2ARFA

Solution structure of the wilson atpase n-domain in the presence of atp
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
165
structure length
165
Chain Sequence
AGHMVPRVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of the N-domain of Wilson disease protein: Distinct nucleotide-binding environment and effects of disease mutations
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords WILSON DISEASE ATPASE
total genus 26
structure length 165
sequence length 165
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2005-08-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1110.10 Alpha Beta 3-Layer(aba) Sandwich Calcium-transporting ATPase, cytoplasmic domain N Calcium-transporting ATPase, cytoplasmic domain N 2arfA00
3GWIA 2YJ6A 4J2TA 1WPGA 3W5CA 2YJ3A 3NALA 3W5AA 2YJ4A 2YFYA 1Q3IA 3NAMA 4YCNA 5AW5A 4H1WA 3B9RA 3KDPA 3AR3A 4RETA 5AVXA 3B8EA 5AVWA 2C8KA 3N8GA 3AR7A 4UMVA 4KYTA 3B9BA 3AR6A 4BEVA 1T5TA 2C9MA 2ZBFA 3FPBA 2ZBGA 5AVZA 5AW6A 1IWOA 3SKXA 5AW9A 2ZXEA 2B8EA 5AW7A 2ARFA 3AR4A 1T5SA 5AW0A 3A1EA 2OA0A 2EATA 5A3RA 1SU4A 3NANA 3A1CA 1VFPA 5A3QA 5AW3A 2IYEA 3AR9A 3BA6A 3A1DA 5AW8A 2A29A 1SVJA 4BEWA 4XOUA 3WGVA 5AW2A 2C88A 3A3YA 4NABA 5AVVA 3N5KA 5AVUA 5AW1A 2KMXA 5AVYA 3J7TA 3TLMA 2EARA 5AW4A 4BBJA 3WGUA 2C8LA 3AR8A 5AVQA 5AVRA 3W5DA 4YCMA 3SKYA 4BYGA 5AVSA 2ZBDA 4HYTA 3FPSA 2O9JA 2A00A 1MO7A 4RESA 1U7QA 3W5BA 2KMVA 2ZBEA 4UU0A 2DQSA 2AGVA 3FGOA 4Y3UA 4UU1A 4YCLA 3AR2A 1MO8A 2YJ5A 3RFUA 1XP5A 2BY4A 5A3SA 2EAUA 5AVTA 4XE5A 3AR5A
chains in the Genus database with same CATH superfamily
3GWIA 2YJ6A 4J2TA 1WPGA 3W5CA 2YJ3A 3NALA 3W5AA 2YJ4A 2YFYA 1Q3IA 3NAMA 4YCNA 5AW5A 4H1WA 3B9RA 3KDPA 3AR3A 4RETA 5AVXA 3B8EA 5AVWA 2C8KA 3N8GA 3AR7A 4UMVA 4KYTA 3B9BA 3AR6A 4BEVA 1T5TA 2C9MA 2ZBFA 3FPBA 2ZBGA 5AVZA 5AW6A 1IWOA 3SKXA 5AW9A 2ZXEA 2B8EA 5AW7A 2ARFA 3AR4A 1T5SA 5AW0A 3A1EA 2OA0A 2EATA 5A3RA 1SU4A 3NANA 3A1CA 1VFPA 5A3QA 5AW3A 2IYEA 3AR9A 3BA6A 3A1DA 5AW8A 2A29A 1SVJA 4BEWA 4XOUA 3WGVA 5AW2A 2C88A 3A3YA 4NABA 5AVVA 3N5KA 5AVUA 5AW1A 2KMXA 5AVYA 3J7TA 3TLMA 2EARA 5AW4A 4BBJA 3WGUA 2C8LA 3AR8A 5AVQA 5AVRA 3W5DA 4YCMA 3SKYA 4BYGA 5AVSA 2ZBDA 4HYTA 3FPSA 2O9JA 2A00A 1MO7A 4RESA 1U7QA 3W5BA 2KMVA 2ZBEA 4UU0A 2DQSA 2AGVA 3FGOA 4Y3UA 4UU1A 4YCLA 3AR2A 1MO8A 2YJ5A 3RFUA 1XP5A 2BY4A 5A3SA 2EAUA 5AVTA 4XE5A 3AR5A
chains in the Genus database with same CATH topology
3GWIA 2YJ6A 4J2TA 1WPGA 3W5CA 2YJ3A 3NALA 3W5AA 2YJ4A 2YFYA 1Q3IA 3NAMA 4YCNA 5AW5A 4H1WA 3B9RA 3KDPA 3AR3A 4RETA 5AVXA 3B8EA 5AVWA 2C8KA 3N8GA 3AR7A 4UMVA 4KYTA 3B9BA 3AR6A 4BEVA 1T5TA 2C9MA 2ZBFA 3FPBA 2ZBGA 5AVZA 5AW6A 1IWOA 3SKXA 5AW9A 2ZXEA 2B8EA 5AW7A 2ARFA 3AR4A 1T5SA 5AW0A 3A1EA 2OA0A 2EATA 5A3RA 1SU4A 3NANA 3A1CA 1VFPA 5A3QA 5AW3A 2IYEA 3AR9A 3BA6A 3A1DA 5AW8A 2A29A 1SVJA 4BEWA 4XOUA 3WGVA 5AW2A 2C88A 3A3YA 4NABA 5AVVA 3N5KA 5AVUA 5AW1A 2KMXA 5AVYA 3J7TA 3TLMA 2EARA 5AW4A 4BBJA 3WGUA 2C8LA 3AR8A 5AVQA 5AVRA 3W5DA 4YCMA 3SKYA 4BYGA 5AVSA 2ZBDA 4HYTA 3FPSA 2O9JA 2A00A 1MO7A 4RESA 1U7QA 3W5BA 2KMVA 2ZBEA 4UU0A 2DQSA 2AGVA 3FGOA 4Y3UA 4UU1A 4YCLA 3AR2A 1MO8A 2YJ5A 3RFUA 1XP5A 2BY4A 5A3SA 2EAUA 5AVTA 4XE5A 3AR5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GWI A;  2YJ6 A;  4J2T A;  1WPG A;  3W5C A;  2YJ3 A;  3NAL A;  3W5A A;  2YJ4 A;  2YFY A;  1Q3I A;  3NAM A;  4YCN A;  5AW5 A;  4H1W A;  3B9R A;  3KDP A;  3AR3 A;  4RET A;  5AVX A;  3B8E A;  5AVW A;  2C8K A;  3N8G A;  3AR7 A;  4UMV A;  4KYT A;  3B9B A;  3AR6 A;  4BEV A;  1T5T A;  2C9M A;  2ZBF A;  3FPB A;  2ZBG A;  5AVZ A;  5AW6 A;  1IWO A;  3SKX A;  5AW9 A;  2ZXE A;  2B8E A;  5AW7 A;  2ARF A;  3AR4 A;  1T5S A;  5AW0 A;  3A1E A;  2OA0 A;  2EAT A;  5A3R A;  1SU4 A;  3NAN A;  3A1C A;  1VFP A;  5A3Q A;  5AW3 A;  2IYE A;  3AR9 A;  3BA6 A;  3A1D A;  5AW8 A;  2A29 A;  1SVJ A;  4BEW A;  4XOU A;  3WGV A;  5AW2 A;  2C88 A;  3A3Y A;  4NAB A;  5AVV A;  3N5K A;  5AVU A;  5AW1 A;  2KMX A;  5AVY A;  3J7T A;  3TLM A;  2EAR A;  5AW4 A;  4BBJ A;  3WGU A;  2C8L A;  3AR8 A;  5AVQ A;  5AVR A;  3W5D A;  4YCM A;  3SKY A;  4BYG A;  5AVS A;  2ZBD A;  4HYT A;  3FPS A;  2O9J A;  2A00 A;  1MO7 A;  4RES A;  1U7Q A;  3W5B A;  2KMV A;  2ZBE A;  4UU0 A;  2DQS A;  2AGV A;  3FGO A;  4Y3U A;  4UU1 A;  4YCL A;  3AR2 A;  1MO8 A;  2YJ5 A;  3RFU A;  1XP5 A;  2BY4 A;  5A3S A;  2EAU A;  5AVT A;  4XE5 A;  3AR5 A; 
#chains in the Genus database with same CATH topology
 3GWI A;  2YJ6 A;  4J2T A;  1WPG A;  3W5C A;  2YJ3 A;  3NAL A;  3W5A A;  2YJ4 A;  2YFY A;  1Q3I A;  3NAM A;  4YCN A;  5AW5 A;  4H1W A;  3B9R A;  3KDP A;  3AR3 A;  4RET A;  5AVX A;  3B8E A;  5AVW A;  2C8K A;  3N8G A;  3AR7 A;  4UMV A;  4KYT A;  3B9B A;  3AR6 A;  4BEV A;  1T5T A;  2C9M A;  2ZBF A;  3FPB A;  2ZBG A;  5AVZ A;  5AW6 A;  1IWO A;  3SKX A;  5AW9 A;  2ZXE A;  2B8E A;  5AW7 A;  2ARF A;  3AR4 A;  1T5S A;  5AW0 A;  3A1E A;  2OA0 A;  2EAT A;  5A3R A;  1SU4 A;  3NAN A;  3A1C A;  1VFP A;  5A3Q A;  5AW3 A;  2IYE A;  3AR9 A;  3BA6 A;  3A1D A;  5AW8 A;  2A29 A;  1SVJ A;  4BEW A;  4XOU A;  3WGV A;  5AW2 A;  2C88 A;  3A3Y A;  4NAB A;  5AVV A;  3N5K A;  5AVU A;  5AW1 A;  2KMX A;  5AVY A;  3J7T A;  3TLM A;  2EAR A;  5AW4 A;  4BBJ A;  3WGU A;  2C8L A;  3AR8 A;  5AVQ A;  5AVR A;  3W5D A;  4YCM A;  3SKY A;  4BYG A;  5AVS A;  2ZBD A;  4HYT A;  3FPS A;  2O9J A;  2A00 A;  1MO7 A;  4RES A;  1U7Q A;  3W5B A;  2KMV A;  2ZBE A;  4UU0 A;  2DQS A;  2AGV A;  3FGO A;  4Y3U A;  4UU1 A;  4YCL A;  3AR2 A;  1MO8 A;  2YJ5 A;  3RFU A;  1XP5 A;  2BY4 A;  5A3S A;  2EAU A;  5AVT A;  4XE5 A;  3AR5 A; 
#chains in the Genus database with same CATH homology
 3GWI A;  2YJ6 A;  4J2T A;  1WPG A;  3W5C A;  2YJ3 A;  3NAL A;  3W5A A;  2YJ4 A;  2YFY A;  1Q3I A;  3NAM A;  4YCN A;  5AW5 A;  4H1W A;  3B9R A;  3KDP A;  3AR3 A;  4RET A;  5AVX A;  3B8E A;  5AVW A;  2C8K A;  3N8G A;  3AR7 A;  4UMV A;  4KYT A;  3B9B A;  3AR6 A;  4BEV A;  1T5T A;  2C9M A;  2ZBF A;  3FPB A;  2ZBG A;  5AVZ A;  5AW6 A;  1IWO A;  3SKX A;  5AW9 A;  2ZXE A;  2B8E A;  5AW7 A;  2ARF A;  3AR4 A;  1T5S A;  5AW0 A;  3A1E A;  2OA0 A;  2EAT A;  5A3R A;  1SU4 A;  3NAN A;  3A1C A;  1VFP A;  5A3Q A;  5AW3 A;  2IYE A;  3AR9 A;  3BA6 A;  3A1D A;  5AW8 A;  2A29 A;  1SVJ A;  4BEW A;  4XOU A;  3WGV A;  5AW2 A;  2C88 A;  3A3Y A;  4NAB A;  5AVV A;  3N5K A;  5AVU A;  5AW1 A;  2KMX A;  5AVY A;  3J7T A;  3TLM A;  2EAR A;  5AW4 A;  4BBJ A;  3WGU A;  2C8L A;  3AR8 A;  5AVQ A;  5AVR A;  3W5D A;  4YCM A;  3SKY A;  4BYG A;  5AVS A;  2ZBD A;  4HYT A;  3FPS A;  2O9J A;  2A00 A;  1MO7 A;  4RES A;  1U7Q A;  3W5B A;  2KMV A;  2ZBE A;  4UU0 A;  2DQS A;  2AGV A;  3FGO A;  4Y3U A;  4UU1 A;  4YCL A;  3AR2 A;  1MO8 A;  2YJ5 A;  3RFU A;  1XP5 A;  2BY4 A;  5A3S A;  2EAU A;  5AVT A;  4XE5 A;  3AR5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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