2QRAA

Crystal structure of xiap bir1 domain (p21 form)
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
80
structure length
80
Chain Sequence
EEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the BIR1 domain of XIAP in two crystal forms
pubmed doi rcsb
molecule tags Apoptosis, signaling protein
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 23
structure length 80
sequence length 80
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 2qraA00
3MUPA 3SIPE 2I3IA 1Q4QA 3HL5A 2UVLA 1JD4A 1C9QA 4LGUA 3CM7A 4MTIA 2JK7A 3UEFA 1QBHA 3UIJA 5C83A 4J3YA 3OZ1A 1JD5A 3T6PA 3UW4A 4EC4A 3UEHA 3M1DA 1SDZA 3UEDA 3UW5A 4J48A 3UIGA 4J46A 2QFAA 4A0JA 4EB9A 3D9UA 3UIHA 4A0NA 3SIQA 1TW6A 1F9XA 3F7HA 2QRAA 3CLXA 1I3OE 3CM2A 4OXCA 2I3HA 3EYLA 3UIIA 1XOXA 3UIKA 5C7AA 1TFTA 4A0IA 4HY4A 5C3KA 1OXNA 4J45A 2POPB 3UEGA 5C3HA 5C84A 3M0DD 2OPYA 2RAXA 4HY5A 4LGEA 4KMPA 1G3FA 2OPZA 1E31A 4J44A 2POIA 1JD6A 3F7IA 4KJVA 1TFQA 1XB1A 1F3HA 2RAWA 3UEEA 1G73C 4MU7A 1OXQA 3UECA 1OY7A 5C7BA 1M4MA 3M0AD 4MTZA 1XB0A 4KMNA 5C7CA 4J47A 5C0KA 1SE0A 4KJUA 5C0LA 3G76A 4HY0A 3GT9A 2VM5A 4WVTA 4WVSA 3GTAA 5C7DA 1NW9A 4WVUA 3D9TA 3F7GA 3UEIA 2VSLA
chains in the Genus database with same CATH superfamily
3MUPA 3SIPE 2I3IA 1Q4QA 3HL5A 2UVLA 1JD4A 1C9QA 4LGUA 3CM7A 4MTIA 2JK7A 3UEFA 1QBHA 3UIJA 5C83A 4J3YA 3OZ1A 1JD5A 3T6PA 3UW4A 4EC4A 3UEHA 3M1DA 1SDZA 3UEDA 3UW5A 4J48A 3UIGA 4J46A 2QFAA 4A0JA 4EB9A 3D9UA 3UIHA 4A0NA 3SIQA 1TW6A 1F9XA 3F7HA 2QRAA 3CLXA 1I3OE 3CM2A 4OXCA 2I3HA 3EYLA 3UIIA 1XOXA 3UIKA 5C7AA 1TFTA 4A0IA 4HY4A 5C3KA 1OXNA 4J45A 2POPB 3UEGA 5C3HA 5C84A 3M0DD 2OPYA 2RAXA 4HY5A 4LGEA 4KMPA 1G3FA 2OPZA 1E31A 4J44A 2POIA 1JD6A 3F7IA 4KJVA 1TFQA 1XB1A 1F3HA 2RAWA 3UEEA 1G73C 4MU7A 1OXQA 3UECA 1OY7A 5C7BA 1M4MA 3M0AD 4MTZA 1XB0A 4KMNA 5C7CA 4J47A 5C0KA 1SE0A 4KJUA 5C0LA 3G76A 4HY0A 3GT9A 2VM5A 4WVTA 4WVSA 3GTAA 5C7DA 1NW9A 4WVUA 3D9TA 3F7GA 3UEIA 2VSLA
chains in the Genus database with same CATH topology
3MUPA 3SIPE 2I3IA 1Q4QA 3HL5A 2UVLA 1JD4A 1C9QA 4LGUA 3CM7A 4MTIA 2JK7A 3UEFA 1QBHA 3UIJA 5C83A 4J3YA 3OZ1A 1JD5A 3T6PA 3UW4A 4EC4A 3UEHA 3M1DA 1SDZA 3UEDA 3UW5A 4J48A 3UIGA 4J46A 2QFAA 4A0JA 4EB9A 3D9UA 3UIHA 4A0NA 3SIQA 1TW6A 1F9XA 3F7HA 2QRAA 3CLXA 1I3OE 3CM2A 4OXCA 2I3HA 3EYLA 3UIIA 1XOXA 3UIKA 5C7AA 1TFTA 4A0IA 4HY4A 5C3KA 1OXNA 4J45A 2POPB 3UEGA 5C3HA 5C84A 3M0DD 2OPYA 2RAXA 4HY5A 4LGEA 4KMPA 1G3FA 2OPZA 1E31A 4J44A 2POIA 1JD6A 3F7IA 4KJVA 1TFQA 1XB1A 1F3HA 2RAWA 3UEEA 1G73C 4MU7A 1OXQA 3UECA 1OY7A 5C7BA 1M4MA 3M0AD 4MTZA 1XB0A 4KMNA 5C7CA 4J47A 5C0KA 1SE0A 4KJUA 5C0LA 3G76A 4HY0A 3GT9A 2VM5A 4WVTA 4WVSA 3GTAA 5C7DA 1NW9A 4WVUA 3D9TA 3F7GA 3UEIA 2VSLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MUP A;  3SIP E;  2I3I A;  1Q4Q A;  3HL5 A;  2UVL A;  1JD4 A;  1C9Q A;  4LGU A;  3CM7 A;  4MTI A;  2JK7 A;  3UEF A;  1QBH A;  3UIJ A;  5C83 A;  4J3Y A;  3OZ1 A;  1JD5 A;  3T6P A;  3UW4 A;  4EC4 A;  3UEH A;  3M1D A;  1SDZ A;  3UED A;  3UW5 A;  4J48 A;  3UIG A;  4J46 A;  2QFA A;  4A0J A;  4EB9 A;  3D9U A;  3UIH A;  4A0N A;  3SIQ A;  1TW6 A;  1F9X A;  3F7H A;  2QRA A;  3CLX A;  1I3O E;  3CM2 A;  4OXC A;  2I3H A;  3EYL A;  3UII A;  1XOX A;  3UIK A;  5C7A A;  1TFT A;  4A0I A;  4HY4 A;  5C3K A;  1OXN A;  4J45 A;  2POP B;  3UEG A;  5C3H A;  5C84 A;  3M0D D;  2OPY A;  2RAX A;  4HY5 A;  4LGE A;  4KMP A;  1G3F A;  2OPZ A;  1E31 A;  4J44 A;  2POI A;  1JD6 A;  3F7I A;  4KJV A;  1TFQ A;  1XB1 A;  1F3H A;  2RAW A;  3UEE A;  1G73 C;  4MU7 A;  1OXQ A;  3UEC A;  1OY7 A;  5C7B A;  1M4M A;  3M0A D;  4MTZ A;  1XB0 A;  4KMN A;  5C7C A;  4J47 A;  5C0K A;  1SE0 A;  4KJU A;  5C0L A;  3G76 A;  4HY0 A;  3GT9 A;  2VM5 A;  4WVT A;  4WVS A;  3GTA A;  5C7D A;  1NW9 A;  4WVU A;  3D9T A;  3F7G A;  3UEI A;  2VSL A; 
#chains in the Genus database with same CATH topology
 3MUP A;  3SIP E;  2I3I A;  1Q4Q A;  3HL5 A;  2UVL A;  1JD4 A;  1C9Q A;  4LGU A;  3CM7 A;  4MTI A;  2JK7 A;  3UEF A;  1QBH A;  3UIJ A;  5C83 A;  4J3Y A;  3OZ1 A;  1JD5 A;  3T6P A;  3UW4 A;  4EC4 A;  3UEH A;  3M1D A;  1SDZ A;  3UED A;  3UW5 A;  4J48 A;  3UIG A;  4J46 A;  2QFA A;  4A0J A;  4EB9 A;  3D9U A;  3UIH A;  4A0N A;  3SIQ A;  1TW6 A;  1F9X A;  3F7H A;  2QRA A;  3CLX A;  1I3O E;  3CM2 A;  4OXC A;  2I3H A;  3EYL A;  3UII A;  1XOX A;  3UIK A;  5C7A A;  1TFT A;  4A0I A;  4HY4 A;  5C3K A;  1OXN A;  4J45 A;  2POP B;  3UEG A;  5C3H A;  5C84 A;  3M0D D;  2OPY A;  2RAX A;  4HY5 A;  4LGE A;  4KMP A;  1G3F A;  2OPZ A;  1E31 A;  4J44 A;  2POI A;  1JD6 A;  3F7I A;  4KJV A;  1TFQ A;  1XB1 A;  1F3H A;  2RAW A;  3UEE A;  1G73 C;  4MU7 A;  1OXQ A;  3UEC A;  1OY7 A;  5C7B A;  1M4M A;  3M0A D;  4MTZ A;  1XB0 A;  4KMN A;  5C7C A;  4J47 A;  5C0K A;  1SE0 A;  4KJU A;  5C0L A;  3G76 A;  4HY0 A;  3GT9 A;  2VM5 A;  4WVT A;  4WVS A;  3GTA A;  5C7D A;  1NW9 A;  4WVU A;  3D9T A;  3F7G A;  3UEI A;  2VSL A; 
#chains in the Genus database with same CATH homology
 3MUP A;  3SIP E;  2I3I A;  1Q4Q A;  3HL5 A;  2UVL A;  1JD4 A;  1C9Q A;  4LGU A;  3CM7 A;  4MTI A;  2JK7 A;  3UEF A;  1QBH A;  3UIJ A;  5C83 A;  4J3Y A;  3OZ1 A;  1JD5 A;  3T6P A;  3UW4 A;  4EC4 A;  3UEH A;  3M1D A;  1SDZ A;  3UED A;  3UW5 A;  4J48 A;  3UIG A;  4J46 A;  2QFA A;  4A0J A;  4EB9 A;  3D9U A;  3UIH A;  4A0N A;  3SIQ A;  1TW6 A;  1F9X A;  3F7H A;  2QRA A;  3CLX A;  1I3O E;  3CM2 A;  4OXC A;  2I3H A;  3EYL A;  3UII A;  1XOX A;  3UIK A;  5C7A A;  1TFT A;  4A0I A;  4HY4 A;  5C3K A;  1OXN A;  4J45 A;  2POP B;  3UEG A;  5C3H A;  5C84 A;  3M0D D;  2OPY A;  2RAX A;  4HY5 A;  4LGE A;  4KMP A;  1G3F A;  2OPZ A;  1E31 A;  4J44 A;  2POI A;  1JD6 A;  3F7I A;  4KJV A;  1TFQ A;  1XB1 A;  1F3H A;  2RAW A;  3UEE A;  1G73 C;  4MU7 A;  1OXQ A;  3UEC A;  1OY7 A;  5C7B A;  1M4M A;  3M0A D;  4MTZ A;  1XB0 A;  4KMN A;  5C7C A;  4J47 A;  5C0K A;  1SE0 A;  4KJU A;  5C0L A;  3G76 A;  4HY0 A;  3GT9 A;  2VM5 A;  4WVT A;  4WVS A;  3GTA A;  5C7D A;  1NW9 A;  4WVU A;  3D9T A;  3F7G A;  3UEI A;  2VSL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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