4E8BA

Crystal structure of 16s rrna methyltransferase rsme from e.coli
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
242
structure length
242
Chain Sequence
IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Ribosomal RNA small subunit methyltransferase E
total genus 72
structure length 242
sequence length 242
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4e8bA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4e8bA02
5GM8A 4X3MA 2YY8A 4YQ7A 2EGWA 3ILKA 4KDZA 4YQJA 4YQDA 4YQAA 1IPAA 3AIAA 3KTYA 3E5YA 4H3ZA 3AXZA 2CX8A 1UALA 3N4KA 4IG6A 1GZ0A 1X7OA 1ZJRA 2Z0YA 4YPWA 1J85A 4YQ0A 4YVKA 1K3RA 3DCMX 4YQGA 1NXZA 1V2XA 4YQKA 4YQLA 4YQNA 1X7PA 4XBOA 4YQQA 5FAIA 4YQ9A 4YQIA 4CNFA 4YVJA 4RG1A 4YPZA 2QWVA 3GYQA 4MCCA 4FAKA 3N4JA 1OY5A 2V3KA 1V6ZA 4YVIA 3KNUA 3KY7A 3OIIA 3NK7A 3NK6A 1TO0A 1NS5A 4YQOA 4E8BA 4YQ6A 4YQ2A 1O6DA 4X3LA 3OIJA 5GMBA 4CNGA 1UAJA 4MCBA 4PZKA 5CO4A 1P9PA 2HA8A 4YQBA 4YQSA 4YPYA 1MXIA 2I6DA 4YQ4A 3BBEA 4YQTA 1VH0A 2EGVA 1UAMA 3BBDA 1Z85A 2O3AA 3L8UA 3AI9X 3IC6A 5D9FA 3QUVA 4JAKA 3KW2A 4YQPA 4YQ5A 4YQ3A 2QMMA 4MCDA 1VHKA 4KGNA 4YQ1A 4J3CA 4YQCA 3OINA 2NWAA 4CNDA 3IEFA 1VHYA 2V3JA 4YQRA 5GMCA 4YQ8A 1UAKA 3BBHA 4CNEA 4YVGA 3ONPA 4JALA 4YVHA 3O7BA 4YPXA 4L69A 4H3YA
chains in the Genus database with same CATH superfamily
4H3SA 5GM8A 4X3MA 2YY8A 4YQ7A 2EGWA 5DM7S 1QRTA 4UY88 3ILKA 4KDZA 4WCES 4YQJA 4JXXA 4YQDA 4YQAA 1IPAA 4V194 3AIAA 3J7ZV 3KTYA 3E5YA 4H3ZA 3AXZA 2CX8A 4JWHA 1UALA 1GTSA 2PI8A 4WF9S 3N4KA 4IG6A 1GZ0A 1X7OA 1ZJRA 5GAGW 2Z0YA 4YPWA 1J85A 2RE8A 4YQ0A 4YVKA 1K3RA 3DCMX 4YQGA 1B75A 4U67S 1NXZA 1V2XA 4JXZA 4YQKA 4YQLA 4YQNA 1X7PA 4IOCS 4XBOA 4YQQA 5FAIA 4JWFA 4YQ9A 5HL7S 4YQIA 3DLLS 4CNFA 3W2VB 4YVJA 1EXDA 4RG1A 4YPZA 2QWVA 3GYQA 4MCCA 4FAKA 3CF5S 4WFAS 2PICA 3N4JA 1DFUP 1OY5A 2V3KA 1V6ZA 4YVIA 5IZNA 3KNUA 3KY7A 3OIIA 3W2WB 3NK7A 2G6GA 2RD2A 3NK6A 1TO0A 1NS5A 3PIOS 5JVHS 4YQOA 4E8BA 4YQ6A 4YQ2A 1O6DA 4X3LA 3OIJA 5GMBA 4CNGA 1UAJA 5DM6S 4P2BA 4MCBA 1FEUA 1QTQA 4JWGA 2AE0X 4PZKA 5CO4A 2HZ7A 2GAEA 1P9PA 2HA8A 4YQBA 4YQSA 4YPYA 1MXIA 4IO9S 2ZJQS 2I6DA 1GTRA 4YQ4A 3BBEA 4YQTA 1EUYA 5JVGS 1VH0A 2G5DA 3PIPS 2EGVA 1UAMA 3BBDA 1Z85A 1O0BA 3X1LB 2O3AA 3L8UA 3AI9X 5GAHW 3IC6A 4JYZA 4WFNS 3QUVA 1O0CA 2PJJA 4FMWA 4JAKA 5D9FA 1QRUA 5GAEW 3KW2A 4YQPA 1EUQA 4YQ5A 4YQ3A 3AIIA 2QMMA 4MCDA 1VHKA 4KGNA 1ZJWA 2PNWA 1D6KA 4J3CA 4YQ1A 1NYLA 3CZBA 2ZJRS 4WFBS 4YQCA 3OINA 2NWAA 4JWJA 4CNDA 3IEFA 2ZJPS 1VHYA 4H4KA 2V3JA 4YQRA 5GMCA 4YQ8A 5GADW 4IOAS 1UAKA 3BBHA 4CNEA 1UDXA 4YVGA 3ONPA 4JALA 5BNZA 4YVHA 3O7BA 4YPXA 1QRSA 4L69A 4H3YA
chains in the Genus database with same CATH topology
5GM8A 4X3MA 2YY8A 4YQ7A 2EGWA 3ILKA 4KDZA 4YQJA 4YQDA 4YQAA 1IPAA 3AIAA 3KTYA 3E5YA 4H3ZA 3AXZA 2CX8A 4JWHA 1UALA 3N4KA 4IG6A 1GZ0A 1X7OA 1ZJRA 2Z0YA 4YPWA 1J85A 4YQ0A 4YVKA 1K3RA 3DCMX 4YQGA 1NXZA 1V2XA 4YQKA 4YQLA 4YQNA 1X7PA 4XBOA 4YQQA 5FAIA 4JWFA 4YQ9A 4YQIA 4CNFA 4YVJA 4RG1A 4YPZA 2QWVA 3GYQA 4MCCA 4FAKA 3N4JA 1OY5A 2V3KA 1V6ZA 4YVIA 3KNUA 3KY7A 3OIIA 3NK7A 3NK6A 1TO0A 1NS5A 4YQOA 4E8BA 4YQ6A 4YQ2A 1O6DA 4X3LA 3OIJA 5GMBA 4CNGA 1UAJA 4MCBA 4JWGA 4PZKA 5CO4A 1P9PA 2HA8A 4YQBA 4YQSA 4YPYA 1MXIA 2I6DA 4YQ4A 3BBEA 4YQTA 1VH0A 2EGVA 1UAMA 3BBDA 1Z85A 2O3AA 3L8UA 3AI9X 3IC6A 5D9FA 4FMWA 3QUVA 4JAKA 3KW2A 4YQPA 4YQ5A 4YQ3A 2QMMA 4MCDA 1VHKA 4KGNA 4YQ1A 4J3CA 4YQCA 3OINA 2NWAA 4JWJA 4CNDA 3IEFA 1VHYA 2V3JA 4YQRA 5GMCA 4YQ8A 1UAKA 3BBHA 4CNEA 4YVGA 3ONPA 4JALA 4YVHA 3O7BA 4YPXA 4L69A 4H3YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GM8 A;  4X3M A;  2YY8 A;  4YQ7 A;  2EGW A;  3ILK A;  4KDZ A;  4YQJ A;  4YQD A;  4YQA A;  1IPA A;  3AIA A;  3KTY A;  3E5Y A;  4H3Z A;  3AXZ A;  2CX8 A;  1UAL A;  3N4K A;  4IG6 A;  1GZ0 A;  1X7O A;  1ZJR A;  2Z0Y A;  4YPW A;  1J85 A;  4YQ0 A;  4YVK A;  1K3R A;  3DCM X;  4YQG A;  1NXZ A;  1V2X A;  4YQK A;  4YQL A;  4YQN A;  1X7P A;  4XBO A;  4YQQ A;  5FAI A;  4YQ9 A;  4YQI A;  4CNF A;  4YVJ A;  4RG1 A;  4YPZ A;  2QWV A;  3GYQ A;  4MCC A;  4FAK A;  3N4J A;  1OY5 A;  2V3K A;  1V6Z A;  4YVI A;  3KNU A;  3KY7 A;  3OII A;  3NK7 A;  3NK6 A;  1TO0 A;  1NS5 A;  4YQO A;  4E8B A;  4YQ6 A;  4YQ2 A;  1O6D A;  4X3L A;  3OIJ A;  5GMB A;  4CNG A;  1UAJ A;  4MCB A;  4PZK A;  5CO4 A;  1P9P A;  2HA8 A;  4YQB A;  4YQS A;  4YPY A;  1MXI A;  2I6D A;  4YQ4 A;  3BBE A;  4YQT A;  1VH0 A;  2EGV A;  1UAM A;  3BBD A;  1Z85 A;  2O3A A;  3L8U A;  3AI9 X;  3IC6 A;  5D9F A;  3QUV A;  4JAK A;  3KW2 A;  4YQP A;  4YQ5 A;  4YQ3 A;  2QMM A;  4MCD A;  1VHK A;  4KGN A;  4YQ1 A;  4J3C A;  4YQC A;  3OIN A;  2NWA A;  4CND A;  3IEF A;  1VHY A;  2V3J A;  4YQR A;  5GMC A;  4YQ8 A;  1UAK A;  3BBH A;  4CNE A;  4YVG A;  3ONP A;  4JAL A;  4YVH A;  3O7B A;  4YPX A;  4L69 A;  4H3Y A; 
#chains in the Genus database with same CATH topology
 4H3S A;  5GM8 A;  4X3M A;  2YY8 A;  4YQ7 A;  2EGW A;  5DM7 S;  1QRT A;  4UY8 8;  3ILK A;  4KDZ A;  4WCE S;  4YQJ A;  4JXX A;  4YQD A;  4YQA A;  1IPA A;  4V19 4;  3AIA A;  3J7Z V;  3KTY A;  3E5Y A;  4H3Z A;  3AXZ A;  2CX8 A;  4JWH A;  1UAL A;  1GTS A;  2PI8 A;  4WF9 S;  3N4K A;  4IG6 A;  1GZ0 A;  1X7O A;  1ZJR A;  5GAG W;  2Z0Y A;  4YPW A;  1J85 A;  2RE8 A;  4YQ0 A;  4YVK A;  1K3R A;  3DCM X;  4YQG A;  1B75 A;  4U67 S;  1NXZ A;  1V2X A;  4JXZ A;  4YQK A;  4YQL A;  4YQN A;  1X7P A;  4IOC S;  4XBO A;  4YQQ A;  5FAI A;  4JWF A;  4YQ9 A;  5HL7 S;  4YQI A;  3DLL S;  4CNF A;  3W2V B;  4YVJ A;  1EXD A;  4RG1 A;  4YPZ A;  2QWV A;  3GYQ A;  4MCC A;  4FAK A;  3CF5 S;  4WFA S;  2PIC A;  3N4J A;  1DFU P;  1OY5 A;  2V3K A;  1V6Z A;  4YVI A;  5IZN A;  3KNU A;  3KY7 A;  3OII A;  3W2W B;  3NK7 A;  2G6G A;  2RD2 A;  3NK6 A;  1TO0 A;  1NS5 A;  3PIO S;  5JVH S;  4YQO A;  4E8B A;  4YQ6 A;  4YQ2 A;  1O6D A;  4X3L A;  3OIJ A;  5GMB A;  4CNG A;  1UAJ A;  5DM6 S;  4P2B A;  4MCB A;  1FEU A;  1QTQ A;  4JWG A;  2AE0 X;  4PZK A;  5CO4 A;  2HZ7 A;  2GAE A;  1P9P A;  2HA8 A;  4YQB A;  4YQS A;  4YPY A;  1MXI A;  4IO9 S;  2ZJQ S;  2I6D A;  1GTR A;  4YQ4 A;  3BBE A;  4YQT A;  1EUY A;  5JVG S;  1VH0 A;  2G5D A;  3PIP S;  2EGV A;  1UAM A;  3BBD A;  1Z85 A;  1O0B A;  3X1L B;  2O3A A;  3L8U A;  3AI9 X;  5GAH W;  3IC6 A;  4JYZ A;  4WFN S;  3QUV A;  1O0C A;  2PJJ A;  4FMW A;  4JAK A;  5D9F A;  1QRU A;  5GAE W;  3KW2 A;  4YQP A;  1EUQ A;  4YQ5 A;  4YQ3 A;  3AII A;  2QMM A;  4MCD A;  1VHK A;  4KGN A;  1ZJW A;  2PNW A;  1D6K A;  4J3C A;  4YQ1 A;  1NYL A;  3CZB A;  2ZJR S;  4WFB S;  4YQC A;  3OIN A;  2NWA A;  4JWJ A;  4CND A;  3IEF A;  2ZJP S;  1VHY A;  4H4K A;  2V3J A;  4YQR A;  5GMC A;  4YQ8 A;  5GAD W;  4IOA S;  1UAK A;  3BBH A;  4CNE A;  1UDX A;  4YVG A;  3ONP A;  4JAL A;  5BNZ A;  4YVH A;  3O7B A;  4YPX A;  1QRS A;  4L69 A;  4H3Y A; 
#chains in the Genus database with same CATH homology
 5GM8 A;  4X3M A;  2YY8 A;  4YQ7 A;  2EGW A;  3ILK A;  4KDZ A;  4YQJ A;  4YQD A;  4YQA A;  1IPA A;  3AIA A;  3KTY A;  3E5Y A;  4H3Z A;  3AXZ A;  2CX8 A;  4JWH A;  1UAL A;  3N4K A;  4IG6 A;  1GZ0 A;  1X7O A;  1ZJR A;  2Z0Y A;  4YPW A;  1J85 A;  4YQ0 A;  4YVK A;  1K3R A;  3DCM X;  4YQG A;  1NXZ A;  1V2X A;  4YQK A;  4YQL A;  4YQN A;  1X7P A;  4XBO A;  4YQQ A;  5FAI A;  4JWF A;  4YQ9 A;  4YQI A;  4CNF A;  4YVJ A;  4RG1 A;  4YPZ A;  2QWV A;  3GYQ A;  4MCC A;  4FAK A;  3N4J A;  1OY5 A;  2V3K A;  1V6Z A;  4YVI A;  3KNU A;  3KY7 A;  3OII A;  3NK7 A;  3NK6 A;  1TO0 A;  1NS5 A;  4YQO A;  4E8B A;  4YQ6 A;  4YQ2 A;  1O6D A;  4X3L A;  3OIJ A;  5GMB A;  4CNG A;  1UAJ A;  4MCB A;  4JWG A;  4PZK A;  5CO4 A;  1P9P A;  2HA8 A;  4YQB A;  4YQS A;  4YPY A;  1MXI A;  2I6D A;  4YQ4 A;  3BBE A;  4YQT A;  1VH0 A;  2EGV A;  1UAM A;  3BBD A;  1Z85 A;  2O3A A;  3L8U A;  3AI9 X;  3IC6 A;  5D9F A;  4FMW A;  3QUV A;  4JAK A;  3KW2 A;  4YQP A;  4YQ5 A;  4YQ3 A;  2QMM A;  4MCD A;  1VHK A;  4KGN A;  4YQ1 A;  4J3C A;  4YQC A;  3OIN A;  2NWA A;  4JWJ A;  4CND A;  3IEF A;  1VHY A;  2V3J A;  4YQR A;  5GMC A;  4YQ8 A;  1UAK A;  3BBH A;  4CNE A;  4YVG A;  3ONP A;  4JAL A;  4YVH A;  3O7B A;  4YPX A;  4L69 A;  4H3Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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