1G3FA

Nmr structure of a 9 residue peptide from smac/diablo complexed to the bir3 domain of xiap
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
117
structure length
117
Chain Sequence
MSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords INHIBITOR OF APOPTOSIS PROTEIN 3
total genus 21
structure length 117
sequence length 117
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2000-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 1g3fA00
3F7IA 3F7HA 1JD4A 1G3FA 3F7GA 3UIKA 4J45A 3D9UA 3UW4A 3UIJA 4MTIA 3UEFA 2OPZA 3UEDA 3UEIA 2OPYA 4LGUA 5C0LA 1OXQA 1TFQA 1G73C 5C84A 5C3HA 4A0JA 3GTAA 5C3KA 1NW9A 2JK7A 4MTZA 3T6PA 3HL5A 1OXNA 3SIQA 4WVUA 4A0NA 4J48A 1Q4QA 4HY0A 4KJVA 4J47A 4EC4A 3UEHA 1XB0A 4MU7A 4J46A 3UEEA 2POPB 2QRAA 1SE0A 2VM5A 3D9TA 1F3HA 2I3HA 4J44A 3M0DD 1SDZA 2UVLA 1M4MA 1OY7A 1JD5A 3M1DA 1XB1A 2POIA 1F9XA 3UECA 1QBHA 3UIHA 3UEGA 1TW6A 4A0IA 5C7DA 5C83A 3CLXA 4KJUA 5C7BA 1E31A 3SIPE 4EB9A 2VSLA 4HY5A 1TFTA 4OXCA 4HY4A 1XOXA 2I3IA 3OZ1A 1C9QA 4J3YA 5C0KA 3UIGA 2RAXA 1JD6A 4KMPA 2RAWA 4WVSA 3M0AD 1I3OE 3CM7A 5C7AA 3GT9A 3EYLA 3CM2A 3MUPA 4KMNA 3UIIA 5C7CA 3G76A 4LGEA 3UW5A 2QFAA 4WVTA
chains in the Genus database with same CATH superfamily
3F7IA 3F7HA 1JD4A 1G3FA 3F7GA 3UIKA 4J45A 3D9UA 3UW4A 3UIJA 4MTIA 3UEFA 2OPZA 3UEDA 3UEIA 2OPYA 4LGUA 5C0LA 1OXQA 1TFQA 1G73C 5C84A 5C3HA 4A0JA 3GTAA 5C3KA 1NW9A 2JK7A 4MTZA 3T6PA 3HL5A 1OXNA 3SIQA 4WVUA 4A0NA 4J48A 1Q4QA 4HY0A 4KJVA 4J47A 4EC4A 3UEHA 1XB0A 4MU7A 4J46A 3UEEA 2POPB 2QRAA 1SE0A 2VM5A 3D9TA 1F3HA 2I3HA 4J44A 3M0DD 1SDZA 2UVLA 1M4MA 1OY7A 1JD5A 3M1DA 1XB1A 2POIA 1F9XA 3UECA 1QBHA 3UIHA 3UEGA 1TW6A 4A0IA 5C7DA 5C83A 3CLXA 4KJUA 5C7BA 1E31A 3SIPE 4EB9A 2VSLA 4HY5A 1TFTA 4OXCA 4HY4A 1XOXA 2I3IA 3OZ1A 1C9QA 4J3YA 5C0KA 3UIGA 2RAXA 1JD6A 4KMPA 2RAWA 4WVSA 3M0AD 1I3OE 3CM7A 5C7AA 3GT9A 3EYLA 3CM2A 3MUPA 4KMNA 3UIIA 5C7CA 3G76A 4LGEA 3UW5A 2QFAA 4WVTA
chains in the Genus database with same CATH topology
3F7IA 3F7HA 1JD4A 1G3FA 3F7GA 3UIKA 4J45A 3D9UA 3UW4A 3UIJA 4MTIA 3UEFA 2OPZA 3UEDA 3UEIA 2OPYA 4LGUA 5C0LA 1OXQA 1TFQA 1G73C 5C84A 5C3HA 4A0JA 3GTAA 5C3KA 1NW9A 2JK7A 4MTZA 3T6PA 3HL5A 1OXNA 3SIQA 4WVUA 4A0NA 4J48A 1Q4QA 4HY0A 4KJVA 4J47A 4EC4A 3UEHA 1XB0A 4MU7A 4J46A 3UEEA 2POPB 2QRAA 1SE0A 2VM5A 3D9TA 1F3HA 2I3HA 4J44A 3M0DD 1SDZA 2UVLA 1M4MA 1OY7A 1JD5A 3M1DA 1XB1A 2POIA 1F9XA 3UECA 1QBHA 3UIHA 3UEGA 1TW6A 4A0IA 5C7DA 5C83A 3CLXA 4KJUA 5C7BA 1E31A 3SIPE 4EB9A 2VSLA 4HY5A 1TFTA 4OXCA 4HY4A 1XOXA 2I3IA 3OZ1A 1C9QA 4J3YA 5C0KA 3UIGA 2RAXA 1JD6A 4KMPA 2RAWA 4WVSA 3M0AD 1I3OE 3CM7A 5C7AA 3GT9A 3EYLA 3CM2A 3MUPA 4KMNA 3UIIA 5C7CA 3G76A 4LGEA 3UW5A 2QFAA 4WVTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F7I A;  3F7H A;  1JD4 A;  1G3F A;  3F7G A;  3UIK A;  4J45 A;  3D9U A;  3UW4 A;  3UIJ A;  4MTI A;  3UEF A;  2OPZ A;  3UED A;  3UEI A;  2OPY A;  4LGU A;  5C0L A;  1OXQ A;  1TFQ A;  1G73 C;  5C84 A;  5C3H A;  4A0J A;  3GTA A;  5C3K A;  1NW9 A;  2JK7 A;  4MTZ A;  3T6P A;  3HL5 A;  1OXN A;  3SIQ A;  4WVU A;  4A0N A;  4J48 A;  1Q4Q A;  4HY0 A;  4KJV A;  4J47 A;  4EC4 A;  3UEH A;  1XB0 A;  4MU7 A;  4J46 A;  3UEE A;  2POP B;  2QRA A;  1SE0 A;  2VM5 A;  3D9T A;  1F3H A;  2I3H A;  4J44 A;  3M0D D;  1SDZ A;  2UVL A;  1M4M A;  1OY7 A;  1JD5 A;  3M1D A;  1XB1 A;  2POI A;  1F9X A;  3UEC A;  1QBH A;  3UIH A;  3UEG A;  1TW6 A;  4A0I A;  5C7D A;  5C83 A;  3CLX A;  4KJU A;  5C7B A;  1E31 A;  3SIP E;  4EB9 A;  2VSL A;  4HY5 A;  1TFT A;  4OXC A;  4HY4 A;  1XOX A;  2I3I A;  3OZ1 A;  1C9Q A;  4J3Y A;  5C0K A;  3UIG A;  2RAX A;  1JD6 A;  4KMP A;  2RAW A;  4WVS A;  3M0A D;  1I3O E;  3CM7 A;  5C7A A;  3GT9 A;  3EYL A;  3CM2 A;  3MUP A;  4KMN A;  3UII A;  5C7C A;  3G76 A;  4LGE A;  3UW5 A;  2QFA A;  4WVT A; 
#chains in the Genus database with same CATH topology
 3F7I A;  3F7H A;  1JD4 A;  1G3F A;  3F7G A;  3UIK A;  4J45 A;  3D9U A;  3UW4 A;  3UIJ A;  4MTI A;  3UEF A;  2OPZ A;  3UED A;  3UEI A;  2OPY A;  4LGU A;  5C0L A;  1OXQ A;  1TFQ A;  1G73 C;  5C84 A;  5C3H A;  4A0J A;  3GTA A;  5C3K A;  1NW9 A;  2JK7 A;  4MTZ A;  3T6P A;  3HL5 A;  1OXN A;  3SIQ A;  4WVU A;  4A0N A;  4J48 A;  1Q4Q A;  4HY0 A;  4KJV A;  4J47 A;  4EC4 A;  3UEH A;  1XB0 A;  4MU7 A;  4J46 A;  3UEE A;  2POP B;  2QRA A;  1SE0 A;  2VM5 A;  3D9T A;  1F3H A;  2I3H A;  4J44 A;  3M0D D;  1SDZ A;  2UVL A;  1M4M A;  1OY7 A;  1JD5 A;  3M1D A;  1XB1 A;  2POI A;  1F9X A;  3UEC A;  1QBH A;  3UIH A;  3UEG A;  1TW6 A;  4A0I A;  5C7D A;  5C83 A;  3CLX A;  4KJU A;  5C7B A;  1E31 A;  3SIP E;  4EB9 A;  2VSL A;  4HY5 A;  1TFT A;  4OXC A;  4HY4 A;  1XOX A;  2I3I A;  3OZ1 A;  1C9Q A;  4J3Y A;  5C0K A;  3UIG A;  2RAX A;  1JD6 A;  4KMP A;  2RAW A;  4WVS A;  3M0A D;  1I3O E;  3CM7 A;  5C7A A;  3GT9 A;  3EYL A;  3CM2 A;  3MUP A;  4KMN A;  3UII A;  5C7C A;  3G76 A;  4LGE A;  3UW5 A;  2QFA A;  4WVT A; 
#chains in the Genus database with same CATH homology
 3F7I A;  3F7H A;  1JD4 A;  1G3F A;  3F7G A;  3UIK A;  4J45 A;  3D9U A;  3UW4 A;  3UIJ A;  4MTI A;  3UEF A;  2OPZ A;  3UED A;  3UEI A;  2OPY A;  4LGU A;  5C0L A;  1OXQ A;  1TFQ A;  1G73 C;  5C84 A;  5C3H A;  4A0J A;  3GTA A;  5C3K A;  1NW9 A;  2JK7 A;  4MTZ A;  3T6P A;  3HL5 A;  1OXN A;  3SIQ A;  4WVU A;  4A0N A;  4J48 A;  1Q4Q A;  4HY0 A;  4KJV A;  4J47 A;  4EC4 A;  3UEH A;  1XB0 A;  4MU7 A;  4J46 A;  3UEE A;  2POP B;  2QRA A;  1SE0 A;  2VM5 A;  3D9T A;  1F3H A;  2I3H A;  4J44 A;  3M0D D;  1SDZ A;  2UVL A;  1M4M A;  1OY7 A;  1JD5 A;  3M1D A;  1XB1 A;  2POI A;  1F9X A;  3UEC A;  1QBH A;  3UIH A;  3UEG A;  1TW6 A;  4A0I A;  5C7D A;  5C83 A;  3CLX A;  4KJU A;  5C7B A;  1E31 A;  3SIP E;  4EB9 A;  2VSL A;  4HY5 A;  1TFT A;  4OXC A;  4HY4 A;  1XOX A;  2I3I A;  3OZ1 A;  1C9Q A;  4J3Y A;  5C0K A;  3UIG A;  2RAX A;  1JD6 A;  4KMP A;  2RAW A;  4WVS A;  3M0A D;  1I3O E;  3CM7 A;  5C7A A;  3GT9 A;  3EYL A;  3CM2 A;  3MUP A;  4KMN A;  3UII A;  5C7C A;  3G76 A;  4LGE A;  3UW5 A;  2QFA A;  4WVT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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