1F3HA

X-ray crystal structure of the human anti-apoptotic protein survivin
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
136
structure length
136
Chain Sequence
TLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDMAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords SURVIVIN
total genus 42
structure length 136
sequence length 136
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 1f3hA00
4KJUA 3M0AD 3F7IA 1OXNA 3SIPE 3UEGA 5C83A 4J3YA 1C9QA 2RAWA 3UW5A 4LGEA 3CLXA 4KMNA 1TFTA 3UIGA 1JD5A 3UEIA 2I3HA 3M0DD 3UEEA 4J46A 4KJVA 1M4MA 2JK7A 3HL5A 1OXQA 5C7AA 3UEDA 1SDZA 3UECA 3UW4A 2OPYA 2QRAA 3MUPA 4WVSA 4J48A 2I3IA 3GTAA 3UIKA 3SIQA 4J45A 1TFQA 4A0IA 3EYLA 4WVUA 4LGUA 1Q4QA 3OZ1A 2UVLA 4MU7A 2POPB 1XB0A 2VSLA 4HY5A 2POIA 3GT9A 4EB9A 4A0NA 1I3OE 1E31A 4J47A 4EC4A 1G3FA 1TW6A 3F7HA 3D9UA 4J44A 1OY7A 3UEFA 1NW9A 3D9TA 2RAXA 5C7BA 1XOXA 2VM5A 3UEHA 4HY4A 4HY0A 1JD6A 3CM7A 3M1DA 3UIIA 5C7DA 4A0JA 5C3HA 1F3HA 3G76A 3T6PA 3UIJA 4WVTA 3UIHA 4MTZA 4KMPA 5C3KA 3F7GA 5C84A 5C7CA 4OXCA 2OPZA 4MTIA 1G73C 1QBHA 3CM2A 5C0KA 1F9XA 1SE0A 1XB1A 5C0LA 2QFAA 1JD4A
chains in the Genus database with same CATH superfamily
4KJUA 3M0AD 3F7IA 1OXNA 3SIPE 3UEGA 5C83A 4J3YA 1C9QA 2RAWA 3UW5A 4LGEA 3CLXA 4KMNA 1TFTA 3UIGA 1JD5A 3UEIA 2I3HA 3M0DD 3UEEA 4J46A 4KJVA 1M4MA 2JK7A 3HL5A 1OXQA 5C7AA 3UEDA 1SDZA 3UECA 3UW4A 2OPYA 2QRAA 3MUPA 4WVSA 4J48A 2I3IA 3GTAA 3UIKA 3SIQA 4J45A 1TFQA 4A0IA 3EYLA 4WVUA 4LGUA 1Q4QA 3OZ1A 2UVLA 4MU7A 2POPB 1XB0A 2VSLA 4HY5A 2POIA 3GT9A 4EB9A 4A0NA 1I3OE 1E31A 4J47A 4EC4A 1G3FA 1TW6A 3F7HA 3D9UA 4J44A 1OY7A 3UEFA 1NW9A 3D9TA 2RAXA 5C7BA 1XOXA 2VM5A 3UEHA 4HY4A 4HY0A 1JD6A 3CM7A 3M1DA 3UIIA 5C7DA 4A0JA 5C3HA 1F3HA 3G76A 3T6PA 3UIJA 4WVTA 3UIHA 4MTZA 4KMPA 5C3KA 3F7GA 5C84A 5C7CA 4OXCA 2OPZA 4MTIA 1G73C 1QBHA 3CM2A 5C0KA 1F9XA 1SE0A 1XB1A 5C0LA 2QFAA 1JD4A
chains in the Genus database with same CATH topology
4KJUA 3M0AD 3F7IA 1OXNA 3SIPE 3UEGA 5C83A 4J3YA 1C9QA 2RAWA 3UW5A 4LGEA 3CLXA 4KMNA 1TFTA 3UIGA 1JD5A 3UEIA 2I3HA 3M0DD 3UEEA 4J46A 4KJVA 1M4MA 2JK7A 3HL5A 1OXQA 5C7AA 3UEDA 1SDZA 3UECA 3UW4A 2OPYA 2QRAA 3MUPA 4WVSA 4J48A 2I3IA 3GTAA 3UIKA 3SIQA 4J45A 1TFQA 4A0IA 3EYLA 4WVUA 4LGUA 1Q4QA 3OZ1A 2UVLA 4MU7A 2POPB 1XB0A 2VSLA 4HY5A 2POIA 3GT9A 4EB9A 4A0NA 1I3OE 1E31A 4J47A 4EC4A 1G3FA 1TW6A 3F7HA 3D9UA 4J44A 1OY7A 3UEFA 1NW9A 3D9TA 2RAXA 5C7BA 1XOXA 2VM5A 3UEHA 4HY4A 4HY0A 1JD6A 3CM7A 3M1DA 3UIIA 5C7DA 4A0JA 5C3HA 1F3HA 3G76A 3T6PA 3UIJA 4WVTA 3UIHA 4MTZA 4KMPA 5C3KA 3F7GA 5C84A 5C7CA 4OXCA 2OPZA 4MTIA 1G73C 1QBHA 3CM2A 5C0KA 1F9XA 1SE0A 1XB1A 5C0LA 2QFAA 1JD4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KJU A;  3M0A D;  3F7I A;  1OXN A;  3SIP E;  3UEG A;  5C83 A;  4J3Y A;  1C9Q A;  2RAW A;  3UW5 A;  4LGE A;  3CLX A;  4KMN A;  1TFT A;  3UIG A;  1JD5 A;  3UEI A;  2I3H A;  3M0D D;  3UEE A;  4J46 A;  4KJV A;  1M4M A;  2JK7 A;  3HL5 A;  1OXQ A;  5C7A A;  3UED A;  1SDZ A;  3UEC A;  3UW4 A;  2OPY A;  2QRA A;  3MUP A;  4WVS A;  4J48 A;  2I3I A;  3GTA A;  3UIK A;  3SIQ A;  4J45 A;  1TFQ A;  4A0I A;  3EYL A;  4WVU A;  4LGU A;  1Q4Q A;  3OZ1 A;  2UVL A;  4MU7 A;  2POP B;  1XB0 A;  2VSL A;  4HY5 A;  2POI A;  3GT9 A;  4EB9 A;  4A0N A;  1I3O E;  1E31 A;  4J47 A;  4EC4 A;  1G3F A;  1TW6 A;  3F7H A;  3D9U A;  4J44 A;  1OY7 A;  3UEF A;  1NW9 A;  3D9T A;  2RAX A;  5C7B A;  1XOX A;  2VM5 A;  3UEH A;  4HY4 A;  4HY0 A;  1JD6 A;  3CM7 A;  3M1D A;  3UII A;  5C7D A;  4A0J A;  5C3H A;  1F3H A;  3G76 A;  3T6P A;  3UIJ A;  4WVT A;  3UIH A;  4MTZ A;  4KMP A;  5C3K A;  3F7G A;  5C84 A;  5C7C A;  4OXC A;  2OPZ A;  4MTI A;  1G73 C;  1QBH A;  3CM2 A;  5C0K A;  1F9X A;  1SE0 A;  1XB1 A;  5C0L A;  2QFA A;  1JD4 A; 
#chains in the Genus database with same CATH topology
 4KJU A;  3M0A D;  3F7I A;  1OXN A;  3SIP E;  3UEG A;  5C83 A;  4J3Y A;  1C9Q A;  2RAW A;  3UW5 A;  4LGE A;  3CLX A;  4KMN A;  1TFT A;  3UIG A;  1JD5 A;  3UEI A;  2I3H A;  3M0D D;  3UEE A;  4J46 A;  4KJV A;  1M4M A;  2JK7 A;  3HL5 A;  1OXQ A;  5C7A A;  3UED A;  1SDZ A;  3UEC A;  3UW4 A;  2OPY A;  2QRA A;  3MUP A;  4WVS A;  4J48 A;  2I3I A;  3GTA A;  3UIK A;  3SIQ A;  4J45 A;  1TFQ A;  4A0I A;  3EYL A;  4WVU A;  4LGU A;  1Q4Q A;  3OZ1 A;  2UVL A;  4MU7 A;  2POP B;  1XB0 A;  2VSL A;  4HY5 A;  2POI A;  3GT9 A;  4EB9 A;  4A0N A;  1I3O E;  1E31 A;  4J47 A;  4EC4 A;  1G3F A;  1TW6 A;  3F7H A;  3D9U A;  4J44 A;  1OY7 A;  3UEF A;  1NW9 A;  3D9T A;  2RAX A;  5C7B A;  1XOX A;  2VM5 A;  3UEH A;  4HY4 A;  4HY0 A;  1JD6 A;  3CM7 A;  3M1D A;  3UII A;  5C7D A;  4A0J A;  5C3H A;  1F3H A;  3G76 A;  3T6P A;  3UIJ A;  4WVT A;  3UIH A;  4MTZ A;  4KMP A;  5C3K A;  3F7G A;  5C84 A;  5C7C A;  4OXC A;  2OPZ A;  4MTI A;  1G73 C;  1QBH A;  3CM2 A;  5C0K A;  1F9X A;  1SE0 A;  1XB1 A;  5C0L A;  2QFA A;  1JD4 A; 
#chains in the Genus database with same CATH homology
 4KJU A;  3M0A D;  3F7I A;  1OXN A;  3SIP E;  3UEG A;  5C83 A;  4J3Y A;  1C9Q A;  2RAW A;  3UW5 A;  4LGE A;  3CLX A;  4KMN A;  1TFT A;  3UIG A;  1JD5 A;  3UEI A;  2I3H A;  3M0D D;  3UEE A;  4J46 A;  4KJV A;  1M4M A;  2JK7 A;  3HL5 A;  1OXQ A;  5C7A A;  3UED A;  1SDZ A;  3UEC A;  3UW4 A;  2OPY A;  2QRA A;  3MUP A;  4WVS A;  4J48 A;  2I3I A;  3GTA A;  3UIK A;  3SIQ A;  4J45 A;  1TFQ A;  4A0I A;  3EYL A;  4WVU A;  4LGU A;  1Q4Q A;  3OZ1 A;  2UVL A;  4MU7 A;  2POP B;  1XB0 A;  2VSL A;  4HY5 A;  2POI A;  3GT9 A;  4EB9 A;  4A0N A;  1I3O E;  1E31 A;  4J47 A;  4EC4 A;  1G3F A;  1TW6 A;  3F7H A;  3D9U A;  4J44 A;  1OY7 A;  3UEF A;  1NW9 A;  3D9T A;  2RAX A;  5C7B A;  1XOX A;  2VM5 A;  3UEH A;  4HY4 A;  4HY0 A;  1JD6 A;  3CM7 A;  3M1D A;  3UII A;  5C7D A;  4A0J A;  5C3H A;  1F3H A;  3G76 A;  3T6P A;  3UIJ A;  4WVT A;  3UIH A;  4MTZ A;  4KMP A;  5C3K A;  3F7G A;  5C84 A;  5C7C A;  4OXC A;  2OPZ A;  4MTI A;  1G73 C;  1QBH A;  3CM2 A;  5C0K A;  1F9X A;  1SE0 A;  1XB1 A;  5C0L A;  2QFA A;  1JD4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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