1C9QA

Average nmr solution structure of the bir-2 domain of xiap
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
117
structure length
117
Chain Sequence
RDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGRNLNIRSE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords APOPTOSIS INHIBITOR IAP HOMOLOG
total genus 13
structure length 117
sequence length 117
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 1999-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 1c9qA00
1C9QA 4J46A 1XB0A 3UEGA 3UEFA 5C7CA 1OXNA 2POPB 4J3YA 1E31A 3CM2A 4A0JA 3G76A 3CM7A 3M1DA 1SE0A 4WVTA 1JD6A 3UW5A 1TFTA 1TW6A 3M0DD 5C83A 4MU7A 3T6PA 1JD4A 4KJVA 5C7DA 3UEEA 2UVLA 3GT9A 4KMNA 1XOXA 2VM5A 4HY5A 3GTAA 1G3FA 3CLXA 2RAXA 2QFAA 3UEIA 2OPZA 3F7IA 3F7GA 4J45A 3SIPE 3UIGA 1QBHA 5C84A 3D9UA 4EC4A 3UECA 4J47A 3UIHA 4OXCA 2VSLA 4HY4A 3UW4A 1JD5A 4KJUA 4J48A 4A0IA 4WVUA 1OXQA 3OZ1A 4EB9A 1G73C 3UIIA 1F9XA 4WVSA 3M0AD 3HL5A 4HY0A 5C7BA 5C3KA 2JK7A 1I3OE 2POIA 3SIQA 3D9TA 2I3IA 4J44A 4LGUA 2I3HA 4MTZA 1M4MA 1NW9A 2OPYA 3F7HA 1OY7A 3UEDA 5C0KA 1Q4QA 3EYLA 4KMPA 5C7AA 4A0NA 3MUPA 2QRAA 5C3HA 3UIJA 1SDZA 2RAWA 1F3HA 5C0LA 1XB1A 4MTIA 3UIKA 1TFQA 3UEHA 4LGEA
chains in the Genus database with same CATH superfamily
1C9QA 4J46A 1XB0A 3UEGA 3UEFA 5C7CA 1OXNA 2POPB 4J3YA 1E31A 3CM2A 4A0JA 3G76A 3CM7A 3M1DA 1SE0A 4WVTA 1JD6A 3UW5A 1TFTA 1TW6A 3M0DD 5C83A 4MU7A 3T6PA 1JD4A 4KJVA 5C7DA 3UEEA 2UVLA 3GT9A 4KMNA 1XOXA 2VM5A 4HY5A 3GTAA 1G3FA 3CLXA 2RAXA 2QFAA 3UEIA 2OPZA 3F7IA 3F7GA 4J45A 3SIPE 3UIGA 1QBHA 5C84A 3D9UA 4EC4A 3UECA 4J47A 3UIHA 4OXCA 2VSLA 4HY4A 3UW4A 1JD5A 4KJUA 4J48A 4A0IA 4WVUA 1OXQA 3OZ1A 4EB9A 1G73C 3UIIA 1F9XA 4WVSA 3M0AD 3HL5A 4HY0A 5C7BA 5C3KA 2JK7A 1I3OE 2POIA 3SIQA 3D9TA 2I3IA 4J44A 4LGUA 2I3HA 4MTZA 1M4MA 1NW9A 2OPYA 3F7HA 1OY7A 3UEDA 5C0KA 1Q4QA 3EYLA 4KMPA 5C7AA 4A0NA 3MUPA 2QRAA 5C3HA 3UIJA 1SDZA 2RAWA 1F3HA 5C0LA 1XB1A 4MTIA 3UIKA 1TFQA 3UEHA 4LGEA
chains in the Genus database with same CATH topology
1C9QA 4J46A 1XB0A 3UEGA 3UEFA 5C7CA 1OXNA 2POPB 4J3YA 1E31A 3CM2A 4A0JA 3G76A 3CM7A 3M1DA 1SE0A 4WVTA 1JD6A 3UW5A 1TFTA 1TW6A 3M0DD 5C83A 4MU7A 3T6PA 1JD4A 4KJVA 5C7DA 3UEEA 2UVLA 3GT9A 4KMNA 1XOXA 2VM5A 4HY5A 3GTAA 1G3FA 3CLXA 2RAXA 2QFAA 3UEIA 2OPZA 3F7IA 3F7GA 4J45A 3SIPE 3UIGA 1QBHA 5C84A 3D9UA 4EC4A 3UECA 4J47A 3UIHA 4OXCA 2VSLA 4HY4A 3UW4A 1JD5A 4KJUA 4J48A 4A0IA 4WVUA 1OXQA 3OZ1A 4EB9A 1G73C 3UIIA 1F9XA 4WVSA 3M0AD 3HL5A 4HY0A 5C7BA 5C3KA 2JK7A 1I3OE 2POIA 3SIQA 3D9TA 2I3IA 4J44A 4LGUA 2I3HA 4MTZA 1M4MA 1NW9A 2OPYA 3F7HA 1OY7A 3UEDA 5C0KA 1Q4QA 3EYLA 4KMPA 5C7AA 4A0NA 3MUPA 2QRAA 5C3HA 3UIJA 1SDZA 2RAWA 1F3HA 5C0LA 1XB1A 4MTIA 3UIKA 1TFQA 3UEHA 4LGEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C9Q A;  4J46 A;  1XB0 A;  3UEG A;  3UEF A;  5C7C A;  1OXN A;  2POP B;  4J3Y A;  1E31 A;  3CM2 A;  4A0J A;  3G76 A;  3CM7 A;  3M1D A;  1SE0 A;  4WVT A;  1JD6 A;  3UW5 A;  1TFT A;  1TW6 A;  3M0D D;  5C83 A;  4MU7 A;  3T6P A;  1JD4 A;  4KJV A;  5C7D A;  3UEE A;  2UVL A;  3GT9 A;  4KMN A;  1XOX A;  2VM5 A;  4HY5 A;  3GTA A;  1G3F A;  3CLX A;  2RAX A;  2QFA A;  3UEI A;  2OPZ A;  3F7I A;  3F7G A;  4J45 A;  3SIP E;  3UIG A;  1QBH A;  5C84 A;  3D9U A;  4EC4 A;  3UEC A;  4J47 A;  3UIH A;  4OXC A;  2VSL A;  4HY4 A;  3UW4 A;  1JD5 A;  4KJU A;  4J48 A;  4A0I A;  4WVU A;  1OXQ A;  3OZ1 A;  4EB9 A;  1G73 C;  3UII A;  1F9X A;  4WVS A;  3M0A D;  3HL5 A;  4HY0 A;  5C7B A;  5C3K A;  2JK7 A;  1I3O E;  2POI A;  3SIQ A;  3D9T A;  2I3I A;  4J44 A;  4LGU A;  2I3H A;  4MTZ A;  1M4M A;  1NW9 A;  2OPY A;  3F7H A;  1OY7 A;  3UED A;  5C0K A;  1Q4Q A;  3EYL A;  4KMP A;  5C7A A;  4A0N A;  3MUP A;  2QRA A;  5C3H A;  3UIJ A;  1SDZ A;  2RAW A;  1F3H A;  5C0L A;  1XB1 A;  4MTI A;  3UIK A;  1TFQ A;  3UEH A;  4LGE A; 
#chains in the Genus database with same CATH topology
 1C9Q A;  4J46 A;  1XB0 A;  3UEG A;  3UEF A;  5C7C A;  1OXN A;  2POP B;  4J3Y A;  1E31 A;  3CM2 A;  4A0J A;  3G76 A;  3CM7 A;  3M1D A;  1SE0 A;  4WVT A;  1JD6 A;  3UW5 A;  1TFT A;  1TW6 A;  3M0D D;  5C83 A;  4MU7 A;  3T6P A;  1JD4 A;  4KJV A;  5C7D A;  3UEE A;  2UVL A;  3GT9 A;  4KMN A;  1XOX A;  2VM5 A;  4HY5 A;  3GTA A;  1G3F A;  3CLX A;  2RAX A;  2QFA A;  3UEI A;  2OPZ A;  3F7I A;  3F7G A;  4J45 A;  3SIP E;  3UIG A;  1QBH A;  5C84 A;  3D9U A;  4EC4 A;  3UEC A;  4J47 A;  3UIH A;  4OXC A;  2VSL A;  4HY4 A;  3UW4 A;  1JD5 A;  4KJU A;  4J48 A;  4A0I A;  4WVU A;  1OXQ A;  3OZ1 A;  4EB9 A;  1G73 C;  3UII A;  1F9X A;  4WVS A;  3M0A D;  3HL5 A;  4HY0 A;  5C7B A;  5C3K A;  2JK7 A;  1I3O E;  2POI A;  3SIQ A;  3D9T A;  2I3I A;  4J44 A;  4LGU A;  2I3H A;  4MTZ A;  1M4M A;  1NW9 A;  2OPY A;  3F7H A;  1OY7 A;  3UED A;  5C0K A;  1Q4Q A;  3EYL A;  4KMP A;  5C7A A;  4A0N A;  3MUP A;  2QRA A;  5C3H A;  3UIJ A;  1SDZ A;  2RAW A;  1F3H A;  5C0L A;  1XB1 A;  4MTI A;  3UIK A;  1TFQ A;  3UEH A;  4LGE A; 
#chains in the Genus database with same CATH homology
 1C9Q A;  4J46 A;  1XB0 A;  3UEG A;  3UEF A;  5C7C A;  1OXN A;  2POP B;  4J3Y A;  1E31 A;  3CM2 A;  4A0J A;  3G76 A;  3CM7 A;  3M1D A;  1SE0 A;  4WVT A;  1JD6 A;  3UW5 A;  1TFT A;  1TW6 A;  3M0D D;  5C83 A;  4MU7 A;  3T6P A;  1JD4 A;  4KJV A;  5C7D A;  3UEE A;  2UVL A;  3GT9 A;  4KMN A;  1XOX A;  2VM5 A;  4HY5 A;  3GTA A;  1G3F A;  3CLX A;  2RAX A;  2QFA A;  3UEI A;  2OPZ A;  3F7I A;  3F7G A;  4J45 A;  3SIP E;  3UIG A;  1QBH A;  5C84 A;  3D9U A;  4EC4 A;  3UEC A;  4J47 A;  3UIH A;  4OXC A;  2VSL A;  4HY4 A;  3UW4 A;  1JD5 A;  4KJU A;  4J48 A;  4A0I A;  4WVU A;  1OXQ A;  3OZ1 A;  4EB9 A;  1G73 C;  3UII A;  1F9X A;  4WVS A;  3M0A D;  3HL5 A;  4HY0 A;  5C7B A;  5C3K A;  2JK7 A;  1I3O E;  2POI A;  3SIQ A;  3D9T A;  2I3I A;  4J44 A;  4LGU A;  2I3H A;  4MTZ A;  1M4M A;  1NW9 A;  2OPY A;  3F7H A;  1OY7 A;  3UED A;  5C0K A;  1Q4Q A;  3EYL A;  4KMP A;  5C7A A;  4A0N A;  3MUP A;  2QRA A;  5C3H A;  3UIJ A;  1SDZ A;  2RAW A;  1F3H A;  5C0L A;  1XB1 A;  4MTI A;  3UIK A;  1TFQ A;  3UEH A;  4LGE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...