|
162
|
519
|
4q0dA |
Crystal structure of ts-dhfr from cryptosporidium hominis in complex with nadph, fdump, methotrexate and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-l-glutamic acid. |
|
84
|
313
|
4o7uA |
Etherocomplex of enteroccocus faecalis thymidylate synthase with 5-hydroxymethilene-6-hydrofolic acid and the phtalimidic inhibitor ss7 |
|
72
|
284
|
4o1uA |
Crystal structure of human thymidylate synthase mutant y202c |
|
87
|
288
|
4o1xA |
Crystal structure of human thymidylate synthase double mutant c195s-y202c |
|
92
|
282
|
4o1xD |
Crystal structure of human thymidylate synthase double mutant c195s-y202c |
|
83
|
264
|
4lrrA |
Ternary complex between e. coli thymidylate synthase, dump, and f9 |
|
158
|
563
|
4kyaA |
Crystal structure of non-classical ts inhibitor 3 in complex with toxoplasma gondii ts-dhfr |
|
79
|
286
|
4kpwA |
Crystal structure of his-tagged human thymidylate synthase r175a mutant |
|
143
|
608
|
4ky4A |
Crystal structure of non-classical ts inhibitor 2 in complex with toxoplasma gondii ts-dhfr |
|
158
|
519
|
4ky8A |
Crystal structure of ts-dhfr from cryptosporidium hominis in complex with nadph, methotrexate, fdump and 4-((2-amino-6-methyl-4-oxo-4,7-dihydro-3h-pyrrolo[2,3-d]pyrimidin-5-yl)thio)-2-chlorophenyl)-l-glutamic acid |
|
80
|
263
|
4iskA |
Crystal structure of e.coli thymidylate synthase with dump and the bgc 945 inhibitor |
|
67
|
286
|
4jefA |
Crystal structure of human thymidylate synthase y202a in inactive conformation. |
|
86
|
289
|
4iqqA |
Crystal structure of c.elegans thymidylate synthase in complex with dump and tomudex |
|
96
|
288
|
4iqbA |
High resolution crystal structure of c.elegans thymidylate synthase |
|
96
|
290
|
4irrA |
Crystal structure of c.elegans thymidylate synthase in complex with dump |
|
89
|
290
|
4iswA |
Crystal structure of phosphorylated c.elegans thymidylate synthase in complex with dump |
|
84
|
281
|
4h1iA |
Structure of human thymidylate synthase at low salt conditions |
|
73
|
285
|
4gyhA |
Structure of human thymidylate synthase at high salt conditions |
|
79
|
260
|
4h0rA |
Crystal structure of thymidylate synthase from corynebacterium glutamicum |
|
81
|
264
|
4h0uA |
Crystal structure of thymidylate synthase from corynebacterium glutamicum in complex with dump |
|
73
|
284
|
4g6wX |
Human thymidylate synthase m190k with bound 4-bromobenzene-1,2,3-triol |
|
79
|
263
|
4gevA |
E. coli thymidylate synthase y209w variant in complex with substrate and a cofactor analog |
|
75
|
284
|
4gd7A |
Wild-type human thymidylate synthase with bound purpurogallin |
|
76
|
284
|
4g2oX |
Human thymidylate synthase m190k with bound purpurogallin |
|
85
|
263
|
4fqsA |
Crystal structure of mycobacterium tuberculosis thya in complex with ump and pemetrexed |
|
84
|
283
|
4fgtA |
Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme. |
|
76
|
260
|
4fogA |
Crystal structure of mtb thya in complex with 5-fluoro-dump and 5-methyltetrahydrofolic acid |
|
83
|
261
|
4foaA |
Crystal structure of the mtb thya in complex with 5-fluoro-dump |
|
79
|
261
|
4foxA |
Crystal structure of mtb thya in complex with dump and raltitrexed |
|
173
|
608
|
3qg2A |
Plasmodium falciparum dhfr-ts qradruple mutant (n51i+c59r+s108n+i164l, v1/s) pyrimethamine complex |
|
58
|
219
|
3qfxA |
Trypanosoma brucei dihydrofolate reductase pyrimethamine complex |
|
177
|
608
|
3qgtA |
Crystal structure of wild-type pfdhfr-ts complexed with nadph, dump and pyrimethamine |
|
83
|
260
|
3qj7A |
Crystal structure of the mycobacterium tuberculosis thymidylate synthase (thya) bound to dump |
|
90
|
281
|
3ob7A |
Human thymidylate synthase r163k with cys 195 covalently modified by glutathione |
|
162
|
509
|
3nrrA |
Co-crystal structure of dihydrofolate reductase-thymidylate synthase from babesia bovis with dump, raltitrexed and nadp |
|
71
|
285
|
3n5eB |
Crystal structure of human thymidylate synthase bound to a peptide inhibitor |
|
75
|
285
|
3n5gA |
Crystal structure of histidine-tagged human thymidylate synthase |
|
70
|
285
|
3n5eA |
Crystal structure of human thymidylate synthase bound to a peptide inhibitor |
|
152
|
514
|
3kjsA |
Crystal structure of t. cruzi dhfr-ts with 3 high affinity dhfr inhibitors: dq1 inhibitor complex |
|
76
|
279
|
3kgbA |
Crystal structure of thymidylate synthase 1/2 from encephalitozoon cuniculi at 2.2 a resolution |
|
159
|
507
|
3kjrA |
Crystal structure of dihydrofolate reductase/thymidylate synthase from babesia bovis determined using slipchip based microfluidics |
|
177
|
606
|
3jsuA |
Quadruple mutant(n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase(pfdhfr-ts) complexed with qn254, nadph, and dump |
|
163
|
508
|
3k2hA |
Co-crystal structure of dihydrofolate reductase/thymidylate synthase from babesia bovis with dump, pemetrexed and nadp |
|
160
|
514
|
3invA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with nadph, dump and c-448 antifolate |
|
80
|
251
|
3ix6A |
Crystal structure of thymidylate synthase thya from brucella melitensis |
|
97
|
311
|
3ik1A |
Lactobacillus casei thymidylate synthase in ternary complex with dump and the phtalimidic derivative 20c |
|
156
|
518
|
3iroA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with nadph and q-8 antifolate |
|
161
|
520
|
3irmA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with cycloguanil |
|
152
|
516
|
3irnA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with nadph and cycloguanil |
|
96
|
312
|
3ik0A |
Lactobacillus casei thymidylate synthase in ternary complex with dump and the phtalimidic derivative 7c1 |
