2KMXA

Solution structure of the nucleotide binding domain of the human menkes protein in the atp-bound form
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
185
structure length
185
Chain Sequence
SFTMHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Copper-transporting ATPase 1
total genus 39
structure length 185
sequence length 185
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2009-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1110.10 Alpha Beta 3-Layer(aba) Sandwich Calcium-transporting ATPase, cytoplasmic domain N Calcium-transporting ATPase, cytoplasmic domain N 2kmxA00
1T5SA 3A1EA 2EAUA 2ARFA 3SKYA 5AW6A 3AR7A 2YJ5A 3AR8A 4BBJA 3J7TA 3B8EA 5AVQA 5AVZA 3W5CA 4J2TA 5AW7A 4YCNA 2C88A 4NABA 5AVYA 3W5DA 5AW2A 1T5TA 2ZBFA 3FPSA 4YCLA 4BYGA 3WGUA 3B9BA 2BY4A 3RFUA 3NANA 2C8LA 2EARA 5AVWA 4KYTA 1MO7A 4XE5A 3WGVA 4BEWA 5AVXA 4UMVA 3AR5A 2EATA 2YJ3A 3AR3A 5AW4A 1IWOA 2O9JA 3N5KA 2B8EA 5AVTA 4HYTA 1U7QA 2DQSA 3A1CA 3AR9A 5AW8A 3W5BA 3B9RA 4UU0A 2ZBEA 2ZXEA 4Y3UA 2KMVA 1WPGA 3W5AA 1SU4A 3A3YA 3AR4A 1XP5A 1Q3IA 1SVJA 1MO8A 2C8KA 5AW1A 2YFYA 3FPBA 1VFPA 3NALA 5A3SA 3BA6A 2ZBGA 2C9MA 3SKXA 4UU1A 4RESA 2A00A 5AVRA 2AGVA 5A3QA 4H1WA 5AVVA 5AVUA 3KDPA 4YCMA 3AR2A 4RETA 5A3RA 2ZBDA 3AR6A 5AVSA 5AW0A 2YJ6A 4BEVA 2OA0A 3GWIA 3N8GA 2A29A 3FGOA 3NAMA 2YJ4A 5AW5A 2KMXA 3TLMA 3A1DA 4XOUA 2IYEA 5AW9A 5AW3A
chains in the Genus database with same CATH superfamily
1T5SA 3A1EA 2EAUA 2ARFA 3SKYA 5AW6A 3AR7A 2YJ5A 3AR8A 4BBJA 3J7TA 3B8EA 5AVQA 5AVZA 3W5CA 4J2TA 5AW7A 4YCNA 2C88A 4NABA 5AVYA 3W5DA 5AW2A 1T5TA 2ZBFA 3FPSA 4YCLA 4BYGA 3WGUA 3B9BA 2BY4A 3RFUA 3NANA 2C8LA 2EARA 5AVWA 4KYTA 1MO7A 4XE5A 3WGVA 4BEWA 5AVXA 4UMVA 3AR5A 2EATA 2YJ3A 3AR3A 5AW4A 1IWOA 2O9JA 3N5KA 2B8EA 5AVTA 4HYTA 1U7QA 2DQSA 3A1CA 3AR9A 5AW8A 3W5BA 3B9RA 4UU0A 2ZBEA 2ZXEA 4Y3UA 2KMVA 1WPGA 3W5AA 1SU4A 3A3YA 3AR4A 1XP5A 1Q3IA 1SVJA 1MO8A 2C8KA 5AW1A 2YFYA 3FPBA 1VFPA 3NALA 5A3SA 3BA6A 2ZBGA 2C9MA 3SKXA 4UU1A 4RESA 2A00A 5AVRA 2AGVA 5A3QA 4H1WA 5AVVA 5AVUA 3KDPA 4YCMA 3AR2A 4RETA 5A3RA 2ZBDA 3AR6A 5AVSA 5AW0A 2YJ6A 4BEVA 2OA0A 3GWIA 3N8GA 2A29A 3FGOA 3NAMA 2YJ4A 5AW5A 2KMXA 3TLMA 3A1DA 4XOUA 2IYEA 5AW9A 5AW3A
chains in the Genus database with same CATH topology
1T5SA 3A1EA 2EAUA 2ARFA 3SKYA 5AW6A 3AR7A 2YJ5A 3AR8A 4BBJA 3J7TA 3B8EA 5AVQA 5AVZA 3W5CA 4J2TA 5AW7A 4YCNA 2C88A 4NABA 5AVYA 3W5DA 5AW2A 1T5TA 2ZBFA 3FPSA 4YCLA 4BYGA 3WGUA 3B9BA 2BY4A 3RFUA 3NANA 2C8LA 2EARA 5AVWA 4KYTA 1MO7A 4XE5A 3WGVA 4BEWA 5AVXA 4UMVA 3AR5A 2EATA 2YJ3A 3AR3A 5AW4A 1IWOA 2O9JA 3N5KA 2B8EA 5AVTA 4HYTA 1U7QA 2DQSA 3A1CA 3AR9A 5AW8A 3W5BA 3B9RA 4UU0A 2ZBEA 2ZXEA 4Y3UA 2KMVA 1WPGA 3W5AA 1SU4A 3A3YA 3AR4A 1XP5A 1Q3IA 1SVJA 1MO8A 2C8KA 5AW1A 2YFYA 3FPBA 1VFPA 3NALA 5A3SA 3BA6A 2ZBGA 2C9MA 3SKXA 4UU1A 4RESA 2A00A 5AVRA 2AGVA 5A3QA 4H1WA 5AVVA 5AVUA 3KDPA 4YCMA 3AR2A 4RETA 5A3RA 2ZBDA 3AR6A 5AVSA 5AW0A 2YJ6A 4BEVA 2OA0A 3GWIA 3N8GA 2A29A 3FGOA 3NAMA 2YJ4A 5AW5A 2KMXA 3TLMA 3A1DA 4XOUA 2IYEA 5AW9A 5AW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T5S A;  3A1E A;  2EAU A;  2ARF A;  3SKY A;  5AW6 A;  3AR7 A;  2YJ5 A;  3AR8 A;  4BBJ A;  3J7T A;  3B8E A;  5AVQ A;  5AVZ A;  3W5C A;  4J2T A;  5AW7 A;  4YCN A;  2C88 A;  4NAB A;  5AVY A;  3W5D A;  5AW2 A;  1T5T A;  2ZBF A;  3FPS A;  4YCL A;  4BYG A;  3WGU A;  3B9B A;  2BY4 A;  3RFU A;  3NAN A;  2C8L A;  2EAR A;  5AVW A;  4KYT A;  1MO7 A;  4XE5 A;  3WGV A;  4BEW A;  5AVX A;  4UMV A;  3AR5 A;  2EAT A;  2YJ3 A;  3AR3 A;  5AW4 A;  1IWO A;  2O9J A;  3N5K A;  2B8E A;  5AVT A;  4HYT A;  1U7Q A;  2DQS A;  3A1C A;  3AR9 A;  5AW8 A;  3W5B A;  3B9R A;  4UU0 A;  2ZBE A;  2ZXE A;  4Y3U A;  2KMV A;  1WPG A;  3W5A A;  1SU4 A;  3A3Y A;  3AR4 A;  1XP5 A;  1Q3I A;  1SVJ A;  1MO8 A;  2C8K A;  5AW1 A;  2YFY A;  3FPB A;  1VFP A;  3NAL A;  5A3S A;  3BA6 A;  2ZBG A;  2C9M A;  3SKX A;  4UU1 A;  4RES A;  2A00 A;  5AVR A;  2AGV A;  5A3Q A;  4H1W A;  5AVV A;  5AVU A;  3KDP A;  4YCM A;  3AR2 A;  4RET A;  5A3R A;  2ZBD A;  3AR6 A;  5AVS A;  5AW0 A;  2YJ6 A;  4BEV A;  2OA0 A;  3GWI A;  3N8G A;  2A29 A;  3FGO A;  3NAM A;  2YJ4 A;  5AW5 A;  2KMX A;  3TLM A;  3A1D A;  4XOU A;  2IYE A;  5AW9 A;  5AW3 A; 
#chains in the Genus database with same CATH topology
 1T5S A;  3A1E A;  2EAU A;  2ARF A;  3SKY A;  5AW6 A;  3AR7 A;  2YJ5 A;  3AR8 A;  4BBJ A;  3J7T A;  3B8E A;  5AVQ A;  5AVZ A;  3W5C A;  4J2T A;  5AW7 A;  4YCN A;  2C88 A;  4NAB A;  5AVY A;  3W5D A;  5AW2 A;  1T5T A;  2ZBF A;  3FPS A;  4YCL A;  4BYG A;  3WGU A;  3B9B A;  2BY4 A;  3RFU A;  3NAN A;  2C8L A;  2EAR A;  5AVW A;  4KYT A;  1MO7 A;  4XE5 A;  3WGV A;  4BEW A;  5AVX A;  4UMV A;  3AR5 A;  2EAT A;  2YJ3 A;  3AR3 A;  5AW4 A;  1IWO A;  2O9J A;  3N5K A;  2B8E A;  5AVT A;  4HYT A;  1U7Q A;  2DQS A;  3A1C A;  3AR9 A;  5AW8 A;  3W5B A;  3B9R A;  4UU0 A;  2ZBE A;  2ZXE A;  4Y3U A;  2KMV A;  1WPG A;  3W5A A;  1SU4 A;  3A3Y A;  3AR4 A;  1XP5 A;  1Q3I A;  1SVJ A;  1MO8 A;  2C8K A;  5AW1 A;  2YFY A;  3FPB A;  1VFP A;  3NAL A;  5A3S A;  3BA6 A;  2ZBG A;  2C9M A;  3SKX A;  4UU1 A;  4RES A;  2A00 A;  5AVR A;  2AGV A;  5A3Q A;  4H1W A;  5AVV A;  5AVU A;  3KDP A;  4YCM A;  3AR2 A;  4RET A;  5A3R A;  2ZBD A;  3AR6 A;  5AVS A;  5AW0 A;  2YJ6 A;  4BEV A;  2OA0 A;  3GWI A;  3N8G A;  2A29 A;  3FGO A;  3NAM A;  2YJ4 A;  5AW5 A;  2KMX A;  3TLM A;  3A1D A;  4XOU A;  2IYE A;  5AW9 A;  5AW3 A; 
#chains in the Genus database with same CATH homology
 1T5S A;  3A1E A;  2EAU A;  2ARF A;  3SKY A;  5AW6 A;  3AR7 A;  2YJ5 A;  3AR8 A;  4BBJ A;  3J7T A;  3B8E A;  5AVQ A;  5AVZ A;  3W5C A;  4J2T A;  5AW7 A;  4YCN A;  2C88 A;  4NAB A;  5AVY A;  3W5D A;  5AW2 A;  1T5T A;  2ZBF A;  3FPS A;  4YCL A;  4BYG A;  3WGU A;  3B9B A;  2BY4 A;  3RFU A;  3NAN A;  2C8L A;  2EAR A;  5AVW A;  4KYT A;  1MO7 A;  4XE5 A;  3WGV A;  4BEW A;  5AVX A;  4UMV A;  3AR5 A;  2EAT A;  2YJ3 A;  3AR3 A;  5AW4 A;  1IWO A;  2O9J A;  3N5K A;  2B8E A;  5AVT A;  4HYT A;  1U7Q A;  2DQS A;  3A1C A;  3AR9 A;  5AW8 A;  3W5B A;  3B9R A;  4UU0 A;  2ZBE A;  2ZXE A;  4Y3U A;  2KMV A;  1WPG A;  3W5A A;  1SU4 A;  3A3Y A;  3AR4 A;  1XP5 A;  1Q3I A;  1SVJ A;  1MO8 A;  2C8K A;  5AW1 A;  2YFY A;  3FPB A;  1VFP A;  3NAL A;  5A3S A;  3BA6 A;  2ZBG A;  2C9M A;  3SKX A;  4UU1 A;  4RES A;  2A00 A;  5AVR A;  2AGV A;  5A3Q A;  4H1W A;  5AVV A;  5AVU A;  3KDP A;  4YCM A;  3AR2 A;  4RET A;  5A3R A;  2ZBD A;  3AR6 A;  5AVS A;  5AW0 A;  2YJ6 A;  4BEV A;  2OA0 A;  3GWI A;  3N8G A;  2A29 A;  3FGO A;  3NAM A;  2YJ4 A;  5AW5 A;  2KMX A;  3TLM A;  3A1D A;  4XOU A;  2IYE A;  5AW9 A;  5AW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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