4L69A

Rv2372c of mycobacterium tuberculosis is rsme like methyltransferse
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
247
structure length
244
Chain Sequence
VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords Ribosomal RNA small subunit methyltransferase E
total genus 66
structure length 244
sequence length 247
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4l69A01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4l69A02
3N4KA 4YQ4A 3GYQA 2EGVA 2QMMA 3L8UA 5CO4A 1Z85A 3KNUA 4PZKA 1VHYA 3QUVA 4YQOA 3OIIA 4CNDA 1ZJRA 1UAKA 4YQRA 4E8BA 3KTYA 3KW2A 1GZ0A 3NK7A 3E5YA 4X3MA 5FAIA 1NXZA 4YVKA 4X3LA 3IC6A 4YPXA 4JAKA 5GMCA 4YQ6A 1MXIA 4RG1A 1K3RA 4YQQA 1OY5A 1J85A 4YVIA 2V3JA 4YVGA 4YPWA 4YQLA 1P9PA 3ONPA 4YQPA 4YQCA 4MCDA 4IG6A 3AXZA 4H3ZA 1X7OA 4YQ5A 4KDZA 4YQ7A 3AIAA 2NWAA 1UAJA 4YQGA 4FAKA 3BBHA 4YQ2A 4YQSA 4YQTA 3N4JA 4JALA 3OINA 4CNFA 3BBEA 1X7PA 3ILKA 2V3KA 5GMBA 4YQ8A 4YQIA 3AI9X 4YPYA 4YQAA 1IPAA 3NK6A 4YQ9A 5D9FA 4MCCA 4YQBA 4MCBA 4XBOA 4YQNA 4YQ3A 1O6DA 3IEFA 4H3YA 1VHKA 4KGNA 1NS5A 4YQJA 2EGWA 2QWVA 2I6DA 3KY7A 4YVJA 2O3AA 4YQKA 4YVHA 3OIJA 1TO0A 2HA8A 2CX8A 4CNEA 5GM8A 4CNGA 2YY8A 3O7BA 3DCMX 1UALA 4YQ1A 1V6ZA 2Z0YA 1V2XA 4L69A 1VH0A 4YQDA 4YQ0A 1UAMA 4YPZA 4J3CA 3BBDA
chains in the Genus database with same CATH superfamily
3N4KA 4YQ4A 2G6GA 3GYQA 2EGVA 4IOCS 4UY88 1NYLA 2QMMA 5DM7S 3L8UA 5CO4A 1Z85A 4JWJA 3KNUA 4PZKA 1VHYA 2PNWA 3QUVA 4JWGA 4YQOA 3W2WB 3OIIA 4CNDA 1ZJRA 2PICA 3CF5S 1UAKA 4YQRA 4E8BA 3KTYA 3KW2A 4WCES 1GZ0A 3NK7A 5GAGW 3E5YA 4X3MA 5FAIA 1NXZA 4YVKA 1UDXA 3IC6A 4X3LA 1ZJWA 4YPXA 4JAKA 5GMCA 4YQ6A 1MXIA 1K3RA 4H4KA 4RG1A 4YQQA 4WFBS 1OY5A 1J85A 4YVIA 2V3JA 4P2BA 2RD2A 4YVGA 4YPWA 4YQLA 1P9PA 3ONPA 3DLLS 1O0BA 1QTQA 4YQPA 4WFAS 4YQCA 4MCDA 4IG6A 3AXZA 4H3ZA 1X7OA 4YQ5A 1QRUA 4KDZA 1FEUA 3AIAA 5IZNA 2NWAA 1EXDA 4YQ7A 1UAJA 4YQGA 4FAKA 3BBHA 4JWFA 4YQ2A 4YQSA 4YQTA 5DM6S 3N4JA 4JALA 1D6KA 3OINA 2ZJRS 4CNFA 3BBEA 1X7PA 2V3KA 3ILKA 5GADW 5GMBA 4YQ8A 4YQIA 3PIOS 3AI9X 4YPYA 2PI8A 4YQAA 3AIIA 5JVHS 4V194 1IPAA 3NK6A 4YQ9A 1EUYA 3PIPS 2RE8A 4JWHA 2G5DA 5D9FA 4MCCA 1B75A 4YQBA 1EUQA 2HZ7A 2GAEA 3X1LB 4IOAS 3CZBA 1GTRA 4MCBA 4XBOA 2ZJPS 2PJJA 2ZJQS 4JXXA 1O0CA 4YQNA 4YQ3A 1O6DA 4JXZA 4JYZA 3IEFA 4H3YA 4H3SA 1VHKA 4U67S 4KGNA 1NS5A 4YQJA 2EGWA 1QRTA 2QWVA 2I6DA 3KY7A 4YVJA 4WFNS 2O3AA 4YQKA 4YVHA 3OIJA 1TO0A 5GAHW 4IO9S 4WF9S 2HA8A 2CX8A 4CNEA 1GTSA 5GM8A 3W2VB 4CNGA 2YY8A 1QRSA 5BNZA 3O7BA 1DFUP 3DCMX 5GAEW 5HL7S 1UALA 2AE0X 3J7ZV 1V6ZA 4YQ1A 2Z0YA 1V2XA 4L69A 4FMWA 1VH0A 4YQDA 4YQ0A 1UAMA 4YPZA 4J3CA 5JVGS 3BBDA
chains in the Genus database with same CATH topology
3N4KA 4YQ4A 3GYQA 2EGVA 2QMMA 3L8UA 5CO4A 1Z85A 4JWJA 3KNUA 4PZKA 1VHYA 3QUVA 4JWGA 4YQOA 3OIIA 4CNDA 1ZJRA 1UAKA 4YQRA 4E8BA 3KTYA 3KW2A 1GZ0A 3NK7A 3E5YA 4X3MA 5FAIA 1NXZA 4YVKA 4X3LA 3IC6A 4YPXA 4JAKA 5GMCA 4YQ6A 1MXIA 1K3RA 4RG1A 4YQQA 1OY5A 1J85A 4YVIA 2V3JA 4YVGA 4YPWA 4YQLA 1P9PA 3ONPA 4YQPA 4YQCA 4MCDA 4IG6A 3AXZA 4H3ZA 1X7OA 4YQ5A 4KDZA 4YQ7A 3AIAA 2NWAA 1UAJA 4YQGA 4FAKA 3BBHA 4JWFA 4YQ2A 4YQSA 4YQTA 3N4JA 4JALA 3OINA 4CNFA 3BBEA 1X7PA 3ILKA 2V3KA 5GMBA 4YQ8A 4YQIA 3AI9X 4YPYA 4YQAA 1IPAA 3NK6A 4YQ9A 4JWHA 5D9FA 4MCCA 4YQBA 4MCBA 4XBOA 4YQNA 4YQ3A 1O6DA 3IEFA 4H3YA 1VHKA 4KGNA 1NS5A 4YQJA 2EGWA 2QWVA 2I6DA 3KY7A 4YVJA 2O3AA 4YQKA 4YVHA 3OIJA 1TO0A 2HA8A 2CX8A 4CNEA 5GM8A 4CNGA 2YY8A 3O7BA 3DCMX 1UALA 4YQ1A 1V6ZA 2Z0YA 1V2XA 4L69A 1VH0A 4YQDA 4YQ0A 1UAMA 4YPZA 4J3CA 4FMWA 3BBDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N4K A;  4YQ4 A;  3GYQ A;  2EGV A;  2QMM A;  3L8U A;  5CO4 A;  1Z85 A;  3KNU A;  4PZK A;  1VHY A;  3QUV A;  4YQO A;  3OII A;  4CND A;  1ZJR A;  1UAK A;  4YQR A;  4E8B A;  3KTY A;  3KW2 A;  1GZ0 A;  3NK7 A;  3E5Y A;  4X3M A;  5FAI A;  1NXZ A;  4YVK A;  4X3L A;  3IC6 A;  4YPX A;  4JAK A;  5GMC A;  4YQ6 A;  1MXI A;  4RG1 A;  1K3R A;  4YQQ A;  1OY5 A;  1J85 A;  4YVI A;  2V3J A;  4YVG A;  4YPW A;  4YQL A;  1P9P A;  3ONP A;  4YQP A;  4YQC A;  4MCD A;  4IG6 A;  3AXZ A;  4H3Z A;  1X7O A;  4YQ5 A;  4KDZ A;  4YQ7 A;  3AIA A;  2NWA A;  1UAJ A;  4YQG A;  4FAK A;  3BBH A;  4YQ2 A;  4YQS A;  4YQT A;  3N4J A;  4JAL A;  3OIN A;  4CNF A;  3BBE A;  1X7P A;  3ILK A;  2V3K A;  5GMB A;  4YQ8 A;  4YQI A;  3AI9 X;  4YPY A;  4YQA A;  1IPA A;  3NK6 A;  4YQ9 A;  5D9F A;  4MCC A;  4YQB A;  4MCB A;  4XBO A;  4YQN A;  4YQ3 A;  1O6D A;  3IEF A;  4H3Y A;  1VHK A;  4KGN A;  1NS5 A;  4YQJ A;  2EGW A;  2QWV A;  2I6D A;  3KY7 A;  4YVJ A;  2O3A A;  4YQK A;  4YVH A;  3OIJ A;  1TO0 A;  2HA8 A;  2CX8 A;  4CNE A;  5GM8 A;  4CNG A;  2YY8 A;  3O7B A;  3DCM X;  1UAL A;  4YQ1 A;  1V6Z A;  2Z0Y A;  1V2X A;  4L69 A;  1VH0 A;  4YQD A;  4YQ0 A;  1UAM A;  4YPZ A;  4J3C A;  3BBD A; 
#chains in the Genus database with same CATH topology
 3N4K A;  4YQ4 A;  2G6G A;  3GYQ A;  2EGV A;  4IOC S;  4UY8 8;  1NYL A;  2QMM A;  5DM7 S;  3L8U A;  5CO4 A;  1Z85 A;  4JWJ A;  3KNU A;  4PZK A;  1VHY A;  2PNW A;  3QUV A;  4JWG A;  4YQO A;  3W2W B;  3OII A;  4CND A;  1ZJR A;  2PIC A;  3CF5 S;  1UAK A;  4YQR A;  4E8B A;  3KTY A;  3KW2 A;  4WCE S;  1GZ0 A;  3NK7 A;  5GAG W;  3E5Y A;  4X3M A;  5FAI A;  1NXZ A;  4YVK A;  1UDX A;  3IC6 A;  4X3L A;  1ZJW A;  4YPX A;  4JAK A;  5GMC A;  4YQ6 A;  1MXI A;  1K3R A;  4H4K A;  4RG1 A;  4YQQ A;  4WFB S;  1OY5 A;  1J85 A;  4YVI A;  2V3J A;  4P2B A;  2RD2 A;  4YVG A;  4YPW A;  4YQL A;  1P9P A;  3ONP A;  3DLL S;  1O0B A;  1QTQ A;  4YQP A;  4WFA S;  4YQC A;  4MCD A;  4IG6 A;  3AXZ A;  4H3Z A;  1X7O A;  4YQ5 A;  1QRU A;  4KDZ A;  1FEU A;  3AIA A;  5IZN A;  2NWA A;  1EXD A;  4YQ7 A;  1UAJ A;  4YQG A;  4FAK A;  3BBH A;  4JWF A;  4YQ2 A;  4YQS A;  4YQT A;  5DM6 S;  3N4J A;  4JAL A;  1D6K A;  3OIN A;  2ZJR S;  4CNF A;  3BBE A;  1X7P A;  2V3K A;  3ILK A;  5GAD W;  5GMB A;  4YQ8 A;  4YQI A;  3PIO S;  3AI9 X;  4YPY A;  2PI8 A;  4YQA A;  3AII A;  5JVH S;  4V19 4;  1IPA A;  3NK6 A;  4YQ9 A;  1EUY A;  3PIP S;  2RE8 A;  4JWH A;  2G5D A;  5D9F A;  4MCC A;  1B75 A;  4YQB A;  1EUQ A;  2HZ7 A;  2GAE A;  3X1L B;  4IOA S;  3CZB A;  1GTR A;  4MCB A;  4XBO A;  2ZJP S;  2PJJ A;  2ZJQ S;  4JXX A;  1O0C A;  4YQN A;  4YQ3 A;  1O6D A;  4JXZ A;  4JYZ A;  3IEF A;  4H3Y A;  4H3S A;  1VHK A;  4U67 S;  4KGN A;  1NS5 A;  4YQJ A;  2EGW A;  1QRT A;  2QWV A;  2I6D A;  3KY7 A;  4YVJ A;  4WFN S;  2O3A A;  4YQK A;  4YVH A;  3OIJ A;  1TO0 A;  5GAH W;  4IO9 S;  4WF9 S;  2HA8 A;  2CX8 A;  4CNE A;  1GTS A;  5GM8 A;  3W2V B;  4CNG A;  2YY8 A;  1QRS A;  5BNZ A;  3O7B A;  1DFU P;  3DCM X;  5GAE W;  5HL7 S;  1UAL A;  2AE0 X;  3J7Z V;  1V6Z A;  4YQ1 A;  2Z0Y A;  1V2X A;  4L69 A;  4FMW A;  1VH0 A;  4YQD A;  4YQ0 A;  1UAM A;  4YPZ A;  4J3C A;  5JVG S;  3BBD A; 
#chains in the Genus database with same CATH homology
 3N4K A;  4YQ4 A;  3GYQ A;  2EGV A;  2QMM A;  3L8U A;  5CO4 A;  1Z85 A;  4JWJ A;  3KNU A;  4PZK A;  1VHY A;  3QUV A;  4JWG A;  4YQO A;  3OII A;  4CND A;  1ZJR A;  1UAK A;  4YQR A;  4E8B A;  3KTY A;  3KW2 A;  1GZ0 A;  3NK7 A;  3E5Y A;  4X3M A;  5FAI A;  1NXZ A;  4YVK A;  4X3L A;  3IC6 A;  4YPX A;  4JAK A;  5GMC A;  4YQ6 A;  1MXI A;  1K3R A;  4RG1 A;  4YQQ A;  1OY5 A;  1J85 A;  4YVI A;  2V3J A;  4YVG A;  4YPW A;  4YQL A;  1P9P A;  3ONP A;  4YQP A;  4YQC A;  4MCD A;  4IG6 A;  3AXZ A;  4H3Z A;  1X7O A;  4YQ5 A;  4KDZ A;  4YQ7 A;  3AIA A;  2NWA A;  1UAJ A;  4YQG A;  4FAK A;  3BBH A;  4JWF A;  4YQ2 A;  4YQS A;  4YQT A;  3N4J A;  4JAL A;  3OIN A;  4CNF A;  3BBE A;  1X7P A;  3ILK A;  2V3K A;  5GMB A;  4YQ8 A;  4YQI A;  3AI9 X;  4YPY A;  4YQA A;  1IPA A;  3NK6 A;  4YQ9 A;  4JWH A;  5D9F A;  4MCC A;  4YQB A;  4MCB A;  4XBO A;  4YQN A;  4YQ3 A;  1O6D A;  3IEF A;  4H3Y A;  1VHK A;  4KGN A;  1NS5 A;  4YQJ A;  2EGW A;  2QWV A;  2I6D A;  3KY7 A;  4YVJ A;  2O3A A;  4YQK A;  4YVH A;  3OIJ A;  1TO0 A;  2HA8 A;  2CX8 A;  4CNE A;  5GM8 A;  4CNG A;  2YY8 A;  3O7B A;  3DCM X;  1UAL A;  4YQ1 A;  1V6Z A;  2Z0Y A;  1V2X A;  4L69 A;  1VH0 A;  4YQD A;  4YQ0 A;  1UAM A;  4YPZ A;  4J3C A;  4FMW A;  3BBD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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