8JDWA

Crystal structure of human l-arginine:glycine amidinotransferase in complex with l-alanine
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
360
structure length
360
Chain Sequence
CPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE)
total genus 125
structure length 360
sequence length 360
ec nomenclature ec 2.1.4.1: Glycine amidinotransferase.
pdb deposition date 1998-10-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.75.10.10 Alpha Beta 5-stranded Propeller L-arginine/glycine Amidinotransferase; Chain A L-arginine/glycine Amidinotransferase; Chain A 8jdwA00
3P8EA 4N2GA 2EWOA 4N2LA 3JDWA 5JDWA 5AK7A 1G62A 3H7CX 2DEYX 9JDWA 3RHYA 3APNA 4N2AA 1ZBRA 4N22A 1XKNA 2JAJA 4BOFA 7JDWA 2CI6A 6JDWA 2CI7A 4N2IA 4N2MA 1H70A 4N2CA 1VKPA 2JDXA 4N2DA 4N26A 2DW5A 3H7KA 2Q3UA 5M3QA 1S9RA 2ACIA 2DEXX 4X8CA 2JDWA 2JERA 1JDWA 4N2EA 3I2EA 4YTBA 1BWDA 2CMUA 1JDXA 1WD8A 8JDWA 2CI3A 4DKTA 2DEWX 3BPBA 5AK8A 3HVMA 2ABRA 4E4JA 4N2HA 4N24A 1RXXA 4N2KA 1WDAA 4N2NA 3B1UA 2C6ZA 4YT9A 2CI4A 4N2FA 4N25A 3P8PA 2CI5A 4JDWA 4YTGA 2AAFA 4X8GA 3I4AA 5AN9I 3APMA 4N28A 1WD9A 3B1TA 2A9GA 2JAIA 5HP5A 1LXYA 2CI1A 4N20A 4N2BA 1G61A
chains in the Genus database with same CATH superfamily
3P8EA 4N2GA 2EWOA 4N2LA 3JDWA 5JDWA 5AK7A 1G62A 3H7CX 2DEYX 9JDWA 3RHYA 3APNA 4N2AA 1ZBRA 4N22A 1XKNA 2JAJA 4BOFA 7JDWA 2CI6A 6JDWA 2CI7A 4N2IA 4N2MA 1H70A 4N2CA 1VKPA 2JDXA 4N2DA 4N26A 2DW5A 3H7KA 2Q3UA 5M3QA 1S9RA 2ACIA 2DEXX 4X8CA 2JDWA 2JERA 1JDWA 4N2EA 1YNHA 3I2EA 4YTBA 1BWDA 2CMUA 1JDXA 1WD8A 8JDWA 2CI3A 4DKTA 2DEWX 3BPBA 5AK8A 3HVMA 2ABRA 4E4JA 4N2HA 4N24A 1RXXA 4N2KA 1WDAA 4N2NA 3B1UA 2C6ZA 4YT9A 2CI4A 4N2FA 4N25A 1YNFA 3P8PA 2CI5A 4JDWA 4YTGA 2AAFA 4X8GA 3I4AA 5AN9I 1YNIA 3APMA 4N28A 1WD9A 3B1TA 2A9GA 2JAIA 5HP5A 1LXYA 2CI1A 4N20A 4N2BA 1G61A
chains in the Genus database with same CATH topology
3P8EA 4N2GA 2EWOA 4N2LA 3JDWA 5JDWA 5AK7A 1G62A 3H7CX 2DEYX 9JDWA 3RHYA 3APNA 4N2AA 1ZBRA 4N22A 1XKNA 2JAJA 4BOFA 7JDWA 2CI6A 6JDWA 2CI7A 4N2IA 4N2MA 1H70A 4N2CA 1VKPA 2JDXA 4N2DA 4N26A 2DW5A 3H7KA 2Q3UA 5M3QA 1S9RA 2ACIA 2DEXX 4X8CA 2JDWA 2JERA 1JDWA 4N2EA 3I2EA 4YTBA 1BWDA 2CMUA 1JDXA 1WD8A 8JDWA 2CI3A 4DKTA 2DEWX 3BPBA 5AK8A 3HVMA 2ABRA 4E4JA 4N2HA 4N24A 1RXXA 4N2KA 1WDAA 4N2NA 3B1UA 2C6ZA 4YT9A 2CI4A 4N2FA 4N25A 3P8PA 2CI5A 4JDWA 4YTGA 2AAFA 4X8GA 3I4AA 5AN9I 3APMA 4N28A 1WD9A 3B1TA 2A9GA 2JAIA 5HP5A 1LXYA 2CI1A 4N20A 4N2BA 1G61A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P8E A;  4N2G A;  2EWO A;  4N2L A;  3JDW A;  5JDW A;  5AK7 A;  1G62 A;  3H7C X;  2DEY X;  9JDW A;  3RHY A;  3APN A;  4N2A A;  1ZBR A;  4N22 A;  1XKN A;  2JAJ A;  4BOF A;  7JDW A;  2CI6 A;  6JDW A;  2CI7 A;  4N2I A;  4N2M A;  1H70 A;  4N2C A;  1VKP A;  2JDX A;  4N2D A;  4N26 A;  2DW5 A;  3H7K A;  2Q3U A;  5M3Q A;  1S9R A;  2ACI A;  2DEX X;  4X8C A;  2JDW A;  2JER A;  1JDW A;  4N2E A;  3I2E A;  4YTB A;  1BWD A;  2CMU A;  1JDX A;  1WD8 A;  8JDW A;  2CI3 A;  4DKT A;  2DEW X;  3BPB A;  5AK8 A;  3HVM A;  2ABR A;  4E4J A;  4N2H A;  4N24 A;  1RXX A;  4N2K A;  1WDA A;  4N2N A;  3B1U A;  2C6Z A;  4YT9 A;  2CI4 A;  4N2F A;  4N25 A;  3P8P A;  2CI5 A;  4JDW A;  4YTG A;  2AAF A;  4X8G A;  3I4A A;  5AN9 I;  3APM A;  4N28 A;  1WD9 A;  3B1T A;  2A9G A;  2JAI A;  5HP5 A;  1LXY A;  2CI1 A;  4N20 A;  4N2B A;  1G61 A; 
#chains in the Genus database with same CATH topology
 3P8E A;  4N2G A;  2EWO A;  4N2L A;  3JDW A;  5JDW A;  5AK7 A;  1G62 A;  3H7C X;  2DEY X;  9JDW A;  3RHY A;  3APN A;  4N2A A;  1ZBR A;  4N22 A;  1XKN A;  2JAJ A;  4BOF A;  7JDW A;  2CI6 A;  6JDW A;  2CI7 A;  4N2I A;  4N2M A;  1H70 A;  4N2C A;  1VKP A;  2JDX A;  4N2D A;  4N26 A;  2DW5 A;  3H7K A;  2Q3U A;  5M3Q A;  1S9R A;  2ACI A;  2DEX X;  4X8C A;  2JDW A;  2JER A;  1JDW A;  4N2E A;  1YNH A;  3I2E A;  4YTB A;  1BWD A;  2CMU A;  1JDX A;  1WD8 A;  8JDW A;  2CI3 A;  4DKT A;  2DEW X;  3BPB A;  5AK8 A;  3HVM A;  2ABR A;  4E4J A;  4N2H A;  4N24 A;  1RXX A;  4N2K A;  1WDA A;  4N2N A;  3B1U A;  2C6Z A;  4YT9 A;  2CI4 A;  4N2F A;  4N25 A;  1YNF A;  3P8P A;  2CI5 A;  4JDW A;  4YTG A;  2AAF A;  4X8G A;  3I4A A;  5AN9 I;  1YNI A;  3APM A;  4N28 A;  1WD9 A;  3B1T A;  2A9G A;  2JAI A;  5HP5 A;  1LXY A;  2CI1 A;  4N20 A;  4N2B A;  1G61 A; 
#chains in the Genus database with same CATH homology
 3P8E A;  4N2G A;  2EWO A;  4N2L A;  3JDW A;  5JDW A;  5AK7 A;  1G62 A;  3H7C X;  2DEY X;  9JDW A;  3RHY A;  3APN A;  4N2A A;  1ZBR A;  4N22 A;  1XKN A;  2JAJ A;  4BOF A;  7JDW A;  2CI6 A;  6JDW A;  2CI7 A;  4N2I A;  4N2M A;  1H70 A;  4N2C A;  1VKP A;  2JDX A;  4N2D A;  4N26 A;  2DW5 A;  3H7K A;  2Q3U A;  5M3Q A;  1S9R A;  2ACI A;  2DEX X;  4X8C A;  2JDW A;  2JER A;  1JDW A;  4N2E A;  3I2E A;  4YTB A;  1BWD A;  2CMU A;  1JDX A;  1WD8 A;  8JDW A;  2CI3 A;  4DKT A;  2DEW X;  3BPB A;  5AK8 A;  3HVM A;  2ABR A;  4E4J A;  4N2H A;  4N24 A;  1RXX A;  4N2K A;  1WDA A;  4N2N A;  3B1U A;  2C6Z A;  4YT9 A;  2CI4 A;  4N2F A;  4N25 A;  3P8P A;  2CI5 A;  4JDW A;  4YTG A;  2AAF A;  4X8G A;  3I4A A;  5AN9 I;  3APM A;  4N28 A;  1WD9 A;  3B1T A;  2A9G A;  2JAI A;  5HP5 A;  1LXY A;  2CI1 A;  4N20 A;  4N2B A;  1G61 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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