1NW9A

Structure of caspase-9 in an inhibitory complex with xiap-bir3
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
91
structure length
91
Chain Sequence
LPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism of XIAP-Mediated Inhibition of Caspase-9
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 25
structure length 91
sequence length 91
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2003-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 1nw9A00
4KMNA 1XB0A 3F7IA 4A0NA 1C9QA 3GTAA 5C7CA 1SE0A 3G76A 3UIKA 2QRAA 2OPZA 5C7AA 4J44A 4MTIA 4A0JA 3UEEA 2OPYA 4WVSA 4KJVA 1XOXA 1JD4A 2VM5A 4MTZA 4J3YA 5C3KA 4EC4A 3F7GA 2VSLA 1TFQA 1TFTA 4WVUA 1TW6A 5C3HA 5C84A 3SIPE 3UIIA 1QBHA 3M0AD 3UIJA 5C83A 1G3FA 2RAWA 4A0IA 3EYLA 4J45A 3HL5A 5C7BA 3CM2A 3UEHA 1OXNA 3M0DD 4WVTA 5C0KA 4EB9A 1E31A 1JD6A 3D9UA 1XB1A 4LGUA 3UECA 3MUPA 3D9TA 1OXQA 1Q4QA 3UEGA 1SDZA 3UIHA 1G73C 3T6PA 4J48A 1F9XA 1M4MA 2I3IA 3UEFA 1NW9A 3GT9A 5C7DA 5C0LA 3SIQA 3M1DA 1JD5A 2POPB 4KMPA 4LGEA 4J46A 4HY4A 2JK7A 3UIGA 2I3HA 2UVLA 3OZ1A 1F3HA 3F7HA 2POIA 3CM7A 1OY7A 3CLXA 4MU7A 1I3OE 3UW4A 4HY0A 2QFAA 2RAXA 4HY5A 4J47A 4OXCA 3UEIA 3UEDA 4KJUA 3UW5A
chains in the Genus database with same CATH superfamily
4KMNA 1XB0A 3F7IA 4A0NA 1C9QA 3GTAA 5C7CA 1SE0A 3G76A 3UIKA 2QRAA 2OPZA 5C7AA 4J44A 4MTIA 4A0JA 3UEEA 2OPYA 4WVSA 4KJVA 1XOXA 1JD4A 2VM5A 4MTZA 4J3YA 5C3KA 4EC4A 3F7GA 2VSLA 1TFQA 1TFTA 4WVUA 1TW6A 5C3HA 5C84A 3SIPE 3UIIA 1QBHA 3M0AD 3UIJA 5C83A 1G3FA 2RAWA 4A0IA 3EYLA 4J45A 3HL5A 5C7BA 3CM2A 3UEHA 1OXNA 3M0DD 4WVTA 5C0KA 4EB9A 1E31A 1JD6A 3D9UA 1XB1A 4LGUA 3UECA 3MUPA 3D9TA 1OXQA 1Q4QA 3UEGA 1SDZA 3UIHA 1G73C 3T6PA 4J48A 1F9XA 1M4MA 2I3IA 3UEFA 1NW9A 3GT9A 5C7DA 5C0LA 3SIQA 3M1DA 1JD5A 2POPB 4KMPA 4LGEA 4J46A 4HY4A 2JK7A 3UIGA 2I3HA 2UVLA 3OZ1A 1F3HA 3F7HA 2POIA 3CM7A 1OY7A 3CLXA 4MU7A 1I3OE 3UW4A 4HY0A 2QFAA 2RAXA 4HY5A 4J47A 4OXCA 3UEIA 3UEDA 4KJUA 3UW5A
chains in the Genus database with same CATH topology
4KMNA 1XB0A 3F7IA 4A0NA 1C9QA 3GTAA 5C7CA 1SE0A 3G76A 3UIKA 2QRAA 2OPZA 5C7AA 4J44A 4MTIA 4A0JA 3UEEA 2OPYA 4WVSA 4KJVA 1XOXA 1JD4A 2VM5A 4MTZA 4J3YA 5C3KA 4EC4A 3F7GA 2VSLA 1TFQA 1TFTA 4WVUA 1TW6A 5C3HA 5C84A 3SIPE 3UIIA 1QBHA 3M0AD 3UIJA 5C83A 1G3FA 2RAWA 4A0IA 3EYLA 4J45A 3HL5A 5C7BA 3CM2A 3UEHA 1OXNA 3M0DD 4WVTA 5C0KA 4EB9A 1E31A 1JD6A 3D9UA 1XB1A 4LGUA 3UECA 3MUPA 3D9TA 1OXQA 1Q4QA 3UEGA 1SDZA 3UIHA 1G73C 3T6PA 4J48A 1F9XA 1M4MA 2I3IA 3UEFA 1NW9A 3GT9A 5C7DA 5C0LA 3SIQA 3M1DA 1JD5A 2POPB 4KMPA 4LGEA 4J46A 4HY4A 2JK7A 3UIGA 2I3HA 2UVLA 3OZ1A 1F3HA 3F7HA 2POIA 3CM7A 1OY7A 3CLXA 4MU7A 1I3OE 3UW4A 4HY0A 2QFAA 2RAXA 4HY5A 4J47A 4OXCA 3UEIA 3UEDA 4KJUA 3UW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KMN A;  1XB0 A;  3F7I A;  4A0N A;  1C9Q A;  3GTA A;  5C7C A;  1SE0 A;  3G76 A;  3UIK A;  2QRA A;  2OPZ A;  5C7A A;  4J44 A;  4MTI A;  4A0J A;  3UEE A;  2OPY A;  4WVS A;  4KJV A;  1XOX A;  1JD4 A;  2VM5 A;  4MTZ A;  4J3Y A;  5C3K A;  4EC4 A;  3F7G A;  2VSL A;  1TFQ A;  1TFT A;  4WVU A;  1TW6 A;  5C3H A;  5C84 A;  3SIP E;  3UII A;  1QBH A;  3M0A D;  3UIJ A;  5C83 A;  1G3F A;  2RAW A;  4A0I A;  3EYL A;  4J45 A;  3HL5 A;  5C7B A;  3CM2 A;  3UEH A;  1OXN A;  3M0D D;  4WVT A;  5C0K A;  4EB9 A;  1E31 A;  1JD6 A;  3D9U A;  1XB1 A;  4LGU A;  3UEC A;  3MUP A;  3D9T A;  1OXQ A;  1Q4Q A;  3UEG A;  1SDZ A;  3UIH A;  1G73 C;  3T6P A;  4J48 A;  1F9X A;  1M4M A;  2I3I A;  3UEF A;  1NW9 A;  3GT9 A;  5C7D A;  5C0L A;  3SIQ A;  3M1D A;  1JD5 A;  2POP B;  4KMP A;  4LGE A;  4J46 A;  4HY4 A;  2JK7 A;  3UIG A;  2I3H A;  2UVL A;  3OZ1 A;  1F3H A;  3F7H A;  2POI A;  3CM7 A;  1OY7 A;  3CLX A;  4MU7 A;  1I3O E;  3UW4 A;  4HY0 A;  2QFA A;  2RAX A;  4HY5 A;  4J47 A;  4OXC A;  3UEI A;  3UED A;  4KJU A;  3UW5 A; 
#chains in the Genus database with same CATH topology
 4KMN A;  1XB0 A;  3F7I A;  4A0N A;  1C9Q A;  3GTA A;  5C7C A;  1SE0 A;  3G76 A;  3UIK A;  2QRA A;  2OPZ A;  5C7A A;  4J44 A;  4MTI A;  4A0J A;  3UEE A;  2OPY A;  4WVS A;  4KJV A;  1XOX A;  1JD4 A;  2VM5 A;  4MTZ A;  4J3Y A;  5C3K A;  4EC4 A;  3F7G A;  2VSL A;  1TFQ A;  1TFT A;  4WVU A;  1TW6 A;  5C3H A;  5C84 A;  3SIP E;  3UII A;  1QBH A;  3M0A D;  3UIJ A;  5C83 A;  1G3F A;  2RAW A;  4A0I A;  3EYL A;  4J45 A;  3HL5 A;  5C7B A;  3CM2 A;  3UEH A;  1OXN A;  3M0D D;  4WVT A;  5C0K A;  4EB9 A;  1E31 A;  1JD6 A;  3D9U A;  1XB1 A;  4LGU A;  3UEC A;  3MUP A;  3D9T A;  1OXQ A;  1Q4Q A;  3UEG A;  1SDZ A;  3UIH A;  1G73 C;  3T6P A;  4J48 A;  1F9X A;  1M4M A;  2I3I A;  3UEF A;  1NW9 A;  3GT9 A;  5C7D A;  5C0L A;  3SIQ A;  3M1D A;  1JD5 A;  2POP B;  4KMP A;  4LGE A;  4J46 A;  4HY4 A;  2JK7 A;  3UIG A;  2I3H A;  2UVL A;  3OZ1 A;  1F3H A;  3F7H A;  2POI A;  3CM7 A;  1OY7 A;  3CLX A;  4MU7 A;  1I3O E;  3UW4 A;  4HY0 A;  2QFA A;  2RAX A;  4HY5 A;  4J47 A;  4OXC A;  3UEI A;  3UED A;  4KJU A;  3UW5 A; 
#chains in the Genus database with same CATH homology
 4KMN A;  1XB0 A;  3F7I A;  4A0N A;  1C9Q A;  3GTA A;  5C7C A;  1SE0 A;  3G76 A;  3UIK A;  2QRA A;  2OPZ A;  5C7A A;  4J44 A;  4MTI A;  4A0J A;  3UEE A;  2OPY A;  4WVS A;  4KJV A;  1XOX A;  1JD4 A;  2VM5 A;  4MTZ A;  4J3Y A;  5C3K A;  4EC4 A;  3F7G A;  2VSL A;  1TFQ A;  1TFT A;  4WVU A;  1TW6 A;  5C3H A;  5C84 A;  3SIP E;  3UII A;  1QBH A;  3M0A D;  3UIJ A;  5C83 A;  1G3F A;  2RAW A;  4A0I A;  3EYL A;  4J45 A;  3HL5 A;  5C7B A;  3CM2 A;  3UEH A;  1OXN A;  3M0D D;  4WVT A;  5C0K A;  4EB9 A;  1E31 A;  1JD6 A;  3D9U A;  1XB1 A;  4LGU A;  3UEC A;  3MUP A;  3D9T A;  1OXQ A;  1Q4Q A;  3UEG A;  1SDZ A;  3UIH A;  1G73 C;  3T6P A;  4J48 A;  1F9X A;  1M4M A;  2I3I A;  3UEF A;  1NW9 A;  3GT9 A;  5C7D A;  5C0L A;  3SIQ A;  3M1D A;  1JD5 A;  2POP B;  4KMP A;  4LGE A;  4J46 A;  4HY4 A;  2JK7 A;  3UIG A;  2I3H A;  2UVL A;  3OZ1 A;  1F3H A;  3F7H A;  2POI A;  3CM7 A;  1OY7 A;  3CLX A;  4MU7 A;  1I3O E;  3UW4 A;  4HY0 A;  2QFA A;  2RAX A;  4HY5 A;  4J47 A;  4OXC A;  3UEI A;  3UED A;  4KJU A;  3UW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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