1XB0A

Structure of the bir domain of iap-like protein 2
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
92
structure length
92
Chain Sequence
TNLPRNPSMTGYEARLITFGTWMYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 8
total genus 24
structure length 92
sequence length 92
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2004-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 1xb0A00
2UVLA 2OPYA 3UW5A 1QBHA 4EB9A 3HL5A 4HY4A 4LGEA 1SE0A 3MUPA 5C3HA 4MTIA 4KMNA 1XOXA 2VM5A 2VSLA 3UIIA 4HY5A 3F7GA 4J48A 4A0IA 4MU7A 2QRAA 5C7DA 5C7BA 3UEDA 4J47A 4J45A 1F9XA 2RAWA 5C7AA 2QFAA 1E31A 1M4MA 3UEHA 5C84A 4WVTA 4J46A 3M0DD 3OZ1A 4OXCA 3CM2A 1TFTA 3UIGA 1TW6A 3T6PA 1XB0A 2POIA 3G76A 2I3IA 3UIHA 1I3OE 1JD5A 4MTZA 4LGUA 3UEIA 1TFQA 3F7HA 2JK7A 4KJUA 2POPB 1G3FA 1G73C 4HY0A 5C0KA 4EC4A 3UEGA 5C0LA 4A0NA 3D9TA 3CLXA 4WVSA 1Q4QA 3GT9A 4J44A 3M0AD 1SDZA 4WVUA 1OXNA 3UECA 3M1DA 1F3HA 5C7CA 1NW9A 3GTAA 4J3YA 4A0JA 3UIJA 3CM7A 2OPZA 3UEFA 4KMPA 3EYLA 3SIQA 1OY7A 3UEEA 1JD4A 1C9QA 3UW4A 2RAXA 3F7IA 2I3HA 5C3KA 4KJVA 1XB1A 5C83A 3D9UA 3UIKA 1JD6A 1OXQA 3SIPE
chains in the Genus database with same CATH superfamily
2UVLA 2OPYA 3UW5A 1QBHA 4EB9A 3HL5A 4HY4A 4LGEA 1SE0A 3MUPA 5C3HA 4MTIA 4KMNA 1XOXA 2VM5A 2VSLA 3UIIA 4HY5A 3F7GA 4J48A 4A0IA 4MU7A 2QRAA 5C7DA 5C7BA 3UEDA 4J47A 4J45A 1F9XA 2RAWA 5C7AA 2QFAA 1E31A 1M4MA 3UEHA 5C84A 4WVTA 4J46A 3M0DD 3OZ1A 4OXCA 3CM2A 1TFTA 3UIGA 1TW6A 3T6PA 1XB0A 2POIA 3G76A 2I3IA 3UIHA 1I3OE 1JD5A 4MTZA 4LGUA 3UEIA 1TFQA 3F7HA 2JK7A 4KJUA 2POPB 1G3FA 1G73C 4HY0A 5C0KA 4EC4A 3UEGA 5C0LA 4A0NA 3D9TA 3CLXA 4WVSA 1Q4QA 3GT9A 4J44A 3M0AD 1SDZA 4WVUA 1OXNA 3UECA 3M1DA 1F3HA 5C7CA 1NW9A 3GTAA 4J3YA 4A0JA 3UIJA 3CM7A 2OPZA 3UEFA 4KMPA 3EYLA 3SIQA 1OY7A 3UEEA 1JD4A 1C9QA 3UW4A 2RAXA 3F7IA 2I3HA 5C3KA 4KJVA 1XB1A 5C83A 3D9UA 3UIKA 1JD6A 1OXQA 3SIPE
chains in the Genus database with same CATH topology
2UVLA 2OPYA 3UW5A 1QBHA 4EB9A 3HL5A 4HY4A 4LGEA 1SE0A 3MUPA 5C3HA 4MTIA 4KMNA 1XOXA 2VM5A 2VSLA 3UIIA 4HY5A 3F7GA 4J48A 4A0IA 4MU7A 2QRAA 5C7DA 5C7BA 3UEDA 4J47A 4J45A 1F9XA 2RAWA 5C7AA 2QFAA 1E31A 1M4MA 3UEHA 5C84A 4WVTA 4J46A 3M0DD 3OZ1A 4OXCA 3CM2A 1TFTA 3UIGA 1TW6A 3T6PA 1XB0A 2POIA 3G76A 2I3IA 3UIHA 1I3OE 1JD5A 4MTZA 4LGUA 3UEIA 1TFQA 3F7HA 2JK7A 4KJUA 2POPB 1G3FA 1G73C 4HY0A 5C0KA 4EC4A 3UEGA 5C0LA 4A0NA 3D9TA 3CLXA 4WVSA 1Q4QA 3GT9A 4J44A 3M0AD 1SDZA 4WVUA 1OXNA 3UECA 3M1DA 1F3HA 5C7CA 1NW9A 3GTAA 4J3YA 4A0JA 3UIJA 3CM7A 2OPZA 3UEFA 4KMPA 3EYLA 3SIQA 1OY7A 3UEEA 1JD4A 1C9QA 3UW4A 2RAXA 3F7IA 2I3HA 5C3KA 4KJVA 1XB1A 5C83A 3D9UA 3UIKA 1JD6A 1OXQA 3SIPE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2UVL A;  2OPY A;  3UW5 A;  1QBH A;  4EB9 A;  3HL5 A;  4HY4 A;  4LGE A;  1SE0 A;  3MUP A;  5C3H A;  4MTI A;  4KMN A;  1XOX A;  2VM5 A;  2VSL A;  3UII A;  4HY5 A;  3F7G A;  4J48 A;  4A0I A;  4MU7 A;  2QRA A;  5C7D A;  5C7B A;  3UED A;  4J47 A;  4J45 A;  1F9X A;  2RAW A;  5C7A A;  2QFA A;  1E31 A;  1M4M A;  3UEH A;  5C84 A;  4WVT A;  4J46 A;  3M0D D;  3OZ1 A;  4OXC A;  3CM2 A;  1TFT A;  3UIG A;  1TW6 A;  3T6P A;  1XB0 A;  2POI A;  3G76 A;  2I3I A;  3UIH A;  1I3O E;  1JD5 A;  4MTZ A;  4LGU A;  3UEI A;  1TFQ A;  3F7H A;  2JK7 A;  4KJU A;  2POP B;  1G3F A;  1G73 C;  4HY0 A;  5C0K A;  4EC4 A;  3UEG A;  5C0L A;  4A0N A;  3D9T A;  3CLX A;  4WVS A;  1Q4Q A;  3GT9 A;  4J44 A;  3M0A D;  1SDZ A;  4WVU A;  1OXN A;  3UEC A;  3M1D A;  1F3H A;  5C7C A;  1NW9 A;  3GTA A;  4J3Y A;  4A0J A;  3UIJ A;  3CM7 A;  2OPZ A;  3UEF A;  4KMP A;  3EYL A;  3SIQ A;  1OY7 A;  3UEE A;  1JD4 A;  1C9Q A;  3UW4 A;  2RAX A;  3F7I A;  2I3H A;  5C3K A;  4KJV A;  1XB1 A;  5C83 A;  3D9U A;  3UIK A;  1JD6 A;  1OXQ A;  3SIP E; 
#chains in the Genus database with same CATH topology
 2UVL A;  2OPY A;  3UW5 A;  1QBH A;  4EB9 A;  3HL5 A;  4HY4 A;  4LGE A;  1SE0 A;  3MUP A;  5C3H A;  4MTI A;  4KMN A;  1XOX A;  2VM5 A;  2VSL A;  3UII A;  4HY5 A;  3F7G A;  4J48 A;  4A0I A;  4MU7 A;  2QRA A;  5C7D A;  5C7B A;  3UED A;  4J47 A;  4J45 A;  1F9X A;  2RAW A;  5C7A A;  2QFA A;  1E31 A;  1M4M A;  3UEH A;  5C84 A;  4WVT A;  4J46 A;  3M0D D;  3OZ1 A;  4OXC A;  3CM2 A;  1TFT A;  3UIG A;  1TW6 A;  3T6P A;  1XB0 A;  2POI A;  3G76 A;  2I3I A;  3UIH A;  1I3O E;  1JD5 A;  4MTZ A;  4LGU A;  3UEI A;  1TFQ A;  3F7H A;  2JK7 A;  4KJU A;  2POP B;  1G3F A;  1G73 C;  4HY0 A;  5C0K A;  4EC4 A;  3UEG A;  5C0L A;  4A0N A;  3D9T A;  3CLX A;  4WVS A;  1Q4Q A;  3GT9 A;  4J44 A;  3M0A D;  1SDZ A;  4WVU A;  1OXN A;  3UEC A;  3M1D A;  1F3H A;  5C7C A;  1NW9 A;  3GTA A;  4J3Y A;  4A0J A;  3UIJ A;  3CM7 A;  2OPZ A;  3UEF A;  4KMP A;  3EYL A;  3SIQ A;  1OY7 A;  3UEE A;  1JD4 A;  1C9Q A;  3UW4 A;  2RAX A;  3F7I A;  2I3H A;  5C3K A;  4KJV A;  1XB1 A;  5C83 A;  3D9U A;  3UIK A;  1JD6 A;  1OXQ A;  3SIP E; 
#chains in the Genus database with same CATH homology
 2UVL A;  2OPY A;  3UW5 A;  1QBH A;  4EB9 A;  3HL5 A;  4HY4 A;  4LGE A;  1SE0 A;  3MUP A;  5C3H A;  4MTI A;  4KMN A;  1XOX A;  2VM5 A;  2VSL A;  3UII A;  4HY5 A;  3F7G A;  4J48 A;  4A0I A;  4MU7 A;  2QRA A;  5C7D A;  5C7B A;  3UED A;  4J47 A;  4J45 A;  1F9X A;  2RAW A;  5C7A A;  2QFA A;  1E31 A;  1M4M A;  3UEH A;  5C84 A;  4WVT A;  4J46 A;  3M0D D;  3OZ1 A;  4OXC A;  3CM2 A;  1TFT A;  3UIG A;  1TW6 A;  3T6P A;  1XB0 A;  2POI A;  3G76 A;  2I3I A;  3UIH A;  1I3O E;  1JD5 A;  4MTZ A;  4LGU A;  3UEI A;  1TFQ A;  3F7H A;  2JK7 A;  4KJU A;  2POP B;  1G3F A;  1G73 C;  4HY0 A;  5C0K A;  4EC4 A;  3UEG A;  5C0L A;  4A0N A;  3D9T A;  3CLX A;  4WVS A;  1Q4Q A;  3GT9 A;  4J44 A;  3M0A D;  1SDZ A;  4WVU A;  1OXN A;  3UEC A;  3M1D A;  1F3H A;  5C7C A;  1NW9 A;  3GTA A;  4J3Y A;  4A0J A;  3UIJ A;  3CM7 A;  2OPZ A;  3UEF A;  4KMP A;  3EYL A;  3SIQ A;  1OY7 A;  3UEE A;  1JD4 A;  1C9Q A;  3UW4 A;  2RAX A;  3F7I A;  2I3H A;  5C3K A;  4KJV A;  1XB1 A;  5C83 A;  3D9U A;  3UIK A;  1JD6 A;  1OXQ A;  3SIP E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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