2EGWA

Crystal structure of rrna methyltransferase with sah ligand
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rRNA methyltransferase with SAH ligand
rcsb
molecule tags Rna methyltransferase
source organism Aquifex aeolicus
molecule keywords UPF0088 protein aq_165
total genus 71
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egwA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egwA02
4YQLA 4XBOA 1X7OA 3O7BA 1VHYA 4E8BA 3KTYA 4JALA 4YQ5A 4JAKA 2CX8A 4MCDA 3AI9X 2YY8A 3DCMX 1VH0A 2HA8A 3ONPA 1O6DA 3IC6A 5FAIA 4H3ZA 3OIJA 4YQ0A 4YQTA 1TO0A 4YQQA 4YQCA 4YVIA 1GZ0A 4YPYA 5D9FA 4YQ1A 3ILKA 4YQ9A 3KNUA 2I6DA 2Z0YA 4YQJA 3KY7A 3OIIA 4J3CA 4IG6A 3N4KA 1IPAA 4PZKA 4CNGA 4YQ7A 2EGVA 1ZJRA 3NK7A 1J85A 1NS5A 3AXZA 2QWVA 4YVJA 4KDZA 1X7PA 4CNEA 3IEFA 4L69A 4YQGA 4X3MA 4YPZA 2V3KA 1Z85A 1UAKA 3NK6A 3OINA 2EGWA 4X3LA 4YPWA 1K3RA 3AIAA 4YQOA 4YQBA 4YVGA 5GMCA 4YQRA 4YQAA 4YVHA 4YQSA 5GMBA 3GYQA 1P9PA 4MCBA 4YVKA 4CNFA 1V2XA 4RG1A 1V6ZA 2O3AA 4MCCA 2V3JA 4YQ6A 1UAJA 1UAMA 4YQKA 1MXIA 4H3YA 1UALA 3N4JA 4KGNA 4YPXA 4YQIA 4YQPA 4YQ8A 2QMMA 3BBEA 4CNDA 4YQ2A 3QUVA 3E5YA 5GM8A 1VHKA 4YQNA 3KW2A 4YQDA 4YQ3A 5CO4A 4FAKA 3BBHA 3L8UA 1OY5A 2NWAA 4YQ4A 1NXZA 3BBDA
chains in the Genus database with same CATH superfamily
4YQLA 1EUYA 4JWJA 4XBOA 1X7OA 3O7BA 1VHYA 2RE8A 4E8BA 3KTYA 4FMWA 4JALA 4YQ5A 4JAKA 2CX8A 4MCDA 4H3SA 3AI9X 2YY8A 3DCMX 1VH0A 2HA8A 3ONPA 1QRSA 1O6DA 3PIOS 3IC6A 5FAIA 4JWGA 4H3ZA 3OIJA 2PNWA 4YQ0A 4WFNS 4YQTA 4YQQA 4YQCA 4P2BA 4YVIA 3CZBA 1GZ0A 4YPYA 5D9FA 4YQ1A 3ILKA 2PI8A 4YQ9A 2I6DA 2Z0YA 3KNUA 4YQJA 2ZJPS 1EXDA 3KY7A 3W2VB 1DFUP 4IO9S 3OIIA 5BNZA 4J3CA 4WFAS 5IZNA 5DM6S 4IG6A 3N4KA 4H4KA 3CF5S 5JVGS 1IPAA 4PZKA 2ZJQS 4IOCS 4CNGA 1O0BA 4YQ7A 2RD2A 4WFBS 2EGVA 1ZJRA 3NK7A 1J85A 1NS5A 1QRTA 3AXZA 2QWVA 3DLLS 4UY88 4YVJA 4KDZA 1X7PA 4CNEA 3IEFA 4L69A 4YQGA 5JVHS 4X3MA 4YPZA 2V3KA 1Z85A 1UAKA 3NK6A 5HL7S 3OINA 2G6GA 4WCES 2EGWA 3J7ZV 4X3LA 5GAGW 4YPWA 1K3RA 3AIAA 1QRUA 4IOAS 4YQOA 2PICA 4YQBA 4YVGA 1O0CA 5GMCA 4YQRA 1NYLA 3W2WB 1B75A 4YQAA 4YVHA 4YQSA 5GMBA 3GYQA 4JXZA 1P9PA 2PJJA 4MCBA 4CNFA 4YVKA 4V194 1V2XA 4RG1A 1V6ZA 1D6KA 2O3AA 4JYZA 1FEUA 4MCCA 4JXXA 2V3JA 4U67S 4YQ6A 1QTQA 4WF9S 1UAJA 1UAMA 2ZJRS 4YQKA 1MXIA 4H3YA 1UDXA 5GAEW 1UALA 1GTRA 3N4JA 4KGNA 2HZ7A 5DM7S 4YPXA 4YQIA 4YQPA 3PIPS 4YQ8A 2QMMA 2G5DA 3BBEA 4CNDA 4YQ2A 1GTSA 4JWFA 3QUVA 3X1LB 3E5YA 5GM8A 2GAEA 1VHKA 5GADW 1ZJWA 5GAHW 4YQNA 3AIIA 3KW2A 1EUQA 4YQDA 2AE0X 4YQ3A 5CO4A 4FAKA 3BBHA 3L8UA 1OY5A 2NWAA 3BBDA 4JWHA 4YQ4A 1NXZA 1TO0A
chains in the Genus database with same CATH topology
4YQLA 4JWJA 4XBOA 1X7OA 3O7BA 1VHYA 4E8BA 3KTYA 4FMWA 4JALA 4YQ5A 4JAKA 2CX8A 4MCDA 3AI9X 2YY8A 3DCMX 1VH0A 2HA8A 3ONPA 1O6DA 3IC6A 5FAIA 4JWGA 4H3ZA 3OIJA 4YQ0A 4YQTA 1TO0A 4YQQA 4YQCA 4YVIA 1GZ0A 4YPYA 5D9FA 4YQ1A 3ILKA 4YQ9A 3KNUA 2I6DA 2Z0YA 4YQJA 3KY7A 3OIIA 4J3CA 4IG6A 3N4KA 1IPAA 4PZKA 4CNGA 4YQ7A 2EGVA 1ZJRA 3NK7A 1J85A 1NS5A 3AXZA 2QWVA 4YVJA 4KDZA 1X7PA 4CNEA 3IEFA 4L69A 4YQGA 4X3MA 4YPZA 2V3KA 1Z85A 1UAKA 3NK6A 3OINA 2EGWA 4X3LA 4YPWA 1K3RA 3AIAA 4YQOA 4YQBA 4YVGA 5GMCA 4YQRA 4YQAA 4YVHA 4YQSA 5GMBA 3GYQA 1P9PA 4MCBA 4YVKA 4CNFA 1V2XA 4RG1A 1V6ZA 2O3AA 4MCCA 2V3JA 4YQ6A 1UAJA 1UAMA 4YQKA 1MXIA 4H3YA 1UALA 3N4JA 4KGNA 4YPXA 4YQIA 4YQPA 4YQ8A 2QMMA 3BBEA 4CNDA 4YQ2A 4JWFA 3QUVA 3E5YA 5GM8A 1VHKA 4YQNA 3KW2A 4YQDA 4YQ3A 5CO4A 4FAKA 3BBHA 3L8UA 1OY5A 2NWAA 4JWHA 4YQ4A 1NXZA 3BBDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQL A;  4XBO A;  1X7O A;  3O7B A;  1VHY A;  4E8B A;  3KTY A;  4JAL A;  4YQ5 A;  4JAK A;  2CX8 A;  4MCD A;  3AI9 X;  2YY8 A;  3DCM X;  1VH0 A;  2HA8 A;  3ONP A;  1O6D A;  3IC6 A;  5FAI A;  4H3Z A;  3OIJ A;  4YQ0 A;  4YQT A;  1TO0 A;  4YQQ A;  4YQC A;  4YVI A;  1GZ0 A;  4YPY A;  5D9F A;  4YQ1 A;  3ILK A;  4YQ9 A;  3KNU A;  2I6D A;  2Z0Y A;  4YQJ A;  3KY7 A;  3OII A;  4J3C A;  4IG6 A;  3N4K A;  1IPA A;  4PZK A;  4CNG A;  4YQ7 A;  2EGV A;  1ZJR A;  3NK7 A;  1J85 A;  1NS5 A;  3AXZ A;  2QWV A;  4YVJ A;  4KDZ A;  1X7P A;  4CNE A;  3IEF A;  4L69 A;  4YQG A;  4X3M A;  4YPZ A;  2V3K A;  1Z85 A;  1UAK A;  3NK6 A;  3OIN A;  2EGW A;  4X3L A;  4YPW A;  1K3R A;  3AIA A;  4YQO A;  4YQB A;  4YVG A;  5GMC A;  4YQR A;  4YQA A;  4YVH A;  4YQS A;  5GMB A;  3GYQ A;  1P9P A;  4MCB A;  4YVK A;  4CNF A;  1V2X A;  4RG1 A;  1V6Z A;  2O3A A;  4MCC A;  2V3J A;  4YQ6 A;  1UAJ A;  1UAM A;  4YQK A;  1MXI A;  4H3Y A;  1UAL A;  3N4J A;  4KGN A;  4YPX A;  4YQI A;  4YQP A;  4YQ8 A;  2QMM A;  3BBE A;  4CND A;  4YQ2 A;  3QUV A;  3E5Y A;  5GM8 A;  1VHK A;  4YQN A;  3KW2 A;  4YQD A;  4YQ3 A;  5CO4 A;  4FAK A;  3BBH A;  3L8U A;  1OY5 A;  2NWA A;  4YQ4 A;  1NXZ A;  3BBD A; 
#chains in the Genus database with same CATH topology
 4YQL A;  1EUY A;  4JWJ A;  4XBO A;  1X7O A;  3O7B A;  1VHY A;  2RE8 A;  4E8B A;  3KTY A;  4FMW A;  4JAL A;  4YQ5 A;  4JAK A;  2CX8 A;  4MCD A;  4H3S A;  3AI9 X;  2YY8 A;  3DCM X;  1VH0 A;  2HA8 A;  3ONP A;  1QRS A;  1O6D A;  3PIO S;  3IC6 A;  5FAI A;  4JWG A;  4H3Z A;  3OIJ A;  2PNW A;  4YQ0 A;  4WFN S;  4YQT A;  4YQQ A;  4YQC A;  4P2B A;  4YVI A;  3CZB A;  1GZ0 A;  4YPY A;  5D9F A;  4YQ1 A;  3ILK A;  2PI8 A;  4YQ9 A;  2I6D A;  2Z0Y A;  3KNU A;  4YQJ A;  2ZJP S;  1EXD A;  3KY7 A;  3W2V B;  1DFU P;  4IO9 S;  3OII A;  5BNZ A;  4J3C A;  4WFA S;  5IZN A;  5DM6 S;  4IG6 A;  3N4K A;  4H4K A;  3CF5 S;  5JVG S;  1IPA A;  4PZK A;  2ZJQ S;  4IOC S;  4CNG A;  1O0B A;  4YQ7 A;  2RD2 A;  4WFB S;  2EGV A;  1ZJR A;  3NK7 A;  1J85 A;  1NS5 A;  1QRT A;  3AXZ A;  2QWV A;  3DLL S;  4UY8 8;  4YVJ A;  4KDZ A;  1X7P A;  4CNE A;  3IEF A;  4L69 A;  4YQG A;  5JVH S;  4X3M A;  4YPZ A;  2V3K A;  1Z85 A;  1UAK A;  3NK6 A;  5HL7 S;  3OIN A;  2G6G A;  4WCE S;  2EGW A;  3J7Z V;  4X3L A;  5GAG W;  4YPW A;  1K3R A;  3AIA A;  1QRU A;  4IOA S;  4YQO A;  2PIC A;  4YQB A;  4YVG A;  1O0C A;  5GMC A;  4YQR A;  1NYL A;  3W2W B;  1B75 A;  4YQA A;  4YVH A;  4YQS A;  5GMB A;  3GYQ A;  4JXZ A;  1P9P A;  2PJJ A;  4MCB A;  4CNF A;  4YVK A;  4V19 4;  1V2X A;  4RG1 A;  1V6Z A;  1D6K A;  2O3A A;  4JYZ A;  1FEU A;  4MCC A;  4JXX A;  2V3J A;  4U67 S;  4YQ6 A;  1QTQ A;  4WF9 S;  1UAJ A;  1UAM A;  2ZJR S;  4YQK A;  1MXI A;  4H3Y A;  1UDX A;  5GAE W;  1UAL A;  1GTR A;  3N4J A;  4KGN A;  2HZ7 A;  5DM7 S;  4YPX A;  4YQI A;  4YQP A;  3PIP S;  4YQ8 A;  2QMM A;  2G5D A;  3BBE A;  4CND A;  4YQ2 A;  1GTS A;  4JWF A;  3QUV A;  3X1L B;  3E5Y A;  5GM8 A;  2GAE A;  1VHK A;  5GAD W;  1ZJW A;  5GAH W;  4YQN A;  3AII A;  3KW2 A;  1EUQ A;  4YQD A;  2AE0 X;  4YQ3 A;  5CO4 A;  4FAK A;  3BBH A;  3L8U A;  1OY5 A;  2NWA A;  3BBD A;  4JWH A;  4YQ4 A;  1NXZ A;  1TO0 A; 
#chains in the Genus database with same CATH homology
 4YQL A;  4JWJ A;  4XBO A;  1X7O A;  3O7B A;  1VHY A;  4E8B A;  3KTY A;  4FMW A;  4JAL A;  4YQ5 A;  4JAK A;  2CX8 A;  4MCD A;  3AI9 X;  2YY8 A;  3DCM X;  1VH0 A;  2HA8 A;  3ONP A;  1O6D A;  3IC6 A;  5FAI A;  4JWG A;  4H3Z A;  3OIJ A;  4YQ0 A;  4YQT A;  1TO0 A;  4YQQ A;  4YQC A;  4YVI A;  1GZ0 A;  4YPY A;  5D9F A;  4YQ1 A;  3ILK A;  4YQ9 A;  3KNU A;  2I6D A;  2Z0Y A;  4YQJ A;  3KY7 A;  3OII A;  4J3C A;  4IG6 A;  3N4K A;  1IPA A;  4PZK A;  4CNG A;  4YQ7 A;  2EGV A;  1ZJR A;  3NK7 A;  1J85 A;  1NS5 A;  3AXZ A;  2QWV A;  4YVJ A;  4KDZ A;  1X7P A;  4CNE A;  3IEF A;  4L69 A;  4YQG A;  4X3M A;  4YPZ A;  2V3K A;  1Z85 A;  1UAK A;  3NK6 A;  3OIN A;  2EGW A;  4X3L A;  4YPW A;  1K3R A;  3AIA A;  4YQO A;  4YQB A;  4YVG A;  5GMC A;  4YQR A;  4YQA A;  4YVH A;  4YQS A;  5GMB A;  3GYQ A;  1P9P A;  4MCB A;  4YVK A;  4CNF A;  1V2X A;  4RG1 A;  1V6Z A;  2O3A A;  4MCC A;  2V3J A;  4YQ6 A;  1UAJ A;  1UAM A;  4YQK A;  1MXI A;  4H3Y A;  1UAL A;  3N4J A;  4KGN A;  4YPX A;  4YQI A;  4YQP A;  4YQ8 A;  2QMM A;  3BBE A;  4CND A;  4YQ2 A;  4JWF A;  3QUV A;  3E5Y A;  5GM8 A;  1VHK A;  4YQN A;  3KW2 A;  4YQD A;  4YQ3 A;  5CO4 A;  4FAK A;  3BBH A;  3L8U A;  1OY5 A;  2NWA A;  4JWH A;  4YQ4 A;  1NXZ A;  3BBD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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