDW A;  2CMU A;  4N22 A;  4N20 A;  4X8G A;  1XKN A;  1WDA A; 
#chains in the Genus database with same CATH homology
 2CI1 A;  2DEW X;  3APM A;  3B1U A;  1ZBR A;  7JDW A;  1JDX A;  4N2G A;  5AK7 A;  4N2I A;  3B1T A;  3I2E A;  4YT9 A;  4N2H A;  2EWO A;  3BPB A;  4YTB A;  4N28 A;  2JER A;  4DKT A;  1LXY A;  2ACI A;  3P8E A;  4N2F A;  2DEY X;  1WD9 A;  1WD8 A;  4N2N A;  5AK8 A;  2ABR A;  2CI7 A;  2JAJ A;  4N2K A;  5M3Q A;  4N2B A;  3P8P A;  2CI6 A;  1BWD A;  2CI5 A;  2DW5 A;  3APN A;  4YTG A;  3H7C X;  5JDW A;  2A9G A;  4N2L A;  3HVM A;  3RHY A;  2DEX X;  1JDW A;  2CI3 A;  2CI4 A;  5HP5 A;  4JDW A;  1S9R A;  4N2C A;  4N2A A;  1G62 A;  4N25 A;  1G61 A;  4BOF A;  4N2M A;  4X8C A;  2C6Z A;  5AN9 I;  4N26 A;  2JAI A;  4N2D A;  2JDX A;  8JDW A;  9JDW A;  1RXX A;  3I4A A;  4N2E A;  4N24 A;  2AAF A;  3H7K A;  2JDW A;  1H70 A;  2Q3U A;  1VKP A;  6JDW A;  4E4J A;  3JDW A;  2CMU A;  4N22 A;  4N20 A;  4X8G A;  1XKN A;  1WDA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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