1SDZA

Crystal structure of diap1 bir1 bound to a reaper peptide
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
97
structure length
97
Chain Sequence
NDLNREETRLKTFTDWPLDWLDKRQLAQTGMYFTHAGDKVKCFFCGVEIGSWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEALDRILPPISYD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
pubmed doi rcsb
molecule tags Apoptosis
source organism Drosophila melanogaster
molecule keywords Apoptosis 1 inhibitor
total genus 26
structure length 97
sequence length 97
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2004-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 1sdzA00
2QRAA 3UEIA 4HY5A 1JD5A 1XB0A 4A0IA 3F7HA 3GT9A 4J47A 3OZ1A 3UIHA 5C3HA 1M4MA 2POPB 1TW6A 1C9QA 2UVLA 4J45A 4LGUA 1XB1A 2RAXA 1TFTA 1G73C 1F3HA 3CM7A 2I3HA 2OPZA 2JK7A 3UIKA 4A0JA 2VSLA 1E31A 3G76A 3UEDA 4WVTA 3D9UA 4MTZA 4KMNA 1NW9A 3GTAA 4J3YA 5C84A 4A0NA 3EYLA 1JD6A 5C7CA 3UIIA 4J48A 1I3OE 4KJUA 1QBHA 1F9XA 4KMPA 3UW4A 4HY0A 2QFAA 3UEFA 4EB9A 5C7BA 3CM2A 3F7GA 3UIJA 3CLXA 1SDZA 1SE0A 5C83A 3UEEA 3MUPA 3UEHA 5C0LA 3UW5A 4WVUA 1G3FA 2RAWA 4MU7A 5C7AA 1XOXA 4EC4A 1OXNA 3SIQA 3M0AD 4OXCA 4KJVA 3HL5A 4J44A 2POIA 3UECA 2VM5A 1OY7A 1Q4QA 4MTIA 4J46A 2I3IA 3D9TA 1JD4A 3T6PA 4LGEA 3M0DD 4HY4A 3F7IA 3UEGA 5C0KA 4WVSA 1TFQA 5C3KA 3UIGA 1OXQA 5C7DA 3M1DA 2OPYA 3SIPE
chains in the Genus database with same CATH superfamily
2QRAA 3UEIA 4HY5A 1JD5A 1XB0A 4A0IA 3F7HA 3GT9A 4J47A 3OZ1A 3UIHA 5C3HA 1M4MA 2POPB 1TW6A 1C9QA 2UVLA 4J45A 4LGUA 1XB1A 2RAXA 1TFTA 1G73C 1F3HA 3CM7A 2I3HA 2OPZA 2JK7A 3UIKA 4A0JA 2VSLA 1E31A 3G76A 3UEDA 4WVTA 3D9UA 4MTZA 4KMNA 1NW9A 3GTAA 4J3YA 5C84A 4A0NA 3EYLA 1JD6A 5C7CA 3UIIA 4J48A 1I3OE 4KJUA 1QBHA 1F9XA 4KMPA 3UW4A 4HY0A 2QFAA 3UEFA 4EB9A 5C7BA 3CM2A 3F7GA 3UIJA 3CLXA 1SDZA 1SE0A 5C83A 3UEEA 3MUPA 3UEHA 5C0LA 3UW5A 4WVUA 1G3FA 2RAWA 4MU7A 5C7AA 1XOXA 4EC4A 1OXNA 3SIQA 3M0AD 4OXCA 4KJVA 3HL5A 4J44A 2POIA 3UECA 2VM5A 1OY7A 1Q4QA 4MTIA 4J46A 2I3IA 3D9TA 1JD4A 3T6PA 4LGEA 3M0DD 4HY4A 3F7IA 3UEGA 5C0KA 4WVSA 1TFQA 5C3KA 3UIGA 1OXQA 5C7DA 3M1DA 2OPYA 3SIPE
chains in the Genus database with same CATH topology
2QRAA 3UEIA 4HY5A 1JD5A 1XB0A 4A0IA 3F7HA 3GT9A 4J47A 3OZ1A 3UIHA 5C3HA 1M4MA 2POPB 1TW6A 1C9QA 2UVLA 4J45A 4LGUA 1XB1A 2RAXA 1TFTA 1G73C 1F3HA 3CM7A 2I3HA 2OPZA 2JK7A 3UIKA 4A0JA 2VSLA 1E31A 3G76A 3UEDA 4WVTA 3D9UA 4MTZA 4KMNA 1NW9A 3GTAA 4J3YA 5C84A 4A0NA 3EYLA 1JD6A 5C7CA 3UIIA 4J48A 1I3OE 4KJUA 1QBHA 1F9XA 4KMPA 3UW4A 4HY0A 2QFAA 3UEFA 4EB9A 5C7BA 3CM2A 3F7GA 3UIJA 3CLXA 1SDZA 1SE0A 5C83A 3UEEA 3MUPA 3UEHA 5C0LA 3UW5A 4WVUA 1G3FA 2RAWA 4MU7A 5C7AA 1XOXA 4EC4A 1OXNA 3SIQA 3M0AD 4OXCA 4KJVA 3HL5A 4J44A 2POIA 3UECA 2VM5A 1OY7A 1Q4QA 4MTIA 4J46A 2I3IA 3D9TA 1JD4A 3T6PA 4LGEA 3M0DD 4HY4A 3F7IA 3UEGA 5C0KA 4WVSA 1TFQA 5C3KA 3UIGA 1OXQA 5C7DA 3M1DA 2OPYA 3SIPE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QRA A;  3UEI A;  4HY5 A;  1JD5 A;  1XB0 A;  4A0I A;  3F7H A;  3GT9 A;  4J47 A;  3OZ1 A;  3UIH A;  5C3H A;  1M4M A;  2POP B;  1TW6 A;  1C9Q A;  2UVL A;  4J45 A;  4LGU A;  1XB1 A;  2RAX A;  1TFT A;  1G73 C;  1F3H A;  3CM7 A;  2I3H A;  2OPZ A;  2JK7 A;  3UIK A;  4A0J A;  2VSL A;  1E31 A;  3G76 A;  3UED A;  4WVT A;  3D9U A;  4MTZ A;  4KMN A;  1NW9 A;  3GTA A;  4J3Y A;  5C84 A;  4A0N A;  3EYL A;  1JD6 A;  5C7C A;  3UII A;  4J48 A;  1I3O E;  4KJU A;  1QBH A;  1F9X A;  4KMP A;  3UW4 A;  4HY0 A;  2QFA A;  3UEF A;  4EB9 A;  5C7B A;  3CM2 A;  3F7G A;  3UIJ A;  3CLX A;  1SDZ A;  1SE0 A;  5C83 A;  3UEE A;  3MUP A;  3UEH A;  5C0L A;  3UW5 A;  4WVU A;  1G3F A;  2RAW A;  4MU7 A;  5C7A A;  1XOX A;  4EC4 A;  1OXN A;  3SIQ A;  3M0A D;  4OXC A;  4KJV A;  3HL5 A;  4J44 A;  2POI A;  3UEC A;  2VM5 A;  1OY7 A;  1Q4Q A;  4MTI A;  4J46 A;  2I3I A;  3D9T A;  1JD4 A;  3T6P A;  4LGE A;  3M0D D;  4HY4 A;  3F7I A;  3UEG A;  5C0K A;  4WVS A;  1TFQ A;  5C3K A;  3UIG A;  1OXQ A;  5C7D A;  3M1D A;  2OPY A;  3SIP E; 
#chains in the Genus database with same CATH topology
 2QRA A;  3UEI A;  4HY5 A;  1JD5 A;  1XB0 A;  4A0I A;  3F7H A;  3GT9 A;  4J47 A;  3OZ1 A;  3UIH A;  5C3H A;  1M4M A;  2POP B;  1TW6 A;  1C9Q A;  2UVL A;  4J45 A;  4LGU A;  1XB1 A;  2RAX A;  1TFT A;  1G73 C;  1F3H A;  3CM7 A;  2I3H A;  2OPZ A;  2JK7 A;  3UIK A;  4A0J A;  2VSL A;  1E31 A;  3G76 A;  3UED A;  4WVT A;  3D9U A;  4MTZ A;  4KMN A;  1NW9 A;  3GTA A;  4J3Y A;  5C84 A;  4A0N A;  3EYL A;  1JD6 A;  5C7C A;  3UII A;  4J48 A;  1I3O E;  4KJU A;  1QBH A;  1F9X A;  4KMP A;  3UW4 A;  4HY0 A;  2QFA A;  3UEF A;  4EB9 A;  5C7B A;  3CM2 A;  3F7G A;  3UIJ A;  3CLX A;  1SDZ A;  1SE0 A;  5C83 A;  3UEE A;  3MUP A;  3UEH A;  5C0L A;  3UW5 A;  4WVU A;  1G3F A;  2RAW A;  4MU7 A;  5C7A A;  1XOX A;  4EC4 A;  1OXN A;  3SIQ A;  3M0A D;  4OXC A;  4KJV A;  3HL5 A;  4J44 A;  2POI A;  3UEC A;  2VM5 A;  1OY7 A;  1Q4Q A;  4MTI A;  4J46 A;  2I3I A;  3D9T A;  1JD4 A;  3T6P A;  4LGE A;  3M0D D;  4HY4 A;  3F7I A;  3UEG A;  5C0K A;  4WVS A;  1TFQ A;  5C3K A;  3UIG A;  1OXQ A;  5C7D A;  3M1D A;  2OPY A;  3SIP E; 
#chains in the Genus database with same CATH homology
 2QRA A;  3UEI A;  4HY5 A;  1JD5 A;  1XB0 A;  4A0I A;  3F7H A;  3GT9 A;  4J47 A;  3OZ1 A;  3UIH A;  5C3H A;  1M4M A;  2POP B;  1TW6 A;  1C9Q A;  2UVL A;  4J45 A;  4LGU A;  1XB1 A;  2RAX A;  1TFT A;  1G73 C;  1F3H A;  3CM7 A;  2I3H A;  2OPZ A;  2JK7 A;  3UIK A;  4A0J A;  2VSL A;  1E31 A;  3G76 A;  3UED A;  4WVT A;  3D9U A;  4MTZ A;  4KMN A;  1NW9 A;  3GTA A;  4J3Y A;  5C84 A;  4A0N A;  3EYL A;  1JD6 A;  5C7C A;  3UII A;  4J48 A;  1I3O E;  4KJU A;  1QBH A;  1F9X A;  4KMP A;  3UW4 A;  4HY0 A;  2QFA A;  3UEF A;  4EB9 A;  5C7B A;  3CM2 A;  3F7G A;  3UIJ A;  3CLX A;  1SDZ A;  1SE0 A;  5C83 A;  3UEE A;  3MUP A;  3UEH A;  5C0L A;  3UW5 A;  4WVU A;  1G3F A;  2RAW A;  4MU7 A;  5C7A A;  1XOX A;  4EC4 A;  1OXN A;  3SIQ A;  3M0A D;  4OXC A;  4KJV A;  3HL5 A;  4J44 A;  2POI A;  3UEC A;  2VM5 A;  1OY7 A;  1Q4Q A;  4MTI A;  4J46 A;  2I3I A;  3D9T A;  1JD4 A;  3T6P A;  4LGE A;  3M0D D;  4HY4 A;  3F7I A;  3UEG A;  5C0K A;  4WVS A;  1TFQ A;  5C3K A;  3UIG A;  1OXQ A;  5C7D A;  3M1D A;  2OPY A;  3SIP E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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