5BQIA

Discovery of a potent and selective mpges-1 inhibitor for the treatment of pain
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
148
structure length
148
Chain Sequence
SLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors.
pubmed doi rcsb
molecule tags Isomerase/isomerase inhibitor
source organism Homo sapiens
molecule keywords Prostaglandin E synthase
total genus 66
structure length 148
sequence length 148
ec nomenclature ec 5.3.99.3: Prostaglandin-E synthase.
pdb deposition date 2015-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01124 MAPEG MAPEG family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.550 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Membrane associated eicosanoid/glutathione metabolism-like domain 5bqiA00
2H8AA 4NTAA 2UUIA 2Q7RA 3PCVA 5HV9A 4NTFA 4YL3A 5BQHA 4JRZA 4J7YA 4YL1A 5BQIA 2PNOA 4J7TA 4JCZA 4AL0A 4NTBA 3DWWA 5K0IA 4WABA 4BPMA 3HKKA 4YK5A 3B29A 3LEOA 2UUHA 4AL1A 5BQGA 4YL0A 4JC7A
chains in the Genus database with same CATH superfamily
3O55A 2BL2A 1Z7Qc 1CGOA 5B3IA 4XEVA 3ZWIA 1ORJA 1ZU4A 1T5OA 1JRAA 4RDAA 2XLVA 4IGGA 3ZQYA 5DS6A 3E9VA 4YT2A 2J9BA 3N24A 4MVRA 4JEBA 3AOUA 3UNGC 3NMJA 5AC5A 1T01A 2AWCA 3NKDA 5K0IA 1HMOA 1MMAA 2PBEA 3QW1A 4C7OA 2XLEA 2Y3HA 3JSZA 4OD4A 2ZD9A 3EG9B 4OD5A 4QI0A 1JAFA 4U5GA 4ANJA 4OIRF 1FTSA 2Z15A 5L3VA 4CS7A 3MLGA 1OW6A 3R2PA 2H7VC 3DMDA 3DM5A 4I1OB 3AJMA 3LLKA 5T3WA 2G3VA 3VF0A 3TD7A 2B0HA 4CSAC 2H8AA 4P6IC 2Y3DA 3X2QC 2NUTA 3UGOA 1VB5A 4YJWA 4CDVA 1Q0FA 1MMNA 1OCZC 3AG2C 1Y6DA 3AGUA 3IQ6A 5COGA 2WVQA 5CIVA 1YA9A 3G4ZA 4JIOA 5L0IA 2D4UA 1D1AA 3US6A 5KYYA 4PFOA 1DOWA 1LE2A 5JUAA 2A6HF 2XRHA 3S27A 5BQIA 1FMVA 2KW3C 4DBQA 2DB4A 3C8GA 4NTBA 4PK4A 1A0BA 1EA8A 1I5NA 1NSGB 3K66A 5E33A 3T6BA 4CDAA 4CS8C 4E0IA 4YT4A 4DRJB 2C04A 3FMSA 2MWQA 3U9JA 2HS5A 2NUPB 4DRIB 3GORA 2HV7A 2R25A 3MX3A 3QW0A 1L3PA 3U9MA 3U2LA 3QTHA 2MHRA 4MW3A 2CNWA 2J0XA 3C8GD 3EH1A 3JYHA 1QQ3A 1O3UA 3X1OA 1HE9A 1T9KA 4JTAB 1KNYA 2YWAA 3W2VA 1LKXA 2HSQA 1TFOB 3V5XA 3C18A 5L0DA 3JYYA 3L0IA 2FGYA 2XL8A 3CZ6A 2YVKA 2XL6A 2Q3TA 2Y3BA 2Q9AA 3EGDA 3LUTB 3SEOA 2A6EF 5COFA 2J46A 3S28A 2JD3A 3T4RA 4E0HA 2B0JA 5A6KA 3U5SA 1Z3IX 5E3AA 2VB6A 2PP4A 2VCCA 4A4AA 3AQBA 3GEHA 4MVOA 4BPMA 1OCOC 1YLMA 1Z6AA 3B0PA 2QNLA 4QI2A 2F22A 1T6UA 2R03A 1VOMA 2X0CA 1V54C 2EPMX 4GQHA 1QSPA 2OEXA 2W4MA 4JURI 2H7BA 3RW0A 4HE8D 3H2UA 2IM8A 1NZEA 4HFFB 5L0JA 4I3MA 4DOZA 5COMA 1ZW3A 2R9RB 1K40A 2ASRA 4GEHA 2J8WA 2Q00A 2XL4A 3F46A 3U0CA 1Z23A 3M15A 3ZSUA 3NDBB 5L0FA 3RIPA 3GODA 4Z9IA 2HZ8A 3FDQA 1JMWA 1FFTC 3JTLO 1AEPA 4U5DE 1MMDA 2OCCC 4EBJA 5A69A 2PX3A 2YLDA 4R32A 1YAUO 2OJQA 1FR0A 1O87A 2NSGA 3MYIA 4I1MA 3TOLA 1S05A 4BJ6C 4OINF 1TWHA 2H7OA 4OIOF 3J06A 4YK5A 2QY9A 4C3BA 1ZZPA 3FXHA 3ABMC 2IXPA 1RJ9A 2WZLA 4CDYA 2G62A 2VCAA 4Z9JA 2P6VA 5EK0A 3DAFA 1TWGA 4U5HA 4X0RA 1FMWA 4MVMA 2UUIA 4MTGA 3M4CA 4U5FE 2XS8A 2J9VA 4PR9A 4BG0A 1BZ4A 3SXYA 1MQVA 1G8XA 3ECSA 1M2OA 3OWTA 3RVZA 1VLTA 2L9JA 1U0BB 4G7ZF 4NQFA 4O79A 3EHMA 2LIGA 4ULWA 4W8PA 3HNKA 5DQTA 2EINC 3B0VC 4IAQA 1OW7A 4Q4ZF 3N0TA 1Q0DA 2VC9A 1MNEA 3ABLC 3H65A 1K05A 5KYWA 4MQ9F 2KK1A 3VAYA 3IQ5A 3CQZA 5KYUB 2WB7A 3U3BA 3M4BA 3RQGA 2HFIA 3AQCA 3VYWA 4GYTA 3LS1A 3IHUA 1SR2A 2J7PD 1OCCC 5AC4A 5F5FA 1UG7A 1ZHYA 2YKZA 4NTAA 1HW2A 1OKKD 1YVIA 3FAPB 4IRUA 1LE4A 1UFBA 4ONSA 3DE9A 2CDQA 4N4WA 5HV9A 2XM0A 5JSLA 3L1MA 5BQHA 2FFHA 1LPEA 3U3FA 5FZTA 2AU5A 1HMDA 1C02A 4JJGA 2NPUA 2A69F 4PJLA 1OR3A 1QLEC 3T9OA 1V55C 1GGQA 2CW0F 4L6RA 2QLAA 4YWQA 1O5HA 2IOQA 5L0CA 3GWNA 1VYKA 3EHNA 1D0YA 4Q7CA 3RKOF 2XSEA 3JRTA 3V7OA 4UDVA 1GS9A 2L6GA 1L7CA 2LCHA 2GWWA 3HNIA 4JC7A 2GDCA 2I15A 4WJ0A 1VTMP 3ZVRA 4K7BA 2RSEB 4JJFA 4DBRA 1RCPA 1T6IA 2PF4E 5L3QA 1I4ZA 2AVKA 4DVYP 3ZTMA 3JRMO 4H54A 3GM3A 4JRZA 2RD9A 3DI5A 2OEVA 1OXBA 1ST6A 4U5BE 5JT4A 1E83A 4MVSA 1QZXA 2IBFA 2KNHA 2PFDA 3KL4A 3KYIA 5T3TA 5KYXA 5F5HA 4J32B 2WZFA 2XXAA 3WAQA 4DVZA 1OQCA 1BBHA 3DM9B 3MBGA 3I5PA 2EIJC 1PCXA 1F1MA 4AE4A 2YRFA 4C7OB 3AG4C 3A11A 3NKEA 2QE9A 4CIHA 1FAPB 3RQFA 1AVOB 3K33A 1RKCA 3ABKC 4IWBA 3VM6A 4FAPB 5IY5C 2C03A 3B29A 3LEOA 4W8KA 1FFHA 3SXMA 1U6HA 2ICWG 3HLZA 4KC9A 2MYSA 4E7SA 1CGME 4FESA 2GAQA 2WL8A 3C63A 2XLHA 2EILC 1GQAA 2NUTB 4O6YA 5D91A 1E2XA 4MTFA 3EFOA 3K1HA 3W4YA 4NTFA 1NFNA 3C7JA 2J9UA 2J9WA 1ZU5A 2ETSA 2OQMA 3NMIA 1A7EA 1TKNA 3UGPA 1M2VA 1RXQA 1SF8A 1VMAA 2HMZA 4G78A 5DVWA 5KYYB 3TQOA 2OG2A 4PACA 4OIPF 2HKVA 3DE8A 2ZPAA 2EIKC 2EIMC 1HE1A 2LK4A 2W45A 3O6XA 3VRCA 2YL3A 2I8BA 3BRJA 3C8GB 4AE4B 1YA7O 3EPVA 5BUOA 3AG1C 4EUKB 3FOOA 4U9EA 1J8YF 3O39A 4YT8A 4ZLDA 2J45A 1KU2A 1QPUA 2NSFA 2Y69C 3JZ0A 3EH2A 5CI9A 4E18A 4O6NA 2UUHA 2R7WA 4LDRA 5BQGA 2HV6A 3DJNB 3HNJA 4HEAJ 4M63A 4BEJA 4XTKA 4LLEA 4JTCB 2Q7RA 4AK9A 3U8PA 1EI7A 3PDMP 4U9DA 1ORYA 2LFFA 3L8JA 3NG1A 2L6FA 3Q6MA 3SZRA 2BE5F 4J7YA 5AGFA 3EGDB 3CSKA 1LS1A 1APCA 3V5ZA 1WN0A 2JX0A 2O9XA 1OW8A 5GPGB 2A68F 3ASNC 3NMKA 2ZXRA 256BA 1A41A 3DZAA 3KKBA 3SNHA 2XLWA 2WVOA 3PHF2 3T6GB 5DS5A 1SMYF 1LI7A 1H6GA 3E70C 2ZXOA 1DOVA 2XLDA 3JCUQ 5EGYA 1PV3A 4HFKB 4NC3A 5B3SC 1D1BA 4LERA 4XLNF 2VH3A 1FNTc 3EGXA 1TWCA 3IQCA 4MVUA 4K0DA 3UMIA 1QVXA 3GM1A 1MMGA 1OXKA 1YZAA 3SP1A 3TULA 1R4TA 3V5YA 3B0UX 2A0BA 3NRHA 4EBKA 2YHSA 2VCBA 3SXZA 3HJCA 3IPMO 4MS2A 1E86A 1AUEA 3TK0A 1LVKA 4Z9HA 2YEVA 4B6IA 3ZQVA 4J7TA 4JCZA 1TR2A 2R02A 3DWWA 3OEOA 4H4KC 5B1BC 1G5ZA 2P7VA 4ZLCA 5FCLA 2QUPA 2P1AA 2ZXWC 3GANA 5DS4A 2J7PA 1RKEA 1PD0A 4XLPF 2YL0A 1SZIA 3FAJA 1OKKA 1MNDA 4N6HA 4U5CE 5E2QA 1XZQA 1LM3B 4BJ5A 1YDIA 4JZAA 4WGZA 3T6JA 1BR1A 2DYRC 1RJ9B 2ZXPA 4C3DA 5T1DB 4IARA 2P0NA 4XWJA 5JS5A 3UMHA 3OA1A 1H9GA 4C3EA 1LS4A 2LD6A 3ATPA 1B68A 2Q4FA 4IJJA 2R7TA 3UMKA 1HY5A 4JW1A 4KI2A 2CGEA 2HJ3A 3Q7LA 3RVYA 2YL1A 3A9CA 3W8HA 2YLGA 3DD7A 4BEMJ 1BR2A 1M6TA 2HUJA 1V4AA 1T6QA 2PNOA 4PFPA 4IB4A 1YJGA 1YZCA 1V74B 3L34A 2XM4A 5JVEA 4BJ1A 4G7OF 3EG9A 3C8ZA 3I4UA 1LIHA 4J30B 4DRHB 5KYWB 5E3CA 1GM5A 2FAPB 3LNRA 3K1IA 3DAGA 1HW1A 5A6JA 1ZVZA 1Q0GA 4CJOA 1WGWA 2OKUA 3SYNA 3GEIA 4IAOA 3BEHA 4DXWA 1KTMA 3TJ5A 2JPUA 1E84A 4ULVA 1VYIA 3KH2A 4D4NA 4MVQA 1NU7D 1ZYRF 3CAXA 4XPYA 5D92A 4ER9A 1WASA 1R5ID 2KJGA 2EPLX 1SYQA 4FWVA 3W8IA 1ZHTA 1EKYA 3RH3A 2OOCA 3QZCA 4EKWA 3S0XA 3POVA 3GEEA 1D1CA 3NYLA 2R7VA 4XPWA 2KGOA 4MVZA 3WG7C 3EQLF 1YYXA 4KNWA 2EPKX 4EBBA 2KSFA 3G50A 3I5QA 4LLCA 4O7GA 1A7VA 4XEKA 1JPNA 2NUPA 3S90A 4G0HA 1S7ZA 2AP3A 2J0WA 2DYSC 1H7IA 4N6CA 4D4XA 4CJGA 1XZPA 3LJBA 4YN0B 2V26A 1BDJB 3MFNA 2XLMA 4XEFA 4A2NB 4YL0A 3FOPA 5CI8A 3U2MA 1RMVA 1TWAA 2BC5A 3DXJF 3ZIBA 3Q6NA 2R7QA 1Q0MA 1IW7F 3K6BA 2OJED 2LFDA 1CPRA 2Y39A 2KQ9A 1YYJA 2OU6A 3N2ZB 1H9TA 2WZGA 2XLOA 4CSAA 3HTKC 4PJJA 1NFOA 2EPNA 2R05A 1BR4A 3ZDLA 5A6AA 4NY3A 5DLJA 3H2VA 4JVSA 5KYXB 4PJMA 3NYMA 3PMRA 3RYLA 4CS9C 2XXAB 2M64A 2L7AA 3FVYA 3U8VA 1D0ZA 4MTOA 3KYJA 4RD9A 2LQGA 1E85A 4WABA 2GA0A 3IEEA 3WHNA 4CS9A 2L6HA 1Q0KA 4U5EE 3S9OA 4CS8A 2R7UA 4PJNA 2KC3A 1WOLA 2R7SA 1C17M 4AX2A 2VASA 4OIQF 3M79A 3DJUB 5F28E 1LI5A 1ORSC 3KMIA 2A1DD 3FHDA 1U89A 3AGTA 2CNWD 2YZSA 3TOMA 5HSWA 4E17A 2DI3A 5KYNA 3EFOB 1TQGA 3IQTA 2X51A 3LAYA 4JE9A 3EZIA 3ASOC 4CIPA 4BJTA 2IXMA 1JPJA 4EWCA 1M2VB 2XS1A 1N1CA 3C62A 3HNLA 5L0HA 2R7RA 3JSEO 1NBBA 5JP7A 4N06A 5JLIA 1J8MF 3LEVA 2KYHA 3ZG1A 4DJ9A 4JEAA 3ZC4A 3RQEA 3R7CA 3RF3A 1G4US 5JRAA 4O6MA 3RFYA 2L81A 2LSEA 3G4XA 4YT5A 3Q7GA 4JCHA 2G3KA 2IXOA 4AL1A 1WWPA 1G4WR 3K7DA 1CPQA 3DKAA 4LACB 5A6BA 1VK5A 1XWJA 3S29A 2YQYA 1M56C 4NCQA 2P61A 1QKRA 2A0UA 2LP4A 3PCVA 3LNMB 3EJNA 4JTDB 2CCYA 5L0GA 1OR2A 1TFKB 2PX0A 4FX5A 5A6BD 4YL1A 3F47A 1M57C 3GWLA 1ZHZA 1ZHXA 2AWYA 4MW8A 4LDQA 1Y4CA 4JKVA 1PD1A 4P9TA 2W4BA 2YL7A 4I44A 2EPOA 1A7DA 1Z5ZA 3ZTZA 4BJ5C 4RBNA 2HJMA 3LS0A 3LLIA 4Q5SF 2V3CC 5EHHA 4G7HF 4K1OA 5KYUA 1WTYA 2HMQA 3HKKA 2D5RB 2CYDA 4KBLA 3LESA 4XQ1A 5TJ5E 3M1CB 3W2WA 1NLXA 3QVZA 3WODF 4CX9A 2QTVA 4KNVA 1WATA 3EGXB 1CGNA 3UR3C 4BJ6A 4CBEA 4EIYA 3L8IA 1NG1A 1VLSA 4EHPA 1ZW2A 3GM2A 3CEXA 2GFHA 1JOGA 4XPXA 4QDLA 4YL3A 2DGJA 3B71A 2W9YA 3ITFA 2WVNA 2M4EA 2IXNA 2YLIA 4MNDA 3NYJA 2TMVP 2NG1A 1K04A 3QVYA 3TJ6A 3JT1A 1C03A 4WGYA 1EQ1A 3KPHA 4AL0A 1IZMA 3K1IC 3SXKA 3S84A 1Z63A 2Q9BA 4LDKA 5B1AC 2HSBA 2R7XA 1NU9C 1ZHWA 1JR8A 3EZHA 4P9FA 1RKEB 2E87A 1YARO 1W2WA 1OCRC 2R7OA 2IYLD 3B9QA 3O10A 3QMKA 1I4YA 5DQZA 4F4BA 4E7ZA 1D0XA 3AG3C 2Q9CA 2Y3GA 3MYFA
chains in the Genus database with same CATH topology
2H8AA 4NTAA 2UUIA 2Q7RA 3PCVA 5HV9A 4NTFA 4YL3A 5BQHA 4JRZA 4J7YA 4YL1A 5BQIA 2PNOA 4J7TA 4JCZA 4AL0A 4NTBA 3DWWA 5K0IA 4WABA 4BPMA 3HKKA 4YK5A 3B29A 3LEOA 2UUHA 4AL1A 5BQGA 4YL0A 4JC7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H8A A;  4NTA A;  2UUI A;  2Q7R A;  3PCV A;  5HV9 A;  4NTF A;  4YL3 A;  5BQH A;  4JRZ A;  4J7Y A;  4YL1 A;  5BQI A;  2PNO A;  4J7T A;  4JCZ A;  4AL0 A;  4NTB A;  3DWW A;  5K0I A;  4WAB A;  4BPM A;  3HKK A;  4YK5 A;  3B29 A;  3LEO A;  2UUH A;  4AL1 A;  5BQG A;  4YL0 A;  4JC7 A; 
#chains in the Genus database with same CATH topology
 3O55 A;  2BL2 A;  1Z7Q c;  1CGO A;  5B3I A;  4XEV A;  3ZWI A;  1ORJ A;  1ZU4 A;  1T5O A;  1JRA A;  4RDA A;  2XLV A;  4IGG A;  3ZQY A;  5DS6 A;  3E9V A;  4YT2 A;  2J9B A;  3N24 A;  4MVR A;  4JEB A;  3AOU A;  3UNG C;  3NMJ A;  5AC5 A;  1T01 A;  2AWC A;  3NKD A;  5K0I A;  1HMO A;  1MMA A;  2PBE A;  3QW1 A;  4C7O A;  2XLE A;  2Y3H A;  3JSZ A;  4OD4 A;  2ZD9 A;  3EG9 B;  4OD5 A;  4QI0 A;  1JAF A;  4U5G A;  4ANJ A;  4OIR F;  1FTS A;  2Z15 A;  5L3V A;  4CS7 A;  3MLG A;  1OW6 A;  3R2P A;  2H7V C;  3DMD A;  3DM5 A;  4I1O B;  3AJM A;  3LLK A;  5T3W A;  2G3V A;  3VF0 A;  3TD7 A;  2B0H A;  4CSA C;  2H8A A;  4P6I C;  2Y3D A;  3X2Q C;  2NUT A;  3UGO A;  1VB5 A;  4YJW A;  4CDV A;  1Q0F A;  1MMN A;  1OCZ C;  3AG2 C;  1Y6D A;  3AGU A;  3IQ6 A;  5COG A;  2WVQ A;  5CIV A;  1YA9 A;  3G4Z A;  4JIO A;  5L0I A;  2D4U A;  1D1A A;  3US6 A;  5KYY A;  4PFO A;  1DOW A;  1LE2 A;  5JUA A;  2A6H F;  2XRH A;  3S27 A;  5BQI A;  1FMV A;  2KW3 C;  4DBQ A;  2DB4 A;  3C8G A;  4NTB A;  4PK4 A;  1A0B A;  1EA8 A;  1I5N A;  1NSG B;  3K66 A;  5E33 A;  3T6B A;  4CDA A;  4CS8 C;  4E0I A;  4YT4 A;  4DRJ B;  2C04 A;  3FMS A;  2MWQ A;  3U9J A;  2HS5 A;  2NUP B;  4DRI B;  3GOR A;  2HV7 A;  2R25 A;  3MX3 A;  3QW0 A;  1L3P A;  3U9M A;  3U2L A;  3QTH A;  2MHR A;  4MW3 A;  2CNW A;  2J0X A;  3C8G D;  3EH1 A;  3JYH A;  1QQ3 A;  1O3U A;  3X1O A;  1HE9 A;  1T9K A;  4JTA B;  1KNY A;  2YWA A;  3W2V A;  1LKX A;  2HSQ A;  1TFO B;  3V5X A;  3C18 A;  5L0D A;  3JYY A;  3L0I A;  2FGY A;  2XL8 A;  3CZ6 A;  2YVK A;  2XL6 A;  2Q3T A;  2Y3B A;  2Q9A A;  3EGD A;  3LUT B;  3SEO A;  2A6E F;  5COF A;  2J46 A;  3S28 A;  2JD3 A;  3T4R A;  4E0H A;  2B0J A;  5A6K A;  3U5S A;  1Z3I X;  5E3A A;  2VB6 A;  2PP4 A;  2VCC A;  4A4A A;  3AQB A;  3GEH A;  4MVO A;  4BPM A;  1OCO C;  1YLM A;  1Z6A A;  3B0P A;  2QNL A;  4QI2 A;  2F22 A;  1T6U A;  2R03 A;  1VOM A;  2X0C A;  1V54 C;  2EPM X;  4GQH A;  1QSP A;  2OEX A;  2W4M A;  4JUR I;  2H7B A;  3RW0 A;  4HE8 D;  3H2U A;  2IM8 A;  1NZE A;  4HFF B;  5L0J A;  4I3M A;  4DOZ A;  5COM A;  1ZW3 A;  2R9R B;  1K40 A;  2ASR A;  4GEH A;  2J8W A;  2Q00 A;  2XL4 A;  3F46 A;  3U0C A;  1Z23 A;  3M15 A;  3ZSU A;  3NDB B;  5L0F A;  3RIP A;  3GOD A;  4Z9I A;  2HZ8 A;  3FDQ A;  1JMW A;  1FFT C;  3JTL O;  1AEP A;  4U5D E;  1MMD A;  2OCC C;  4EBJ A;  5A69 A;  2PX3 A;  2YLD A;  4R32 A;  1YAU O;  2OJQ A;  1FR0 A;  1O87 A;  2NSG A;  3MYI A;  4I1M A;  3TOL A;  1S05 A;  4BJ6 C;  4OIN F;  1TWH A;  2H7O A;  4OIO F;  3J06 A;  4YK5 A;  2QY9 A;  4C3B A;  1ZZP A;  3FXH A;  3ABM C;  2IXP A;  1RJ9 A;  2WZL A;  4CDY A;  2G62 A;  2VCA A;  4Z9J A;  2P6V A;  5EK0 A;  3DAF A;  1TWG A;  4U5H A;  4X0R A;  1FMW A;  4MVM A;  2UUI A;  4MTG A;  3M4C A;  4U5F E;  2XS8 A;  2J9V A;  4PR9 A;  4BG0 A;  1BZ4 A;  3SXY A;  1MQV A;  1G8X A;  3ECS A;  1M2O A;  3OWT A;  3RVZ A;  1VLT A;  2L9J A;  1U0B B;  4G7Z F;  4NQF A;  4O79 A;  3EHM A;  2LIG A;  4ULW A;  4W8P A;  3HNK A;  5DQT A;  2EIN C;  3B0V C;  4IAQ A;  1OW7 A;  4Q4Z F;  3N0T A;  1Q0D A;  2VC9 A;  1MNE A;  3ABL C;  3H65 A;  1K05 A;  5KYW A;  4MQ9 F;  2KK1 A;  3VAY A;  3IQ5 A;  3CQZ A;  5KYU B;  2WB7 A;  3U3B A;  3M4B A;  3RQG A;  2HFI A;  3AQC A;  3VYW A;  4GYT A;  3LS1 A;  3IHU A;  1SR2 A;  2J7P D;  1OCC C;  5AC4 A;  5F5F A;  1UG7 A;  1ZHY A;  2YKZ A;  4NTA A;  1HW2 A;  1OKK D;  1YVI A;  3FAP B;  4IRU A;  1LE4 A;  1UFB A;  4ONS A;  3DE9 A;  2CDQ A;  4N4W A;  5HV9 A;  2XM0 A;  5JSL A;  3L1M A;  5BQH A;  2FFH A;  1LPE A;  3U3F A;  5FZT A;  2AU5 A;  1HMD A;  1C02 A;  4JJG A;  2NPU A;  2A69 F;  4PJL A;  1OR3 A;  1QLE C;  3T9O A;  1V55 C;  1GGQ A;  2CW0 F;  4L6R A;  2QLA A;  4YWQ A;  1O5H A;  2IOQ A;  5L0C A;  3GWN A;  1VYK A;  3EHN A;  1D0Y A;  4Q7C A;  3RKO F;  2XSE A;  3JRT A;  3V7O A;  4UDV A;  1GS9 A;  2L6G A;  1L7C A;  2LCH A;  2GWW A;  3HNI A;  4JC7 A;  2GDC A;  2I15 A;  4WJ0 A;  1VTM P;  3ZVR A;  4K7B A;  2RSE B;  4JJF A;  4DBR A;  1RCP A;  1T6I A;  2PF4 E;  5L3Q A;  1I4Z A;  2AVK A;  4DVY P;  3ZTM A;  3JRM O;  4H54 A;  3GM3 A;  4JRZ A;  2RD9 A;  3DI5 A;  2OEV A;  1OXB A;  1ST6 A;  4U5B E;  5JT4 A;  1E83 A;  4MVS A;  1QZX A;  2IBF A;  2KNH A;  2PFD A;  3KL4 A;  3KYI A;  5T3T A;  5KYX A;  5F5H A;  4J32 B;  2WZF A;  2XXA A;  3WAQ A;  4DVZ A;  1OQC A;  1BBH A;  3DM9 B;  3MBG A;  3I5P A;  2EIJ C;  1PCX A;  1F1M A;  4AE4 A;  2YRF A;  4C7O B;  3AG4 C;  3A11 A;  3NKE A;  2QE9 A;  4CIH A;  1FAP B;  3RQF A;  1AVO B;  3K33 A;  1RKC A;  3ABK C;  4IWB A;  3VM6 A;  4FAP B;  5IY5 C;  2C03 A;  3B29 A;  3LEO A;  4W8K A;  1FFH A;  3SXM A;  1U6H A;  2ICW G;  3HLZ A;  4KC9 A;  2MYS A;  4E7S A;  1CGM E;  4FES A;  2GAQ A;  2WL8 A;  3C63 A;  2XLH A;  2EIL C;  1GQA A;  2NUT B;  4O6Y A;  5D91 A;  1E2X A;  4MTF A;  3EFO A;  3K1H A;  3W4Y A;  4NTF A;  1NFN A;  3C7J A;  2J9U A;  2J9W A;  1ZU5 A;  2ETS A;  2OQM A;  3NMI A;  1A7E A;  1TKN A;  3UGP A;  1M2V A;  1RXQ A;  1SF8 A;  1VMA A;  2HMZ A;  4G78 A;  5DVW A;  5KYY B;  3TQO A;  2OG2 A;  4PAC A;  4OIP F;  2HKV A;  3DE8 A;  2ZPA A;  2EIK C;  2EIM C;  1HE1 A;  2LK4 A;  2W45 A;  3O6X A;  3VRC A;  2YL3 A;  2I8B A;  3BRJ A;  3C8G B;  4AE4 B;  1YA7 O;  3EPV A;  5BUO A;  3AG1 C;  4EUK B;  3FOO A;  4U9E A;  1J8Y F;  3O39 A;  4YT8 A;  4ZLD A;  2J45 A;  1KU2 A;  1QPU A;  2NSF A;  2Y69 C;  3JZ0 A;  3EH2 A;  5CI9 A;  4E18 A;  4O6N A;  2UUH A;  2R7W A;  4LDR A;  5BQG A;  2HV6 A;  3DJN B;  3HNJ A;  4HEA J;  4M63 A;  4BEJ A;  4XTK A;  4LLE A;  4JTC B;  2Q7R A;  4AK9 A;  3U8P A;  1EI7 A;  3PDM P;  4U9D A;  1ORY A;  2LFF A;  3L8J A;  3NG1 A;  2L6F A;  3Q6M A;  3SZR A;  2BE5 F;  4J7Y A;  5AGF A;  3EGD B;  3CSK A;  1LS1 A;  1APC A;  3V5Z A;  1WN0 A;  2JX0 A;  2O9X A;  1OW8 A;  5GPG B;  2A68 F;  3ASN C;  3NMK A;  2ZXR A;  256B A;  1A41 A;  3DZA A;  3KKB A;  3SNH A;  2XLW A;  2WVO A;  3PHF 2;  3T6G B;  5DS5 A;  1SMY F;  1LI7 A;  1H6G A;  3E70 C;  2ZXO A;  1DOV A;  2XLD A;  3JCU Q;  5EGY A;  1PV3 A;  4HFK B;  4NC3 A;  5B3S C;  1D1B A;  4LER A;  4XLN F;  2VH3 A;  1FNT c;  3EGX A;  1TWC A;  3IQC A;  4MVU A;  4K0D A;  3UMI A;  1QVX A;  3GM1 A;  1MMG A;  1OXK A;  1YZA A;  3SP1 A;  3TUL A;  1R4T A;  3V5Y A;  3B0U X;  2A0B A;  3NRH A;  4EBK A;  2YHS A;  2VCB A;  3SXZ A;  3HJC A;  3IPM O;  4MS2 A;  1E86 A;  1AUE A;  3TK0 A;  1LVK A;  4Z9H A;  2YEV A;  4B6I A;  3ZQV A;  4J7T A;  4JCZ A;  1TR2 A;  2R02 A;  3DWW A;  3OEO A;  4H4K C;  5B1B C;  1G5Z A;  2P7V A;  4ZLC A;  5FCL A;  2QUP A;  2P1A A;  2ZXW C;  3GAN A;  5DS4 A;  2J7P A;  1RKE A;  1PD0 A;  4XLP F;  2YL0 A;  1SZI A;  3FAJ A;  1OKK A;  1MND A;  4N6H A;  4U5C E;  5E2Q A;  1XZQ A;  1LM3 B;  4BJ5 A;  1YDI A;  4JZA A;  4WGZ A;  3T6J A;  1BR1 A;  2DYR C;  1RJ9 B;  2ZXP A;  4C3D A;  5T1D B;  4IAR A;  2P0N A;  4XWJ A;  5JS5 A;  3UMH A;  3OA1 A;  1H9G A;  4C3E A;  1LS4 A;  2LD6 A;  3ATP A;  1B68 A;  2Q4F A;  4IJJ A;  2R7T A;  3UMK A;  1HY5 A;  4JW1 A;  4KI2 A;  2CGE A;  2HJ3 A;  3Q7L A;  3RVY A;  2YL1 A;  3A9C A;  3W8H A;  2YLG A;  3DD7 A;  4BEM J;  1BR2 A;  1M6T A;  2HUJ A;  1V4A A;  1T6Q A;  2PNO A;  4PFP A;  4IB4 A;  1YJG A;  1YZC A;  1V74 B;  3L34 A;  2XM4 A;  5JVE A;  4BJ1 A;  4G7O F;  3EG9 A;  3C8Z A;  3I4U A;  1LIH A;  4J30 B;  4DRH B;  5KYW B;  5E3C A;  1GM5 A;  2FAP B;  3LNR A;  3K1I A;  3DAG A;  1HW1 A;  5A6J A;  1ZVZ A;  1Q0G A;  4CJO A;  1WGW A;  2OKU A;  3SYN A;  3GEI A;  4IAO A;  3BEH A;  4DXW A;  1KTM A;  3TJ5 A;  2JPU A;  1E84 A;  4ULV A;  1VYI A;  3KH2 A;  4D4N A;  4MVQ A;  1NU7 D;  1ZYR F;  3CAX A;  4XPY A;  5D92 A;  4ER9 A;  1WAS A;  1R5I D;  2KJG A;  2EPL X;  1SYQ A;  4FWV A;  3W8I A;  1ZHT A;  1EKY A;  3RH3 A;  2OOC A;  3QZC A;  4EKW A;  3S0X A;  3POV A;  3GEE A;  1D1C A;  3NYL A;  2R7V A;  4XPW A;  2KGO A;  4MVZ A;  3WG7 C;  3EQL F;  1YYX A;  4KNW A;  2EPK X;  4EBB A;  2KSF A;  3G50 A;  3I5Q A;  4LLC A;  4O7G A;  1A7V A;  4XEK A;  1JPN A;  2NUP A;  3S90 A;  4G0H A;  1S7Z A;  2AP3 A;  2J0W A;  2DYS C;  1H7I A;  4N6C A;  4D4X A;  4CJG A;  1XZP A;  3LJB A;  4YN0 B;  2V26 A;  1BDJ B;  3MFN A;  2XLM A;  4XEF A;  4A2N B;  4YL0 A;  3FOP A;  5CI8 A;  3U2M A;  1RMV A;  1TWA A;  2BC5 A;  3DXJ F;  3ZIB A;  3Q6N A;  2R7Q A;  1Q0M A;  1IW7 F;  3K6B A;  2OJE D;  2LFD A;  1CPR A;  2Y39 A;  2KQ9 A;  1YYJ A;  2OU6 A;  3N2Z B;  1H9T A;  2WZG A;  2XLO A;  4CSA A;  3HTK C;  4PJJ A;  1NFO A;  2EPN A;  2R05 A;  1BR4 A;  3ZDL A;  5A6A A;  4NY3 A;  5DLJ A;  3H2V A;  4JVS A;  5KYX B;  4PJM A;  3NYM A;  3PMR A;  3RYL A;  4CS9 C;  2XXA B;  2M64 A;  2L7A A;  3FVY A;  3U8V A;  1D0Z A;  4MTO A;  3KYJ A;  4RD9 A;  2LQG A;  1E85 A;  4WAB A;  2GA0 A;  3IEE A;  3WHN A;  4CS9 A;  2L6H A;  1Q0K A;  4U5E E;  3S9O A;  4CS8 A;  2R7U A;  4PJN A;  2KC3 A;  1WOL A;  2R7S A;  1C17 M;  4AX2 A;  2VAS A;  4OIQ F;  3M79 A;  3DJU B;  5F28 E;  1LI5 A;  1ORS C;  3KMI A;  2A1D D;  3FHD A;  1U89 A;  3AGT A;  2CNW D;  2YZS A;  3TOM A;  5HSW A;  4E17 A;  2DI3 A;  5KYN A;  3EFO B;  1TQG A;  3IQT A;  2X51 A;  3LAY A;  4JE9 A;  3EZI A;  3ASO C;  4CIP A;  4BJT A;  2IXM A;  1JPJ A;  4EWC A;  1M2V B;  2XS1 A;  1N1C A;  3C62 A;  3HNL A;  5L0H A;  2R7R A;  3JSE O;  1NBB A;  5JP7 A;  4N06 A;  5JLI A;  1J8M F;  3LEV A;  2KYH A;  3ZG1 A;  4DJ9 A;  4JEA A;  3ZC4 A;  3RQE A;  3R7C A;  3RF3 A;  1G4U S;  5JRA A;  4O6M A;  3RFY A;  2L81 A;  2LSE A;  3G4X A;  4YT5 A;  3Q7G A;  4JCH A;  2G3K A;  2IXO A;  4AL1 A;  1WWP A;  1G4W R;  3K7D A;  1CPQ A;  3DKA A;  4LAC B;  5A6B A;  1VK5 A;  1XWJ A;  3S29 A;  2YQY A;  1M56 C;  4NCQ A;  2P61 A;  1QKR A;  2A0U A;  2LP4 A;  3PCV A;  3LNM B;  3EJN A;  4JTD B;  2CCY A;  5L0G A;  1OR2 A;  1TFK B;  2PX0 A;  4FX5 A;  5A6B D;  4YL1 A;  3F47 A;  1M57 C;  3GWL A;  1ZHZ A;  1ZHX A;  2AWY A;  4MW8 A;  4LDQ A;  1Y4C A;  4JKV A;  1PD1 A;  4P9T A;  2W4B A;  2YL7 A;  4I44 A;  2EPO A;  1A7D A;  1Z5Z A;  3ZTZ A;  4BJ5 C;  4RBN A;  2HJM A;  3LS0 A;  3LLI A;  4Q5S F;  2V3C C;  5EHH A;  4G7H F;  4K1O A;  5KYU A;  1WTY A;  2HMQ A;  3HKK A;  2D5R B;  2CYD A;  4KBL A;  3LES A;  4XQ1 A;  5TJ5 E;  3M1C B;  3W2W A;  1NLX A;  3QVZ A;  3WOD F;  4CX9 A;  2QTV A;  4KNV A;  1WAT A;  3EGX B;  1CGN A;  3UR3 C;  4BJ6 A;  4CBE A;  4EIY A;  3L8I A;  1NG1 A;  1VLS A;  4EHP A;  1ZW2 A;  3GM2 A;  3CEX A;  2GFH A;  1JOG A;  4XPX A;  4QDL A;  4YL3 A;  2DGJ A;  3B71 A;  2W9Y A;  3ITF A;  2WVN A;  2M4E A;  2IXN A;  2YLI A;  4MND A;  3NYJ A;  2TMV P;  2NG1 A;  1K04 A;  3QVY A;  3TJ6 A;  3JT1 A;  1C03 A;  4WGY A;  1EQ1 A;  3KPH A;  4AL0 A;  1IZM A;  3K1I C;  3SXK A;  3S84 A;  1Z63 A;  2Q9B A;  4LDK A;  5B1A C;  2HSB A;  2R7X A;  1NU9 C;  1ZHW A;  1JR8 A;  3EZH A;  4P9F A;  1RKE B;  2E87 A;  1YAR O;  1W2W A;  1OCR C;  2R7O A;  2IYL D;  3B9Q A;  3O10 A;  3QMK A;  1I4Y A;  5DQZ A;  4F4B A;  4E7Z A;  1D0X A;  3AG3 C;  2Q9C A;  2Y3G A;  3MYF A; 
#chains in the Genus database with same CATH homology
 2H8A A;  4NTA A;  2UUI A;  2Q7R A;  3PCV A;  5HV9 A;  4NTF A;  4YL3 A;  5BQH A;  4JRZ A;  4J7Y A;  4YL1 A;  5BQI A;  2PNO A;  4J7T A;  4JCZ A;  4AL0 A;  4NTB A;  3DWW A;  5K0I A;  4WAB A;  4BPM A;  3HKK A;  4YK5 A;  3B29 A;  3LEO A;  2UUH A;  4AL1 A;  5BQG A;  4YL0 A;  4JC7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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