7JDWA

Crystal structure of human l-arginine:glycine amidinotransferase in complex with delta-amino valeric acid
Total Genus 122
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE)
total genus 122
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1998-10-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 7jdwA00
4N2MA 3H7KA 3APNA 2CI6A 1S9RA 3B1UA 1XKNA 2CI3A 2DEYX 1VKPA 2Q3UA 1H70A 2ACIA 3I4AA 2EWOA 4N2FA 4BOFA 2DEWX 1BWDA 3APMA 2JAJA 6JDWA 4N2BA 3B1TA 2C6ZA 3P8EA 5AK7A 2CMUA 1JDXA 4JDWA 4N2LA 4N24A 4YTBA 1G62A 1ZBRA 2JDWA 4N25A 4X8GA 4DKTA 3BPBA 1WD9A 3H7CX 1G61A 3HVMA 3P8PA 1JDWA 7JDWA 2ABRA 2JDXA 4N22A 4N2CA 4N2DA 4E4JA 4N26A 8JDWA 4N2KA 5AK8A 2A9GA 2CI1A 2CI4A 4N20A 2DW5A 4N2EA 5AN9I 3RHYA 2JAIA 4YTGA 2CI7A 1WD8A 4YT9A 9JDWA 2AAFA 3JDWA 1LXYA 4N2HA 5JDWA 5HP5A 3I2EA 2JERA 4N28A 1RXXA 2DEXX 4N2NA 1WDAA 2CI5A 4N2GA 4X8CA 4N2IA 5M3QA 4N2AA
chains in the Genus database with same CATH superfamily
4N2MA 3H7KA 3APNA 2CI6A 1S9RA 3B1UA 1XKNA 1YNFA 2CI3A 2DEYX 1VKPA 2Q3UA 1H70A 2ACIA 3I4AA 2EWOA 4N2FA 4BOFA 2DEWX 1BWDA 3APMA 2JAJA 6JDWA 4N2BA 3B1TA 2C6ZA 3P8EA 5AK7A 2CMUA 1JDXA 1YNHA 4JDWA 4N2LA 4N24A 4YTBA 1G62A 1ZBRA 2JDWA 4N25A 4X8GA 4DKTA 3BPBA 1WD9A 3H7CX 1G61A 3HVMA 3P8PA 1JDWA 7JDWA 2ABRA 2JDXA 4N22A 4N2CA 4N2DA 4E4JA 4N26A 8JDWA 4N2KA 5AK8A 2A9GA 2CI1A 2CI4A 4N20A 2DW5A 4N2EA 5AN9I 3RHYA 2JAIA 4YTGA 2CI7A 1WD8A 4YT9A 9JDWA 2AAFA 3JDWA 1LXYA 4N2HA 5JDWA 5HP5A 3I2EA 2JERA 4N28A 1RXXA 2DEXX 1YNIA 4N2NA 1WDAA 2CI5A 4N2GA 4X8CA 4N2IA 5M3QA 4N2AA
chains in the Genus database with same CATH topology
4N2MA 3H7KA 3APNA 2CI6A 1S9RA 3B1UA 1XKNA 2CI3A 2DEYX 1VKPA 2Q3UA 1H70A 2ACIA 3I4AA 2EWOA 4N2FA 4BOFA 2DEWX 1BWDA 3APMA 2JAJA 6JDWA 4N2BA 3B1TA 2C6ZA 3P8EA 5AK7A 2CMUA 1JDXA 4JDWA 4N2LA 4N24A 4YTBA 1G62A 1ZBRA 2JDWA 4N25A 4X8GA 4DKTA 3BPBA 1WD9A 3H7CX 1G61A 3HVMA 3P8PA 1JDWA 7JDWA 2ABRA 2JDXA 4N22A 4N2CA 4N2DA 4E4JA 4N26A 8JDWA 4N2KA 5AK8A 2A9GA 2CI1A 2CI4A 4N20A 2DW5A 4N2EA 5AN9I 3RHYA 2JAIA 4YTGA 2CI7A 1WD8A 4YT9A 9JDWA 2AAFA 3JDWA 1LXYA 4N2HA 5JDWA 5HP5A 3I2EA 2JERA 4N28A 1RXXA 2DEXX 4N2NA 1WDAA 2CI5A 4N2GA 4X8CA 4N2IA 5M3QA 4N2AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N2M A;  3H7K A;  3APN A;  2CI6 A;  1S9R A;  3B1U A;  1XKN A;  2CI3 A;  2DEY X;  1VKP A;  2Q3U A;  1H70 A;  2ACI A;  3I4A A;  2EWO A;  4N2F A;  4BOF A;  2DEW X;  1BWD A;  3APM A;  2JAJ A;  6JDW A;  4N2B A;  3B1T A;  2C6Z A;  3P8E A;  5AK7 A;  2CMU A;  1JDX A;  4JDW A;  4N2L A;  4N24 A;  4YTB A;  1G62 A;  1ZBR A;  2JDW A;  4N25 A;  4X8G A;  4DKT A;  3BPB A;  1WD9 A;  3H7C X;  1G61 A;  3HVM A;  3P8P A;  1JDW A;  7JDW A;  2ABR A;  2JDX A;  4N22 A;  4N2C A;  4N2D A;  4E4J A;  4N26 A;  8JDW A;  4N2K A;  5AK8 A;  2A9G A;  2CI1 A;  2CI4 A;  4N20 A;  2DW5 A;  4N2E A;  5AN9 I;  3RHY A;  2JAI A;  4YTG A;  2CI7 A;  1WD8 A;  4YT9 A;  9JDW A;  2AAF A;  3JDW A;  1LXY A;  4N2H A;  5JDW A;  5HP5 A;  3I2E A;  2JER A;  4N28 A;  1RXX A;  2DEX X;  4N2N A;  1WDA A;  2CI5 A;  4N2G A;  4X8C A;  4N2I A;  5M3Q A;  4N2A A; 
#chains in the Genus database with same CATH topology
 4N2M A;  3H7K A;  3APN A;  2CI6 A;  1S9R A;  3B1U A;  1XKN A;  1YNF A;  2CI3 A;  2DEY X;  1VKP A;  2Q3U A;  1H70 A;  2ACI A;  3I4A A;  2EWO A;  4N2F A;  4BOF A;  2DEW X;  1BWD A;  3APM A;  2JAJ A;  6JDW A;  4N2B A;  3B1T A;  2C6Z A;  3P8E A;  5AK7 A;  2CMU A;  1JDX A;  1YNH A;  4JDW A;  4N2L A;  4N24 A;  4YTB A;  1G62 A;  1ZBR A;  2JDW A;  4N25 A;  4X8G A;  4DKT A;  3BPB A;  1WD9 A;  3H7C X;  1G61 A;  3HVM A;  3P8P A;  1JDW A;  7JDW A;  2ABR A;  2JDX A;  4N22 A;  4N2C A;  4N2D A;  4E4J A;  4N26 A;  8JDW A;  4N2K A;  5AK8 A;  2A9G A;  2CI1 A;  2CI4 A;  4N20 A;  2DW5 A;  4N2E A;  5AN9 I;  3RHY A;  2JAI A;  4YTG A;  2CI7 A;  1WD8 A;  4YT9 A;  9JDW A;  2AAF A;  3JDW A;  1LXY A;  4N2H A;  5JDW A;  5HP5 A;  3I2E A;  2JER A;  4N28 A;  1RXX A;  2DEX X;  1YNI A;  4N2N A;  1WDA A;  2CI5 A;  4N2G A;  4X8C A;  4N2I A;  5M3Q A;  4N2A A; 
#chains in the Genus database with same CATH homology
 4N2M A;  3H7K A;  3APN A;  2CI6 A;  1S9R A;  3B1U A;  1XKN A;  2CI3 A;  2DEY X;  1VKP A;  2Q3U A;  1H70 A;  2ACI A;  3I4A A;  2EWO A;  4N2F A;  4BOF A;  2DEW X;  1BWD A;  3APM A;  2JAJ A;  6JDW A;  4N2B A;  3B1T A;  2C6Z A;  3P8E A;  5AK7 A;  2CMU A;  1JDX A;  4JDW A;  4N2L A;  4N24 A;  4YTB A;  1G62 A;  1ZBR A;  2JDW A;  4N25 A;  4X8G A;  4DKT A;  3BPB A;  1WD9 A;  3H7C X;  1G61 A;  3HVM A;  3P8P A;  1JDW A;  7JDW A;  2ABR A;  2JDX A;  4N22 A;  4N2C A;  4N2D A;  4E4J A;  4N26 A;  8JDW A;  4N2K A;  5AK8 A;  2A9G A;  2CI1 A;  2CI4 A;  4N20 A;  2DW5 A;  4N2E A;  5AN9 I;  3RHY A;  2JAI A;  4YTG A;  2CI7 A;  1WD8 A;  4YT9 A;  9JDW A;  2AAF A;  3JDW A;  1LXY A;  4N2H A;  5JDW A;  5HP5 A;  3I2E A;  2JER A;  4N28 A;  1RXX A;  2DEX X;  4N2N A;  1WDA A;  2CI5 A;  4N2G A;  4X8C A;  4N2I A;  5M3Q A;  4N2A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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