8JDWA

Crystal structure of human l-arginine:glycine amidinotransferase in complex with l-alanine
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE)
total genus 125
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1998-10-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 8jdwA00
2A9GA 1RXXA 3HVMA 3I4AA 3P8EA 2AAFA 4X8GA 2DEXX 2CI3A 2DW5A 4N20A 5AK8A 8JDWA 4X8CA 2JDWA 2ACIA 2CMUA 1WD8A 1BWDA 2C6ZA 3RHYA 2DEYX 2JAIA 4N24A 2CI7A 4N2KA 4N2EA 3I2EA 5HP5A 4N2CA 5AN9I 2Q3UA 2CI5A 4N22A 4N2FA 4YT9A 4N2HA 4N2BA 4N2DA 5AK7A 2CI4A 3H7CX 5M3QA 7JDWA 4N26A 1VKPA 1ZBRA 2CI6A 2ABRA 1G61A 9JDWA 3P8PA 1WDAA 2EWOA 4YTGA 4N2GA 2DEWX 4YTBA 6JDWA 3APNA 4N2AA 1S9RA 2JDXA 2JAJA 3JDWA 4N28A 3BPBA 4N25A 4N2NA 4E4JA 1G62A 4BOFA 1JDXA 3B1TA 2CI1A 3APMA 1H70A 4N2LA 1LXYA 3H7KA 5JDWA 4N2IA 1WD9A 3B1UA 4DKTA 1JDWA 4N2MA 4JDWA 2JERA 1XKNA
chains in the Genus database with same CATH superfamily
2A9GA 1RXXA 3HVMA 3I4AA 3P8EA 2AAFA 4X8GA 2DEXX 2CI3A 2DW5A 4N20A 1YNHA 5AK8A 8JDWA 4X8CA 2JDWA 2ACIA 2CMUA 1WD8A 1BWDA 2C6ZA 3RHYA 2DEYX 2JAIA 4N24A 2CI7A 4N2KA 4N2EA 3I2EA 5HP5A 4N2CA 5AN9I 2Q3UA 2CI5A 4N22A 4N2FA 4YT9A 4N2HA 4N2BA 4N2DA 5AK7A 2CI4A 3H7CX 5M3QA 7JDWA 4N26A 1VKPA 1ZBRA 2CI6A 2ABRA 1G61A 9JDWA 3P8PA 1WDAA 2EWOA 4YTGA 4N2GA 2DEWX 4YTBA 6JDWA 1YNIA 3APNA 4N2AA 1S9RA 2JDXA 2JAJA 3JDWA 1YNFA 4N28A 3BPBA 4N25A 4N2NA 4E4JA 1G62A 4BOFA 1JDXA 3B1TA 2CI1A 3APMA 1H70A 4N2LA 1LXYA 3H7KA 5JDWA 4N2IA 1WD9A 3B1UA 4DKTA 1JDWA 4N2MA 4JDWA 2JERA 1XKNA
chains in the Genus database with same CATH topology
2A9GA 1RXXA 3HVMA 3I4AA 3P8EA 2AAFA 4X8GA 2DEXX 2CI3A 2DW5A 4N20A 5AK8A 8JDWA 4X8CA 2JDWA 2ACIA 2CMUA 1WD8A 1BWDA 2C6ZA 3RHYA 2DEYX 2JAIA 4N24A 2CI7A 4N2KA 4N2EA 3I2EA 5HP5A 4N2CA 5AN9I 2Q3UA 2CI5A 4N22A 4N2FA 4YT9A 4N2HA 4N2BA 4N2DA 5AK7A 2CI4A 3H7CX 5M3QA 7JDWA 4N26A 1VKPA 1ZBRA 2CI6A 2ABRA 1G61A 9JDWA 3P8PA 1WDAA 2EWOA 4YTGA 4N2GA 2DEWX 4YTBA 6JDWA 3APNA 4N2AA 1S9RA 2JDXA 2JAJA 3JDWA 4N28A 3BPBA 4N25A 4N2NA 4E4JA 1G62A 4BOFA 1JDXA 3B1TA 2CI1A 3APMA 1H70A 4N2LA 1LXYA 3H7KA 5JDWA 4N2IA 1WD9A 3B1UA 4DKTA 1JDWA 4N2MA 4JDWA 2JERA 1XKNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A9G A;  1RXX A;  3HVM A;  3I4A A;  3P8E A;  2AAF A;  4X8G A;  2DEX X;  2CI3 A;  2DW5 A;  4N20 A;  5AK8 A;  8JDW A;  4X8C A;  2JDW A;  2ACI A;  2CMU A;  1WD8 A;  1BWD A;  2C6Z A;  3RHY A;  2DEY X;  2JAI A;  4N24 A;  2CI7 A;  4N2K A;  4N2E A;  3I2E A;  5HP5 A;  4N2C A;  5AN9 I;  2Q3U A;  2CI5 A;  4N22 A;  4N2F A;  4YT9 A;  4N2H A;  4N2B A;  4N2D A;  5AK7 A;  2CI4 A;  3H7C X;  5M3Q A;  7JDW A;  4N26 A;  1VKP A;  1ZBR A;  2CI6 A;  2ABR A;  1G61 A;  9JDW A;  3P8P A;  1WDA A;  2EWO A;  4YTG A;  4N2G A;  2DEW X;  4YTB A;  6JDW A;  3APN A;  4N2A A;  1S9R A;  2JDX A;  2JAJ A;  3JDW A;  4N28 A;  3BPB A;  4N25 A;  4N2N A;  4E4J A;  1G62 A;  4BOF A;  1JDX A;  3B1T A;  2CI1 A;  3APM A;  1H70 A;  4N2L A;  1LXY A;  3H7K A;  5JDW A;  4N2I A;  1WD9 A;  3B1U A;  4DKT A;  1JDW A;  4N2M A;  4JDW A;  2JER A;  1XKN A; 
#chains in the Genus database with same CATH topology
 2A9G A;  1RXX A;  3HVM A;  3I4A A;  3P8E A;  2AAF A;  4X8G A;  2DEX X;  2CI3 A;  2DW5 A;  4N20 A;  1YNH A;  5AK8 A;  8JDW A;  4X8C A;  2JDW A;  2ACI A;  2CMU A;  1WD8 A;  1BWD A;  2C6Z A;  3RHY A;  2DEY X;  2JAI A;  4N24 A;  2CI7 A;  4N2K A;  4N2E A;  3I2E A;  5HP5 A;  4N2C A;  5AN9 I;  2Q3U A;  2CI5 A;  4N22 A;  4N2F A;  4YT9 A;  4N2H A;  4N2B A;  4N2D A;  5AK7 A;  2CI4 A;  3H7C X;  5M3Q A;  7JDW A;  4N26 A;  1VKP A;  1ZBR A;  2CI6 A;  2ABR A;  1G61 A;  9JDW A;  3P8P A;  1WDA A;  2EWO A;  4YTG A;  4N2G A;  2DEW X;  4YTB A;  6JDW A;  1YNI A;  3APN A;  4N2A A;  1S9R A;  2JDX A;  2JAJ A;  3JDW A;  1YNF A;  4N28 A;  3BPB A;  4N25 A;  4N2N A;  4E4J A;  1G62 A;  4BOF A;  1JDX A;  3B1T A;  2CI1 A;  3APM A;  1H70 A;  4N2L A;  1LXY A;  3H7K A;  5JDW A;  4N2I A;  1WD9 A;  3B1U A;  4DKT A;  1JDW A;  4N2M A;  4JDW A;  2JER A;  1XKN A; 
#chains in the Genus database with same CATH homology
 2A9G A;  1RXX A;  3HVM A;  3I4A A;  3P8E A;  2AAF A;  4X8G A;  2DEX X;  2CI3 A;  2DW5 A;  4N20 A;  5AK8 A;  8JDW A;  4X8C A;  2JDW A;  2ACI A;  2CMU A;  1WD8 A;  1BWD A;  2C6Z A;  3RHY A;  2DEY X;  2JAI A;  4N24 A;  2CI7 A;  4N2K A;  4N2E A;  3I2E A;  5HP5 A;  4N2C A;  5AN9 I;  2Q3U A;  2CI5 A;  4N22 A;  4N2F A;  4YT9 A;  4N2H A;  4N2B A;  4N2D A;  5AK7 A;  2CI4 A;  3H7C X;  5M3Q A;  7JDW A;  4N26 A;  1VKP A;  1ZBR A;  2CI6 A;  2ABR A;  1G61 A;  9JDW A;  3P8P A;  1WDA A;  2EWO A;  4YTG A;  4N2G A;  2DEW X;  4YTB A;  6JDW A;  3APN A;  4N2A A;  1S9R A;  2JDX A;  2JAJ A;  3JDW A;  4N28 A;  3BPB A;  4N25 A;  4N2N A;  4E4J A;  1G62 A;  4BOF A;  1JDX A;  3B1T A;  2CI1 A;  3APM A;  1H70 A;  4N2L A;  1LXY A;  3H7K A;  5JDW A;  4N2I A;  1WD9 A;  3B1U A;  4DKT A;  1JDW A;  4N2M A;  4JDW A;  2JER A;  1XKN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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