2KMVA

Solution structure of the nucleotide binding domain of the human menkes protein in the atp-free form
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
185
structure length
185
Chain Sequence
SFTMHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Copper-transporting ATPase 1
total genus 35
structure length 185
sequence length 185
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2009-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1110.10 Alpha Beta 3-Layer(aba) Sandwich Calcium-transporting ATPase, cytoplasmic domain N Calcium-transporting ATPase, cytoplasmic domain N 2kmvA01
3AR8A 2C9MA 4BBJA 2ZBFA 3FPBA 3NANA 4UMVA 3A1CA 2ZBEA 3FGOA 3SKYA 4YCMA 2O9JA 1Q3IA 3FPSA 2YJ5A 3KDPA 4RETA 3GWIA 3W5AA 1SU4A 3W5BA 5AVUA 5AW1A 4XE5A 3TLMA 1SVJA 4BEWA 3A1EA 5AVQA 3AR7A 4YCLA 3WGVA 3AR5A 4NABA 2YJ3A 2B8EA 2OA0A 5A3RA 4H1WA 5AVVA 1IWOA 3AR9A 3AR6A 5AW5A 2EARA 2KMXA 1WPGA 5A3SA 3SKXA 2ZBGA 5AW0A 2KMVA 2IYEA 4BYGA 1XP5A 2YFYA 3B9BA 5AVTA 3N8GA 2A00A 4UU1A 3A3YA 3N5KA 2C8LA 3WGUA 2C8KA 2AGVA 1T5TA 3RFUA 5AW6A 5AW4A 2YJ6A 2A29A 5AW8A 5AVXA 5A3QA 5AVSA 5AVWA 3W5DA 4J2TA 1VFPA 5AVYA 1MO8A 5AW2A 4BEVA 3B9RA 4HYTA 5AW9A 2ZBDA 2ARFA 3BA6A 4UU0A 1U7QA 2C88A 3NAMA 4YCNA 1MO7A 2EATA 2YJ4A 3AR2A 4XOUA 2BY4A 3J7TA 3W5CA 5AW7A 5AW3A 2DQSA 5AVRA 1T5SA 2EAUA 3B8EA 2ZXEA 3NALA 5AVZA 3A1DA 3AR4A 4KYTA 4Y3UA 3AR3A 4RESA
chains in the Genus database with same CATH superfamily
3AR8A 2C9MA 4BBJA 2ZBFA 3FPBA 3NANA 4UMVA 3A1CA 2ZBEA 3FGOA 3SKYA 4YCMA 2O9JA 1Q3IA 3FPSA 2YJ5A 3KDPA 4RETA 3GWIA 3W5AA 1SU4A 3W5BA 5AVUA 5AW1A 4XE5A 3TLMA 1SVJA 4BEWA 3A1EA 5AVQA 3AR7A 4YCLA 3WGVA 3AR5A 4NABA 2YJ3A 2B8EA 2OA0A 5A3RA 4H1WA 5AVVA 1IWOA 3AR9A 3AR6A 5AW5A 2EARA 2KMXA 1WPGA 5A3SA 3SKXA 2ZBGA 5AW0A 2KMVA 2IYEA 4BYGA 1XP5A 2YFYA 3B9BA 5AVTA 3N8GA 2A00A 4UU1A 3A3YA 3N5KA 2C8LA 3WGUA 2C8KA 2AGVA 1T5TA 3RFUA 5AW6A 5AW4A 2YJ6A 2A29A 5AW8A 5AVXA 5A3QA 5AVSA 5AVWA 3W5DA 4J2TA 1VFPA 5AVYA 1MO8A 5AW2A 4BEVA 3B9RA 4HYTA 5AW9A 2ZBDA 2ARFA 3BA6A 4UU0A 1U7QA 2C88A 3NAMA 4YCNA 1MO7A 2EATA 2YJ4A 3AR2A 4XOUA 2BY4A 3J7TA 3W5CA 5AW7A 5AW3A 2DQSA 5AVRA 1T5SA 2EAUA 3B8EA 2ZXEA 3NALA 5AVZA 3A1DA 3AR4A 4KYTA 4Y3UA 3AR3A 4RESA
chains in the Genus database with same CATH topology
3AR8A 2C9MA 4BBJA 2ZBFA 3FPBA 3NANA 4UMVA 3A1CA 2ZBEA 3FGOA 3SKYA 4YCMA 2O9JA 1Q3IA 3FPSA 2YJ5A 3KDPA 4RETA 3GWIA 3W5AA 1SU4A 3W5BA 5AVUA 5AW1A 4XE5A 3TLMA 1SVJA 4BEWA 3A1EA 5AVQA 3AR7A 4YCLA 3WGVA 3AR5A 4NABA 2YJ3A 2B8EA 2OA0A 5A3RA 4H1WA 5AVVA 1IWOA 3AR9A 3AR6A 5AW5A 2EARA 2KMXA 1WPGA 5A3SA 3SKXA 2ZBGA 5AW0A 2KMVA 2IYEA 4BYGA 1XP5A 2YFYA 3B9BA 5AVTA 3N8GA 2A00A 4UU1A 3A3YA 3N5KA 2C8LA 3WGUA 2C8KA 2AGVA 1T5TA 3RFUA 5AW6A 5AW4A 2YJ6A 2A29A 5AW8A 5AVXA 5A3QA 5AVSA 5AVWA 3W5DA 4J2TA 1VFPA 5AVYA 1MO8A 5AW2A 4BEVA 3B9RA 4HYTA 5AW9A 2ZBDA 2ARFA 3BA6A 4UU0A 1U7QA 2C88A 3NAMA 4YCNA 1MO7A 2EATA 2YJ4A 3AR2A 4XOUA 2BY4A 3J7TA 3W5CA 5AW7A 5AW3A 2DQSA 5AVRA 1T5SA 2EAUA 3B8EA 2ZXEA 3NALA 5AVZA 3A1DA 3AR4A 4KYTA 4Y3UA 3AR3A 4RESA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AR8 A;  2C9M A;  4BBJ A;  2ZBF A;  3FPB A;  3NAN A;  4UMV A;  3A1C A;  2ZBE A;  3FGO A;  3SKY A;  4YCM A;  2O9J A;  1Q3I A;  3FPS A;  2YJ5 A;  3KDP A;  4RET A;  3GWI A;  3W5A A;  1SU4 A;  3W5B A;  5AVU A;  5AW1 A;  4XE5 A;  3TLM A;  1SVJ A;  4BEW A;  3A1E A;  5AVQ A;  3AR7 A;  4YCL A;  3WGV A;  3AR5 A;  4NAB A;  2YJ3 A;  2B8E A;  2OA0 A;  5A3R A;  4H1W A;  5AVV A;  1IWO A;  3AR9 A;  3AR6 A;  5AW5 A;  2EAR A;  2KMX A;  1WPG A;  5A3S A;  3SKX A;  2ZBG A;  5AW0 A;  2KMV A;  2IYE A;  4BYG A;  1XP5 A;  2YFY A;  3B9B A;  5AVT A;  3N8G A;  2A00 A;  4UU1 A;  3A3Y A;  3N5K A;  2C8L A;  3WGU A;  2C8K A;  2AGV A;  1T5T A;  3RFU A;  5AW6 A;  5AW4 A;  2YJ6 A;  2A29 A;  5AW8 A;  5AVX A;  5A3Q A;  5AVS A;  5AVW A;  3W5D A;  4J2T A;  1VFP A;  5AVY A;  1MO8 A;  5AW2 A;  4BEV A;  3B9R A;  4HYT A;  5AW9 A;  2ZBD A;  2ARF A;  3BA6 A;  4UU0 A;  1U7Q A;  2C88 A;  3NAM A;  4YCN A;  1MO7 A;  2EAT A;  2YJ4 A;  3AR2 A;  4XOU A;  2BY4 A;  3J7T A;  3W5C A;  5AW7 A;  5AW3 A;  2DQS A;  5AVR A;  1T5S A;  2EAU A;  3B8E A;  2ZXE A;  3NAL A;  5AVZ A;  3A1D A;  3AR4 A;  4KYT A;  4Y3U A;  3AR3 A;  4RES A; 
#chains in the Genus database with same CATH topology
 3AR8 A;  2C9M A;  4BBJ A;  2ZBF A;  3FPB A;  3NAN A;  4UMV A;  3A1C A;  2ZBE A;  3FGO A;  3SKY A;  4YCM A;  2O9J A;  1Q3I A;  3FPS A;  2YJ5 A;  3KDP A;  4RET A;  3GWI A;  3W5A A;  1SU4 A;  3W5B A;  5AVU A;  5AW1 A;  4XE5 A;  3TLM A;  1SVJ A;  4BEW A;  3A1E A;  5AVQ A;  3AR7 A;  4YCL A;  3WGV A;  3AR5 A;  4NAB A;  2YJ3 A;  2B8E A;  2OA0 A;  5A3R A;  4H1W A;  5AVV A;  1IWO A;  3AR9 A;  3AR6 A;  5AW5 A;  2EAR A;  2KMX A;  1WPG A;  5A3S A;  3SKX A;  2ZBG A;  5AW0 A;  2KMV A;  2IYE A;  4BYG A;  1XP5 A;  2YFY A;  3B9B A;  5AVT A;  3N8G A;  2A00 A;  4UU1 A;  3A3Y A;  3N5K A;  2C8L A;  3WGU A;  2C8K A;  2AGV A;  1T5T A;  3RFU A;  5AW6 A;  5AW4 A;  2YJ6 A;  2A29 A;  5AW8 A;  5AVX A;  5A3Q A;  5AVS A;  5AVW A;  3W5D A;  4J2T A;  1VFP A;  5AVY A;  1MO8 A;  5AW2 A;  4BEV A;  3B9R A;  4HYT A;  5AW9 A;  2ZBD A;  2ARF A;  3BA6 A;  4UU0 A;  1U7Q A;  2C88 A;  3NAM A;  4YCN A;  1MO7 A;  2EAT A;  2YJ4 A;  3AR2 A;  4XOU A;  2BY4 A;  3J7T A;  3W5C A;  5AW7 A;  5AW3 A;  2DQS A;  5AVR A;  1T5S A;  2EAU A;  3B8E A;  2ZXE A;  3NAL A;  5AVZ A;  3A1D A;  3AR4 A;  4KYT A;  4Y3U A;  3AR3 A;  4RES A; 
#chains in the Genus database with same CATH homology
 3AR8 A;  2C9M A;  4BBJ A;  2ZBF A;  3FPB A;  3NAN A;  4UMV A;  3A1C A;  2ZBE A;  3FGO A;  3SKY A;  4YCM A;  2O9J A;  1Q3I A;  3FPS A;  2YJ5 A;  3KDP A;  4RET A;  3GWI A;  3W5A A;  1SU4 A;  3W5B A;  5AVU A;  5AW1 A;  4XE5 A;  3TLM A;  1SVJ A;  4BEW A;  3A1E A;  5AVQ A;  3AR7 A;  4YCL A;  3WGV A;  3AR5 A;  4NAB A;  2YJ3 A;  2B8E A;  2OA0 A;  5A3R A;  4H1W A;  5AVV A;  1IWO A;  3AR9 A;  3AR6 A;  5AW5 A;  2EAR A;  2KMX A;  1WPG A;  5A3S A;  3SKX A;  2ZBG A;  5AW0 A;  2KMV A;  2IYE A;  4BYG A;  1XP5 A;  2YFY A;  3B9B A;  5AVT A;  3N8G A;  2A00 A;  4UU1 A;  3A3Y A;  3N5K A;  2C8L A;  3WGU A;  2C8K A;  2AGV A;  1T5T A;  3RFU A;  5AW6 A;  5AW4 A;  2YJ6 A;  2A29 A;  5AW8 A;  5AVX A;  5A3Q A;  5AVS A;  5AVW A;  3W5D A;  4J2T A;  1VFP A;  5AVY A;  1MO8 A;  5AW2 A;  4BEV A;  3B9R A;  4HYT A;  5AW9 A;  2ZBD A;  2ARF A;  3BA6 A;  4UU0 A;  1U7Q A;  2C88 A;  3NAM A;  4YCN A;  1MO7 A;  2EAT A;  2YJ4 A;  3AR2 A;  4XOU A;  2BY4 A;  3J7T A;  3W5C A;  5AW7 A;  5AW3 A;  2DQS A;  5AVR A;  1T5S A;  2EAU A;  3B8E A;  2ZXE A;  3NAL A;  5AVZ A;  3A1D A;  3AR4 A;  4KYT A;  4Y3U A;  3AR3 A;  4RES A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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