2KMXA

Solution structure of the nucleotide binding domain of the human menkes protein in the atp-bound form
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
185
structure length
185
Chain Sequence
SFTMHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Copper-transporting ATPase 1
total genus 39
structure length 185
sequence length 185
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2009-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1110.10 Alpha Beta 3-Layer(aba) Sandwich Calcium-transporting ATPase, cytoplasmic domain N Calcium-transporting ATPase, cytoplasmic domain N 2kmxA00
2YJ5A 5AW9A 3N8GA 2B8EA 4BYGA 2O9JA 3A1DA 2A29A 3W5DA 2EAUA 2ZBFA 1MO8A 4RESA 4BEVA 4NABA 1VFPA 4RETA 4XOUA 2C88A 3NALA 1T5TA 4J2TA 4KYTA 4UU0A 1T5SA 3SKYA 3WGVA 2ZBGA 2EARA 4Y3UA 2C8KA 4HYTA 5AVZA 3AR4A 5AW7A 2DQSA 4YCNA 2AGVA 3W5CA 4YCLA 5AVSA 3AR5A 3N5KA 3SKXA 3AR3A 3AR9A 5AW5A 2C9MA 3AR7A 3NAMA 1WPGA 2YJ3A 3B8EA 2ZBDA 5A3SA 1XP5A 5AVRA 2ARFA 4UU1A 2OA0A 5AW0A 2IYEA 1MO7A 5AVUA 5AVTA 5AVYA 4BEWA 5AVVA 4XE5A 2A00A 3W5AA 5A3RA 3NANA 2ZBEA 2YJ4A 3FGOA 5AVWA 3FPBA 3TLMA 4YCMA 3WGUA 4UMVA 5AW2A 1SVJA 3W5BA 2KMXA 5AW4A 5AW1A 3AR8A 3BA6A 5AVQA 5AVXA 5AW6A 3B9BA 3GWIA 3AR2A 1SU4A 1Q3IA 3KDPA 2YFYA 3A1EA 3AR6A 1U7QA 3A1CA 2C8LA 4BBJA 2YJ6A 2EATA 3B9RA 3FPSA 3A3YA 4H1WA 2KMVA 1IWOA 3RFUA 5AW8A 3J7TA 2BY4A 5AW3A 2ZXEA 5A3QA
chains in the Genus database with same CATH superfamily
2YJ5A 5AW9A 3N8GA 2B8EA 4BYGA 2O9JA 3A1DA 2A29A 3W5DA 2EAUA 2ZBFA 1MO8A 4RESA 4BEVA 4NABA 1VFPA 4RETA 4XOUA 2C88A 3NALA 1T5TA 4J2TA 4KYTA 4UU0A 1T5SA 3SKYA 3WGVA 2ZBGA 2EARA 4Y3UA 2C8KA 4HYTA 5AVZA 3AR4A 5AW7A 2DQSA 4YCNA 2AGVA 3W5CA 4YCLA 5AVSA 3AR5A 3N5KA 3SKXA 3AR3A 3AR9A 5AW5A 2C9MA 3AR7A 3NAMA 1WPGA 2YJ3A 3B8EA 2ZBDA 5A3SA 1XP5A 5AVRA 2ARFA 4UU1A 2OA0A 5AW0A 2IYEA 1MO7A 5AVUA 5AVTA 5AVYA 4BEWA 5AVVA 4XE5A 2A00A 3W5AA 5A3RA 3NANA 2ZBEA 2YJ4A 3FGOA 5AVWA 3FPBA 3TLMA 4YCMA 3WGUA 4UMVA 5AW2A 1SVJA 3W5BA 2KMXA 5AW4A 5AW1A 3AR8A 3BA6A 5AVQA 5AVXA 5AW6A 3B9BA 3GWIA 3AR2A 1SU4A 1Q3IA 3KDPA 2YFYA 3A1EA 3AR6A 1U7QA 3A1CA 2C8LA 4BBJA 2YJ6A 2EATA 3B9RA 3FPSA 3A3YA 4H1WA 2KMVA 1IWOA 3RFUA 5AW8A 3J7TA 2BY4A 5AW3A 2ZXEA 5A3QA
chains in the Genus database with same CATH topology
2YJ5A 5AW9A 3N8GA 2B8EA 4BYGA 2O9JA 3A1DA 2A29A 3W5DA 2EAUA 2ZBFA 1MO8A 4RESA 4BEVA 4NABA 1VFPA 4RETA 4XOUA 2C88A 3NALA 1T5TA 4J2TA 4KYTA 4UU0A 1T5SA 3SKYA 3WGVA 2ZBGA 2EARA 4Y3UA 2C8KA 4HYTA 5AVZA 3AR4A 5AW7A 2DQSA 4YCNA 2AGVA 3W5CA 4YCLA 5AVSA 3AR5A 3N5KA 3SKXA 3AR3A 3AR9A 5AW5A 2C9MA 3AR7A 3NAMA 1WPGA 2YJ3A 3B8EA 2ZBDA 5A3SA 1XP5A 5AVRA 2ARFA 4UU1A 2OA0A 5AW0A 2IYEA 1MO7A 5AVUA 5AVTA 5AVYA 4BEWA 5AVVA 4XE5A 2A00A 3W5AA 5A3RA 3NANA 2ZBEA 2YJ4A 3FGOA 5AVWA 3FPBA 3TLMA 4YCMA 3WGUA 4UMVA 5AW2A 1SVJA 3W5BA 2KMXA 5AW4A 5AW1A 3AR8A 3BA6A 5AVQA 5AVXA 5AW6A 3B9BA 3GWIA 3AR2A 1SU4A 1Q3IA 3KDPA 2YFYA 3A1EA 3AR6A 1U7QA 3A1CA 2C8LA 4BBJA 2YJ6A 2EATA 3B9RA 3FPSA 3A3YA 4H1WA 2KMVA 1IWOA 3RFUA 5AW8A 3J7TA 2BY4A 5AW3A 2ZXEA 5A3QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YJ5 A;  5AW9 A;  3N8G A;  2B8E A;  4BYG A;  2O9J A;  3A1D A;  2A29 A;  3W5D A;  2EAU A;  2ZBF A;  1MO8 A;  4RES A;  4BEV A;  4NAB A;  1VFP A;  4RET A;  4XOU A;  2C88 A;  3NAL A;  1T5T A;  4J2T A;  4KYT A;  4UU0 A;  1T5S A;  3SKY A;  3WGV A;  2ZBG A;  2EAR A;  4Y3U A;  2C8K A;  4HYT A;  5AVZ A;  3AR4 A;  5AW7 A;  2DQS A;  4YCN A;  2AGV A;  3W5C A;  4YCL A;  5AVS A;  3AR5 A;  3N5K A;  3SKX A;  3AR3 A;  3AR9 A;  5AW5 A;  2C9M A;  3AR7 A;  3NAM A;  1WPG A;  2YJ3 A;  3B8E A;  2ZBD A;  5A3S A;  1XP5 A;  5AVR A;  2ARF A;  4UU1 A;  2OA0 A;  5AW0 A;  2IYE A;  1MO7 A;  5AVU A;  5AVT A;  5AVY A;  4BEW A;  5AVV A;  4XE5 A;  2A00 A;  3W5A A;  5A3R A;  3NAN A;  2ZBE A;  2YJ4 A;  3FGO A;  5AVW A;  3FPB A;  3TLM A;  4YCM A;  3WGU A;  4UMV A;  5AW2 A;  1SVJ A;  3W5B A;  2KMX A;  5AW4 A;  5AW1 A;  3AR8 A;  3BA6 A;  5AVQ A;  5AVX A;  5AW6 A;  3B9B A;  3GWI A;  3AR2 A;  1SU4 A;  1Q3I A;  3KDP A;  2YFY A;  3A1E A;  3AR6 A;  1U7Q A;  3A1C A;  2C8L A;  4BBJ A;  2YJ6 A;  2EAT A;  3B9R A;  3FPS A;  3A3Y A;  4H1W A;  2KMV A;  1IWO A;  3RFU A;  5AW8 A;  3J7T A;  2BY4 A;  5AW3 A;  2ZXE A;  5A3Q A; 
#chains in the Genus database with same CATH topology
 2YJ5 A;  5AW9 A;  3N8G A;  2B8E A;  4BYG A;  2O9J A;  3A1D A;  2A29 A;  3W5D A;  2EAU A;  2ZBF A;  1MO8 A;  4RES A;  4BEV A;  4NAB A;  1VFP A;  4RET A;  4XOU A;  2C88 A;  3NAL A;  1T5T A;  4J2T A;  4KYT A;  4UU0 A;  1T5S A;  3SKY A;  3WGV A;  2ZBG A;  2EAR A;  4Y3U A;  2C8K A;  4HYT A;  5AVZ A;  3AR4 A;  5AW7 A;  2DQS A;  4YCN A;  2AGV A;  3W5C A;  4YCL A;  5AVS A;  3AR5 A;  3N5K A;  3SKX A;  3AR3 A;  3AR9 A;  5AW5 A;  2C9M A;  3AR7 A;  3NAM A;  1WPG A;  2YJ3 A;  3B8E A;  2ZBD A;  5A3S A;  1XP5 A;  5AVR A;  2ARF A;  4UU1 A;  2OA0 A;  5AW0 A;  2IYE A;  1MO7 A;  5AVU A;  5AVT A;  5AVY A;  4BEW A;  5AVV A;  4XE5 A;  2A00 A;  3W5A A;  5A3R A;  3NAN A;  2ZBE A;  2YJ4 A;  3FGO A;  5AVW A;  3FPB A;  3TLM A;  4YCM A;  3WGU A;  4UMV A;  5AW2 A;  1SVJ A;  3W5B A;  2KMX A;  5AW4 A;  5AW1 A;  3AR8 A;  3BA6 A;  5AVQ A;  5AVX A;  5AW6 A;  3B9B A;  3GWI A;  3AR2 A;  1SU4 A;  1Q3I A;  3KDP A;  2YFY A;  3A1E A;  3AR6 A;  1U7Q A;  3A1C A;  2C8L A;  4BBJ A;  2YJ6 A;  2EAT A;  3B9R A;  3FPS A;  3A3Y A;  4H1W A;  2KMV A;  1IWO A;  3RFU A;  5AW8 A;  3J7T A;  2BY4 A;  5AW3 A;  2ZXE A;  5A3Q A; 
#chains in the Genus database with same CATH homology
 2YJ5 A;  5AW9 A;  3N8G A;  2B8E A;  4BYG A;  2O9J A;  3A1D A;  2A29 A;  3W5D A;  2EAU A;  2ZBF A;  1MO8 A;  4RES A;  4BEV A;  4NAB A;  1VFP A;  4RET A;  4XOU A;  2C88 A;  3NAL A;  1T5T A;  4J2T A;  4KYT A;  4UU0 A;  1T5S A;  3SKY A;  3WGV A;  2ZBG A;  2EAR A;  4Y3U A;  2C8K A;  4HYT A;  5AVZ A;  3AR4 A;  5AW7 A;  2DQS A;  4YCN A;  2AGV A;  3W5C A;  4YCL A;  5AVS A;  3AR5 A;  3N5K A;  3SKX A;  3AR3 A;  3AR9 A;  5AW5 A;  2C9M A;  3AR7 A;  3NAM A;  1WPG A;  2YJ3 A;  3B8E A;  2ZBD A;  5A3S A;  1XP5 A;  5AVR A;  2ARF A;  4UU1 A;  2OA0 A;  5AW0 A;  2IYE A;  1MO7 A;  5AVU A;  5AVT A;  5AVY A;  4BEW A;  5AVV A;  4XE5 A;  2A00 A;  3W5A A;  5A3R A;  3NAN A;  2ZBE A;  2YJ4 A;  3FGO A;  5AVW A;  3FPB A;  3TLM A;  4YCM A;  3WGU A;  4UMV A;  5AW2 A;  1SVJ A;  3W5B A;  2KMX A;  5AW4 A;  5AW1 A;  3AR8 A;  3BA6 A;  5AVQ A;  5AVX A;  5AW6 A;  3B9B A;  3GWI A;  3AR2 A;  1SU4 A;  1Q3I A;  3KDP A;  2YFY A;  3A1E A;  3AR6 A;  1U7Q A;  3A1C A;  2C8L A;  4BBJ A;  2YJ6 A;  2EAT A;  3B9R A;  3FPS A;  3A3Y A;  4H1W A;  2KMV A;  1IWO A;  3RFU A;  5AW8 A;  3J7T A;  2BY4 A;  5AW3 A;  2ZXE A;  5A3Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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