2KMVA

Solution structure of the nucleotide binding domain of the human menkes protein in the atp-free form
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
185
structure length
185
Chain Sequence
SFTMHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Copper-transporting ATPase 1
total genus 35
structure length 185
sequence length 185
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2009-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1110.10 Alpha Beta 3-Layer(aba) Sandwich Calcium-transporting ATPase, cytoplasmic domain N Calcium-transporting ATPase, cytoplasmic domain N 2kmvA01
1MO7A 3N8GA 5AVQA 3SKXA 2KMVA 3FGOA 4HYTA 3W5DA 3NALA 4YCNA 3AR2A 5AVZA 2A00A 3NANA 5AVTA 3KDPA 4BEWA 5AW2A 2EAUA 2DQSA 3B8EA 5AW3A 3AR4A 5AW0A 2OA0A 2BY4A 3W5AA 2B8EA 2A29A 1Q3IA 4RESA 3A1CA 2IYEA 4XOUA 2ZXEA 4YCLA 4UMVA 4UU1A 5A3RA 3AR6A 1XP5A 1U7QA 3NAMA 5AVWA 3RFUA 3B9BA 3FPBA 5A3SA 4UU0A 2YFYA 3A3YA 3TLMA 5AVSA 5AW8A 4Y3UA 1SVJA 3N5KA 3W5CA 2C8LA 2KMXA 1MO8A 3FPSA 2ARFA 2O9JA 4XE5A 2YJ5A 3A1EA 5AW9A 1T5SA 5AW4A 5AW5A 2ZBEA 5AVUA 5AVVA 5AVYA 2C8KA 3W5BA 2YJ4A 4BEVA 1SU4A 4BYGA 2AGVA 5AW7A 1WPGA 4BBJA 3AR3A 2EATA 5AW6A 3AR8A 3BA6A 2ZBFA 3B9RA 5AW1A 4NABA 4YCMA 2YJ6A 4H1WA 3A1DA 4KYTA 2ZBGA 2EARA 3SKYA 5AVRA 2YJ3A 3WGUA 2ZBDA 5AVXA 1T5TA 4RETA 1VFPA 3AR9A 2C9MA 3WGVA 2C88A 3GWIA 3AR5A 3J7TA 1IWOA 5A3QA 4J2TA 3AR7A
chains in the Genus database with same CATH superfamily
1MO7A 3N8GA 5AVQA 3SKXA 2KMVA 3FGOA 4HYTA 3W5DA 3NALA 4YCNA 3AR2A 5AVZA 2A00A 3NANA 5AVTA 3KDPA 4BEWA 5AW2A 2EAUA 2DQSA 3B8EA 5AW3A 3AR4A 5AW0A 2OA0A 2BY4A 3W5AA 2B8EA 2A29A 1Q3IA 4RESA 3A1CA 2IYEA 4XOUA 2ZXEA 4YCLA 4UMVA 4UU1A 5A3RA 3AR6A 1XP5A 1U7QA 3NAMA 5AVWA 3RFUA 3B9BA 3FPBA 5A3SA 4UU0A 2YFYA 3A3YA 3TLMA 5AVSA 5AW8A 4Y3UA 1SVJA 3N5KA 3W5CA 2C8LA 2KMXA 1MO8A 3FPSA 2ARFA 2O9JA 4XE5A 2YJ5A 3A1EA 5AW9A 1T5SA 5AW4A 5AW5A 2ZBEA 5AVUA 5AVVA 5AVYA 2C8KA 3W5BA 2YJ4A 4BEVA 1SU4A 4BYGA 2AGVA 5AW7A 1WPGA 4BBJA 3AR3A 2EATA 5AW6A 3AR8A 3BA6A 2ZBFA 3B9RA 5AW1A 4NABA 4YCMA 2YJ6A 4H1WA 3A1DA 4KYTA 2ZBGA 2EARA 3SKYA 5AVRA 2YJ3A 3WGUA 2ZBDA 5AVXA 1T5TA 4RETA 1VFPA 3AR9A 2C9MA 3WGVA 2C88A 3GWIA 3AR5A 3J7TA 1IWOA 5A3QA 4J2TA 3AR7A
chains in the Genus database with same CATH topology
1MO7A 3N8GA 5AVQA 3SKXA 2KMVA 3FGOA 4HYTA 3W5DA 3NALA 4YCNA 3AR2A 5AVZA 2A00A 3NANA 5AVTA 3KDPA 4BEWA 5AW2A 2EAUA 2DQSA 3B8EA 5AW3A 3AR4A 5AW0A 2OA0A 2BY4A 3W5AA 2B8EA 2A29A 1Q3IA 4RESA 3A1CA 2IYEA 4XOUA 2ZXEA 4YCLA 4UMVA 4UU1A 5A3RA 3AR6A 1XP5A 1U7QA 3NAMA 5AVWA 3RFUA 3B9BA 3FPBA 5A3SA 4UU0A 2YFYA 3A3YA 3TLMA 5AVSA 5AW8A 4Y3UA 1SVJA 3N5KA 3W5CA 2C8LA 2KMXA 1MO8A 3FPSA 2ARFA 2O9JA 4XE5A 2YJ5A 3A1EA 5AW9A 1T5SA 5AW4A 5AW5A 2ZBEA 5AVUA 5AVVA 5AVYA 2C8KA 3W5BA 2YJ4A 4BEVA 1SU4A 4BYGA 2AGVA 5AW7A 1WPGA 4BBJA 3AR3A 2EATA 5AW6A 3AR8A 3BA6A 2ZBFA 3B9RA 5AW1A 4NABA 4YCMA 2YJ6A 4H1WA 3A1DA 4KYTA 2ZBGA 2EARA 3SKYA 5AVRA 2YJ3A 3WGUA 2ZBDA 5AVXA 1T5TA 4RETA 1VFPA 3AR9A 2C9MA 3WGVA 2C88A 3GWIA 3AR5A 3J7TA 1IWOA 5A3QA 4J2TA 3AR7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MO7 A;  3N8G A;  5AVQ A;  3SKX A;  2KMV A;  3FGO A;  4HYT A;  3W5D A;  3NAL A;  4YCN A;  3AR2 A;  5AVZ A;  2A00 A;  3NAN A;  5AVT A;  3KDP A;  4BEW A;  5AW2 A;  2EAU A;  2DQS A;  3B8E A;  5AW3 A;  3AR4 A;  5AW0 A;  2OA0 A;  2BY4 A;  3W5A A;  2B8E A;  2A29 A;  1Q3I A;  4RES A;  3A1C A;  2IYE A;  4XOU A;  2ZXE A;  4YCL A;  4UMV A;  4UU1 A;  5A3R A;  3AR6 A;  1XP5 A;  1U7Q A;  3NAM A;  5AVW A;  3RFU A;  3B9B A;  3FPB A;  5A3S A;  4UU0 A;  2YFY A;  3A3Y A;  3TLM A;  5AVS A;  5AW8 A;  4Y3U A;  1SVJ A;  3N5K A;  3W5C A;  2C8L A;  2KMX A;  1MO8 A;  3FPS A;  2ARF A;  2O9J A;  4XE5 A;  2YJ5 A;  3A1E A;  5AW9 A;  1T5S A;  5AW4 A;  5AW5 A;  2ZBE A;  5AVU A;  5AVV A;  5AVY A;  2C8K A;  3W5B A;  2YJ4 A;  4BEV A;  1SU4 A;  4BYG A;  2AGV A;  5AW7 A;  1WPG A;  4BBJ A;  3AR3 A;  2EAT A;  5AW6 A;  3AR8 A;  3BA6 A;  2ZBF A;  3B9R A;  5AW1 A;  4NAB A;  4YCM A;  2YJ6 A;  4H1W A;  3A1D A;  4KYT A;  2ZBG A;  2EAR A;  3SKY A;  5AVR A;  2YJ3 A;  3WGU A;  2ZBD A;  5AVX A;  1T5T A;  4RET A;  1VFP A;  3AR9 A;  2C9M A;  3WGV A;  2C88 A;  3GWI A;  3AR5 A;  3J7T A;  1IWO A;  5A3Q A;  4J2T A;  3AR7 A; 
#chains in the Genus database with same CATH topology
 1MO7 A;  3N8G A;  5AVQ A;  3SKX A;  2KMV A;  3FGO A;  4HYT A;  3W5D A;  3NAL A;  4YCN A;  3AR2 A;  5AVZ A;  2A00 A;  3NAN A;  5AVT A;  3KDP A;  4BEW A;  5AW2 A;  2EAU A;  2DQS A;  3B8E A;  5AW3 A;  3AR4 A;  5AW0 A;  2OA0 A;  2BY4 A;  3W5A A;  2B8E A;  2A29 A;  1Q3I A;  4RES A;  3A1C A;  2IYE A;  4XOU A;  2ZXE A;  4YCL A;  4UMV A;  4UU1 A;  5A3R A;  3AR6 A;  1XP5 A;  1U7Q A;  3NAM A;  5AVW A;  3RFU A;  3B9B A;  3FPB A;  5A3S A;  4UU0 A;  2YFY A;  3A3Y A;  3TLM A;  5AVS A;  5AW8 A;  4Y3U A;  1SVJ A;  3N5K A;  3W5C A;  2C8L A;  2KMX A;  1MO8 A;  3FPS A;  2ARF A;  2O9J A;  4XE5 A;  2YJ5 A;  3A1E A;  5AW9 A;  1T5S A;  5AW4 A;  5AW5 A;  2ZBE A;  5AVU A;  5AVV A;  5AVY A;  2C8K A;  3W5B A;  2YJ4 A;  4BEV A;  1SU4 A;  4BYG A;  2AGV A;  5AW7 A;  1WPG A;  4BBJ A;  3AR3 A;  2EAT A;  5AW6 A;  3AR8 A;  3BA6 A;  2ZBF A;  3B9R A;  5AW1 A;  4NAB A;  4YCM A;  2YJ6 A;  4H1W A;  3A1D A;  4KYT A;  2ZBG A;  2EAR A;  3SKY A;  5AVR A;  2YJ3 A;  3WGU A;  2ZBD A;  5AVX A;  1T5T A;  4RET A;  1VFP A;  3AR9 A;  2C9M A;  3WGV A;  2C88 A;  3GWI A;  3AR5 A;  3J7T A;  1IWO A;  5A3Q A;  4J2T A;  3AR7 A; 
#chains in the Genus database with same CATH homology
 1MO7 A;  3N8G A;  5AVQ A;  3SKX A;  2KMV A;  3FGO A;  4HYT A;  3W5D A;  3NAL A;  4YCN A;  3AR2 A;  5AVZ A;  2A00 A;  3NAN A;  5AVT A;  3KDP A;  4BEW A;  5AW2 A;  2EAU A;  2DQS A;  3B8E A;  5AW3 A;  3AR4 A;  5AW0 A;  2OA0 A;  2BY4 A;  3W5A A;  2B8E A;  2A29 A;  1Q3I A;  4RES A;  3A1C A;  2IYE A;  4XOU A;  2ZXE A;  4YCL A;  4UMV A;  4UU1 A;  5A3R A;  3AR6 A;  1XP5 A;  1U7Q A;  3NAM A;  5AVW A;  3RFU A;  3B9B A;  3FPB A;  5A3S A;  4UU0 A;  2YFY A;  3A3Y A;  3TLM A;  5AVS A;  5AW8 A;  4Y3U A;  1SVJ A;  3N5K A;  3W5C A;  2C8L A;  2KMX A;  1MO8 A;  3FPS A;  2ARF A;  2O9J A;  4XE5 A;  2YJ5 A;  3A1E A;  5AW9 A;  1T5S A;  5AW4 A;  5AW5 A;  2ZBE A;  5AVU A;  5AVV A;  5AVY A;  2C8K A;  3W5B A;  2YJ4 A;  4BEV A;  1SU4 A;  4BYG A;  2AGV A;  5AW7 A;  1WPG A;  4BBJ A;  3AR3 A;  2EAT A;  5AW6 A;  3AR8 A;  3BA6 A;  2ZBF A;  3B9R A;  5AW1 A;  4NAB A;  4YCM A;  2YJ6 A;  4H1W A;  3A1D A;  4KYT A;  2ZBG A;  2EAR A;  3SKY A;  5AVR A;  2YJ3 A;  3WGU A;  2ZBD A;  5AVX A;  1T5T A;  4RET A;  1VFP A;  3AR9 A;  2C9M A;  3WGV A;  2C88 A;  3GWI A;  3AR5 A;  3J7T A;  1IWO A;  5A3Q A;  4J2T A;  3AR7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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