2OPZA

Avpf bound to bir3-xiap
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
109
structure length
109
Chain Sequence
NFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP.
pubmed doi rcsb
molecule tags Apoptosis inhibitor
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 33
structure length 109
sequence length 109
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 2opzA00
2UVLA 2I3HA 1JD6A 3OZ1A 4WVSA 3T6PA 1Q4QA 1TFQA 2I3IA 3CM7A 3D9UA 4MTZA 2OPYA 3UEEA 3F7IA 3D9TA 1XOXA 2POPB 3UEHA 3M0AD 4MU7A 2QFAA 1XB1A 2RAXA 4HY5A 3UEIA 3M1DA 4HY0A 5C7CA 1OXNA 4KJVA 4LGEA 3UIKA 3HL5A 4A0JA 3UECA 5C7DA 3GTAA 3SIQA 1OY7A 4MTIA 4LGUA 1NW9A 1G73C 3SIPE 5C3HA 3CM2A 4WVUA 4J46A 3UEDA 2JK7A 3UW4A 1M4MA 2OPZA 1TW6A 2VSLA 4KMNA 4A0NA 2QRAA 3CLXA 3F7GA 1F9XA 3UEGA 4HY4A 2RAWA 3F7HA 1SE0A 4J3YA 4EC4A 5C7AA 3M0DD 5C3KA 1OXQA 4A0IA 4J47A 4WVTA 3UIJA 1I3OE 4J48A 3UIHA 3UW5A 4EB9A 1JD5A 4OXCA 1E31A 3MUPA 2POIA 5C84A 2VM5A 1TFTA 4KJUA 3G76A 1C9QA 5C0LA 5C0KA 4J44A 3UEFA 3GT9A 4J45A 1F3HA 1QBHA 4KMPA 3UIGA 1G3FA 3EYLA 5C83A 1JD4A 5C7BA 3UIIA 1XB0A 1SDZA
chains in the Genus database with same CATH superfamily
2UVLA 2I3HA 1JD6A 3OZ1A 4WVSA 3T6PA 1Q4QA 1TFQA 2I3IA 3CM7A 3D9UA 4MTZA 2OPYA 3UEEA 3F7IA 3D9TA 1XOXA 2POPB 3UEHA 3M0AD 4MU7A 2QFAA 1XB1A 2RAXA 4HY5A 3UEIA 3M1DA 4HY0A 5C7CA 1OXNA 4KJVA 4LGEA 3UIKA 3HL5A 4A0JA 3UECA 5C7DA 3GTAA 3SIQA 1OY7A 4MTIA 4LGUA 1NW9A 1G73C 3SIPE 5C3HA 3CM2A 4WVUA 4J46A 3UEDA 2JK7A 3UW4A 1M4MA 2OPZA 1TW6A 2VSLA 4KMNA 4A0NA 2QRAA 3CLXA 3F7GA 1F9XA 3UEGA 4HY4A 2RAWA 3F7HA 1SE0A 4J3YA 4EC4A 5C7AA 3M0DD 5C3KA 1OXQA 4A0IA 4J47A 4WVTA 3UIJA 1I3OE 4J48A 3UIHA 3UW5A 4EB9A 1JD5A 4OXCA 1E31A 3MUPA 2POIA 5C84A 2VM5A 1TFTA 4KJUA 3G76A 1C9QA 5C0LA 5C0KA 4J44A 3UEFA 3GT9A 4J45A 1F3HA 1QBHA 4KMPA 3UIGA 1G3FA 3EYLA 5C83A 1JD4A 5C7BA 3UIIA 1XB0A 1SDZA
chains in the Genus database with same CATH topology
2UVLA 2I3HA 1JD6A 3OZ1A 4WVSA 3T6PA 1Q4QA 1TFQA 2I3IA 3CM7A 3D9UA 4MTZA 2OPYA 3UEEA 3F7IA 3D9TA 1XOXA 2POPB 3UEHA 3M0AD 4MU7A 2QFAA 1XB1A 2RAXA 4HY5A 3UEIA 3M1DA 4HY0A 5C7CA 1OXNA 4KJVA 4LGEA 3UIKA 3HL5A 4A0JA 3UECA 5C7DA 3GTAA 3SIQA 1OY7A 4MTIA 4LGUA 1NW9A 1G73C 3SIPE 5C3HA 3CM2A 4WVUA 4J46A 3UEDA 2JK7A 3UW4A 1M4MA 2OPZA 1TW6A 2VSLA 4KMNA 4A0NA 2QRAA 3CLXA 3F7GA 1F9XA 3UEGA 4HY4A 2RAWA 3F7HA 1SE0A 4J3YA 4EC4A 5C7AA 3M0DD 5C3KA 1OXQA 4A0IA 4J47A 4WVTA 3UIJA 1I3OE 4J48A 3UIHA 3UW5A 4EB9A 1JD5A 4OXCA 1E31A 3MUPA 2POIA 5C84A 2VM5A 1TFTA 4KJUA 3G76A 1C9QA 5C0LA 5C0KA 4J44A 3UEFA 3GT9A 4J45A 1F3HA 1QBHA 4KMPA 3UIGA 1G3FA 3EYLA 5C83A 1JD4A 5C7BA 3UIIA 1XB0A 1SDZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2UVL A;  2I3H A;  1JD6 A;  3OZ1 A;  4WVS A;  3T6P A;  1Q4Q A;  1TFQ A;  2I3I A;  3CM7 A;  3D9U A;  4MTZ A;  2OPY A;  3UEE A;  3F7I A;  3D9T A;  1XOX A;  2POP B;  3UEH A;  3M0A D;  4MU7 A;  2QFA A;  1XB1 A;  2RAX A;  4HY5 A;  3UEI A;  3M1D A;  4HY0 A;  5C7C A;  1OXN A;  4KJV A;  4LGE A;  3UIK A;  3HL5 A;  4A0J A;  3UEC A;  5C7D A;  3GTA A;  3SIQ A;  1OY7 A;  4MTI A;  4LGU A;  1NW9 A;  1G73 C;  3SIP E;  5C3H A;  3CM2 A;  4WVU A;  4J46 A;  3UED A;  2JK7 A;  3UW4 A;  1M4M A;  2OPZ A;  1TW6 A;  2VSL A;  4KMN A;  4A0N A;  2QRA A;  3CLX A;  3F7G A;  1F9X A;  3UEG A;  4HY4 A;  2RAW A;  3F7H A;  1SE0 A;  4J3Y A;  4EC4 A;  5C7A A;  3M0D D;  5C3K A;  1OXQ A;  4A0I A;  4J47 A;  4WVT A;  3UIJ A;  1I3O E;  4J48 A;  3UIH A;  3UW5 A;  4EB9 A;  1JD5 A;  4OXC A;  1E31 A;  3MUP A;  2POI A;  5C84 A;  2VM5 A;  1TFT A;  4KJU A;  3G76 A;  1C9Q A;  5C0L A;  5C0K A;  4J44 A;  3UEF A;  3GT9 A;  4J45 A;  1F3H A;  1QBH A;  4KMP A;  3UIG A;  1G3F A;  3EYL A;  5C83 A;  1JD4 A;  5C7B A;  3UII A;  1XB0 A;  1SDZ A; 
#chains in the Genus database with same CATH topology
 2UVL A;  2I3H A;  1JD6 A;  3OZ1 A;  4WVS A;  3T6P A;  1Q4Q A;  1TFQ A;  2I3I A;  3CM7 A;  3D9U A;  4MTZ A;  2OPY A;  3UEE A;  3F7I A;  3D9T A;  1XOX A;  2POP B;  3UEH A;  3M0A D;  4MU7 A;  2QFA A;  1XB1 A;  2RAX A;  4HY5 A;  3UEI A;  3M1D A;  4HY0 A;  5C7C A;  1OXN A;  4KJV A;  4LGE A;  3UIK A;  3HL5 A;  4A0J A;  3UEC A;  5C7D A;  3GTA A;  3SIQ A;  1OY7 A;  4MTI A;  4LGU A;  1NW9 A;  1G73 C;  3SIP E;  5C3H A;  3CM2 A;  4WVU A;  4J46 A;  3UED A;  2JK7 A;  3UW4 A;  1M4M A;  2OPZ A;  1TW6 A;  2VSL A;  4KMN A;  4A0N A;  2QRA A;  3CLX A;  3F7G A;  1F9X A;  3UEG A;  4HY4 A;  2RAW A;  3F7H A;  1SE0 A;  4J3Y A;  4EC4 A;  5C7A A;  3M0D D;  5C3K A;  1OXQ A;  4A0I A;  4J47 A;  4WVT A;  3UIJ A;  1I3O E;  4J48 A;  3UIH A;  3UW5 A;  4EB9 A;  1JD5 A;  4OXC A;  1E31 A;  3MUP A;  2POI A;  5C84 A;  2VM5 A;  1TFT A;  4KJU A;  3G76 A;  1C9Q A;  5C0L A;  5C0K A;  4J44 A;  3UEF A;  3GT9 A;  4J45 A;  1F3H A;  1QBH A;  4KMP A;  3UIG A;  1G3F A;  3EYL A;  5C83 A;  1JD4 A;  5C7B A;  3UII A;  1XB0 A;  1SDZ A; 
#chains in the Genus database with same CATH homology
 2UVL A;  2I3H A;  1JD6 A;  3OZ1 A;  4WVS A;  3T6P A;  1Q4Q A;  1TFQ A;  2I3I A;  3CM7 A;  3D9U A;  4MTZ A;  2OPY A;  3UEE A;  3F7I A;  3D9T A;  1XOX A;  2POP B;  3UEH A;  3M0A D;  4MU7 A;  2QFA A;  1XB1 A;  2RAX A;  4HY5 A;  3UEI A;  3M1D A;  4HY0 A;  5C7C A;  1OXN A;  4KJV A;  4LGE A;  3UIK A;  3HL5 A;  4A0J A;  3UEC A;  5C7D A;  3GTA A;  3SIQ A;  1OY7 A;  4MTI A;  4LGU A;  1NW9 A;  1G73 C;  3SIP E;  5C3H A;  3CM2 A;  4WVU A;  4J46 A;  3UED A;  2JK7 A;  3UW4 A;  1M4M A;  2OPZ A;  1TW6 A;  2VSL A;  4KMN A;  4A0N A;  2QRA A;  3CLX A;  3F7G A;  1F9X A;  3UEG A;  4HY4 A;  2RAW A;  3F7H A;  1SE0 A;  4J3Y A;  4EC4 A;  5C7A A;  3M0D D;  5C3K A;  1OXQ A;  4A0I A;  4J47 A;  4WVT A;  3UIJ A;  1I3O E;  4J48 A;  3UIH A;  3UW5 A;  4EB9 A;  1JD5 A;  4OXC A;  1E31 A;  3MUP A;  2POI A;  5C84 A;  2VM5 A;  1TFT A;  4KJU A;  3G76 A;  1C9Q A;  5C0L A;  5C0K A;  4J44 A;  3UEF A;  3GT9 A;  4J45 A;  1F3H A;  1QBH A;  4KMP A;  3UIG A;  1G3F A;  3EYL A;  5C83 A;  1JD4 A;  5C7B A;  3UII A;  1XB0 A;  1SDZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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