4E8BA

Crystal structure of 16s rrna methyltransferase rsme from e.coli
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
242
structure length
242
Chain Sequence
IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Ribosomal RNA small subunit methyltransferase E
total genus 72
structure length 242
sequence length 242
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4e8bA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4e8bA02
4CNFA 3AXZA 2Z0YA 4IG6A 4YQOA 1IPAA 1OY5A 1V2XA 3OINA 4YQNA 2NWAA 1MXIA 3N4KA 4CNDA 4MCCA 1O6DA 3E5YA 4YQ8A 1UAMA 3AI9X 4FAKA 4YQ4A 1VHYA 5GMCA 2EGWA 4YQ7A 5FAIA 1UAKA 1V6ZA 4YQGA 2QMMA 2YY8A 4JALA 4YQIA 1J85A 4YQ9A 4YQLA 5GM8A 4L69A 4H3YA 3AIAA 4YQDA 4YQRA 3N4JA 4XBOA 4YQBA 5D9FA 4YPXA 3IC6A 4KDZA 4YQPA 4YPYA 1TO0A 4YQ6A 1VH0A 5GMBA 3L8UA 2V3KA 4J3CA 3O7BA 1UAJA 3IEFA 5CO4A 1P9PA 3BBHA 2HA8A 3OIJA 4X3MA 3BBDA 4YQ0A 1GZ0A 1UALA 4KGNA 1ZJRA 1NS5A 4YVJA 4YVKA 4YVIA 2QWVA 3BBEA 4YQ1A 4YQCA 4YQSA 4YQ5A 3NK7A 1VHKA 4PZKA 4YVHA 1K3RA 4YPWA 3KW2A 3OIIA 4YQ3A 4JAKA 4YQKA 4H3ZA 2EGVA 4YQ2A 4CNEA 3KNUA 2V3JA 4RG1A 4E8BA 3GYQA 1Z85A 3KY7A 2CX8A 2I6DA 4YQQA 3ONPA 4YQAA 3DCMX 4YVGA 4CNGA 2O3AA 4MCDA 3ILKA 3KTYA 1X7PA 3QUVA 4YPZA 4YQTA 4YQJA 4MCBA 3NK6A 4X3LA 1X7OA 1NXZA
chains in the Genus database with same CATH superfamily
4CNFA 3AXZA 2Z0YA 4FMWA 4IG6A 4YQOA 1IPAA 1OY5A 1V2XA 3OINA 4WFAS 4V194 3CZBA 4YQNA 2NWAA 1MXIA 3N4KA 4CNDA 4WCES 2ZJRS 1GTSA 4MCCA 1O6DA 3E5YA 4YQ8A 1UAMA 1QTQA 1EUQA 3AI9X 4FAKA 5IZNA 4YQ4A 1VHYA 1O0BA 5GMCA 2EGWA 1FEUA 4YQ7A 5FAIA 3DLLS 1EUYA 1QRUA 1UAKA 1V6ZA 5DM6S 4YQGA 4JYZA 2QMMA 5GAHW 2YY8A 4JALA 4JXZA 4YQIA 1J85A 4YQ9A 4YQLA 5GM8A 4L69A 4IOCS 4H3YA 2PJJA 4WF9S 3AIAA 4H4KA 4UY88 4YQDA 4YQRA 3N4JA 4XBOA 2RD2A 4YQBA 5D9FA 4YPXA 3IC6A 4KDZA 4YQPA 3CF5S 4YPYA 5JVGS 1NYLA 1D6KA 1TO0A 4YQ6A 3W2VB 1VH0A 5GMBA 1ZJWA 4JWHA 4IO9S 3L8UA 2V3KA 4J3CA 3O7BA 2ZJQS 1UAJA 1B75A 1P9PA 3IEFA 5CO4A 4H3SA 5GAGW 5HL7S 1GTRA 1UDXA 3BBHA 2HA8A 2HZ7A 3OIJA 4X3MA 3J7ZV 3BBDA 4YQ0A 2PNWA 1GZ0A 1UALA 4KGNA 3AIIA 1ZJRA 4JWJA 1NS5A 1QRSA 4YVJA 5DM7S 5GAEW 4YVKA 1QRTA 2QWVA 4YVIA 2AE0X 3BBEA 4YQ1A 4YQCA 4WFNS 4YQSA 4YQ5A 3NK7A 4JXXA 1VHKA 4PZKA 1DFUP 5GADW 1K3RA 4YVHA 4YPWA 3KW2A 3OIIA 4U67S 1NXZA 4YQ3A 5BNZA 4JAKA 4YQKA 4H3ZA 2EGVA 2PI8A 4YQ2A 3PIPS 4CNEA 1O0CA 4JWGA 5JVHS 3KNUA 2V3JA 4RG1A 2G5DA 4E8BA 3GYQA 4JWFA 3PIOS 1Z85A 2ZJPS 3KY7A 2CX8A 3W2WB 2I6DA 4YQQA 4WFBS 4IOAS 3ONPA 4YQAA 2GAEA 3DCMX 2RE8A 2O3AA 4YVGA 4CNGA 3X1LB 4MCDA 3ILKA 3KTYA 1X7PA 3QUVA 1EXDA 4YPZA 4YQTA 4YQJA 2G6GA 4MCBA 3NK6A 2PICA 4X3LA 1X7OA 4P2BA
chains in the Genus database with same CATH topology
4CNFA 3AXZA 2Z0YA 4FMWA 4IG6A 4YQOA 1IPAA 1OY5A 1V2XA 3OINA 4YQNA 2NWAA 1MXIA 3N4KA 4CNDA 4MCCA 1O6DA 3E5YA 4YQ8A 1UAMA 3AI9X 4FAKA 4YQ4A 1VHYA 5GMCA 2EGWA 4YQ7A 5FAIA 1UAKA 1V6ZA 4YQGA 2QMMA 2YY8A 4JALA 4YQIA 1J85A 4YQ9A 4YQLA 5GM8A 4L69A 4H3YA 3AIAA 4YQDA 4YQRA 3N4JA 4XBOA 4YQBA 5D9FA 4YPXA 3IC6A 4KDZA 4YQPA 4YPYA 1TO0A 4YQ6A 1VH0A 5GMBA 4JWHA 3L8UA 2V3KA 4J3CA 3O7BA 1UAJA 3IEFA 5CO4A 1P9PA 3BBHA 2HA8A 3OIJA 4X3MA 3BBDA 4YQ0A 1GZ0A 1UALA 4KGNA 1ZJRA 4JWJA 1NS5A 4YVJA 4YVKA 4YVIA 2QWVA 3BBEA 4YQ1A 4YQCA 4YQSA 4YQ5A 3NK7A 1VHKA 4PZKA 4YVHA 1K3RA 4YPWA 3KW2A 3OIIA 4YQ3A 4JAKA 4YQKA 4H3ZA 2EGVA 4YQ2A 4CNEA 4JWGA 3KNUA 2V3JA 4RG1A 4E8BA 3GYQA 4JWFA 1Z85A 3KY7A 2CX8A 2I6DA 4YQQA 3ONPA 4YQAA 3DCMX 4YVGA 4CNGA 2O3AA 4MCDA 3ILKA 3KTYA 1X7PA 3QUVA 4YPZA 4YQTA 4YQJA 4MCBA 3NK6A 4X3LA 1X7OA 1NXZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CNF A;  3AXZ A;  2Z0Y A;  4IG6 A;  4YQO A;  1IPA A;  1OY5 A;  1V2X A;  3OIN A;  4YQN A;  2NWA A;  1MXI A;  3N4K A;  4CND A;  4MCC A;  1O6D A;  3E5Y A;  4YQ8 A;  1UAM A;  3AI9 X;  4FAK A;  4YQ4 A;  1VHY A;  5GMC A;  2EGW A;  4YQ7 A;  5FAI A;  1UAK A;  1V6Z A;  4YQG A;  2QMM A;  2YY8 A;  4JAL A;  4YQI A;  1J85 A;  4YQ9 A;  4YQL A;  5GM8 A;  4L69 A;  4H3Y A;  3AIA A;  4YQD A;  4YQR A;  3N4J A;  4XBO A;  4YQB A;  5D9F A;  4YPX A;  3IC6 A;  4KDZ A;  4YQP A;  4YPY A;  1TO0 A;  4YQ6 A;  1VH0 A;  5GMB A;  3L8U A;  2V3K A;  4J3C A;  3O7B A;  1UAJ A;  3IEF A;  5CO4 A;  1P9P A;  3BBH A;  2HA8 A;  3OIJ A;  4X3M A;  3BBD A;  4YQ0 A;  1GZ0 A;  1UAL A;  4KGN A;  1ZJR A;  1NS5 A;  4YVJ A;  4YVK A;  4YVI A;  2QWV A;  3BBE A;  4YQ1 A;  4YQC A;  4YQS A;  4YQ5 A;  3NK7 A;  1VHK A;  4PZK A;  4YVH A;  1K3R A;  4YPW A;  3KW2 A;  3OII A;  4YQ3 A;  4JAK A;  4YQK A;  4H3Z A;  2EGV A;  4YQ2 A;  4CNE A;  3KNU A;  2V3J A;  4RG1 A;  4E8B A;  3GYQ A;  1Z85 A;  3KY7 A;  2CX8 A;  2I6D A;  4YQQ A;  3ONP A;  4YQA A;  3DCM X;  4YVG A;  4CNG A;  2O3A A;  4MCD A;  3ILK A;  3KTY A;  1X7P A;  3QUV A;  4YPZ A;  4YQT A;  4YQJ A;  4MCB A;  3NK6 A;  4X3L A;  1X7O A;  1NXZ A; 
#chains in the Genus database with same CATH topology
 4CNF A;  3AXZ A;  2Z0Y A;  4FMW A;  4IG6 A;  4YQO A;  1IPA A;  1OY5 A;  1V2X A;  3OIN A;  4WFA S;  4V19 4;  3CZB A;  4YQN A;  2NWA A;  1MXI A;  3N4K A;  4CND A;  4WCE S;  2ZJR S;  1GTS A;  4MCC A;  1O6D A;  3E5Y A;  4YQ8 A;  1UAM A;  1QTQ A;  1EUQ A;  3AI9 X;  4FAK A;  5IZN A;  4YQ4 A;  1VHY A;  1O0B A;  5GMC A;  2EGW A;  1FEU A;  4YQ7 A;  5FAI A;  3DLL S;  1EUY A;  1QRU A;  1UAK A;  1V6Z A;  5DM6 S;  4YQG A;  4JYZ A;  2QMM A;  5GAH W;  2YY8 A;  4JAL A;  4JXZ A;  4YQI A;  1J85 A;  4YQ9 A;  4YQL A;  5GM8 A;  4L69 A;  4IOC S;  4H3Y A;  2PJJ A;  4WF9 S;  3AIA A;  4H4K A;  4UY8 8;  4YQD A;  4YQR A;  3N4J A;  4XBO A;  2RD2 A;  4YQB A;  5D9F A;  4YPX A;  3IC6 A;  4KDZ A;  4YQP A;  3CF5 S;  4YPY A;  5JVG S;  1NYL A;  1D6K A;  1TO0 A;  4YQ6 A;  3W2V B;  1VH0 A;  5GMB A;  1ZJW A;  4JWH A;  4IO9 S;  3L8U A;  2V3K A;  4J3C A;  3O7B A;  2ZJQ S;  1UAJ A;  1B75 A;  1P9P A;  3IEF A;  5CO4 A;  4H3S A;  5GAG W;  5HL7 S;  1GTR A;  1UDX A;  3BBH A;  2HA8 A;  2HZ7 A;  3OIJ A;  4X3M A;  3J7Z V;  3BBD A;  4YQ0 A;  2PNW A;  1GZ0 A;  1UAL A;  4KGN A;  3AII A;  1ZJR A;  4JWJ A;  1NS5 A;  1QRS A;  4YVJ A;  5DM7 S;  5GAE W;  4YVK A;  1QRT A;  2QWV A;  4YVI A;  2AE0 X;  3BBE A;  4YQ1 A;  4YQC A;  4WFN S;  4YQS A;  4YQ5 A;  3NK7 A;  4JXX A;  1VHK A;  4PZK A;  1DFU P;  5GAD W;  1K3R A;  4YVH A;  4YPW A;  3KW2 A;  3OII A;  4U67 S;  1NXZ A;  4YQ3 A;  5BNZ A;  4JAK A;  4YQK A;  4H3Z A;  2EGV A;  2PI8 A;  4YQ2 A;  3PIP S;  4CNE A;  1O0C A;  4JWG A;  5JVH S;  3KNU A;  2V3J A;  4RG1 A;  2G5D A;  4E8B A;  3GYQ A;  4JWF A;  3PIO S;  1Z85 A;  2ZJP S;  3KY7 A;  2CX8 A;  3W2W B;  2I6D A;  4YQQ A;  4WFB S;  4IOA S;  3ONP A;  4YQA A;  2GAE A;  3DCM X;  2RE8 A;  2O3A A;  4YVG A;  4CNG A;  3X1L B;  4MCD A;  3ILK A;  3KTY A;  1X7P A;  3QUV A;  1EXD A;  4YPZ A;  4YQT A;  4YQJ A;  2G6G A;  4MCB A;  3NK6 A;  2PIC A;  4X3L A;  1X7O A;  4P2B A; 
#chains in the Genus database with same CATH homology
 4CNF A;  3AXZ A;  2Z0Y A;  4FMW A;  4IG6 A;  4YQO A;  1IPA A;  1OY5 A;  1V2X A;  3OIN A;  4YQN A;  2NWA A;  1MXI A;  3N4K A;  4CND A;  4MCC A;  1O6D A;  3E5Y A;  4YQ8 A;  1UAM A;  3AI9 X;  4FAK A;  4YQ4 A;  1VHY A;  5GMC A;  2EGW A;  4YQ7 A;  5FAI A;  1UAK A;  1V6Z A;  4YQG A;  2QMM A;  2YY8 A;  4JAL A;  4YQI A;  1J85 A;  4YQ9 A;  4YQL A;  5GM8 A;  4L69 A;  4H3Y A;  3AIA A;  4YQD A;  4YQR A;  3N4J A;  4XBO A;  4YQB A;  5D9F A;  4YPX A;  3IC6 A;  4KDZ A;  4YQP A;  4YPY A;  1TO0 A;  4YQ6 A;  1VH0 A;  5GMB A;  4JWH A;  3L8U A;  2V3K A;  4J3C A;  3O7B A;  1UAJ A;  3IEF A;  5CO4 A;  1P9P A;  3BBH A;  2HA8 A;  3OIJ A;  4X3M A;  3BBD A;  4YQ0 A;  1GZ0 A;  1UAL A;  4KGN A;  1ZJR A;  4JWJ A;  1NS5 A;  4YVJ A;  4YVK A;  4YVI A;  2QWV A;  3BBE A;  4YQ1 A;  4YQC A;  4YQS A;  4YQ5 A;  3NK7 A;  1VHK A;  4PZK A;  4YVH A;  1K3R A;  4YPW A;  3KW2 A;  3OII A;  4YQ3 A;  4JAK A;  4YQK A;  4H3Z A;  2EGV A;  4YQ2 A;  4CNE A;  4JWG A;  3KNU A;  2V3J A;  4RG1 A;  4E8B A;  3GYQ A;  4JWF A;  1Z85 A;  3KY7 A;  2CX8 A;  2I6D A;  4YQQ A;  3ONP A;  4YQA A;  3DCM X;  4YVG A;  4CNG A;  2O3A A;  4MCD A;  3ILK A;  3KTY A;  1X7P A;  3QUV A;  4YPZ A;  4YQT A;  4YQJ A;  4MCB A;  3NK6 A;  4X3L A;  1X7O A;  1NXZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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