1H2CA

Ebola virus matrix protein vp40 n-terminal domain in complex with rna (high-resolution vp40[55-194] variant).
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
124
structure length
124
Chain Sequence
VSSAFILEAMVNVISGPKVLMKQIPIWLPLGVADQKTYSFDSTTAAIMLASYTITHFGKATNPLVRVNRLGPGIPDHPLRLLRIGNQAFLQEFVLPPVQLPQYFTFDLTALKLITQPLPAATWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Matrix Protein Vp40 from Ebola Virus Octamerizes Into Pore-Like Structures with Specific RNA Binding Properties
pubmed doi rcsb
molecule keywords MATRIX PROTEIN VP40
molecule tags Virus/viral protein
source organism Ebola virus
total genus 22
structure length 124
sequence length 124
ec nomenclature
pdb deposition date 2002-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.20.20 Mainly Beta Distorted Sandwich Topoisomerase I; domain 3 Topoisomerase I; domain 3 1h2cA00
4LDMA 5B0VA 4LDBA 4LDDA 1H2DA 1ES6A 4LD8A 3TCQA 1H2CA
chains in the Genus database with same CATH superfamily
2O19A 1CY6A 2GAIA 4LDMA 4CHTA 1ECLA 3PWTA 1H2DA 4HI5A 3PX7A 1CY1A 1CY4A 4HIUA 3TCQA 2O5CA 1MW8X 4HITA 4LDDA 1I7DA 1CY7A 1CY0A 1CY2A 4D4TA 4RULA 5D5HA 4G1LA 4LDBA 4HIWA 2YKDA 4G1GA 4G1OA 4V23A 1ES6A 1MW9X 4HIYA 4CGYA 1D6MA 1H2CA 4HI6A 1CYYA 1CY9A 3F1JA 5B0VA 2O5EA 2O54A 4LP7A 4LD8A 2GAJA 1CY8A 2O59A 2VQPA
chains in the Genus database with same CATH topology
4LDMA 1H2DA 4HI5A 4HIUA 3TCQA 4HITA 4LDDA 4D4TA 4G1LA 4LDBA 4HIWA 2YKDA 4G1GA 4G1OA 4V23A 1ES6A 4HIYA 1H2CA 4HI6A 3F1JA 5B0VA 4LP7A 4LD8A 2VQPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LDM A;  5B0V A;  4LDB A;  4LDD A;  1H2D A;  1ES6 A;  4LD8 A;  3TCQ A;  1H2C A; 
#chains in the Genus database with same CATH topology
 2O19 A;  1CY6 A;  2GAI A;  4LDM A;  4CHT A;  1ECL A;  3PWT A;  1H2D A;  4HI5 A;  3PX7 A;  1CY1 A;  1CY4 A;  4HIU A;  3TCQ A;  2O5C A;  1MW8 X;  4HIT A;  4LDD A;  1I7D A;  1CY7 A;  1CY0 A;  1CY2 A;  4D4T A;  4RUL A;  5D5H A;  4G1L A;  4LDB A;  4HIW A;  2YKD A;  4G1G A;  4G1O A;  4V23 A;  1ES6 A;  1MW9 X;  4HIY A;  4CGY A;  1D6M A;  1H2C A;  4HI6 A;  1CYY A;  1CY9 A;  3F1J A;  5B0V A;  2O5E A;  2O54 A;  4LP7 A;  4LD8 A;  2GAJ A;  1CY8 A;  2O59 A;  2VQP A; 
#chains in the Genus database with same CATH homology
 4LDM A;  1H2D A;  4HI5 A;  4HIU A;  3TCQ A;  4HIT A;  4LDD A;  4D4T A;  4G1L A;  4LDB A;  4HIW A;  2YKD A;  4G1G A;  4G1O A;  4V23 A;  1ES6 A;  4HIY A;  1H2C A;  4HI6 A;  3F1J A;  5B0V A;  4LP7 A;  4LD8 A;  2VQP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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